메뉴 건너뛰기




Volumn 425, Issue 17, 2013, Pages 3151-3165

Phosphorylation of the cyclin CaPcl5 modulates both cyclin stability and specific recognition of the substrate

Author keywords

Candida albicans; CDC4; cyclin dependent kinase; Pho85; SCF ubiquitin ligase

Indexed keywords

CYCLINE; UBIQUITIN PROTEIN LIGASE;

EID: 84881668879     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.06.004     Document Type: Article
Times cited : (3)

References (56)
  • 1
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • D.O. Morgan Principles of CDK regulation Nature 374 1995 131 134
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 3
    • 0031844386 scopus 로고    scopus 로고
    • Cyclin partners determine Pho85 protein kinase substrate specificity in vitro and in vivo: Control of glycogen biosynthesis by Pcl8 and Pcl10
    • D. Huang, J. Moffat, W.A. Wilson, L. Moore, C. Cheng, P.J. Roach, and B. Andrews Cyclin partners determine Pho85 protein kinase substrate specificity in vitro and in vivo: control of glycogen biosynthesis by Pcl8 and Pcl10 Mol. Cell. Biol. 18 1998 3289 3299
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3289-3299
    • Huang, D.1    Moffat, J.2    Wilson, W.A.3    Moore, L.4    Cheng, C.5    Roach, P.J.6    Andrews, B.7
  • 4
    • 0032167631 scopus 로고    scopus 로고
    • Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A
    • B.A. Schulman, D.L. Lindstrom, and E. Harlow Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A Proc. Natl Acad. Sci. USA 95 1998 10453 10458
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 10453-10458
    • Schulman, B.A.1    Lindstrom, D.L.2    Harlow, E.3
  • 5
    • 0032863161 scopus 로고    scopus 로고
    • Substrate targeting of the yeast cyclin-dependent kinase Pho85p by the cyclin Pcl10p
    • W.A. Wilson, A.M. Mahrenholz, and P.J. Roach Substrate targeting of the yeast cyclin-dependent kinase Pho85p by the cyclin Pcl10p Mol. Cell. Biol. 19 1999 7020 7030
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7020-7030
    • Wilson, W.A.1    Mahrenholz, A.M.2    Roach, P.J.3
  • 6
    • 0034987247 scopus 로고    scopus 로고
    • Cyclin specificity: How many wheels do you need on a unicycle?
    • M.E. Miller, and F.R. Cross Cyclin specificity: how many wheels do you need on a unicycle? J. Cell Sci. 114 2001 1811 1820
    • (2001) J. Cell Sci. , vol.114 , pp. 1811-1820
    • Miller, M.E.1    Cross, F.R.2
  • 8
    • 0033428894 scopus 로고    scopus 로고
    • Mammalian Cdk5 is a functional homologue of the budding yeast Pho85 cyclin-dependent protein kinase
    • D. Huang, G. Patrick, J. Moffat, L.H. Tsai, and B. Andrews Mammalian Cdk5 is a functional homologue of the budding yeast Pho85 cyclin-dependent protein kinase Proc. Natl Acad. Sci. USA 96 1999 14445 14450
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 14445-14450
    • Huang, D.1    Patrick, G.2    Moffat, J.3    Tsai, L.H.4    Andrews, B.5
  • 9
    • 0033607545 scopus 로고    scopus 로고
    • Mouse cyclin-dependent kinase (Cdk) 5 is a functional homologue of a yeast Cdk, Pho85 kinase
    • M. Nishizawa, Y. Kanaya, and E.A. Toh Mouse cyclin-dependent kinase (Cdk) 5 is a functional homologue of a yeast Cdk, Pho85 kinase J. Biol. Chem. 274 1999 33859 33862
    • (1999) J. Biol. Chem. , vol.274 , pp. 33859-33862
    • Nishizawa, M.1    Kanaya, Y.2    Toh, E.A.3
  • 10
    • 0028207513 scopus 로고
    • Phosphorylation of the transcription factor PHO4 by a cyclin-CDK complex, PHO80-PHO85
    • A. Kaffman, I. Herskowitz, R. Tjian, and E.K. O'Shea Phosphorylation of the transcription factor PHO4 by a cyclin-CDK complex, PHO80-PHO85 Science 263 1994 1153 1156
    • (1994) Science , vol.263 , pp. 1153-1156
    • Kaffman, A.1    Herskowitz, I.2    Tjian, R.3    O'Shea, E.K.4
  • 11
    • 0028027464 scopus 로고
    • The transcription factor, the Cdk, its cyclin and their regulator: Directing the transcriptional response to a nutritional signal
    • K. Hirst, F. Fisher, P.C. McAndrew, and C.R. Goding The transcription factor, the Cdk, its cyclin and their regulator: directing the transcriptional response to a nutritional signal EMBO J. 13 1994 5410 5420
    • (1994) EMBO J. , vol.13 , pp. 5410-5420
    • Hirst, K.1    Fisher, F.2    McAndrew, P.C.3    Goding, C.R.4
  • 12
    • 67749114241 scopus 로고    scopus 로고
    • Regulation of cell polarity through phosphorylation of Bni4 by Pho85 G1 cyclin-dependent kinases in Saccharomyces cerevisiae
    • J. Zou, H. Friesen, J. Larson, D. Huang, M. Cox, K. Tatchell, and B. Andrews Regulation of cell polarity through phosphorylation of Bni4 by Pho85 G1 cyclin-dependent kinases in Saccharomyces cerevisiae Mol. Biol. Cell 20 2009 3239 3250
    • (2009) Mol. Biol. Cell , vol.20 , pp. 3239-3250
    • Zou, J.1    Friesen, H.2    Larson, J.3    Huang, D.4    Cox, M.5    Tatchell, K.6    Andrews, B.7
  • 13
    • 0034017609 scopus 로고    scopus 로고
    • Degradation of the transcription factor Gcn4 requires the kinase Pho85 and the SCF(CDC4) ubiquitin-ligase complex
    • A. Meimoun, T. Holtzman, Z. Weissman, H.J. McBride, D.J. Stillman, G.R. Fink, and D. Kornitzer Degradation of the transcription factor Gcn4 requires the kinase Pho85 and the SCF(CDC4) ubiquitin-ligase complex Mol. Biol. Cell 11 2000 915 927
    • (2000) Mol. Biol. Cell , vol.11 , pp. 915-927
    • Meimoun, A.1    Holtzman, T.2    Weissman, Z.3    McBride, H.J.4    Stillman, D.J.5    Fink, G.R.6    Kornitzer, D.7
  • 14
    • 0036311160 scopus 로고    scopus 로고
    • Regulation of the transcription factor Gcn4 by Pho85 cyclin PCL5
    • R. Shemer, A. Meimoun, T. Holtzman, and D. Kornitzer Regulation of the transcription factor Gcn4 by Pho85 cyclin PCL5 Mol. Cell. Biol. 22 2002 5395 5404
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5395-5404
    • Shemer, R.1    Meimoun, A.2    Holtzman, T.3    Kornitzer, D.4
  • 15
    • 0028607143 scopus 로고
    • Regulated degradation of the transcription factor Gcn4
    • D. Kornitzer, B. Raboy, R.G. Kulka, and G.R. Fink Regulated degradation of the transcription factor Gcn4 EMBO J. 13 1994 6021 6030
    • (1994) EMBO J. , vol.13 , pp. 6021-6030
    • Kornitzer, D.1    Raboy, B.2    Kulka, R.G.3    Fink, G.R.4
  • 16
  • 17
    • 55849153104 scopus 로고    scopus 로고
    • Autophosphorylation-induced degradation of the Pho85 cyclin Pcl5 is essential for response to amino acid limitation
    • S. Aviram, E. Simon, T. Gildor, F. Glaser, and D. Kornitzer Autophosphorylation-induced degradation of the Pho85 cyclin Pcl5 is essential for response to amino acid limitation Mol. Cell. Biol. 28 2008 6858 6869
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 6858-6869
    • Aviram, S.1    Simon, E.2    Gildor, T.3    Glaser, F.4    Kornitzer, D.5
  • 20
    • 0029665852 scopus 로고    scopus 로고
    • Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex
    • A.A. Russo, P.D. Jeffrey, A.K. Patten, J. Massague, and N.P. Pavletich Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex Nature 382 1996 325 331
    • (1996) Nature , vol.382 , pp. 325-331
    • Russo, A.A.1    Jeffrey, P.D.2    Patten, A.K.3    Massague, J.4    Pavletich, N.P.5
  • 21
    • 0033224309 scopus 로고    scopus 로고
    • The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases
    • N.R. Brown, M.E. Noble, J.A. Endicott, and L.N. Johnson The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases Nat. Cell Biol. 1 1999 438 443
    • (1999) Nat. Cell Biol. , vol.1 , pp. 438-443
    • Brown, N.R.1    Noble, M.E.2    Endicott, J.A.3    Johnson, L.N.4
  • 24
    • 0034124959 scopus 로고    scopus 로고
    • Conservation and function of a potential substrate-binding domain in the yeast Clb5 B-type cyclin
    • F.R. Cross, and M.D. Jacobson Conservation and function of a potential substrate-binding domain in the yeast Clb5 B-type cyclin Mol. Cell. Biol. 20 2000 4782 4790
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 4782-4790
    • Cross, F.R.1    Jacobson, M.D.2
  • 25
    • 14544270984 scopus 로고    scopus 로고
    • Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates
    • M. Loog, and D.O. Morgan Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates Nature 434 2005 104 108
    • (2005) Nature , vol.434 , pp. 104-108
    • Loog, M.1    Morgan, D.O.2
  • 26
    • 2442528837 scopus 로고    scopus 로고
    • Interaction of the S-phase cyclin Clb5 with an "rXL" docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch
    • G.M. Wilmes, V. Archambault, R.J. Austin, M.D. Jacobson, S.P. Bell, and F.R. Cross Interaction of the S-phase cyclin Clb5 with an "RXL" docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch Genes Dev. 18 2004 981 991
    • (2004) Genes Dev. , vol.18 , pp. 981-991
    • Wilmes, G.M.1    Archambault, V.2    Austin, R.J.3    Jacobson, M.D.4    Bell, S.P.5    Cross, F.R.6
  • 27
    • 36248959857 scopus 로고    scopus 로고
    • Structure of the Pho85-Pho80 CDK-cyclin complex of the phosphate-responsive signal transduction pathway
    • K. Huang, I. Ferrin-O'Connell, W. Zhang, G.A. Leonard, E.K. O'Shea, and F.A. Quiocho Structure of the Pho85-Pho80 CDK-cyclin complex of the phosphate-responsive signal transduction pathway Mol. Cell 28 2007 614 623
    • (2007) Mol. Cell , vol.28 , pp. 614-623
    • Huang, K.1    Ferrin-O'Connell, I.2    Zhang, W.3    Leonard, G.A.4    O'Shea, E.K.5    Quiocho, F.A.6
  • 28
    • 9644273891 scopus 로고    scopus 로고
    • A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin
    • A.R. Willems, M. Schwab, and M. Tyers A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin Biochim. Biophys. Acta 1695 2004 133 170
    • (2004) Biochim. Biophys. Acta , vol.1695 , pp. 133-170
    • Willems, A.R.1    Schwab, M.2    Tyers, M.3
  • 29
    • 84855243126 scopus 로고    scopus 로고
    • Neddylation and CAND1 independently stimulate SCF ubiquitin ligase activity in Candida albicans
    • N. Sela, A. Atir-Lande, and D. Kornitzer Neddylation and CAND1 independently stimulate SCF ubiquitin ligase activity in Candida albicans Eukaryot. Cell 11 2012 42 52
    • (2012) Eukaryot. Cell , vol.11 , pp. 42-52
    • Sela, N.1    Atir-Lande, A.2    Kornitzer, D.3
  • 30
    • 19644382950 scopus 로고    scopus 로고
    • Role for the SCF(CDC4) ubiquitin ligase in Candida albicans morphogenesis
    • A. Atir-Lande, T. Gildor, and D. Kornitzer Role for the SCF(CDC4) ubiquitin ligase in Candida albicans morphogenesis Mol. Biol. Cell 16 2005 2772 2785
    • (2005) Mol. Biol. Cell , vol.16 , pp. 2772-2785
    • Atir-Lande, A.1    Gildor, T.2    Kornitzer, D.3
  • 31
    • 17044429330 scopus 로고    scopus 로고
    • A roller coaster ride with the mitotic cyclins
    • T.K. Fung, and R.Y. Poon A roller coaster ride with the mitotic cyclins Semin. Cell Dev. Biol. 16 2005 335 342
    • (2005) Semin. Cell Dev. Biol. , vol.16 , pp. 335-342
    • Fung, T.K.1    Poon, R.Y.2
  • 33
    • 0032802393 scopus 로고    scopus 로고
    • Cyclin-dependent kinases: Inhibition and substrate recognition
    • J.A. Endicott, M.E. Noble, and J.A. Tucker Cyclin-dependent kinases: inhibition and substrate recognition Curr. Opin. Struct. Biol. 9 1999 738 744
    • (1999) Curr. Opin. Struct. Biol. , vol.9 , pp. 738-744
    • Endicott, J.A.1    Noble, M.E.2    Tucker, J.A.3
  • 34
    • 0344255680 scopus 로고    scopus 로고
    • A distal, high-affinity binding site on the cyclin-CDK substrate Pho4 is important for its phosphorylation and regulation
    • M. Byrne, N. Miller, M. Springer, and E.K. O'Shea A distal, high-affinity binding site on the cyclin-CDK substrate Pho4 is important for its phosphorylation and regulation J. Mol. Biol. 335 2004 57 70
    • (2004) J. Mol. Biol. , vol.335 , pp. 57-70
    • Byrne, M.1    Miller, N.2    Springer, M.3    O'Shea, E.K.4
  • 36
    • 0347380122 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 and neuronal migration in the neocortex
    • A. Gupta, and L.H. Tsai Cyclin-dependent kinase 5 and neuronal migration in the neocortex Neurosignals 12 2003 173 179
    • (2003) Neurosignals , vol.12 , pp. 173-179
    • Gupta, A.1    Tsai, L.H.2
  • 37
    • 0027757042 scopus 로고
    • Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5
    • K. Baumann, E.M. Mandelkow, J. Biernat, H. Piwnica-Worms, and E. Mandelkow Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5 FEBS Lett. 336 1993 417 424
    • (1993) FEBS Lett. , vol.336 , pp. 417-424
    • Baumann, K.1    Mandelkow, E.M.2    Biernat, J.3    Piwnica-Worms, H.4    Mandelkow, E.5
  • 38
    • 0033540078 scopus 로고    scopus 로고
    • Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons
    • J.A. Bibb, G.L. Snyder, A. Nishi, Z. Yan, L. Meijer, and A.A. Fienberg Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons Nature 402 1999 669 671
    • (1999) Nature , vol.402 , pp. 669-671
    • Bibb, J.A.1    Snyder, G.L.2    Nishi, A.3    Yan, Z.4    Meijer, L.5    Fienberg, A.A.6
  • 39
    • 0742270492 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 phosphorylates the N-terminal domain of the postsynaptic density protein PSD-95 in neurons
    • M.A. Morabito, M. Sheng, and L.H. Tsai Cyclin-dependent kinase 5 phosphorylates the N-terminal domain of the postsynaptic density protein PSD-95 in neurons J. Neurosci. 24 2004 865 876
    • (2004) J. Neurosci. , vol.24 , pp. 865-876
    • Morabito, M.A.1    Sheng, M.2    Tsai, L.H.3
  • 40
    • 0348010575 scopus 로고    scopus 로고
    • Cdk5: A new player at synapses
    • K. Cheng, and N.Y. Ip Cdk5: a new player at synapses Neurosignals 12 2003 180 190
    • (2003) Neurosignals , vol.12 , pp. 180-190
    • Cheng, K.1    Ip, N.Y.2
  • 42
    • 0027978170 scopus 로고
    • P35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5
    • L.H. Tsai, I. Delalle, V.S. Caviness Jr., T. Chae, and E. Harlow p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5 Nature 371 1994 419 423
    • (1994) Nature , vol.371 , pp. 419-423
    • Tsai, L.H.1    Delalle, I.2    Caviness, Jr.V.S.3    Chae, T.4    Harlow, E.5
  • 45
    • 4444262625 scopus 로고    scopus 로고
    • Cdk5 deregulation in the pathogenesis of Alzheimer's disease
    • J.C. Cruz, and L.H. Tsai Cdk5 deregulation in the pathogenesis of Alzheimer's disease Trends Mol. Med. 10 2004 452 458
    • (2004) Trends Mol. Med. , vol.10 , pp. 452-458
    • Cruz, J.C.1    Tsai, L.H.2
  • 46
    • 2942572871 scopus 로고    scopus 로고
    • A Jekyll and Hyde kinase: Roles for Cdk5 in brain development and disease
    • J.C. Cruz, and L.H. Tsai A Jekyll and Hyde kinase: roles for Cdk5 in brain development and disease Curr. Opin. Neurobiol. 14 2004 390 394
    • (2004) Curr. Opin. Neurobiol. , vol.14 , pp. 390-394
    • Cruz, J.C.1    Tsai, L.H.2
  • 47
    • 0346119136 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 in amyotrophic lateral sclerosis
    • M.D. Nguyen, and J.P. Julien Cyclin-dependent kinase 5 in amyotrophic lateral sclerosis Neurosignals 12 2003 215 220
    • (2003) Neurosignals , vol.12 , pp. 215-220
    • Nguyen, M.D.1    Julien, J.P.2
  • 48
    • 0033540060 scopus 로고    scopus 로고
    • Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
    • G.N. Patrick, L. Zukerberg, M. Nikolic, S. de la Monte, P. Dikkes, and L.H. Tsai Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration Nature 402 1999 615 622
    • (1999) Nature , vol.402 , pp. 615-622
    • Patrick, G.N.1    Zukerberg, L.2    Nikolic, M.3    De La Monte, S.4    Dikkes, P.5    Tsai, L.H.6
  • 49
    • 0348010572 scopus 로고    scopus 로고
    • The regulation of cyclin-dependent kinase 5 activity through the metabolism of p35 or p39 Cdk5 activator
    • S. Hisanaga, and T. Saito The regulation of cyclin-dependent kinase 5 activity through the metabolism of p35 or p39 Cdk5 activator Neurosignals 12 2003 221 229
    • (2003) Neurosignals , vol.12 , pp. 221-229
    • Hisanaga, S.1    Saito, T.2
  • 50
    • 0027192868 scopus 로고
    • Isogenic strain construction and gene mapping in Candida albicans
    • W.A. Fonzi, and M.Y. Irwin Isogenic strain construction and gene mapping in Candida albicans Genetics 134 1993 717 728
    • (1993) Genetics , vol.134 , pp. 717-728
    • Fonzi, W.A.1    Irwin, M.Y.2
  • 51
    • 0034351185 scopus 로고    scopus 로고
    • Tetracycline-regulatable system to tightly control gene expression in the pathogenic fungus Candida albicans
    • H. Nakayama, T. Mio, S. Nagahashi, M. Kokado, M. Arisawa, and Y. Aoki Tetracycline-regulatable system to tightly control gene expression in the pathogenic fungus Candida albicans Infect. Immun. 68 2000 6712 6719
    • (2000) Infect. Immun. , vol.68 , pp. 6712-6719
    • Nakayama, H.1    Mio, T.2    Nagahashi, S.3    Kokado, M.4    Arisawa, M.5    Aoki, Y.6
  • 52
    • 13844316993 scopus 로고    scopus 로고
    • Strains and strategies for large-scale gene deletion studies of the diploid human fungal pathogen Candida albicans
    • S.M. Noble, and A.D. Johnson Strains and strategies for large-scale gene deletion studies of the diploid human fungal pathogen Candida albicans Eukaryot. Cell 4 2005 298 309
    • (2005) Eukaryot. Cell , vol.4 , pp. 298-309
    • Noble, S.M.1    Johnson, A.D.2
  • 53
    • 0032692954 scopus 로고    scopus 로고
    • Ras signaling is required for serum-induced hyphal differentiation in Candida albicans
    • Q. Feng, E. Summers, B. Guo, and G. Fink Ras signaling is required for serum-induced hyphal differentiation in Candida albicans J. Bacteriol. 181 1999 6339 6346
    • (1999) J. Bacteriol. , vol.181 , pp. 6339-6346
    • Feng, Q.1    Summers, E.2    Guo, B.3    Fink, G.4
  • 54
    • 0031671237 scopus 로고    scopus 로고
    • Phosphorylation of sic1, a cyclin-dependent kinase (Cdk) inhibitor, by Cdk including Pho85 kinase is required for its prompt degradation
    • M. Nishizawa, M. Kawasumi, M. Fujino, and A. Toh-e Phosphorylation of sic1, a cyclin-dependent kinase (Cdk) inhibitor, by Cdk including Pho85 kinase is required for its prompt degradation Mol. Biol. Cell 9 1998 2393 2405
    • (1998) Mol. Biol. Cell , vol.9 , pp. 2393-2405
    • Nishizawa, M.1    Kawasumi, M.2    Fujino, M.3    Toh-E, A.4
  • 55
    • 0028586017 scopus 로고
    • Regulatable promoters of Saccharomyces cerevisiae: Comparison of transcriptional activity and their use for heterologous expression
    • D. Mumberg, R. Muller, and M. Funk Regulatable promoters of Saccharomyces cerevisiae: comparison of transcriptional activity and their use for heterologous expression Nucleic Acids Res. 22 1994 5767 5768
    • (1994) Nucleic Acids Res. , vol.22 , pp. 5767-5768
    • Mumberg, D.1    Muller, R.2    Funk, M.3
  • 56
    • 0036275401 scopus 로고    scopus 로고
    • Monitoring protein degradation
    • D. Kornitzer Monitoring protein degradation Methods Enzymol. 351 2002 639 647
    • (2002) Methods Enzymol. , vol.351 , pp. 639-647
    • Kornitzer, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.