Expression of C/EBPα, β and δ in fetal and postnatal subcutaneous adipose tissue

Molecular and Cellular Biochemistry

Volumn 178, Issue 1-2, 1998, Pages 269-274

  Lee, Kichoon ^a   Hausman, Gary J ^b   Dean, Roger G ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b RUSSELL RESEARCH CENTER   (United States)

Author keywords

Adipose development; C EBP ; C EBP ; C EBP

Indexed keywords

TRANSCRIPTION FACTOR;

ADIPOSE TISSUE; ANIMAL TISSUE; ARTICLE; FETUS; FETUS LIVER; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; NONHUMAN; POSTNATAL DEVELOPMENT; SUBCUTANEOUS FAT; SWINE;

ADIPOSE TISSUE; ANIMALS; CCAAT-ENHANCER-BINDING PROTEINS; DNA-BINDING PROTEINS; FEMALE; GESTATIONAL AGE; LIVER; NUCLEAR PROTEINS; PREGNANCY; SWINE; TRANSCRIPTION FACTORS;

EID: 0031936338     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006846910046     Document Type: Article

References (30)

1. Birkenmeier EH, Gwynn B, Howard S, Jerry J, Gordon JL, Landschulz WH, McKnight SL: Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein. Genes Dev 3: 1146-1156, 1989
2. Christy RJ, Yang VW, Ntambi JM, Geiman DE, Landschulz WH, Friedman AD, Nakabeppu Y, Kelly TJ, Lane MD: Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte specific genes. Genes Dev 3: 1323-1335, 1989
3. Christy RJ, Yang VW, Ntambi JM, Geiman DE, Landschulz WH, Lane MD: CCAAT/enhancer binding protein gene promoter: Binding of nuclear factors during differentiation of 3T3-L1 adipocytes. Proc Natl Acad Sci 88: 2593-2597, 1991
4. Yeh W-C, Cao Z, Classon M, McKnight SL: Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins. Genes Dev 9: 168-181, 1995
5. Hwang C-S, Mandrup S, MacDougald OA, Geiman DE, Lane MD: Transcriptional activation of the mouse obese (ob) gene by CCAAT/enhancer binding protein α. Proc Natl Acad Sci 93: 873-877, 1996
6. Wu Z, Xie Y, Bucher N, Farmer SR: Conditional ectopic expression of C/EBPγ in NIH-3T3 cells induces PPARy and stimulates adipogenesis. Genes Dev 9: 2350-2363, 1995
7. Kaestner KH, Christy RJ, Lane MD: Mouse insulin-responsive glucose transporter gene: Characterization of the gene and trans-activation by the CCAAT/enhancer binding protein. Proc Natl Acad Sci 87: 251-255, 1990
8. McKeon C, Pham T: Transactivation of the insulin receptor gene by the CAAT/enhancer binding protein. Biochem Biophy Res Comm 174: 721-728, 1991
9. Park EA, Roesler WJ, Liu J, Klemm DJ, Gurney AL, Thatcher JD, Shuman J, Friedman A, Hanson RW: The role of the CCAAT/enhancer-binding protein in the transcriptional regulation of the gene for phosphoenolpyruvate carboxykinase (GTP). Mol Cell Biol 10: 6264-6272, 1990
10. Lin F-T, Lane MD: CCAAT/enhancer binding protein a is sufficient to initiate the 3T3-L1 adipocyte differentiation program. Proc Natl Acad Sci 91: 8757-8761, 1994
11. Freytag SO, Paielli DL, Gilbert JD: Ectopic expression of the CCAAT/enhancer-binding protein a promotes the adipogenic program in a variety of mouse fibroblastic cells. Genes Dev 8: 1654-1663, 1994
12. Lin F-T, Lane MD: Antisense CCAAT/enhancer binding protein RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 adipocytes. Genes Dev 6: 533-544, 1992
13. Samuelsson L, Stromberg K, Vikman K, Bjursell G, Enerback S: The CCAAT/ enhancer binding protein and its role in adipocyte differentiation: Evidence for direct involvement in terminal adipocyte development. EMBO J 10: 3787-3793, 1991
14. Wang N-d, Finegold MJ, Bradley A, Ou CN, Abdelsayed SV, Wilde MD, Taylor LR, Wilson DR, Darlington GJ: Impaired energy homeostasis in C/EBPα knockout mice. Science 269: 1108-1112, 1995
15. Umek RM, Friedman AD, McKnight SL: CCAAT-Enhancer binding protein: A component of a differentiation switch. Science 251: 288-251, 1991
16. Timchenko NA, Wilde M, Nakanishi M, Smith JR, Darlington GJ: CCAAT/enhancer-binding protein α (C/EBPα) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein. Genes Dev 10: 804-815, 1990
17. Cao Z, Umek RM, McKnight SL: Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev 5: 1538-1552, 1991
18. Wu Z, Bucher N, Farmer SR: Induction of peroxisome proliferator-activated receptor during the conversion of 3T3 fibroblasts into adipocytes is mediated by C/EBPp, 14 C/EBPβ and glucocorticoids. Mol Cell Biol 8: 4128-4136, 1996
19. Hausman GJ, Novakofski JE, Martin RJ, Thomas GB: The development of adipocytes in primary stromal-vascular culture of fetal adipose tissue. Cell Tissue Res 236: 459-464, 1984
20. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970
21. Yu ZK, Hausman GJ: Expression of CCAAT/enhancer binding proteins during porcine preadipocyte differentiation. Exp Cell Res (in press)
22. Hausman GJ, Thomas GB: The development of the inner layer of backfat in fetal end young pigs. J Anim Sci 58: 1550-1560, 1983
23. Hausman GJ, Wright JT, Jewell DE, Ramsay TG: Fetal adipose tissue development. Internatl J Obesity 14: 177-185, 1990
24. Lin F-T, MacDougald OA, Diehl AM, Lane MD: A 30 kDa alternative translation product of the CCAAT/enhancer binding protein a message: Transcriptional activator lacking antimitotic activity. Proc Natl Acad Sci 90: 9606-9610, 1993
25. Descombes P, Chojkier M, Lichtsteiner S, Falvey E, Schibler: U. LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein. Genes Dev 4: 1541-1551, 1990
26. Clarkson RWE, Chen CM, Harrison S, Wells C, Muscat GEO, Waters MJ: Early response of trans-activating factors to growth hormone in preadipocytes: Differential regulation of CCAAT enhancer-binding protein-β (C/EBPβ) and C/EBPδ. Mol Endocrinol 9: 108-120, 1995
27. 3) and insulin-like growth factor- 1 (IGF-1) on the differentiation of preadipocytes in serum-free cultures of pig stromal-vascular cells. J Anim Sci 67: 3136-3143, 1989
28. An MR, Hsieh CC, Reisner PD, Rabek JP, Scoot SG, Kuninger DT, Papaconstantinou J: Evidence for postranscriptional regulation of C/EBPα and C/EBPβ isoform expression during the lipopolysaccharidemediated acute-phase response. Mol Cell Biol 16: 2295-2306, 1996
29. Herbein JH, Martin RJ, Griel LC, Kavanaugh JF: Serum hormones in the perinatal pig and the effect of exogenous insulin on blood sugars. Growth 41: 277-283, 1977
30. MacDougald OA, Cornelius P, Liu R, Lane MD: Insulin regulates transcription of the CCAAT/enhancer binding protein (C/EBP) α, β, and δ genes in fully-differentiated 3T3-L1 adipocytes. J Biol Chem 270: 647-654, 1995