Gentamicin-induced spiral ganglion cell death: Apoptosis mediated by ROS and the JNK signaling pathway

Acta Oto-Laryngologica

Volumn 130, Issue 6, 2010, Pages 670-678

  Jeong, Sung Wook ^a   Kim, Lee Suk ^a   Hur, Daeyoung ^b   Bae, Woo Yong ^a   Kim, Jae Ryong ^c   Lee, Jae Hoon ^a  

^a Dong A University   (South Korea)

^b Department of Anatomy and Tumor Immunology ^*  (South Korea)

^c Inje University   (South Korea)

Author keywords

Apoptosis; C Jun; Gentamicin; JNK; Reactive oxygen species; Spiral ganglion cell

Indexed keywords

FAS LIGAND; GENTAMICIN; HYDROETHIDINE; PROTEIN C JUN; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL LOSS; CELL POPULATION; CELL STRUCTURE; COCHLEA; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FLUORESCENCE ANALYSIS; GUINEA PIG; HAIR CELL; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPIRAL GANGLION; STRUCTURE ANALYSIS; WESTERN BLOTTING;

ANIMALS; ANTI-BACTERIAL AGENTS; APOPTOSIS; FAS LIGAND PROTEIN; GENTAMICINS; GUINEA PIGS; HAIR CELLS, AUDITORY; IN SITU NICK-END LABELING; JNK MITOGEN-ACTIVATED PROTEIN KINASES; POLYMERASE CHAIN REACTION; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SPIRAL GANGLION;

EID: 77952283372     PISSN: 00016489     EISSN: 16512553     Source Type: Journal    
DOI: 10.3109/00016480903428200     Document Type: Article

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