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Volumn 24, Issue 2, 2013, Pages 151-166

Chromatin-bound IκBα regulates a subset of polycomb target genes in differentiation and cancer

(27)  Mulero, MaríaCarmen a   Ferres Marco, Dolors b   Islam, Abul c,d   Margalef, Pol a   Pecoraro, Matteo e   Toll, Agustí a   Drechsel, Nils a   Charneco, Cristina a   Davis, Shelly f   Bellora, Nicolás c   Gallardo, Fernando a   López Arribillaga, Erika a   Asensio Juan, Elena a   Rodilla, Verónica a   González, Jessica a   Iglesias, Mar a   Shih, Vincent g   MarAlba M c,h   DiCroce, Luciano e,h   Hoffmann, Alexander g   more..


Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B ALPHA;

EID: 84881519604     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccr.2013.06.003     Document Type: Article
Times cited : (44)

References (52)
  • 1
    • 9344233282 scopus 로고    scopus 로고
    • Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression
    • Aguilera C., Hoya-Arias R., Haegeman G., Espinosa L., Bigas A. Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression. Proc. Natl. Acad. Sci. USA 2004, 101:16537-16542.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 16537-16542
    • Aguilera, C.1    Hoya-Arias, R.2    Haegeman, G.3    Espinosa, L.4    Bigas, A.5
  • 3
    • 0023724778 scopus 로고
    • I kappa B: a specific inhibitor of the NF-kappa B transcription factor
    • Baeuerle P.A., Baltimore D. I kappa B: a specific inhibitor of the NF-kappa B transcription factor. Science 1988, 242:540-546.
    • (1988) Science , vol.242 , pp. 540-546
    • Baeuerle, P.A.1    Baltimore, D.2
  • 4
    • 0028971291 scopus 로고
    • Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in Ikappa B alpha-deficient mice
    • Beg A.A., Sha W.C., Bronson R.T., Baltimore D. Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in Ikappa B alpha-deficient mice. Genes Dev. 1995, 9:2736-2746.
    • (1995) Genes Dev. , vol.9 , pp. 2736-2746
    • Beg, A.A.1    Sha, W.C.2    Bronson, R.T.3    Baltimore, D.4
  • 5
    • 34250305146 scopus 로고    scopus 로고
    • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
    • ENCODE Project Consortium, NISC Comparative Sequencing ProgramNISC Comparative Sequencing Program, Baylor College of Medicine Human Genome Sequencing CenterBaylor College of Medicine Human Genome Sequencing Center, Washington University Genome Sequencing CenterWashington University Genome Sequencing Center, Broad InstituteBroad Institute, Children's Hospital Oakland Research InstituteChildren's Hospital Oakland Research Institute
    • Birney E., Stamatoyannopoulos J.A., Dutta A., Guigó R., Gingeras T.R., Margulies E.H., Weng Z., Snyder M., Dermitzakis E.T., Thurman R.E., et al. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007, 447:799-816. ENCODE Project Consortium, NISC Comparative Sequencing ProgramNISC Comparative Sequencing Program, Baylor College of Medicine Human Genome Sequencing CenterBaylor College of Medicine Human Genome Sequencing Center, Washington University Genome Sequencing CenterWashington University Genome Sequencing Center, Broad InstituteBroad Institute, Children's Hospital Oakland Research InstituteChildren's Hospital Oakland Research Institute.
    • (2007) Nature , vol.447 , pp. 799-816
    • Birney, E.1    Stamatoyannopoulos, J.A.2    Dutta, A.3    Guigó, R.4    Gingeras, T.R.5    Margulies, E.H.6    Weng, Z.7    Snyder, M.8    Dermitzakis, E.T.9    Thurman, R.E.10
  • 8
    • 0032555927 scopus 로고    scopus 로고
    • Functional redundancy of the nuclear factor kappa B inhibitors I kappa B alpha and I kappa B beta
    • Cheng J.D., Ryseck R.P., Attar R.M., Dambach D., Bravo R. Functional redundancy of the nuclear factor kappa B inhibitors I kappa B alpha and I kappa B beta. J.Exp. Med. 1998, 188:1055-1062.
    • (1998) J.Exp. Med. , vol.188 , pp. 1055-1062
    • Cheng, J.D.1    Ryseck, R.P.2    Attar, R.M.3    Dambach, D.4    Bravo, R.5
  • 10
    • 34548644772 scopus 로고    scopus 로고
    • The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
    • De Santa F., Totaro M.G., Prosperini E., Notarbartolo S., Testa G., Natoli G. The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. Cell 2007, 130:1083-1094.
    • (2007) Cell , vol.130 , pp. 1083-1094
    • De Santa, F.1    Totaro, M.G.2    Prosperini, E.3    Notarbartolo, S.4    Testa, G.5    Natoli, G.6
  • 12
    • 24344474463 scopus 로고    scopus 로고
    • Crystallographic refinement by knowledge-based exploration of complex energy landscapes
    • Depristo M.A., de Bakker P.I., Johnson R.J., Blundell T.L. Crystallographic refinement by knowledge-based exploration of complex energy landscapes. Structure 2005, 13:1311-1319.
    • (2005) Structure , vol.13 , pp. 1311-1319
    • Depristo, M.A.1    de Bakker, P.I.2    Johnson, R.J.3    Blundell, T.L.4
  • 13
    • 0032135131 scopus 로고    scopus 로고
    • SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation
    • Desterro J.M., Rodriguez M.S., Hay R.T. SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation. Mol. Cell 1998, 2:233-239.
    • (1998) Mol. Cell , vol.2 , pp. 233-239
    • Desterro, J.M.1    Rodriguez, M.S.2    Hay, R.T.3
  • 14
    • 43249114058 scopus 로고    scopus 로고
    • Repression of gene expression by unphosphorylated NF-kappaB p65 through epigenetic mechanisms
    • Dong J., Jimi E., Zhong H., Hayden M.S., Ghosh S. Repression of gene expression by unphosphorylated NF-kappaB p65 through epigenetic mechanisms. Genes Dev. 2008, 22:1159-1173.
    • (2008) Genes Dev. , vol.22 , pp. 1159-1173
    • Dong, J.1    Jimi, E.2    Zhong, H.3    Hayden, M.S.4    Ghosh, S.5
  • 15
    • 0037326023 scopus 로고    scopus 로고
    • IkappaBalpha and p65 regulate the cytoplasmic shuttling of nuclear corepressors: cross-talk between Notch and NFkappaB pathways
    • Espinosa L., Inglés-Esteve J., Robert-Moreno A., Bigas A. IkappaBalpha and p65 regulate the cytoplasmic shuttling of nuclear corepressors: cross-talk between Notch and NFkappaB pathways. Mol. Biol. Cell 2003, 14:491-502.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 491-502
    • Espinosa, L.1    Inglés-Esteve, J.2    Robert-Moreno, A.3    Bigas, A.4
  • 16
    • 84864435391 scopus 로고    scopus 로고
    • Alternative nuclear functions for NF-κB family members
    • Espinosa L., Bigas A., Mulero M.C. Alternative nuclear functions for NF-κB family members. Am. J. Cancer Res. 2011, 1:446-459.
    • (2011) Am. J. Cancer Res. , vol.1 , pp. 446-459
    • Espinosa, L.1    Bigas, A.2    Mulero, M.C.3
  • 17
    • 62149122634 scopus 로고    scopus 로고
    • Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells
    • Ezhkova E., Pasolli H.A., Parker J.S., Stokes N., Su I.H., Hannon G., Tarakhovsky A., Fuchs E. Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells. Cell 2009, 136:1122-1135.
    • (2009) Cell , vol.136 , pp. 1122-1135
    • Ezhkova, E.1    Pasolli, H.A.2    Parker, J.S.3    Stokes, N.4    Su, I.H.5    Hannon, G.6    Tarakhovsky, A.7    Fuchs, E.8
  • 18
    • 79952220410 scopus 로고    scopus 로고
    • EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair
    • Ezhkova E., Lien W.H., Stokes N., Pasolli H.A., Silva J.M., Fuchs E. EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair. Genes Dev. 2011, 25:485-498.
    • (2011) Genes Dev. , vol.25 , pp. 485-498
    • Ezhkova, E.1    Lien, W.H.2    Stokes, N.3    Pasolli, H.A.4    Silva, J.M.5    Fuchs, E.6
  • 19
    • 34848864644 scopus 로고    scopus 로고
    • Epidermal stem cells are defined by global histone modifications that are altered by Myc-induced differentiation
    • Frye M., Fisher A.G., Watt F.M. Epidermal stem cells are defined by global histone modifications that are altered by Myc-induced differentiation. PLoS ONE 2007, 2:e763.
    • (2007) PLoS ONE , vol.2
    • Frye, M.1    Fisher, A.G.2    Watt, F.M.3
  • 20
    • 0026486817 scopus 로고
    • Cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the I kappa B gene family of vertebrates
    • Geisler R., Bergmann A., Hiromi Y., Nüsslein-Volhard C. cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the I kappa B gene family of vertebrates. Cell 1992, 71:613-621.
    • (1992) Cell , vol.71 , pp. 613-621
    • Geisler, R.1    Bergmann, A.2    Hiromi, Y.3    Nüsslein-Volhard, C.4
  • 22
    • 0018865014 scopus 로고
    • Calcium regulation of growth and differentiation of mouse epidermal cells in culture
    • Hennings H., Michael D., Cheng C., Steinert P., Holbrook K., Yuspa S.H. Calcium regulation of growth and differentiation of mouse epidermal cells in culture. Cell 1980, 19:245-254.
    • (1980) Cell , vol.19 , pp. 245-254
    • Hennings, H.1    Michael, D.2    Cheng, C.3    Steinert, P.4    Holbrook, K.5    Yuspa, S.H.6
  • 23
    • 0034960907 scopus 로고    scopus 로고
    • Postrepression activation of NF-kappaB requires the amino-terminal nuclear export signal specific to IkappaBalpha
    • Huang T.T., Miyamoto S. Postrepression activation of NF-kappaB requires the amino-terminal nuclear export signal specific to IkappaBalpha. Mol. Cell. Biol. 2001, 21:4737-4747.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 4737-4747
    • Huang, T.T.1    Miyamoto, S.2
  • 24
    • 0033953587 scopus 로고    scopus 로고
    • A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes
    • Huang T.T., Kudo N., Yoshida M., Miyamoto S. A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes. Proc. Natl. Acad. Sci. USA 2000, 97:1014-1019.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 1014-1019
    • Huang, T.T.1    Kudo, N.2    Yoshida, M.3    Miyamoto, S.4
  • 26
    • 0036843170 scopus 로고    scopus 로고
    • Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencing
    • Kimura A., Umehara T., Horikoshi M. Chromosomal gradient of histone acetylation established by Sas2p and Sir2p functions as a shield against gene silencing. Nat. Genet. 2002, 32:370-377.
    • (2002) Nat. Genet. , vol.32 , pp. 370-377
    • Kimura, A.1    Umehara, T.2    Horikoshi, M.3
  • 29
    • 0029120078 scopus 로고
    • The dorsal protein enhances the biosynthesis and stability of the Drosophila I kappa B homologue cactus
    • Kubota K., Gay N.J. The dorsal protein enhances the biosynthesis and stability of the Drosophila I kappa B homologue cactus. Nucleic Acids Res. 1995, 23:3111-3118.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 3111-3118
    • Kubota, K.1    Gay, N.J.2
  • 30
    • 0028877993 scopus 로고
    • Functional analysis and regulation of nuclear importof dorsal during the immune response in Drosophila
    • Lemaitre B., Meister M., Govind S., Georgel P., Steward R., Reichhart J.M., Hoffmann J.A. Functional analysis and regulation of nuclear importof dorsal during the immune response in Drosophila. EMBO J. 1995, 14:536-545.
    • (1995) EMBO J. , vol.14 , pp. 536-545
    • Lemaitre, B.1    Meister, M.2    Govind, S.3    Georgel, P.4    Steward, R.5    Reichhart, J.M.6    Hoffmann, J.A.7
  • 32
    • 0041624288 scopus 로고    scopus 로고
    • Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27
    • Min J., Zhang Y., Xu R.M. Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27. Genes Dev. 2003, 17:1823-1828.
    • (2003) Genes Dev. , vol.17 , pp. 1823-1828
    • Min, J.1    Zhang, Y.2    Xu, R.M.3
  • 33
    • 43749098070 scopus 로고    scopus 로고
    • NF-kappaB and cancer-identifying targets and mechanisms
    • Naugler W.E., Karin M. NF-kappaB and cancer-identifying targets and mechanisms. Curr. Opin. Genet. Dev. 2008, 18:19-26.
    • (2008) Curr. Opin. Genet. Dev. , vol.18 , pp. 19-26
    • Naugler, W.E.1    Karin, M.2
  • 37
    • 66449099403 scopus 로고    scopus 로고
    • The Nfkb1 and Nfkb2 proteins p105 and p100 function as the core of high-molecular-weight heterogeneous complexes
    • Savinova O.V., Hoffmann A., Ghosh G. The Nfkb1 and Nfkb2 proteins p105 and p100 function as the core of high-molecular-weight heterogeneous complexes. Mol. Cell 2009, 34:591-602.
    • (2009) Mol. Cell , vol.34 , pp. 591-602
    • Savinova, O.V.1    Hoffmann, A.2    Ghosh, G.3
  • 38
    • 66449092314 scopus 로고    scopus 로고
    • Kinetic control of negative feedback regulators of NF-kappaB/RelA determines their pathogen- and cytokine-receptor signaling specificity
    • Shih V.F., Kearns J.D., Basak S., Savinova O.V., Ghosh G., Hoffmann A. Kinetic control of negative feedback regulators of NF-kappaB/RelA determines their pathogen- and cytokine-receptor signaling specificity. Proc. Natl. Acad. Sci. USA 2009, 106:9619-9624.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 9619-9624
    • Shih, V.F.1    Kearns, J.D.2    Basak, S.3    Savinova, O.V.4    Ghosh, G.5    Hoffmann, A.6
  • 39
    • 32444434989 scopus 로고    scopus 로고
    • Histone H4-K16 acetylation controls chromatin structure and protein interactions
    • Shogren-Knaak M., Ishii H., Sun J.M., Pazin M.J., Davie J.R., Peterson C.L. Histone H4-K16 acetylation controls chromatin structure and protein interactions. Science 2006, 311:844-847.
    • (2006) Science , vol.311 , pp. 844-847
    • Shogren-Knaak, M.1    Ishii, H.2    Sun, J.M.3    Pazin, M.J.4    Davie, J.R.5    Peterson, C.L.6
  • 40
    • 0027264608 scopus 로고
    • Elements of the Drosophila bithorax complex that mediate repression by Polycomb group products
    • Simon J., Chiang A., Bender W., Shimell M.J., O'Connor M. Elements of the Drosophila bithorax complex that mediate repression by Polycomb group products. Dev. Biol. 1993, 158:131-144.
    • (1993) Dev. Biol. , vol.158 , pp. 131-144
    • Simon, J.1    Chiang, A.2    Bender, W.3    Shimell, M.J.4    O'Connor, M.5
  • 41
    • 0036842129 scopus 로고    scopus 로고
    • Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin
    • Suka N., Luo K., Grunstein M. Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin. Nat. Genet. 2002, 32:378-383.
    • (2002) Nat. Genet. , vol.32 , pp. 378-383
    • Suka, N.1    Luo, K.2    Grunstein, M.3
  • 42
    • 76149120388 scopus 로고    scopus 로고
    • AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
    • Trott O., Olson A.J. AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J.Comput. Chem. 2010, 31:455-461.
    • (2010) J.Comput. Chem. , vol.31 , pp. 455-461
    • Trott, O.1    Olson, A.J.2
  • 43
    • 67650724069 scopus 로고    scopus 로고
    • Regulation and function of NF-kappaB transcription factors in the immune system
    • Vallabhapurapu S., Karin M. Regulation and function of NF-kappaB transcription factors in the immune system. Annu. Rev. Immunol. 2009, 27:693-733.
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 693-733
    • Vallabhapurapu, S.1    Karin, M.2
  • 44
    • 0032751323 scopus 로고    scopus 로고
    • Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation
    • van der Vlag J., Otte A.P. Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation. Nat. Genet. 1999, 23:474-478.
    • (1999) Nat. Genet. , vol.23 , pp. 474-478
    • van der Vlag, J.1    Otte, A.P.2
  • 45
    • 0033565763 scopus 로고    scopus 로고
    • Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-kappaB signaling
    • van Hogerlinden M., Rozell B.L., Ahrlund-Richter L., Toftgård R. Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-kappaB signaling. Cancer Res. 1999, 59:3299-3303.
    • (1999) Cancer Res. , vol.59 , pp. 3299-3303
    • van Hogerlinden, M.1    Rozell, B.L.2    Ahrlund-Richter, L.3    Toftgård, R.4
  • 46
    • 3042646604 scopus 로고    scopus 로고
    • Characterization of the progressive skin disease and inflammatory cell infiltratein mice with inhibited NF-kappaB signaling
    • van Hogerlinden M., Rozell B.L., Toftgård R., Sundberg J.P. Characterization of the progressive skin disease and inflammatory cell infiltratein mice with inhibited NF-kappaB signaling. J.Invest. Dermatol. 2004, 123:101-108.
    • (2004) J.Invest. Dermatol. , vol.123 , pp. 101-108
    • van Hogerlinden, M.1    Rozell, B.L.2    Toftgård, R.3    Sundberg, J.P.4
  • 50
    • 0025304791 scopus 로고
    • Purified human I kappa B can rapidly dissociate the complex of the NF-kappa B transcription factor with its cognate DNA
    • Zabel U., Baeuerle P.A. Purified human I kappa B can rapidly dissociate the complex of the NF-kappa B transcription factor with its cognate DNA. Cell 1990, 61:255-265.
    • (1990) Cell , vol.61 , pp. 255-265
    • Zabel, U.1    Baeuerle, P.A.2
  • 51
    • 35948969388 scopus 로고    scopus 로고
    • Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion
    • Zhai Y., Kuick R., Nan B., Ota I., Weiss S.J., Trimble C.L., Fearon E.R., Cho K.R. Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion. Cancer Res. 2007, 67:10163-10172.
    • (2007) Cancer Res. , vol.67 , pp. 10163-10172
    • Zhai, Y.1    Kuick, R.2    Nan, B.3    Ota, I.4    Weiss, S.J.5    Trimble, C.L.6    Fearon, E.R.7    Cho, K.R.8
  • 52
    • 0035883954 scopus 로고    scopus 로고
    • Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails
    • Zhang Y., Reinberg D. Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails. Genes Dev. 2001, 15:2343-2360.
    • (2001) Genes Dev. , vol.15 , pp. 2343-2360
    • Zhang, Y.1    Reinberg, D.2


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