Loss of intranetwork and internetwork resting state functional connections with Alzheimer's disease progression

Journal of Neuroscience

Volumn 32, Issue 26, 2012, Pages 8890-8899

  Brier, Mathew R ^a   Thomas, Jewell B ^a   Snyder, Abraham Z ^a   Benzinger, Tammie L ^a   Zhang, Dongyang ^a   Raichle, Marcus E ^a   Holtzman, David M ^a   Morris, John C ^a   Ances Dr , Beau M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ALZHEIMER DISEASE; ARTICLE; CROSS-SECTIONAL STUDY; DEMENTIA; DISEASE COURSE; DISEASE SEVERITY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; MAJOR CLINICAL STUDY; MALE; NERVE CELL NETWORK; POSTERIOR CINGULATE; PRIORITY JOURNAL; SEMI STRUCTURED INTERVIEW;

AGED; ALZHEIMER DISEASE; BRAIN; BRAIN MAPPING; COHORT STUDIES; DISEASE PROGRESSION; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; NERVE NET; NEURAL PATHWAYS; OXYGEN; PSYCHIATRIC STATUS RATING SCALES; REST; STATISTICS AS TOPIC;

EID: 84862894679     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5698-11.2012     Document Type: Article

References (74)

1. Agosta F, Pievani M, Geroldi C, Copetti M, Frisoni GB, Filippi M (2011) Resting state fMRI in Alzheimer's disease: beyond the default mode network. Neurobiol Aging. Advance online publication. Retrieved November 2011. doi: 10.1016/j.neurobiolaging.2011.06.007.
2. Alexander GE, Chen K, Pietrini P, Rapoport SI, Reiman EM (2002) Longitudinal PET evaluation of cerebral metabolic decline in dementia: a potential outcome measure in Alzheimer's disease treatment studies. Am J Psychiatry 159:738-745.
3. Beckmann CF, DeLuca M, Devlin JT, Smith SM (2005) Investigations into resting-state connectivity using independent component analysis. Philos Trans R Soc Lond, B, Biol Sci 360:1001-1013.
4. Bero AW, Yan P, Roh JH, Cirrito JR, Stewart FR, Raichle ME, Lee JM, Holtzman DM (2011) Neuronal activity regulates the regional vulnerability to amyloid-β deposition. Nat Neurosci 14:750-756.
5. Biswal B, Yetkin FZ, Haughton VM, Hyde JS (1995) Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med 34:537-541.
6. Blennow K, de Leon MJ, Zetterberg H (2006) Alzheimer's disease. Lancet 368:387-403.
7. Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82:239-259.
8. Büchel C, Josephs O, Rees G, Turner R, Frith CD, Friston KJ (1998) The functional anatomy of attention to visual motion: a functional MRI study. Brain 121:1281-1294.
9. Buckner RL (2004) Memory and executive function in aging and AD: multiple factors that cause decline and reserve factors that compensate. Neuron 44:195-208.
10. Buckner RL, Snyder AZ, Shannon BJ, LaRossa G, Sachs R, Fotenos AF, Sheline YI, Klunk WE, Mathis CA, Morris JC, Mintun MA (2005) Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory. J Neurosci 25:7709-7717.
11. Buckner RL, Andrews-Hanna JR, Schacter DL (2008) The brain's default network: anatomy, function, and relevance to disease. Ann N Y Acad Sci 1124:1-38.
12. Buckner RL, Sepulcre J, Talukdar T, Krienen FM, Liu H, Hedden T, Andrews-Hanna JR, Sperling RA, Johnson KA (2009) Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease. J Neurosci 29:1860-1873.
13. Calhoun VD, Adali T, Pearlson GD, Pekar JJ (2001) A method for making group inferences from functional MRI data using independent component analysis. Hum Brain Mapp 14:140-151.
14. Casey BJ, Cohen JD, O'Craven K, Davidson RJ, Irwin W, Nelson CA, Noll DC, Hu X, Lowe MJ, Rosen BR, Truwitt CL, Turski PA (1998) Reproducibility of fMRI results across four institutions using a spatial working memory task. Neuroimage 8:249-261.
15. Cole MW, Pathak S, Schneider W (2010) Identifying the brain's most globally connected regions. Neuroimage 49:3132-3148.
16. Damoiseaux JS, Rombouts SA, Barkhof F, Scheltens P, Stam CJ, Smith SM, Beckmann CF (2006) Consistent resting-state networks across healthy subjects. Proc Natl Acad Sci U S A 103:13848-13853.
17. de Calignon A, Polydoro M, Suárez-Calvet M, William C, Adamowicz DH, Kopeikina KJ, Pitstick R, Sahara N, Ashe KH, Carlson GA, Spires-Jones TL, Hyman BT (2012) Propagation of tau pathology in a model of early Alzheimer's disease. Neuron 73:685-697.
18. de Zubicaray GI, McMahon K, Wilson SJ, Muthiah S (2001) Brain activity during the encoding, retention, and retrieval of stimulus representations. Learn Mem 8:243-251.
19. Dosenbach NU, Fair DA, Miezin FM, Cohen AL, Wenger KK, Dosenbach RA, Fox MD, Snyder AZ, Vincent JL, Raichle ME, Schlaggar BL, Petersen SE (2007) Distinct brain networks for adaptive and stable task control in humans. Proc Natl Acad Sci U S A 104:11073-11078.
20. Drzezga A, Becker JA, Van Dijk KR, Sreenivasan A, Talukdar T, Sullivan C, Schultz AP, Sepulcre J, Putcha D, Greve D, Johnson KA, Sperling RA (2011) Neuronal dysfunction and disconnection of cortical hubs in nondemented subjects with elevated amyloid burden. Brain 134:1635-1646.
21. Ellermann JM, Siegal JD, Strupp JP, Ebner TJ, Ugurbil K (1998) Activation of visuomotor systems during visually guided movements: a functional MRI study. J Magn Reson 131:272-285.
22. Ewers M, Sperling RA, Klunk WE, Weiner MW, Hampel H (2011) Neuroimaging markers for the prediction and early diagnosis of Alzheimer's disease dementia. Trends Neurosci 34:430-442.
23. Fagan AM, Head D, Shah AR, Marcus D, Mintun M, Morris JC, Holtzman DM (2009) Decreased cerebrospinal fluid Abeta(42) correlates with brain atrophy in cognitively normal elderly. Ann Neurol 65:176-183.
24. Fox MD, Raichle ME (2007) Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat Rev Neurosci 8:700-711.
25. Fox MD, Snyder AZ, Vincent JL, Corbetta M, Van Essen DC, Raichle ME (2005) The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proc Natl Acad Sci U S A 102:9673-9678.
26. Fox MD, Corbetta M, Snyder AZ, Vincent JL, Raichle ME (2006) Spontaneous neuronal activity distinguishes human dorsal and ventral attention systems. Proc Natl Acad Sci U S A 103:10046-10051.
27. Fox MD, Zhang D, Snyder AZ, Raichle ME (2009) The global signal and observed anticorrelated resting state brain networks. J Neurophysiol 101:3270-3283.
28. Greicius MD, Krasnow B, Reiss AL, Menon V (2003) Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci U S A 100:253-258.
29. Greicius MD, Srivastava G, Reiss AL, Menon V (2004) Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc Natl Acad Sci U S A 101:4637-4642.
30. Hagmann P, Cammoun L, Gigandet X, Meuli R, Honey CJ, Wedeen VJ, Sporns O (2008) Mapping the structural core of human cerebral cortex. PLoS Biol 6:e159.
31. Hampson M, Driesen N, Roth JK, Gore JC, Constable RT (2010) Functional connectivity between task-positive and task-negative brain areas and its relation to working memory performance. Magn Reson Imaging 28:1051-1057.
32. Hedden T, Van Dijk KR, Becker JA, Mehta A, Sperling RA, Johnson KA, Buckner RL (2009) Disruption of functional connectivity in clinically normal older adults harboring amyloid burden. J Neurosci 29:12686-12694.
33. Henke K, Mondadori CR, Treyer V, Nitsch RM, Buck A, Hock C (2003) Nonconscious formation and reactivation of semantic associations by way of the medial temporal lobe. Neuropsychologia 41:863-876.
34. Holtzman DM, Morris JC, Goate AM (2011) Alzheimer's disease: the challenge of the second century. Sci Transl Med 3:77sr1.
35. Hyvärinen A (1999) Fast and robust fixed-point algorithms for independent component analysis. IEEE Trans Neural Netw 10:626-634.
36. Johnson SC, Baxter LC, Wilder LS, Pipe JG, Heiserman JE, Prigatano GP (2002) Neural correlates of self-reflection. Brain 125:1808-1814.
37. Jones DT, Machulda MM, Vemuri P, McDade EM, Zeng G, Senjem ML, Gunter JL, Przybelski SA, Avula RT, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr (2011) Age-related changes in the default mode network are more advanced in Alzheimer disease. Neurology 77:1524-1531.
38. Kjaer TW, Nowak M, Lou HC (2002) Reflective self-awareness and conscious states: PET evidence for a common midline parietofrontal core. Neuroimage 17:1080-1086.
39. Macey PM, Macey KE, Kumar R, Harper RM (2004) A method for removal of global effects from fMRI time series. Neuroimage 22:360-366.
40. Mazoyer B, Zago L, Mellet E, Bricogne S, Etard O, Houdé O, Crivello F, Joliot M, Petit L, Tzourio-Mazoyer N (2001) Cortical networks for working memory and executive functions sustain the conscious resting state in man. Brain Res Bull 54:287-298.
41. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease. Neurology 34:939-944.
42. Morris JC (1993) The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology 43:2412-2414.
43. Morris JC, Storandt M, Miller JP, McKeel DW, Price JL, Rubin EH, Berg L (2001) Mild cognitive impairment represents early-stage Alzheimer disease. Arch Neurol 58:397-405.
44. Murphy K, Birn RM, Handwerker DA, Jones TB, Bandettini PA (2009) The impact of global signal regression on resting state correlations: are anticorrelated networks introduced? Neuroimage 44:893-905.
45. Ojemann JG, Buckner RL, Corbetta M, Raichle ME (1997) Imaging studies of memory and attention. Neurosurg Clin N Am 8:307-319.
46. Petrella JR, Sheldon FC, Prince SE, Calhoun VD, Doraiswamy PM (2011) Default mode network connectivity in stable vs progressive mild cognitive impairment. Neurology 76:511-517.
47. Power JD, Barnes KA, Snyder AZ, Schlaggar BL, Petersen SE (2012) Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage 59:2142-2154.
48. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL (2001) A default mode of brain function. Proc Natl Acad Sci U S A 98:676-682.
49. Rombouts SA, Barkhof F, Goekoop R, Stam CJ, Scheltens P (2005) Altered resting state networks in mild cognitive impairment and mild Alzheimer's disease: an fMRI study. Hum Brain Mapp 26:231-239.
50. Sanz-Arigita EJ, Schoonheim MM, Damoiseaux JS, Rombouts SA, Maris E, Barkhof F, Scheltens P, Stam CJ (2010) Loss of'small-world'networks in Alzheimer's disease: graph analysis of FMRI resting-state functional connectivity. PLoS One 5:e13788.
51. Seeley WW, Menon V, Schatzberg AF, Keller J, Glover GH, Kenna H, Reiss AL, Greicius MD (2007) Dissociable intrinsic connectivity networks for salience processing and executive control. J Neurosci 27:2349-2356.
52. Seeley WW, Crawford RK, Zhou J, Miller BL, Greicius MD (2009) Neurodegenerative diseases target large-scale human brain networks. Neuron 62:42-52.
53. Sestieri C, Corbetta M, Romani GL, Shulman GL (2011) Episodic memory retrieval, parietal cortex, and the default mode network: functional and topographic analyses. J Neurosci 31:4407-4420.
54. Shehzad Z, Kelly AM, Reiss PT, Gee DG, Gotimer K, Uddin LQ, Lee SH, Margulies DS, Roy AK, Biswal BB, Petkova E, Castellanos FX, Milham MP (2009) The resting brain: unconstrained yet reliable. Cereb Cortex 19:2209-2229.
55. Sheline YI, Raichle ME, Snyder AZ, Morris JC, Head D, Wang S, Mintun MA (2010) Amyloid plaques disrupt resting state default mode network connectivity in cognitively normal elderly. Biol Psychiatry 67:584-587.
56. Shulman GL, Corbetta M, Buckner RL, Fiez JA, Miezin FM, Raichle ME, Petersen SE (1997) Common blood flow changes across visual tasks. I. increases in subcortical structures and cerebellum but not in nonvisual cortex. J Cogn Neurosci 9:624-647.
57. Shulman GL, Pope DL, Astafiev SV, McAvoy MP, Snyder AZ, Corbetta M (2010) Right hemisphere dominance during spatial selective attention and target detection occurs outside the dorsal frontoparietal network. J Neurosci 30:3640-3651.
58. Smith SM, Fox PT, Miller KL, Glahn DC, Fox PM, Mackay CE, Filippini N, Watkins KE, Toro R, Laird AR, Beckmann CF (2009) Correspondence of the brain's functional architecture during activation and rest. Proc Natl Acad Sci U S A 106:13040-13045.
59. Smyser CD, Inder TE, Shimony JS, Hill JE, Degnan AJ, Snyder AZ, Neil JJ (2010) Longitudinal analysis of neural network development in preterm infants. Cereb Cortex 20:2852-2862.
60. Sorg C, Riedl V, Mühlau M, Calhoun VD, Eichele T, Läer L, Drzezga A, Förstl H, Kurz A, Zimmer C, Wohlschläger AM (2007) Selective changes of resting-state networks in individuals at risk for Alzheimer's disease. Proc Natl Acad Sci U S A 104:18760-18765.
61. Sperling RA, Laviolette PS, O'Keefe K, O'Brien J, Rentz DM, Pihlajamaki M, Marshall G, Hyman BT, Selkoe DJ, Hedden T, Buckner RL, Becker JA, Johnson KA (2009) Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron 63:178-188.
62. Supekar K, Menon V, Rubin D, Musen M, Greicius MD (2008) Network analysis of intrinsic functional brain connectivity in Alzheimer's disease. PLoS Comput Biol 4:e1000100.
63. Sylvester CM, Shulman GL, Jack AI, Corbetta M (2007) Asymmetry of anticipatory activity in visual cortex predicts the locus of attention and perception. J Neurosci 27:14424-14433.
64. Sylvester CM, Shulman GL, Jack AI, Corbetta M (2009) Anticipatory and stimulus-evoked blood oxygenation level-dependent modulations related to spatial attention reflect a common additive signal. J Neurosci 29:10671-10682.
65. Van Dijk KR, Sabuncu MR, Buckner RL (2012) The influence of head motion on intrinsic functional connectivity MRI. Neuroimage 59:431-438.
66. Wang K, Liang M, Wang L, Tian L, Zhang X, Li K, Jiang T (2007) Altered functional connectivity in early Alzheimer's disease: a resting-state fMRI study. Hum Brain Mapp 28:967-978.
67. Weissenbacher A, Kasess C, Gerstl F, Lanzenberger R, Moser E, Windischberger C (2009) Correlations and anticorrelations in resting-state functional connectivity MRI: a quantitative comparison of preprocessing strategies. Neuroimage 47:1408-1416.
68. Zhang D, Raichle ME (2010) Disease and the brain's dark energy. Nat Rev Neurol 6:15-28.
69. Zhang D, Snyder AZ, Shimony JS, Fox MD, Raichle ME (2010) Noninvasive functional and structural connectivity mapping of the human thalamocortical system. Cereb Cortex 20:1187-1194.
70. Zhou J, Greicius MD, Gennatas ED, Growdon ME, Jang JY, Rabinovici GD, Kramer JH, Weiner M, Miller BL, Seeley WW (2010) Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease. Brain 133:1352-1367.
71. Zhou Y, Dougherty JH Jr, Hubner KF, Bai B, Cannon RL, Hutson RK (2008) Abnormal connectivity in the posterior cingulate and hippocampus in early Alzheimer's disease and mild cognitive impairment. Alzheimers Dement 4:265-270.
72. Zielinski BA, Gennatas ED, Zhou J, Seeley WW (2010) Network-level structural covariance in the developing brain. Proc Natl Acad Sci U S A 107:18191-18196.
73. Zuo XN, Di Martino A, Kelly C, Shehzad ZE, Gee DG, Klein DF, Castellanos FX, Biswal BB, Milham MP (2010) The oscillating brain: complex and reliable. Neuroimage 49:1432-1445.
74. Zuo XN, Ehmke R, Mennes M, Imperati D, Castellanos FX, Sporns O, Milham MP (2011) Network centrality in the human functional connectome. Cereb Cortex. Advance online publication. Retrieved March 2010. doi: 1093/cercor/bhr269.