Resting state functional connectivity in preclinical Alzheimer's disease

Biological Psychiatry

Volumn 74, Issue 5, 2013, Pages 340-347

  Sheline, Yvette I ^a   Raichle, Marcus E ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amyloid; BOLD; default mode network (DMN); fMRI; glycolysis; precuneus

Indexed keywords

ALZHEIMER DISEASE; ANTERIOR CINGULATE; BRAIN METABOLISM; CONNECTOME; DEFAULT MODE NETWORK; DIFFERENTIAL DIAGNOSIS; DORSAL ATTENTION NETWORK; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HUMAN; MILD COGNITIVE IMPAIRMENT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATIVE PHOSPHORYLATION; POSITRON EMISSION TOMOGRAPHY; POSTERIOR CINGULATE; PRIORITY JOURNAL; RESTING STATE NETWORK; RETROSPLENIAL CORTEX; REVIEW;

EID: 84882285123     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2012.11.028     Document Type: Review

References (94)

1. K. Christoff, A.M. Gordon, J. Smallwood, R. Smith, and J.W. Schooler Experience sampling during fMRI reveals default network and executive system contributions to mind wandering Proc Natl Acad Sci U S A 106 2009 8719 8724
2. M.F. Mason, M.I. Norton, J.D. Van Horn, D.M. Wegner, S.T. Grafton, and C.N. Macrae Wandering minds: The default network and stimulus-independent thought Science 315 2007 393 395
3. M. Gruberger, E. Ben-Simon, Y. Levkovitz, A. Zangen, and T. Hendler Towards a neuroscience of mind-wandering Front Hum Neurosci 5 2011 56
4. W. Hasenkamp, C.D. Wilson-Mendenhall, E. Duncan, and L.W. Barsalou Mind wandering and attention during focused meditation: A fine-grained temporal analysis of fluctuating cognitive states Neuroimage 59 2012 750 760
5. A.M. Morcom, and P.C. Fletcher Does the brain have a baseline? Why we should be resisting a rest Neuroimage 37 2007 1073 1082
6. L.J. Larson-Prior, J.M. Zempel, T.S. Nolan, F.W. Prior, A.Z. Snyder, and M.E. Raichle Cortical network functional connectivity in the descent to sleep Proc Natl Acad Sci U S A 106 2009 4489 4494
7. J.L. Vincent, G.H. Patel, M.D. Fox, A.Z. Snyder, J.T. Baker, and D.C. Van Essen Intrinsic functional architecture in the anaesthetized monkey brain Nature 447 2007 83 86
8. B. Biswal, F.Z. Yetkin, V.M. Haughton, and J.S. Hyde Functional connectivity in the motor cortex of resting human brain using echo-planar MRI Magn Reson Med 34 1995 537 541
9. S.J. Li, B. Biswal, Z. Li, R. Risinger, C. Rainey, and J.K. Cho Cocaine administration decreases functional connectivity in human primary visual and motor cortex as detected by functional MRI Magn Reson Med 43 2000 45 51
10. J.S. Damoiseaux, S.A. Rombouts, F. Barkhof, P. Scheltens, C.J. Stam, and S.M. Smith Consistent resting-state networks across healthy subjects Proc Natl Acad Sci U S A 103 2006 13848 13853
11. J.S. Damoiseaux, and M.D. Greicius Greater than the sum of its parts: A review of studies combining structural connectivity and resting-state functional connectivity Brain Struct Funct 213 2009 525 533
12. M.D. Fox, and M.E. Raichle Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging Nat Rev Neurosci 8 2007 700 711
13. G.S. Wig, B.L. Schlaggar, and S.E. Petersen Concepts and principles in the analysis of brain networks Ann N Y Acad Sci 1224 2011 126 146
14. M. D'Esposito, L.Y. Deouell, and A. Gazzaley Alterations in the BOLD fMRI signal with ageing and disease: A challenge for neuroimaging Nat Rev Neurosci 4 2003 863 872
15. M.D. Fox, A.Z. Snyder, J.L. Vincent, M. Corbetta, D.C. Van Essen, and M.E. Raichle The human brain is intrinsically organized into dynamic, anticorrelated functional networks Proc Natl Acad Sci U S A 102 2005 9673 9678
16. R.M. Birn, J.B. Diamond, M.A. Smith, and P.A. Bandettini Separating respiratory-variation-related fluctuations from neuronal-activity-related fluctuations in fMRI Neuroimage 31 2006 1536 1548
17. K. Shmueli, P. van Gelderen, J.A. de Zwart, S.G. Horovitz, M. Fukunaga, and J.M. Jansma Low-frequency fluctuations in the cardiac rate as a source of variance in the resting-state fMRI BOLD signal Neuroimage 38 2007 306 320
18. J.D. Power, K.A. Barnes, A.Z. Snyder, B.L. Schlaggar, and S.E. Petersen Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion Neuroimage 59 2012 2142 2154
19. C.F. Beckmann, M. DeLuca, J.T. Devlin, and S.M. Smith Investigations into resting-state connectivity using independent component analysis Philos T Roy Soc B 360 2005 1001 1013
20. D.A. Fair, A.L. Cohen, N.U. Dosenbach, J.A. Church, F.M. Miezin, and D.M. Barch The maturing architecture of the brain's default network Proc Natl Acad Sci U S A 105 2008 4028 4032
21. B.J. He, A.Z. Snyder, J.L. Vincent, A. Epstein, G.L. Shulman, and M. Corbetta Breakdown of functional connectivity in frontoparietal networks underlies behavioral deficits in spatial neglect Neuron 53 2007 905 918
22. D.A. Fair, B.L. Schlaggar, A.L. Cohen, F.M. Miezin, N.U. Dosenbach, and K.K. Wenger A method for using blocked and event-related fMRI data to study "resting state" functional connectivity Neuroimage 35 2007 396 405
23. M. Brier, J.B. Thomas, A.Z. Snyder, T.L. Benzinger, D. Zhang, and M.E. Raichle Loss of intranetwork and internetwork resting state functional connections with Alzheimer's disease progression J Neurosci 32 2012 8890 8899
24. M.E. Raichle, A.M. MacLeod, A.Z. Snyder, W.J. Powers, D.A. Gusnard, and G.L. Shulman A default mode of brain function Proc Natl Acad Sci U S A 98 2001 676 682
25. M.A. Mintun, G.N. Larossa, Y.I. Sheline, C.S. Dence, S.Y. Lee, and R.H. Mach [11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease Neurology 67 2006 446 452
26. G. Allen, H. Barnard, R. McColl, A.L. Hester, J.A. Fields, and M.F. Weiner Reduced hippocampal functional connectivity in Alzheimer disease Arch Neurol 64 2007 1482 1487
27. M.D. Greicius, G. Srivastava, A.L. Reiss, and V. Menon Default-mode network activity distinguishes Alzheimer's disease from healthy aging: Evidence from functional MRI Proc Natl Acad Sci U S A 101 2004 4637 4642
28. S.J. Li, Z. Li, G. Wu, M.J. Zhang, M. Franczak, and P.G. Antuono Alzheimer disease: Evaluation of a functional MR imaging index as a marker Radiology 225 2002 253 259
29. S. Minoshima, B. Giordani, S. Berent, K.A. Frey, N.L. Foster, and D.E. Kuhl Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease Ann Neurol 42 1997 85 94
30. A. Caroli, A. Prestia, K. Chen, N. Ayutyanont, S.M. Landau, and C.M. Madison Summary metrics to assess Alzheimer disease-related hypometabolic pattern with 18F-FDG PET: Head-to-head comparison J Nucl Med 53 2012 592 600
31. M. Grundman, R.C. Petersen, S.H. Ferris, R.G. Thomas, P.S. Aisen, and D.A. Bennett Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials Arch Neurol 61 2004 59 66
32. J. Bischkopf, A. Busse, and M.C. Angermeyer Mild cognitive impairment - a review of prevalence, incidence and outcome according to current approaches Acta Psychiatr Scand 106 2002 403 414
33. C.Y. Wee, P.T. Yap, D. Zhang, K. Denny, J.N. Browndyke, and G.G. Potter Identification of MCI individuals using structural and functional connectivity networks Neuroimage 59 2012 2045 2056
34. R.A. Sperling, B.C. Dickerson, M. Pihlajamaki, P. Vannini, P.S. LaViolette, and O.V. Vitolo Functional alterations in memory networks in early Alzheimer's disease Neuromolecular Med 12 2010 27 43
35. F. Bai, Z. Zhang, H. Yu, Y. Shi, Y. Yuan, and W. Zhu Default-mode network activity distinguishes amnestic type mild cognitive impairment from healthy aging: A combined structural and resting-state functional MRI study Neurosci Lett 438 2008 111 115
36. A.W. Bero, A.Q. Bauer, F.R. Stewart, B.R. White, J.R. Cirrito, and M.E. Raichle Bidirectional relationship between functional connectivity and amyloid-beta deposition in mouse brain J Neurosci 32 2012 4334 4340
37. F. Agosta, M. Pievani, C. Geroldi, M. Copetti, G.B. Frisoni, and M. Filippi Resting state fMRI in Alzheimer's disease: Beyond the default mode network Neurobiol Aging 33 2011 1564 1578
38. J. Zhou, M.D. Greicius, E.D. Gennatas, M.E. Growdon, J.Y. Jang, and G.D. Rabinovici Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease Brain 133 2010 1352 1367
39. A. Drzezga, T. Grimmer, M. Peller, M. Wermke, H. Siebner, and J.P. Rauschecker Impaired cross-modal inhibition in Alzheimer disease PLoS Med 2 2005 e288
40. C. Lustig, A.Z. Snyder, M. Bhakta, K.C. O'Brien, M. McAvoy, and M.E. Raichle Functional deactivations: Change with age and dementia of the Alzheimer type Proc Natl Acad Sci U S A 100 2003 14504 14509
41. K.A. Celone, V.D. Calhoun, B.C. Dickerson, A. Atri, E.F. Chua, and S.L. Miller Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: An independent component analysis J Neurosci 26 2006 10222 10231
42. A. Hamalainen, M. Pihlajamaki, H. Tanila, T. Hanninen, E. Niskanen, and S. Tervo Increased fMRI responses during encoding in mild cognitive impairment Neurobiol Aging 28 2007 1889 1903
43. R. Heun, K. Freymann, M. Erb, D.T. Leube, F. Jessen, and T.T. Kircher Mild cognitive impairment (MCI) and actual retrieval performance affect cerebral activation in the elderly Neurobiol Aging 28 2007 404 413
44. B.C. Dickerson, and R.A. Sperling Large-scale functional brain network abnormalities in Alzheimer's disease: Insights from functional neuroimaging Behav Neurol 21 2009 63 75
45. M.M. Machulda, H.A. Ward, B. Borowski, J.L. Gunter, R.H. Cha, and P.C. O'Brien Comparison of memory fMRI response among normal, MCI, and Alzheimer's patients Neurology 61 2003 500 506
46. A. Bakker, G.L. Krauss, M.S. Albert, C.L. Speck, L.R. Jones, and C.E. Stark Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment Neuron 74 2012 467 474
47. J.L. Price, and J.C. Morris Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease Ann Neurol 45 1999 358 368
48. J.C. Morris, C.M. Roe, C. Xiong, A.M. Fagan, A.M. Goate, and D.M. Holtzman APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging Ann Neurol 67 2010 122 131
49. H. Braak, and E. Braak Neuropathological staging of Alzheimer-related changes Acta Neuropathol 82 1991 239 259
50. W.E. Klunk, H. Engler, A. Nordberg, Y. Wang, G. Blomqvist, and D.P. Holt Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B Ann Neurol 55 2004 306 319
51. K.A. Johnson, M. Gregas, J.A. Becker, C. Kinnecom, D.H. Salat, and E.K. Moran Imaging of amyloid burden and distribution in cerebral amyloid angiopathy Ann Neurol 62 2007 229 234
52. S.N. Gomperts, D.M. Rentz, E. Moran, J.A. Becker, J.J. Locascio, and W.E. Klunk Imaging amyloid deposition in Lewy body diseases Neurology 71 2008 903 910
53. A.G. Vlassenko, M.A. Mintun, C. Xiong, Y.I. Sheline, A.M. Goate, and T.L. Benzinger Amyloid-beta plaque growth in cognitively normal adults: Longitudinal [11C]Pittsburgh compound B data Ann Neurol 70 2011 857 861
54. J.A. Becker, T. Hedden, J. Carmasin, J. Maye, D.M. Rentz, and D. Putcha Amyloid-beta associated cortical thinning in clinically normal elderly Ann Neurol 69 2011 1032 1042
55. M. Storandt, M.A. Mintun, D. Head, and J.C. Morris Cognitive decline and brain volume loss as signatures of cerebral amyloid-beta peptide deposition identified with Pittsburgh compound B: Cognitive decline associated with Abeta deposition Arch Neurol 66 2009 1476 1481
56. J.C. Morris, C.M. Roe, E.A. Grant, D. Head, M. Storandt, and A.M. Goate Pittsburgh compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer disease Arch Neurol 66 2009 1469 1475
57. T. Jonsson, J.K. Atwal, S. Steinberg, J. Snaedal, P.V. Jonsson, and S. Bjornsson A mutation in APP protects against Alzheimer's disease and age-related cognitive decline Nature 488 2012 96 99
58. R.A. Sperling, P.S. Aisen, L.A. Beckett, D.A. Bennett, S. Craft, and A.M. Fagan Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease Alzheimers Dement 7 2011 280 292
59. C.R. Jack Jr, D.S. Knopman, W.J. Jagust, L.M. Shaw, P.S. Aisen, and M.W. Weiner Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade Lancet Neurol 9 2010 119 128
60. H. Braak, D.R. Thal, E. Ghebremedhin, and K. Del Tredici Stages of the pathologic process in Alzheimer disease: Age categories from 1 to 100 years J Neuropathol Exp Neurol 70 2011 960 969
61. L. Liu, V. Drouet, J.W. Wu, M.P. Witter, S.A. Small, and C. Clelland Trans-synaptic spread of tau pathology in vivo PLoS One 7 2012 e31302
62. C.R. Jack Jr, P. Vemuri, H.J. Wiste, S.D. Weigand, P.S. Aisen, and J.Q. Trojanowski Evidence for ordering of Alzheimer disease biomarkers Arch Neurol 68 2011 1526 1535
63. R.J. Bateman, C. Xiong, T.L. Benzinger, A.M. Fagan, A. Goate, and N.C. Fox Clinical and biomarker changes in dominantly inherited Alzheimer's disease N Engl J Med 367 2012 795 804
64. Y.I. Sheline, J.C. Morris, A.Z. Snyder, J.L. Price, Z. Yan, and G. D'Angelo APOE4 allele disrupts resting state fMRI connectivity in the absence of amyloid plaques or decreased CSF Abeta42 J Neurosci 30 2010 17035 17040
65. E.M. Reiman, K. Chen, G.E. Alexander, R.J. Caselli, D. Bandy, and D. Osborne Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia Proc Natl Acad Sci U S A 101 2004 284 289
66. N. Filippini, B.J. MacIntosh, M.G. Hough, G.M. Goodwin, G.B. Frisoni, and S.M. Smith Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele Proc Natl Acad Sci U S A 106 2009 7209 7214
67. M.M. Machulda, D.T. Jones, P. Vemuri, E. McDade, R. Avula, and S. Przybelski Effect of APOE epsilon4 status on intrinsic network connectivity in cognitively normal elderly subjects Arch Neurol 68 2011 1131 1136
68. Y.I. Sheline, M.E. Raichle, A.Z. Snyder, J.C. Morris, D. Head, and S. Wang Amyloid plaques disrupt resting state default mode network connectivity in cognitively normal elderly Biol Psychiatry 67 2010 584 587
69. T. Hedden, K.R. Van Dijk, J.A. Becker, A. Mehta, R.A. Sperling, and K.A. Johnson Disruption of functional connectivity in clinically normal older adults harboring amyloid burden J Neurosci 29 2009 12686 12694
70. H. Oh, E.C. Mormino, C. Madison, A. Hayenga, A. Smiljic, and W.J. Jagust β-Amyloid affects frontal and posterior brain networks in normal aging Neuroimage 54 2011 1887 1895
71. Y. Kobayashi, and D.G. Amaral Macaque monkey retrosplenial cortex: II. Cortical afferents J Comp Neurol 466 2003 48 79
72. J. Parvizi, G.W. Van Hoesen, J. Buckwalter, and A. Damasio Neural connections of the posteromedial cortex in the macaque Proc Natl Acad Sci U S A 103 2006 1563 1568
73. A. Drzezga, J.A. Becker, K.R. Van Dijk, A. Sreenivasan, T. Talukdar, and C. Sullivan Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden Brain 134 2011 1635 1646
74. E.C. Mormino, A. Smiljic, A.O. Hayenga, S.H. Onami, M.D. Greicius, and G.D. Rabinovici Relationships between β-amyloid and functional connectivity in different components of the default mode network in aging Cereb Cortex 21 2011 2399 2407
75. N.R. Sibson, A. Dhankhar, G.F. Mason, K.L. Behar, D.L. Rothman, and R.G. Shulman In vivo 13C NMR measurements of cerebral glutamine synthesis as evidence for glutamate-glutamine cycling Proc Natl Acad Sci U S A 94 1997 2699 2704
76. R.G. Shulman, D.L. Rothman, K.L. Behar, and F. Hyder Energetic basis of brain activity: Implications for neuroimaging Trends Neurosci 27 2004 489 495
77. J.R. Cirrito, K.A. Yamada, M.B. Finn, R.S. Sloviter, K.R. Bales, and P.C. May Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo Neuron 48 2005 913 922
78. R.L. Buckner, A.Z. Snyder, B.J. Shannon, G. LaRossa, R. Sachs, and A.F. Fotenos Molecular, structural, and functional characterization of Alzheimer's disease: Evidence for a relationship between default activity, amyloid, and memory J Neurosci 25 2005 7709 7717
79. A.G. Vlassenko, S.N. Vaishnavi, L. Couture, D. Sacco, B.J. Shannon, and R.H. Mach Spatial correlation between brain aerobic glycolysis and amyloid-beta (Abeta) deposition Proc Natl Acad Sci U S A 107 2010 17763 17767
80. J.T. Newington, T. Rappon, S. Albers, D.Y. Wong, R.J. Rylett, and R.C. Cumming Overexpression of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase A in nerve cells confers resistance to amyloid β and other toxins by decreasing mitochondrial respiration and ROS production J Biol Chem 287 2012 37245 37258
81. M.G. Vander Heiden, L.C. Cantley, and C.B. Thompson Understanding the Warburg effect: The metabolic requirements of cell proliferation Science 324 2009 1029 1033
82. A.E. Vaughn, and M. Deshmukh Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c Nat Cell Biol 10 2008 1477 1483
83. L. Pellerin, and P.J. Magistretti Glutamate uptake into astrocytes stimulates aerobic glycolysis: A mechanism coupling neuronal activity to glucose utilization Proc Natl Acad Sci U S A 91 1994 10625 10629
84. J.W. Olney Excitotoxicity, apoptosis and neuropsychiatric disorders Curr Opin Pharmacol 3 2003 101 109
85. D. Zhang, Q. Hou, M. Wang, A. Lin, L. Jarzylo, and A. Navis Na,K-ATPase activity regulates AMPA receptor turnover through proteasome-mediated proteolysis J Neurosci 29 2009 4498 4511
86. H. Hsieh, J. Boehm, C. Sato, T. Iwatsubo, T. Tomita, and S. Sisodia AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss Neuron 52 2006 831 843
87. K.A. Brand, and U. Hermfisse Aerobic glycolysis by proliferating cells: A protective strategy against reactive oxygen species FASEB J 11 1997 388 395
88. M.P. Mattson, and T. Magnus Ageing and neuronal vulnerability Nat Rev Neurosci 7 2006 278 294
89. H. Fukui, and C.T. Moraes The mitochondrial impairment, oxidative stress and neurodegeneration connection: Reality or just an attractive hypothesis? Trends Neurosci 31 2008 251 256
90. P.J. Magistretti Neuron-glia metabolic coupling and plasticity J Exp Biol 209 2006 2304 2311
91. I. Allaman, M. Gavillet, M. Belanger, T. Laroche, D. Viertl, and H.A. Lashuel Amyloid-beta aggregates cause alterations of astrocytic metabolic phenotype: Impact on neuronal viability J Neurosci 30 2010 3326 3338
92. J.E. Galvin, J.L. Price, Z. Yan, J.C. Morris, and Y.I. Sheline Resting bold fMRI differentiates dementia with Lewy bodies vs Alzheimer disease Neurology 76 2011 1797 1803
93. W.W. Seeley, V. Menon, A.F. Schatzberg, J. Keller, G.H. Glover, and H. Kenna Dissociable intrinsic connectivity networks for salience processing and executive control J Neurosci 27 2007 2349 2356
94. D. Zhang, and M.E. Raichle Disease and the brain's dark energy Nat Rev Neurol 6 2010 15 28