Reduced plasticity and mild cognitive impairment-like deficits after entorhinal lesions in hAPP/APOE4 mice

Neurobiology of Aging

Volumn 34, Issue 11, 2013, Pages 2683-2693

  Bott, Jean Bastien ^a   Cosquer, Brigitte ^a   Héraud, Céline ^a   Zerbinatti, Celina ^b   Kelche, Christian ^a   Cassel, Jean Christophe ^a   Mathis, Chantal ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Acetylcholine; Alzheimer disease (AD); Apolipoprotein E; Dentate gyrus; Entorhinal cortex; Mild cognitive impairment; Reactive synaptogenesis; Spatial navigation memory

Indexed keywords

ACETYLCHOLINESTERASE; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOE3 GENE; APOE4 GENE; APP GENE; ARTICLE; CHOLINERGIC SYSTEM; COGNITION; CONTROLLED STUDY; DENTATE GYRUS; ENTORHINAL CORTEX; ENZYME ACTIVITY; GENE; GENE ACTIVITY; GENE FUNCTION; GENOTYPE; MALE; MEMORY DISORDER; MILD COGNITIVE IMPAIRMENT; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; OLFACTORY NERVE INJURY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMELLING DISORDER; SPATIAL MEMORY;

ACETYLCHOLINE; ALZHEIMER DISEASE (AD); APOLIPOPROTEIN E; DENTATE GYRUS; ENTORHINAL CORTEX; MILD COGNITIVE IMPAIRMENT; REACTIVE SYNAPTOGENESIS; SPATIAL NAVIGATION MEMORY;

AGE FACTORS; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; APOLIPOPROTEIN E4; ATROPHY; BRAIN INJURIES; COGNITION DISORDERS; DARK ADAPTATION; ENTORHINAL CORTEX; EXCITATORY AMINO ACIDS; GENE EXPRESSION REGULATION; HUMANS; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; N-METHYLASPARTATE; RECOGNITION (PSYCHOLOGY); SYNAPSES;

EID: 84881512967     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2013.04.018     Document Type: Article

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