Evidence for recovery of spatial learning following entorhinal cortex lesions in mice

Brain Research

Volumn 758, Issue 1-2, 1997, Pages 187-200

  Hardman, R ^a,b   Evans, D J ^a   Fellows, L ^a   Hayes, B ^a   Rupniak, H T ^a   Barnes, J C ^a   Higgins, G A ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Entorhinal cortex lesion; GAP43; Morris water maze; Mouse; Plasticity; Spatial learning; Synaptophysin; Transgenic

Indexed keywords

NEUROMODULIN; SYNAPTOPHYSIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX LESION; COGNITION; CONTROLLED STUDY; DENERVATION; DENTATE GYRUS; ENTORHINAL CORTEX; HIPPOCAMPUS; IMMUNOREACTIVITY; LEARNING; MALE; MAZE TEST; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PERFORANT NERVE TRACT; PRIORITY JOURNAL; SPATIAL MEMORY; TASK PERFORMANCE;

ANIMALS; ENTORHINAL CORTEX; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; SPATIAL BEHAVIOR;

EID: 0030878112     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00223-0     Document Type: Article

References (53)

1. L.I. Benowitz, W.R. Rodriguez, R.L. Neve, The pattern of GAP-43 immunostaining changes in the rat hippocampal formation during reactive synaptogenesis, Mol. Brain Res. 8 (1990) 17-23.
2. L.I. Benowitz, A. Routtenberg, A membrane phosphoprotein associated with neural development, axonal regeneration, phospholipid metabolism, and synaptic plasticity, Trends Neurosci. 10 (1987) 527-532.
3. H. Braak, E. Braak, Neuropathological stageing of Alzheimer-related changes, Acta Neuropathol. 82 (1991) 239-259.
4. J. Bures, D. Buresova and J. Huston, Neurological tests in rats, in: Techniques and Basic Experiments for the Study of Brain and Behaviour, Elsevier, Amsterdam, The Netherlands, 1976.
5. H. Clusmann, R. Nitsch, U. Heineman, Long lasting functional alterations in the rat dentate gyrus: a current source density analysis, Neuroscience 61 (1994) 805-815.
6. T. Deller, R. Nitsch, M. Frotscher, Layer-specific sprouting of commisural fibres to the rat fascia dentata after unilateral entorhinal cortex lesion: a Phaseolus vulgaris leucoagglutinin tracing study, Neuroscience 71 (1996) 651-660.
7. S.L. Eastwood, P.W.J. Burnet, P.J. Harrison, Altered synaptophysin expression as a marker of synaptic pathology in schizophrenia, Neuroscience 66 (1995) 309-319.
8. M. Gauthier, B. Soumireu-Mourat, Behavioural effects of bilateral entorhinal cortex lesions in the Balb/c mouse, Behav. Neural Biol. 33 (1981) 419-436.
9. J.W. Geddes, D.T. Monaghan, C.W. Cotman, I.T. Lott, R.C. Kim, H.C. Chui, Plasticity of hippocampal circuitry in Alzheimer's disease, Science 230 (1985) 1179-1181.
10. S.G.N. Grant, A.J. Silva, Targeting learning, Trends Neurosci. 17 (1994) 71-75.
11. J.E. Hamos, L.J. DeGennaro, D.A. Drachman, Synaptic loss in Alzheimer's disease and other dementias, Neurology 39 (1989) 355-361.
12. O. Heinonen, H. Soininen, H. Sorvari, O. Kosunen, L. Paljarvi, E. Koivisto, P.J. Riekkinen, Loss of synaptophysin-like immunoreactivity in the hippocampal formation is an early phenomenon in Alzheimer's disease. Neuroscience 64 (1995) 375-384.
13. A. Hjorth-Simonsen, Projection of the lateral part of the entorhinal area to the hippocampus and fascia dentata, J. Comp. Neurol., 146 (1972) 219-232.
14. A. Hjorth-Simonsen, B. Jeune, Origin and termination of the hippocampal perforant path in the rat studied by silver impregnation, J. Comp. Neurol. 144 (1972) 215-232.
15. B.T. Hyman, G.W. VanHoesen, A.R. Damasio, Alzheimer's disease: glutamate depletion in the hippocampal perforant pathway zone, Ann. Neurol. 22 (1987) 37-40.
16. B.T. Hyman, G.W. VanHoesen, A.R. Damasio, C.L. Barnes, Alzheimer's disease: cell specific pathology isolates the hippocampal formation. Science 225 (1984) 1168-1170.
17. B.T. Hyman, G.W. VanHoesen, L.J. Kromer, A.R. Damasio, Perforant pathway changes and the memory impairment of Alzheimer's disease, Ann. Neurol. 20 (1986) 472-481.
18. R.S.G. Jones, Entorhinal-hippocampal connections: a speculative view of their function, Trends Neurosci. 16 (1993) 58-64.
19. J.P. Kesslak, A. Korotzer, A. Song, K. Kamali, C.W. Cotman, Effects of tetrahydroaminoacridine (THA) on functional recovery after sequential lesion of the entorhinal cortex, Brain Res. 557 (1991) 57-63.
20. J. Loesche, O. Steward, Behavioral correlates of denervation and reinnervation of the hippocampal formation of the rat: recovery of alternation performance following unilateral entorhinal cortex lesions, Brain Res. Bull. 2 (1977) 31-39.
21. G. Lynch, C. Gall, G. Rose, C. Cotman, Changes in the distribution of the dentate gyrus associational system following unilateral or bilateral entorhinal lesions in the adult rat, Brain Res. 110 (1976) 57-71.
22. G. Lynch, D.A. Matthews, S. Mosko, T. Parks, C.W. Cotman, Induced acetylcholinesterase-rich layer in rat dentate gyrus following entorhinal lesions, Brain Res. 42 (1972) 311-318.
23. E. Masliah, M. Mallory, M. Alford, N. Ge and L. Mucke, Abnormal synaptic regeneration in hAPP695 transgenic and ApoE knockout mice, in: K. Iqbal et al. (Eds.), Research Advances in Alzheimer's Disease and Related Disorders, John Wiley and Sons, 1995, pp. 405-414.
24. E. Masliah, A.M. Fagan, R.D. Terry, R. DeTeresa, M. Mallory, F.H. Gage, Reactive synaptogenesis assessed by synaptophysin immunoreactivity is associated with GAP-43 in the dentate gyrus of the adult rat, Exp. Neurol. 113 (1991) 131-142.
25. E. Masliah, M. Mallory, L. Hansen, R. DeTeresa, M. Alford, R. Terry, Synaptic and neuritic alterations during the progression of Alzheimer's disease, Neurosci. Lett. 174 (1994) 67-72.
26. D.A. Matthews, C. Cotman, G. Lynch, An electron microscope study of lesion-induced synaptogenesis in the dentate gyrus of the adult rat. I. Magnitude and time course of degeneration, Brain Res. 115 (1976) 1-21.
27. D.A. Matthews, C. Cotman, G. Lynch, An electron microscope study of lesion-induced synaptogenesis in the dentate gyrus of the adult rat. II. Reappearance of morphologically normal synaptic contacts, Brain Res. 115 (1976) 23-41.
28. M. Mayford, T. Abel, E.R. Kandel, Transgenic approaches to cognition, Curr. Opin. Neurobiol. 5 (1995) 141-148.
29. R.G.M. Morris, Spatial localisation does not require the presence of local cues, Learning Motiv. 12 (1981) 239-249.
30. R.G.M. Morris, P. Garrud, J.N.P. Rawlins, J. O'Keefe, Place navigation impaired in rats with hippocampal lesions, Nature 297 (1982) 681-683.
31. T. Myhrer, Locomotor and avoidance behavior in rats with partial or total hippocampal perforant path sections, Physiol. Behav. 15 (1975) 217-224.
32. T. Myhrer, Maze performance in rats with hippocampal perforant path lesions: some aspects of functional recovery. Physiol. Behav. 15 (1975) 433-437.
33. T. Myhrer, Animal models of Alzheimer's disease: glutamatergic denervation as an alternative approach to cholinergic denervation, Neurosci. Biobehav. Rev. 17 (1993) 195-202.
34. J. Poirier, Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease, Trends Neurosci. 17 (1994) 525-530.
35. J.J. Ramirez, B. Fadd, S.E. Karpaik, O. Steward, Ganglioside treatments reduce locomotor hyperactivity after bilateral lesions of the entorhinal cortex, Neurosci. Lett. 75 (1987) 283-287.
36. J.J. Ramirez, R. Labbe, D.G. Stein, Recovery from perseverative behavior after entorhinal cortex lesions in rats, Brain Res. 459 (1988) 153-156.
37. T.M. Reeves, D.C. Smith, Reinnervation of the dentate gyrus and recovery of alternation behavior following entorhinal cortex lesions, Behav. Neurosci. 101 (1987) 179-186.
38. S.W. Scheff, J. Tewes, S.A. Baldwin, J.W. Geddes, Synaptophysin and electron microscopic assessment of reactive synaptogenesis, Soc. Neurosci. Abstr. 20 (1994) 510-511.
39. F. Schenk, R.G.M. Morris, Dissociation between components of spatial memory in rats after recovery from the effects of retrohippocampal lesions, Exp. Brain Res. 58 (1985) 11-28.
40. R.W. Skelton, R.K. McNamara, Bilateral knife cuts to the perforant path disrupt spatial learning in the Morris water maze, Hippocampus 2 (1992) 73-80.
41. L.R. Squire, S. Zola-Morgan, The medial temporal lobe memory system, Science 253 (1991) 1380-1386.
42. B.B. Stanfield, W.M. Cowan, The sprouting of septal afferents to the dentate gyrus after lesions of the entorhinal cortex in adult rats, Brain Res. 232 (1982) 162-170.
43. O. Steward, Trajectory of contralateral entorhinal axons which reinnervate the fascia dentata of the rat following ipsilateral entorhinal lesions. Brain Res. 183 (1980) 277-289.
44. O. Steward, C.W. Cotman, G.S. Lynch, Re-establishment of electrophysiologically functional entorhinal cortical input to the dentate gyrus deafferented by ipsilateral entorhinal lesions: innervation by the contralateral entorhinal cortex, Exp. Brain Res. 18 (1973) 396-414.
45. O. Steward, S.L. Vinsant, The process of reinnervation in the dentate gyrus of the adult rat: a quantitative electron microscopic analysis of terminal proliferation and reactive synaptogenesis, J. Comp. Neurol. 214 (1983) 370-386.
46. R.P. Stroemer, T.A. Kent, C.E. Hulsebosch, Neocortical neural sprouting, synaptogenesis, and behavioural recovery after neocortical infarction in rats, Stroke 26 (1995) 2135-2144.
47. R.J. Sutherland, B. Kolb, I.Q. Wishaw, Spatial mapping: definative disruption by hippocampal or medial frontal cortical damage in the rat, Neurosci. Lett. 31 (1982) 271-276.
48. N. Tamamaki, Y. Nojyo, Projection of the entorhinal layer II neurons in the rat as revealed by intracellular pressure-injection of neurobiotin. Hippocampus 3 (1993) 471-480.
49. R.D. Terry, E. Masliah, D.P. Salmon, N. Butters, R. DeTeresa, R. Hill, L.A. Hansen, R. Katzman, Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment, Ann. Neurol. 30 (1991) 572-580.
50. D.E. Tupper, R.B. Wallace, Utility of the neurological examination in rats, Acta Neurobiol. Exp. 40 (1980) 999-1003.
51. B. Wiedenmann, W.W. Franke, Identification and localisation of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles, Cell 41 (1985) 1017-1028.
52. R.C. Wilson, W.B. Levy, O. Steward, Functional effects of lesioninduced plasticity, long term potentiation in normal and lesion-induced temporodentate connections. Brain Res. 176 (1979) 65-78.
53. S.S. Zhan, K. Beyreuther, H.P. Schmitt, Quantitative assessment of the synaptophysin immuno-reactivity of the cortical neuropil in various neurodegenerative disorders with dementia, Dementia 4 (1993) 66-74.