-
1
-
-
0034697846
-
Identification of a novel FGF, FGF-21, preferentially expressed in the liver
-
DOI 10.1016/S0167-4781(00)00067-1, PII S0167478100000671
-
Nishimura, T., Nakatake, Y., Konishi, M., and Itoh, N. (2000) Identification of a novel FGF, FGF-21, preferentially expressed in the liver. Biochim. Biophys. Acta 1492, 203-206 (Pubitemid 30349198)
-
(2000)
Biochimica et Biophysica Acta - Gene Structure and Expression
, vol.1492
, Issue.1
, pp. 203-206
-
-
Nishimura, T.1
Nakatake, Y.2
Konishi, M.3
Itoh, N.4
-
2
-
-
20444435873
-
FGF-21 as a novel metabolic regulator
-
DOI 10.1172/JCI23606
-
Kharitonenkov, A., Shiyanova, T. L., Koester, A., Ford, A. M., Micanovic, R., Galbreath, E. J., Sandusky, G. E., Hammond, L. J., Moyers, J. S., Owens, R. A., Gromada, J., Brozinick, J. T., Hawkins, E. D., Wroblewski, V. J., Li, D. S., Mehrbod, F., Jaskunas, S. R., and Shanafelt, A. B. (2005) FGF-21 as a novel metabolic regulator. J. Clin. Invest. 115, 1627-1635 (Pubitemid 40814671)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.6
, pp. 1627-1635
-
-
Kharitonenkov, A.1
Shiyanova, T.L.2
Koester, A.3
Ford, A.M.4
Micanovic, R.5
Galbreath, E.J.6
Sandusky, G.E.7
Hammond, L.J.8
Moyers, J.S.9
Owens, R.A.10
Gromada, J.11
Brozinick, J.T.12
Hawkins, E.D.13
Wroblewski, V.J.14
Li, D.-S.15
Mehrbod, F.16
Jaskunas, S.R.17
Shanafelt, A.B.18
-
3
-
-
34249686631
-
Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21
-
DOI 10.1016/j.cmet.2007.05.003, PII S1550413107001301
-
Inagaki, T., Dutchak, P., Zhao, G., Ding, X., Gautron, L., Parameswara, V., Li, Y., Goetz, R., Mohammadi, M., Esser, V., Elmquist, J. K., Gerard, R. D., Burgess, S. C., Hammer, R. E., Mangelsdorf, D. J., and Kliewer, S. A. (2007) Endocrine regulation of the fasting response by PPARα-mediated induction of fibroblast growth factor 21. Cell Metab. 5, 415-425 (Pubitemid 46825496)
-
(2007)
Cell Metabolism
, vol.5
, Issue.6
, pp. 415-425
-
-
Inagaki, T.1
Dutchak, P.2
Zhao, G.3
Ding, X.4
Gautron, L.5
Parameswara, V.6
Li, Y.7
Goetz, R.8
Mohammadi, M.9
Esser, V.10
Elmquist, J.K.11
Gerard, R.D.12
Burgess, S.C.13
Hammer, R.E.14
Mangelsdorf, D.J.15
Kliewer, S.A.16
-
4
-
-
48349127924
-
The circulating metabolic regulator FGF21 is induced by prolonged fasting and PPARα activation in man
-
Gälman, C., Lundåsen, T., Kharitonenkov, A., Bina, H. A., Eriksson, M., Hafström, I., Dahlin, M., Amark, P., Angelin, B., and Rudling, M. (2008) The circulating metabolic regulator FGF21 is induced by prolonged fasting and PPARα activation in man. Cell Metab. 8, 169-174
-
(2008)
Cell Metab.
, vol.8
, pp. 169-174
-
-
Gälman, C.1
Lundåsen, T.2
Kharitonenkov, A.3
Bina, H.A.4
Eriksson, M.5
Hafström, I.6
Dahlin, M.7
Amark, P.8
Angelin, B.9
Rudling, M.10
-
5
-
-
34249677947
-
FGF21. A missing link in the biology of fasting
-
Reitman, M. L. (2007) FGF21. A missing link in the biology of fasting. Cell Metab. 5, 405-407
-
(2007)
Cell Metab.
, vol.5
, pp. 405-407
-
-
Reitman, M.L.1
-
6
-
-
84860341324
-
Role of fibroblast growth factor 21 (FGF21) in undernutrition-related attenuation of growth in mice
-
Kubicky, R. A., Wu, S., Kharitonenkov, A., De Luca, F. (2012) Role of fibroblast growth factor 21 (FGF21) in undernutrition-related attenuation of growth in mice. Endocrinology 153, 2287-2295
-
(2012)
Endocrinology
, vol.153
, pp. 2287-2295
-
-
Kubicky, R.A.1
Wu, S.2
Kharitonenkov, A.3
De Luca, F.4
-
7
-
-
45649085226
-
Inhibition of growth hormone signaling by the fasting-induced hormone FGF21
-
Inagaki, T., Lin, V. Y., Goetz, R., Mohammadi, M., Mangelsdorf, D. J., and Kliewer, S. A. (2008) Inhibition of growth hormone signaling by the fasting-induced hormone FGF21. Cell Metab. 8, 77-83
-
(2008)
Cell Metab.
, vol.8
, pp. 77-83
-
-
Inagaki, T.1
Lin, V.Y.2
Goetz, R.3
Mohammadi, M.4
Mangelsdorf, D.J.5
Kliewer, S.A.6
-
8
-
-
74049108945
-
Fibroblast growth factor 21. From pharmacology to physiology
-
Kliewer, S. A., and Mangelsdorf, D. J. (2010) Fibroblast growth factor 21. From pharmacology to physiology. Am. J. Clin. Nutr. 91, 254S-257S
-
(2010)
Am. J. Clin. Nutr.
, vol.91
-
-
Kliewer, S.A.1
Mangelsdorf, D.J.2
-
9
-
-
39149091423
-
FGF-21/FGF-21 receptor interaction and activation is determined by βKlotho
-
DOI 10.1002/jcp.21357
-
Kharitonenkov, A., Dunbar, J. D., Bina, H. A., Bright, S., Moyers, J. S., Zhang, C., Ding, L., Micanovic, R., Mehrbod, S. F., Knierman, M. D., Hale, J. E., Coskun, T., and Shanafelt, A. B. (2008) FGF-21/FGF-21 receptor interaction and activation is determined by β-klotho. J. Cell Physiol. 215, 1-7 (Pubitemid 351363185)
-
(2008)
Journal of Cellular Physiology
, vol.215
, Issue.1
, pp. 1-7
-
-
Kharitonenkov, A.1
Dunbar, J.D.2
Bina, H.A.3
Bright, S.4
Moyers, J.S.5
Zhang, C.6
Ding, L.7
Micanovic, R.8
Mehrbod, S.F.9
Knierman, M.D.10
Hale, J.E.11
Coskun, T.12
Shanafelt, A.B.13
-
10
-
-
34249697012
-
βKlotho is required for metabolic activity of fibroblast growth factor 21
-
DOI 10.1073/pnas.0701600104
-
Ogawa, Y., Kurosu, H., Yamamoto, M., Nandi, A., Rosenblatt, K. P., Goetz, R., Eliseenkova, A. V., Mohammadi, M., and Kuro-o, M. (2007) β-Klotho is required for metabolic activity of fibroblast growth factor 21. Proc. Natl. Acad. Sci. U.S.A. 104, 7432-7437 (Pubitemid 47185923)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.18
, pp. 7432-7437
-
-
Ogawa, Y.1
Kurosu, H.2
Yamamoto, M.3
Nandi, A.4
Rosenblatt, K.P.5
Goetz, R.6
Eliseenkova, A.V.7
Mohammadi, M.8
Kuro-O, M.9
-
11
-
-
41649109108
-
βklotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c
-
DOI 10.1210/me.2007-0313
-
Suzuki, M., Uehara, Y., Motomura-Matsuzaka, K., Oki, J., Koyama, Y., Kimura, M., Asada, M., Komi-Kuramochi, A., Oka, S., and Imamura, T. (2008) β-Klotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c. Mol. Endocrinol. 22, 1006-1014 (Pubitemid 351482834)
-
(2008)
Molecular Endocrinology
, vol.22
, Issue.4
, pp. 1006-1014
-
-
Suzuki, M.1
Uehara, Y.2
Motomura-Matsuzaka, K.3
Oki, J.4
Koyama, Y.5
Kimura, M.6
Asada, M.7
Komi-Kuramochi, A.8
Oka, S.9
Imamura, T.10
-
12
-
-
34848869695
-
Tissue-specific expression of βklotho and Fibroblast Growth Factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21
-
DOI 10.1074/jbc.M704165200
-
Kurosu, H., Choi, M., Ogawa, Y., Dickson, A. S., Goetz, R., Eliseenkova, A. V., Mohammadi, M., Rosenblatt, K. P., Kliewer, S. A., and Kuro-o, M. (2007) Tissue-specific expression of β-klotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21. J. Biol. Chem. 282, 26687-26695 (Pubitemid 47501965)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.37
, pp. 26687-26695
-
-
Kurosu, H.1
Choi, M.2
Ogawa, Y.3
Dickson, A.S.4
Goetz, R.5
Eliseenkova, A.V.6
Mohammadi, M.7
Rosenblatt, K.P.8
Kliewer, S.A.9
Kuro-O, M.10
-
13
-
-
77957376253
-
Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse
-
Fon Tacer, K., Bookout, A. L., Ding, X., Kurosu, H., John, G. B., Wang, L., Goetz, R., Mohammadi, M., Kuro-o, M., Mangelsdorf, D. J., and Kliewer, S. A. (2010) Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse. Mol. Endocrinol. 24, 2050-2064
-
(2010)
Mol. Endocrinol.
, vol.24
, pp. 2050-2064
-
-
Fon Tacer, K.1
Bookout, A.L.2
Ding, X.3
Kurosu, H.4
John, G.B.5
Wang, L.6
Goetz, R.7
Mohammadi, M.8
Kuro-o, M.9
Mangelsdorf, D.J.10
Kliewer, S.A.11
-
14
-
-
44949231424
-
T method
-
DOI 10.1038/nprot.2008.73, PII NPROT.2008.73
-
Schmittgen, T. D., and Livak, K. J. (2008) Analyzing real-time PCR data by the comparative C(T) method. Nat. Protoc. 3, 1101-1108 (Pubitemid 351818697)
-
(2008)
Nature Protocols
, vol.3
, Issue.6
, pp. 1101-1108
-
-
Schmittgen, T.D.1
Livak, K.J.2
-
15
-
-
0034489210
-
Insulin regulation of human hepatic growth hormone receptors: Divergent effects on biosynthesis and surface translocation
-
DOI 10.1210/jc.85.12.4712
-
Leung, K. C., Doyle, N., Ballesteros, M., Waters, M. J., and Ho, K. K. (2000) Insulin regulation of human hepatic growth hormone receptors. Divergent effects on biosynthesis and surface translocation. J. Clin. Endocrinol. Metab. 85, 4712-4720 (Pubitemid 32157657)
-
(2000)
Journal of Clinical Endocrinology and Metabolism
, vol.85
, Issue.12
, pp. 4712-4720
-
-
Leung, K.-C.1
Doyle, N.2
Ballesteros, M.3
Waters, M.J.4
Ho, K.K.Y.5
-
16
-
-
72849130864
-
LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice
-
Touvier, T., Conte-Auriol, F., Briand, O., Cudejko, C., Paumelle, R., Caron, S., Baugé, E., Rouillé, Y., Salles, J. P., Staels, B., and Bailleul, B. (2009) LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice. J. Clin. Invest. 119, 3830-3838
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3830-3838
-
-
Touvier, T.1
Conte-Auriol, F.2
Briand, O.3
Cudejko, C.4
Paumelle, R.5
Caron, S.6
Baugé, E.7
Rouillé, Y.8
Salles, J.P.9
Staels, B.10
Bailleul, B.11
-
17
-
-
0028067659
-
Mechanism of longitudinal bone growth and its regulation by growth plate chondrocytes
-
Hunziker, E. B. (1994) Mechanism of longitudinal bone growth and its regulation by growth plate chondrocytes. Microsc. Res. Tech. 28, 505-519
-
(1994)
Microsc. Res. Tech.
, vol.28
, pp. 505-519
-
-
Hunziker, E.B.1
-
18
-
-
0023552017
-
Morphologic stages of the terminal hypertrophic chondrocyte of growth plate cartilage
-
Farnum, C. E., and Wilshan, N. J. (1987) Morphologic stages of terminal hypertrophic chondrocyte of growth plate cartilage. Anat. Rec. 219, 221-232 (Pubitemid 18046585)
-
(1987)
Anatomical Record
, vol.219
, Issue.3
, pp. 221-232
-
-
Farnum, C.E.1
Wilsman, N.J.2
-
19
-
-
0029051176
-
Microvascular pattern in the metaphysis during bone growth
-
Aharinejad, S., Marks, S. C., Jr., Böck, P., MacKay, C. A., Larson E. K., Tahamtani A., Mason-Savas A, and Firbas, W. (1995) Microvascular pattern in the metaphysis during bone growth. Anat. Rec. 242, 111-122
-
(1995)
Anat. Rec.
, vol.242
, pp. 111-122
-
-
Aharinejad, S.1
Marks Jr., S.C.2
Böck, P.3
MacKay, C.A.4
Larson, E.K.5
Tahamtani, A.6
Mason-Savas, A.7
Firbas, W.8
-
20
-
-
0032996450
-
Control of bone growth by fibroblast growth factors
-
DOI 10.1016/S1043-2760(98)00120-9, PII S1043276098001209
-
De Luca, F., and Baron, J. (1999) Control of bone growth by fibroblast growth factors. Trends. Endocrinol. Metab. 10, 61-65 (Pubitemid 29287824)
-
(1999)
Trends in Endocrinology and Metabolism
, vol.10
, Issue.2
, pp. 61-65
-
-
De Luca, F.1
Baron, J.2
-
21
-
-
69849107415
-
FGFs in endochondral skeletal development
-
Horton, W. A., and Degnin, C. R. (2009) FGFs in endochondral skeletal development. Trends. Endocrinol. Metab. 20, 341-348
-
(2009)
Trends. Endocrinol. Metab.
, vol.20
, pp. 341-348
-
-
Horton, W.A.1
Degnin, C.R.2
-
22
-
-
33846566729
-
Fibroblast growth factor expression in the postnatal growth plate
-
DOI 10.1016/j.bone.2006.10.013, PII S8756328206007897
-
Lazarus, J. E., Hegde, A., Andrade, A. C., Nilsson, O., and Baron, J. (2007) Fibroblast growth factor expression in the postnatal growth plate. Bone 40, 577-586 (Pubitemid 46187233)
-
(2007)
Bone
, vol.40
, Issue.3
, pp. 577-586
-
-
Lazarus, J.E.1
Hegde, A.2
Andrade, A.C.3
Nilsson, O.4
Baron, J.5
-
23
-
-
0029917507
-
Fibroblast growth factor receptor 3 is a negative regulator of bone growth
-
DOI 10.1016/S0092-8674(00)81069-7
-
Deng, C., Wynshaw-Boris, A., Zhou, F., Kuo, A., and Leder, P. (1996) Fibroblast growth factor receptor 3 is a negative regulator of bone growth. Cell 84, 911-921 (Pubitemid 26106860)
-
(1996)
Cell
, vol.84
, Issue.6
, pp. 911-921
-
-
Deng, C.1
Wynshaw-Boris, A.2
Zhou, F.3
Kuo, A.4
Leder, P.5
-
24
-
-
19944430581
-
Mutations that cause osteoglophonic dysplasia define novel roles for FGFR1 in bone elongation
-
DOI 10.1086/427956
-
White, K. E., Cabral, J. M., Davis, S. I., Fishburn, T., Evans, W. E., Ichikawa, S., Fields, J., Yu, X., Shaw, N. J., McLellan, N. J., McKeown, C., Fitzpatrick, D., Yu, K., Ornitz, D. M., and Econs, M. J. (2005) Mutations that cause osteoglophonic dysplasia define novel roles for FGFR1 in bone elongation. Am. J. Hum. Genet. 76, 361-367 (Pubitemid 40129563)
-
(2005)
American Journal of Human Genetics
, vol.76
, Issue.2
, pp. 361-367
-
-
White, K.E.1
Cabral, J.M.2
Davis, S.I.3
Fishburn, T.4
Evans, W.E.5
Ichikawa, S.6
Fields, J.7
Yu, X.8
Shaw, N.J.9
McLellan, N.J.10
McKeown, C.11
FitzPatrick, D.12
Yu, K.13
Ornitz, D.M.14
Econs, M.J.15
-
25
-
-
0034772675
-
Differential regulation of endochondral bone growth and joint development by FGFR1 and FGFR3 tyrosine kinase domains
-
Wang, Q., Green, R. P., Zhao, G., and Ornitz, D. M. (2001) Differential regulation of endochondral bone growth and joint development by FGFR1 and FGFR3-tyrosine kinase domains. Development 128, 3867-3876 (Pubitemid 32998934)
-
(2001)
Development
, vol.128
, Issue.19
, pp. 3867-3876
-
-
Wang, Q.1
Green, R.P.2
Zhao, G.3
Ornitz, D.M.4
-
26
-
-
0038782306
-
Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth
-
DOI 10.1242/dev.00491
-
Yu, K., Xu, J., Liu, Z., Sosic, D., Shao, J., Olson, E. N., Towler, D. A., and Ornitz, D. M. (2003) Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development 130, 3063-3074 (Pubitemid 36857252)
-
(2003)
Development
, vol.130
, Issue.13
, pp. 3063-3074
-
-
Yu, K.1
Xu, J.2
Liu, Z.3
Sosic, D.4
Shao, J.5
Olson, E.N.6
Towler, D.A.7
Ornitz, D.M.8
-
27
-
-
0031700905
-
FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung
-
Weinstein, M., Xu, X., Ohyama, K., and Deng, C. X. (1998) FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung. Development 125, 3615-3623 (Pubitemid 28469962)
-
(1998)
Development
, vol.125
, Issue.18
, pp. 3615-3623
-
-
Weinstein, M.1
Xu, X.2
Ohyama, K.3
Deng, C.-X.4
-
28
-
-
0028880515
-
Abnormal bone growth and selective translational regulation in basic fibroblast growth factor (FGF-2) transgenic mice
-
Coffin, J. D., Florkiewicz, R. Z., Neumann, J., Mort-Hopkins, T., Dorn, G. W., 2nd, Lightfoot, P., German, R., Howles, P. N., Kier, A., and O'Toole, B. A. (1995) Abnormal bone growth and selective translational regulation in basic fibroblast growth factor (FGF-2) transgenic mice. Mol. Biol. Cell 6, 1861-1873
-
(1995)
Mol. Biol. Cell
, vol.6
, pp. 1861-1873
-
-
Coffin, J.D.1
Florkiewicz, R.Z.2
Neumann, J.3
Mort-Hopkins, T.4
Dorn II, G.W.5
Lightfoot, P.6
German, R.7
Howles, P.N.8
Kier, A.9
O'Toole, B.A.10
-
29
-
-
0032759872
-
Skeletal dysplasia and defective chondrocyte differentiation by targeted overexpression of fibroblast growth factor 9 in transgenic mice
-
DOI 10.1359/jbmr.1999.14.11.1909
-
Garofalo, S., Kliger-Spatz, M., Cooke, J. L., Wolstin, O., Lunstrum, G. P., Moshkovitz, S. M., Horton, W. A., and Yayon, A. (1999) Skeletal dysplasia and defective chondrocyte differentiation by targeted overexpression of fibroblast growth factor 9 in transgenic mice. J. Bone. Miner. Res. 14, 1909-1915 (Pubitemid 29521786)
-
(1999)
Journal of Bone and Mineral Research
, vol.14
, Issue.11
, pp. 1909-1915
-
-
Garofalo, S.1
Kliger-Spatz, M.2
Cooke, J.L.3
Wolstin, O.4
Lunstrum, G.P.5
Moshkovitz, S.M.6
Horton, W.A.7
Yayon, A.8
-
30
-
-
0036203355
-
Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18
-
DOI 10.1101/gad.965602
-
Liu, Z., Xu, J., Colvin, J. S., and Ornitz, D. M. (2002) Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18. Genes Dev. 16, 859-869 (Pubitemid 34280109)
-
(2002)
Genes and Development
, vol.16
, Issue.7
, pp. 859-869
-
-
Liu, Z.1
Xu, J.2
Colvin, J.S.3
Ornitz, D.M.4
-
31
-
-
0036205735
-
FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis
-
DOI 10.1101/gad.965702
-
Ohbayashi, N., Shibayama, M., Kurotaki, Y., Imanishi, M., Fujimori, T., Itoh, N., Takada, S. (2002) FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev. 16, 870-879 (Pubitemid 34280110)
-
(2002)
Genes and Development
, vol.16
, Issue.7
, pp. 870-879
-
-
Ohbayashi, N.1
Shibayama, M.2
Kurotaki, Y.3
Imanishi, M.4
Fujimori, T.5
Itoh, N.6
Takada, S.7
-
32
-
-
70350093621
-
Fibroblast growth factor 21 reduces the severity of cerulein-induced pancreatitis in mice
-
Johnson, C. L., Weston, J. Y., Chadi, S. A., Fazio, E. N., Huff, M. W., Kharitonenkov, A., Köester, A., and Pin, C. L. (2009) Fibroblast growth factor 21 reduces the severity of cerulein-induced pancreatitis in mice. Gastroenterology 137, 1795-1804
-
(2009)
Gastroenterology
, vol.137
, pp. 1795-1804
-
-
Johnson, C.L.1
Weston, J.Y.2
Chadi, S.A.3
Fazio, E.N.4
Huff, M.W.5
Kharitonenkov, A.6
Köester, A.7
Pin, C.L.8
-
33
-
-
78049297991
-
Obesity is a fibroblast growth factor 21 (FGF21)-resistant state
-
Fisher, F. M., Chui, P. C., Antonellis, P. J., Bina, H. A., Kharitonenkov, A., Flier, J. S., and Maratos-Flier, E. (2010) Obesity is a fibroblast growth factor 21 (FGF21)-resistant state. Diabetes 59, 2781-2789
-
(2010)
Diabetes
, vol.59
, pp. 2781-2789
-
-
Fisher, F.M.1
Chui, P.C.2
Antonellis, P.J.3
Bina, H.A.4
Kharitonenkov, A.5
Flier, J.S.6
Maratos-Flier, E.7
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