The promise of sulfated synthetic small molecules as modulators of glycosaminoglycan function

Future Medicinal Chemistry

Volumn 5, Issue 12, 2013, Pages 1363-1366

  Desai, Umesh R ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Drug design; Enzyme inhibitors; Glycosaminoglycans; Mimetics; Proteoglycans; Small molecules; Structure function relationship; Sulfation; Synthesis

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBIN; BIOPOLYMER; BLOOD CLOTTING FACTOR 11A; ENZYME INHIBITOR; GAG PROTEIN; GLYCOSAMINOGLYCAN; GLYCOSAMINOGLYCAN POLYSULFATE; HEPARIN; PROTEOGLYCAN; QUINAZOLINONE DERIVATIVE; SYNTHETIC PEPTIDE;

AMINO ACID SEQUENCE; BIOLOGICAL ACTIVITY; DRUG DESIGN; DRUG PURIFICATION; DRUG SYNTHESIS; EMBRYONIC STEM CELL; ENDOCYTOSIS; HYDROGEN BOND; PATENT; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; STRUCTURE ACTIVITY RELATION; SULFATION;

EID: 84881538094     PISSN: 17568919     EISSN: 17568927     Source Type: Journal    
DOI: 10.4155/fmc.13.117     Document Type: Review

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