Benzo[b]thiophene-based histone deacetylase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 16, 2007, Pages 4562-4567

  Witter, David J ^a   Belvedere, Sandro ^b   Chen, Liqiang ^c   Secrist, J Paul ^a   Mosley, Ralph T ^a   Miller, Thomas A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b ARMGO Pharma Inc   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Anticancer drug; Benzo b thiophene; HDAC; HDAC inhibitor; Histone deacetylase inhibitor; Hydroxamic acids; SAHA

Indexed keywords

BENZOTHIOPHENE; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID DERIVATIVE; RALOXIFENE; ZILEUTON;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DETERMINATION; DRUG IDENTIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; ERYTHROLEUKEMIA; NONHUMAN; STOICHIOMETRY;

COMBINATORIAL CHEMISTRY TECHNIQUES; COMPUTER SIMULATION; HISTONE DEACETYLASES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

MURINAE;

EID: 34447309733     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.05.091     Document Type: Article

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