Isolation and preliminary characterization of the medium-chain fatty acid:CoA ligase responsible for activation of short- and medium-chain fatty acids in colonic mucosa from swine

Digestive Diseases and Sciences

Volumn 46, Issue 2, 2001, Pages 438-442

  Vessey, Donald A ^a,b  

^a SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Butyrate; Colonic mucosa; Medium chain fatty acid:CoA ligase; Medium chain fatty acids; Short chain fatty acids

Indexed keywords

ACYL COENZYME A; ADENOSINE TRIPHOSPHATE; BENZOIC ACID; BUTYRIC ACID; CARBOXYLIC ACID; CYCLOHEXANE; LAURIC ACID; LIGASE; MEDIUM CHAIN FATTY ACID; MEDIUM CHAIN FATTY ACID COENZYME A LIGASE; OCTANOIC ACID; PROPIONIC ACID; SALICYLIC ACID; SHORT CHAIN FATTY ACID; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL FREE SYSTEM; COLON MUCOSA; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME ISOLATION; ENZYME KINETICS; ENZYME LOCALIZATION; ENZYME PURIFICATION; GEL FILTRATION CHROMATOGRAPHY; MICHAELIS CONSTANT; MITOCHONDRION; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL;

ACETATE-COA LIGASE; ANIMALS; CELL FRACTIONATION; CHROMATOGRAPHY, GEL; COLON; FATTY ACIDS, VOLATILE; INTESTINAL MUCOSA; MITOCHONDRIA; MOLECULAR WEIGHT; RATS; SUBSTRATE SPECIFICITY; SWINE;

EID: 0035080201     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005677521373     Document Type: Article

References (25)

1. Colonic short-chain fatty acids: Fuel from the lumen
2. Utilization of nutrients by isolated epithelial cell of the rat colon
3. Fuel utilization in colonocytes of the rat
4. Nutrient utilization by cells isolated from rat jejunum, cecum and colon
5. In vivo analysis of faeces as a method of stool analysis. IV. The organic anion component
6. Faecal short-chain fatty acids in patients with antibiotic-associated diarrhoea, before and after faecal enema treatment
7. Increasing butyrate concentration in the distal colon by accelerating intestinal transit
8. Different fibers have different regional effects on luminal contents of rat colon
9. 8 fatty acids in Sprague-Dawley rat colonocytes
10. Treatment of diversion colitis with short-chain fatty acid irrigation
11. Effects of intraluminal infusion of short-chain fatty acids on the healing of colonic anastomosis in the rat
12. Metabolic inductiion of experimental ulcerative colitis by inhibition of fatty acid oxidation
13. Colonic sulfide in pathogenesis and treatment of ulcerative colitis
14. Failure of colonic mucosa to oxidise butyrate in ulcerative colitis
15. 5-Aminosalicylic acid (5-ASA) has no effect on butyrate metabolism in human colonic epithelial cells
16. Effect of butyrate enemas on the colonic mucosa in distal ulcerative colitis
17. The effect of a pectin-supplemented elemental diet in intestinal adaptation to massive small bowel resection
18. Fatty acid activation
19. Enzymes involved in the formation of amide bonds
20. Isolation from bovine liver mitochondria and characterization of three distinct carboxylic acid:CoA ligases with activity toward xenobiotics
21. Characterization of a renal medium chain acyl-CoA synthetase responsible for glycine conjugation in mouse kidney mitochondria
22. Development of a radiolabeled ATP assay for carboxylic acid:CoA ligases and its use in the characterization of the xenobiotic carboxylic acid:CoA llgases of bovine liver mitochondria
23. Interaction of salicylate and ibuprofen with the carboxylic acid:CoA ligases from bovine liver mitochondria
24. Presence and properties of acyl coenzyme A synthetase for medium-chain fatty acids in rat intestinal mucosa