Knockdown of both FoxO1 and C/EBPβ promotes adipogenesis in porcine preadipocytes through feedback regulation

Cell Biology International

Volumn 37, Issue 9, 2013, Pages 905-916

  Yan, Xiong ^a   Weijun, Pang ^a   Ning, Wei ^a   Yu, Wang ^a   Wenkai, Ren ^b   Gongshe, Yang ^a  

^a NORTHWEST A F UNIVERSITY   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Adipogenesis; C EBPb; FoxO1; Pig; Preadipocyte

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; CCAAT ENHANCER BINDING PROTEIN BETA; LENTIVIRUS VECTOR; MESSENGER RNA; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR FKHR;

ADIPOGENESIS; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; FEEDBACK SYSTEM; IMMUNOPRECIPITATION; LIPID STORAGE; NONHUMAN; PROADIPOCYTE; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SWINE;

LENTIVIRUS; SUIDAE; SUS;

EID: 84881557834     PISSN: 10656995     EISSN: 10958355     Source Type: Journal    
DOI: 10.1002/cbin.10115     Document Type: Article

References (43)

1. Accili D, Arden KC (2004) FoxOs at the crossroads of cellular metabolism, differentiation, and transformation. Cell 117: 421-6.
2. Arden KC (2008) FOXO animal models reveal a variety of diverse roles for FOXO transcription factors. Oncogene 27: 2345-50.
3. Armoni M, Harel C, Karni S, Chen H, Bar-Yoseph F,Ver MR, Quon MJ, Karnieli E (2006) FOXO1 represses peroxisome prolifer-ator-activated receptor-gamma1 and -gamma2 gene promoters in primary adipocytes. A novel paradigm to increase insulin sensitivity. J Biol Chem 281: 19881-91.
4. Bai L, Pang WJ, Yang YJ, Yang GS (2008) Modulation of Sirt1 by resveratrol and nicotinamide alters proliferation and differentiation of pig preadipocytes. Mol Cell Biochem 307: 129-40.
5. Bellinger DA, Merricks EP, Nichols TC (2006) Swine models of type 2 diabetes mellitus: insulin resistance, glucose tolerance, and cardiovascular complications. ILAR J 47: 243-58.
6. Brambilla G, Cantafora A (2004) Metabolic and cardiovascular disorders in highly inbred lines for intensive pig farming: how animal welfare evaluation could improve the basic knowledge of human obesity. Ann Ist Super Sanita 40: 241-4.
7. Brummelkamp TR, Bernards R, Agami R (2002) A system for stable expression of short interfering RNAs in mammalian cells. Science 296: 550-3.
8. Camp HS, Ren D, Leff T (2002) Adipogenesis and fat-cell function in obesity and diabetes. Trends Mol Med 8: 442-7.
9. Chakrabarti P, Kandror KV (2009) FoxO1 controls insulin-dependent adipose triglyceride lipase (ATGL) expression and lipolysis in adipocytes. J Biol Chem 284: 13296-300.
10. Chakrabarti P, English T, Karki S, Qiang L, Chakrabarti P, English T, Karki S, Qiang L, Tao R, Kim J, Luo Z, Farmer SR, Kandror KV (2011) SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL. Journal of lipid research 52: 1693-701.
11. Christian M, Zhang X, Schneider-Merck T, Unterman TG, Gellersen B, White JO, Brosens JJ (2002) Cyclic AMP-induced forkhead transcription factor, FKHR, cooperates with CCAAT/ enhancer-binding protein beta in differentiating human endo-metrial stromal cells. J Biol Chem 277: 20825-32.
12. Ding ST, McNeel RL, Mersmann HJ (1999) Expression of porcine adipocyte transcripts tissue distribution and differentiation in vitro and in vivo. Compar Biochem Physiol Part B 123: 307-18.
13. Farmer SR (2006) Transcriptional control of adipocyte formation. Cell Metab 4: 263-73.
14. Feve B (2005) Adipogenesis: cellular and molecular aspects. Best Prac Res Clin Endocrinol Metab 19: 483-99.
15. Fu Y, Luo N, Klein RL, Garvey WT (2005) Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation. J Lipid Res 46: 1369-79.
16. Fujimori K, Amano F (2011) Forkhead transcription factor Foxa1 is a novel target gene of C/EBPbeta and suppresses the early phase of adipogenesis. Gene 473: 150-6.
17. Gomis RR, Alarcón C, He W, Wang Q, Seoane J, Lash A, Massague J (2006) A FoxO-Smad synexpression group in human kerati-nocytes. Proc Natl Acad Sci USA 103: 12747-52.
18. Hamm JK, Park BH, Farmer SR (2001) A role for C/EBPbeta in regulating peroxisome proliferator-activated receptor gamma activity during adipogenesis in 3T3-L1 preadipocytes. J Biol Chem 276: 18464-71.
19. Hausman GJ (2000) The influence of dexamethasone and insulin on expression of CCAAT/enhancer binding protein isoforms during preadipocyte differentiation in porcine stromal-vascular cell cultures: evidence for very early expression of C/EBPalpha. J Anim Sci 78: 1227-35.
20. Hausman GJ (2003) Dexamethasone induced preadipocyte recruitment and expression of CCAAT/enhancing binding protein a and peroxisome proliferator activated receptor-g proteins in porcine stromal-vascular (S-V) cell cultures obtained before and after the onset of fetal adipogenesis. Gen Compar Endocrinol 133: 61-70.
21. Ito Y, Daitoku H, Fukamizu A (2009) Foxo1 increases pro-inflammatory gene expression by inducing C/EBPb in TNF-a-treated adipocytes. Biochem Biophys Res Commun 378: 290-5.
22. Jordan M, Schallhorn A, Wurm FM (1996) Transfecting mammalian cells: optimization of critical parameters affecting calcium-phosphate precipitate formation. Nucleic Acids Res 24: 596-601.
23. Kim JJ, Li P, Huntley J, Chang JP, Arden KC, Olefsky JM (2009) FoxO1 haploinsufficiency protects against high-fat diet-induced insulin resistance with enhanced peroxisome proliferator-activated receptor gamma activation in adipose tissue. Diabetes 58: 1275-82.
24. Koutnikova H, Auwerx J (2001) Regulation of adipocyte differentiation. Ann Med 33: 556-61.
25. Larsen MO, Rolin B (2004) Use of the Gottingen minipig as a model of diabetes, with special focus on type 1 diabetes research. ILAR J 45: 303-13.
26. Lee K, Hausman GJ, Dean RG (1998) Expression of C/EBPa b and d in fetal and postnatal subcutaneous adipose tissue. Mol Cell Biochem 178: 269-74.
27. Lee NS, Dohjima T, Bauer G, Li H, Li MJ, Ehsani A, Salvaterra P, Rossi J (2002) Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat Biotechnol 20: 500-5.
28. Lefterova MI, Lazar MA (2009) New developments in adipogenesis. Trends Endocrinol Metab 20: 107-14.
29. Lowe CE, O'Rahilly S, Rochford JJ (2011) Adipogenesis at a glance.J Cell Sci 124: 2681-6.
30. McNeel RL, Ding ST, Smith EOB, Mersmann HJ (2000) Expression of porcine adipocyte transcripts during differentiation in vitro and in vivo. Compar Bio hem Physiol Part B 126: 291-302.
31. Nakae J, Kitamura T, Kitamura Y, Biggs WH III, Arden KC, Accili D (2003) The forkhead transcription factor Foxo1 regulates adipocyte differentiation. Dev Cell 4: 119-29. Pang WJ, Yu TY, Bai L, Yang YJ, Yang GS (2008) Tissue expression of porcine FoxO1 and it negative regulation during primary differentiation. Mol Biol Rep 36: 165-76. Poulos SP, Dodson MV, Hausman GJ (2010) Cell line models for differentiation: preadipocytes and adipocytes. Exp Biol Med (maywood) 235: 1185-93.
32. Rajala MW, Scherer PE (2003) Minireview: the adipocyte-at the crossroads of energy homeostasis, inflammation, and atherosclerosis. Endocrinology 144: 3765-73.
33. Rangwala SM, Lazar MA (2000) Transcriptional control of adipogenesis. Annu Rev Nutr 20: 535-9. Rosen ED, MacDougald OA (2006) Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol 7: 885-96.
34. Rosen ED, Walkey CJ, Puigserver P, Spiegelman BM (2000) Transcriptional regulation of adipogenesis. Genes Dev 14: 1293-307.
35. Sakamaki J, Daitoku H, Yoshimochi K, Miwa M, Fukamizu A (2009) Regulation of FOXO1-mediated transcription and cell proliferation by PARP-1. Biochem Biophys Res Commun 382: 497-502.
36. Sekine K, Chen YR, Kojima N, Ogata K, Fukamizu A, Miyajima A (2007) Foxo1 links insulin signaling to C/EBPalpha and regulates gluconeogenesis during liver development. EMBO J 26: 3607-15.
37. Tang QQ (2003) CCAAT/enhancer-binding protein beta is required for mitotic clonal expansion during adipogenesis. Proc Natl Acad Sci 100: 850-5.
38. Tang QQ, Lane MD (2000) Role of C/EBP homologous protein (CHOP-10) in the programmed activation of CCAAT/enhanc-er-binding protein-beta during adipogenesis. Proc Natl Acad Sci 97: 12446-50.
39. Unger H Clark GO, Scherer PE, Orci L (2010) Lipid homeostasis,lipotoxicity and the metabolic syndrome. Biochim Biophys 1801: 209-14.
40. van der Vos KE, Coffer PJ (2011) The extending network of FOXO transcriptional target genes. Antioxid Redox Signal 14: 579-92.
41. Yeh WC, Cao Z, Classon M, McKnight SL (1995) Cascaderegulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins. Genes Dev 9: 168-81.
42. Yu ZK, Hausman GJ (1998) Expression of CCAAT/enhancer binding proteins during porcine preadipocyte differentiation.Exp Cell Res 245: 343-9.
43. Yuan Y, Shi XE, Liu YG, Yang GS (2011) FoxO1 regulates muscle fiber-type specification and inhibits calcineurin signaling during C2C12 myoblast differentiation. Mol Cell Biochem 348: 77-87.