Role of hydroxamate-based histone deacetylase inhibitors (Hb-HDACIs) in the treatment of solid malignancies

Cancers

Volumn 5, Issue 3, 2013, Pages 919-942

  Grassadonia, Antonino ^a   Cioffi, Pasquale ^b   Simiele, Felice ^b   Iezzi, Laura ^b   Zilli, Marinella ^b   Natoli, Clara ^a  

^a UNIVERSITY OF CHIETI   (Italy)

^b 'SS Annunziata' Hospital   (Italy)

Author keywords

Abexinostat; Belinostat; Histone deacetylase inhibitors; Hydroxamate based histone deacetylase inhibitors; Panobinostat; Pracinostat; Resminostat; Vorinostat

Indexed keywords

ABEXINOSTAT; AMIDOHYDROLASE INHIBITOR; BELINOSTAT; BORTEZOMIB; CARBOPLATIN; CARFILZOMIB; CHR 3996; DACINOSTAT; DOCETAXEL; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; GIVINOSTAT; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; NAVELBINE; OXALIPLATIN; PACLITAXEL; PANOBINOSTAT; PLACEBO; PRACINOSTAT; QUISINOSTAT; RESMINOSTAT; ROMIDEPSIN; SALINOSPORAMIDE A; SB 939; TAMOXIFEN; TEFINOSTAT; TRICHOSTATIN A; UNCLASSIFIED DRUG; UNINDEXED DRUG; VORINOSTAT;

ADVANCED CANCER; ANEMIA; ANOREXIA; ANTINEOPLASTIC ACTIVITY; BONE MARROW SUPPRESSION; BRAIN CANCER; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER COMBINATION CHEMOTHERAPY; CASTRATION RESISTANT PROSTATE CANCER; CHEMOTHERAPY INDUCED NAUSEA AND VOMITING; COLON CANCER; COLORECTAL CANCER; CREATININE BLOOD LEVEL; CUTANEOUS T CELL LYMPHOMA; DEHYDRATION; DIARRHEA; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG HALF LIFE; DRUG MECHANISM; DRUG POTENTIATION; DRUG SAFETY; DRUG STRUCTURE; DRUG TOLERABILITY; FATIGUE; GALLBLADDER CARCINOMA; GASTROINTESTINAL DISEASE; GLIOBLASTOMA; GLIOMA; HEAD AND NECK CANCER; HEART ATRIUM FIBRILLATION; HEMATOLOGIC DISEASE; HODGKIN DISEASE; HUMAN; HYPERGLYCEMIA; HYPONATREMIA; KIDNEY CARCINOMA; LETHARGY; LIVER CELL CARCINOMA; LUNG CANCER; LUNG NON SMALL CELL CANCER; MALIGNANT PERIPHERAL NERVE SHEATH TUMOR; MELANOMA; METASTASIS; MUCOSA INFLAMMATION; MULTIPLE CYCLE TREATMENT; MYALGIA; NAUSEA; NEUTROPENIA; NONHUMAN; OVARY CANCER; OVARY TUMOR; PANCREAS CANCER; PANCREAS CARCINOMA; PERIPHERAL T CELL LYMPHOMA; PERITONEUM CANCER; PLEURA MESOTHELIOMA; PROSTATE CANCER; RECOMMENDED DRUG DOSE; REVIEW; SENSORY NEUROPATHY; SIDE EFFECT; SOFT TISSUE SARCOMA; SOLID TUMOR; STRUCTURE ACTIVITY RELATION; THROMBOCYTOPENIA; THROMBOEMBOLISM; THYMOMA; THYROID CANCER; UTERINE TUBE CARCINOMA; VOMITING;

EID: 84881570005     PISSN: None     EISSN: 20726694     Source Type: Journal    
DOI: 10.3390/cancers5030919     Document Type: Review

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