Proteomic analysis reveals that pardaxin triggers apoptotic signaling pathways in human cervical carcinoma HeLa cells: Cross talk among the UPR, c-Jun and ROS

Carcinogenesis

Volumn 34, Issue 8, 2013, Pages 1833-1842

  Huang, Tsui Chin ^a,b   Chen, Jyh Yih ^a  

^a INSTITUTE OF CELLULAR AND ORGANISMIC BIOLOGY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

PARDAXIN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR AP 1;

APOPTOSIS; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSKELETON; CYTOTOXICITY; HELA CELL; HUMAN; HUMAN CELL; ONCOGENE C JUN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PHOSPHORYLATION; PROTEOMICS; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

EID: 84881533679     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgt130     Document Type: Article

References (46)

1. Zasloff, M. (2002) Antimicrobial peptides of multicellular organisms. Nature, 415, 389-395.
2. Jenssen, H. et al. (2006) Peptide antimicrobial agents. Clin. Microbiol. Rev., 19, 491-511.
3. Yount, N.Y. et al. (2006) Advances in antimicrobial peptide immunobiology. Biopolymers, 84, 435-458.
4. Splith, K. et al. (2011) Antimicrobial peptides with cell-penetrating peptide properties and vice versa. Eur. Biophys. J., 40, 387-397.
5. Nguyen, L.T. et al. (2011) The expanding scope of antimicrobial peptide structures and their modes of action. Trends Biotechnol., 29, 464-472.
6. Primor, N. et al. (1980) Conformation of pardaxin, the toxin of the flatfish Pardachirus marmoratus. Biochim. Biophys. Acta, 626, 299-306.
7. Pal, R. et al. (1981) Transcription of vesicular stomatitis virus activated by pardaxin, a fish toxin that permeabilizes the virion membrane. J. Virol., 39, 641-645.
8. Primor, N. et al. (1981) Pardachirus marmoratus (Red Sea flatfish) secretion and its isolated toxic fraction pardaxin: the relationship between hemolysis and ATPase inhibition. Toxicon, 19, 573-578.
9. Hsu, J.C. et al. (2011) Pardaxin-induced apoptosis enhances antitumor activity in HeLa cells. Peptides, 32, 1110-1116.
10. Huang, T.C. et al. (2011) Pardaxin, an antimicrobial peptide, triggers caspase-dependent and ROS-mediated apoptosis in HT-1080 cells. Mar. Drugs, 9, 1995-2009.
11. Taylor, R.C. et al. (2008) Apoptosis: controlled demolition at the cellular level. Nat. Rev. Mol. Cell Biol., 9, 231-241.
12. Pradelli, L.A. et al. (2010) Mitochondrial control of caspase-dependent and -independent cell death. Cell. Mol. Life Sci., 67, 1589-1597.
13. Moore, K. et al. (2012) The unfolded protein response in secretory cell function. Annu. Rev. Genet., 46, 165-183.
14. Benhar, M. et al. (2002) ROS, stress-activated kinases and stress signaling in cancer. EMBO Rep., 3, 420-425.
15. Jeong, S.W. et al. (2010) Gentamicin-induced spiral ganglion cell death: apoptosis mediated by ROS and the JNK signaling pathway. Acta Otolaryngol., 130, 670-678.
16. Malich, G. et al. (1997) The sensitivity and specificity of the MTS tetrazolium assay for detecting the in vitro cytotoxicity of 20 chemicals using human cell lines. Toxicology, 124, 179-192.
17. Huang, T.C. et al. (2008) Targeting therapy for breast carcinoma by ATP synthase inhibitor aurovertin B. J. Proteome Res., 7, 1433-1444.
18. Tait, S.W. et al. (2010) Mitochondria and cell death: outer membrane permeabilization and beyond. Nat. Rev. Mol. Cell Biol., 11, 621-632.
19. Candé,C. et al. (2004) Apoptosis-inducing factor (AIF): caspase-independent after all. Cell Death Differ., 11, 591-595.
20. Ryter, S.W. et al. (2007) Mechanisms of cell death in oxidative stress. Antioxid. Redox Signal., 9, 49-89.
21. Whelan, R.S. et al. (2010) Cell death in the pathogenesis of heart disease: mechanisms and significance. Annu. Rev. Physiol., 72, 19-44.
22. Ndozangue-Touriguine, O. et al. (2008) Cytoskeleton and apoptosis. Biochem. Pharmacol., 76, 11-18.
23. Wu, W.S. (2006) The signaling mechanism of ROS in tumor progression. Cancer Metastasis Rev., 25, 695-705.
24. Doherty, T. et al. (2006) Peptide-lipid interactions of the beta-hairpin antimicrobial peptide tachyplesin and its linear derivatives from solid-state NMR. Biochim. Biophys. Acta, 1758, 1285-1291.
25. Gifford, J.L. et al. (2005) Lactoferricin: a lactoferrin-derived peptide with antimicrobial, antiviral, antitumor and immunological properties. Cell. Mol. Life Sci., 62, 2588-2598.
26. van Meer, G. et al. (2008) Membrane lipids: where they are and how they behave. Nat. Rev. Mol. Cell Biol., 9, 112-124.
27. Bretscher, M.S. (1972) Asymmetrical lipid bilayer structure for biological membranes. Nature, 236, 11-12.
28. Epand, R.F. et al. (2007) Bacterial lipid composition and the antimicrobial efficacy of cationic steroid compounds (Ceragenins). Biochim. Biophys. Acta, 1768, 2500-2509.
29. Dobrzynska, I. et al. (2005) Changes in electric charge and phospholipids composition in human colorectal cancer cells. Mol. Cell. Biochem., 276, 113-119.
30. Lunt, S.Y. et al. (2011) Aerobic glycolysis: meeting the metabolic requirements of cell proliferation. Annu. Rev. Cell Dev. Biol., 27, 441-464.
31. Hoskin, D.W. et al. (2008) Studies on anticancer activities of antimicrobial peptides. Biochim. Biophys. Acta, 1778, 357-375.
32. Berridge, M.V. et al. (2009) Targeting mitochondrial permeability in cancer drug development. Mol. Nutr. Food Res., 53, 76-86.
33. Yang, J. et al. (1997) Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science, 275, 1129-1132.
34. Zhang, B. et al. (2005) Rho GDP dissociation inhibitor protects cancer cells against drug-induced apoptosis. Cancer Res., 65, 6054-6062.
35. Ellgaard, L. et al. (2001) ER quality control: towards an understanding at the molecular level. Curr. Opin. Cell Biol., 13, 431-437.
36. Li, J. et al. (2008) The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells. Cell Death Differ., 15, 1460-1471.
37. Vedrenne, C. et al. (2006) Morphogenesis of the endoplasmic reticulum: beyond active membrane expansion. Traffic, 7, 639-646.
38. Rutkowski, D.T. et al. (2004) A trip to the ER: coping with stress. Trends Cell Biol., 14, 20-28.
39. Malhotra, J.D. et al. (2007) Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword? Antioxid. Redox Signal., 9, 2277-2293.
40. Verkhratsky, A. (2007) Calcium and cell death. Subcell. Biochem., 45, 465-480.
41. Breckenridge, D.G. et al. (2003) Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol. J. Cell Biol., 160, 1115-1127.
42. Brookes, P.S. et al. (2004) Calcium, ATP, and ROS: a mitochondrial lovehate triangle. Am. J. Physiol. Cell Physiol., 287, C817-C833.
43. Shen, H.M. et al. (2006) JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species. Free Radic. Biol. Med., 40, 928-939.
44. Holtz, W.A. et al. (2006) Oxidative stress-triggered unfolded protein response is upstream of intrinsic cell death evoked by Parkinsonian mimetics. J. Neurochem., 99, 54-69.
45. Zhang, K. et al. (2008) From endoplasmic-reticulum stress to the inflammatory response. Nature, 454, 455-462.
46. Park, Y.J. et al. (2009) The RhoGDI-alpha/JNK signaling pathway plays a significant role in mycophenolic acid-induced apoptosis in an insulinsecreting cell line. Cell. Signal., 21, 356-364.