메뉴 건너뛰기




Volumn 12, Issue 15, 2013, Pages 2376-2383

Genetic control of quiescence in hematopoietic stem cells

Author keywords

G0S2; Hematopoietic stem cells; Quiescence

Indexed keywords

ANGIOPOIETIN 1; BETA CATENIN; CHEMOKINE RECEPTOR CXCR4; INTEGRIN RECEPTOR; NUCLEOLIN; PROTEIN; STEM CELL FACTOR; STROMAL CELL DERIVED FACTOR 1; TRANSFORMING GROWTH FACTOR BETA;

EID: 84881504235     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.25416     Document Type: Review
Times cited : (22)

References (83)
  • 1
    • 44349096923 scopus 로고    scopus 로고
    • Stem cell niche: Microenvironment and beyond
    • PMID:18272517
    • Zhang J, Li L. Stem cell niche: microenvironment and beyond. J Biol Chem 2008; 283:9499-503; PMID:18272517; http://dx.doi.org/10.1074/jbc. R700043200
    • (2008) J Biol Chem , vol.283 , pp. 9499-9503
    • Zhang, J.1    Li, L.2
  • 2
    • 41149109622 scopus 로고    scopus 로고
    • Uncertainty in the niches that maintain haematopoietic stem cells
    • PMID:18323850
    • Kiel MJ, Morrison SJ. Uncertainty in the niches that maintain haematopoietic stem cells. Nat Rev Immunol 2008; 8:290-301; PMID:18323850; http://dx.doi.org/10.1038/nri2279
    • (2008) Nat Rev Immunol , vol.8 , pp. 290-301
    • Kiel, M.J.1    Morrison, S.J.2
  • 3
    • 33845467828 scopus 로고    scopus 로고
    • Maintaining hematopoietic stem cells in the vascular niche
    • PMID:17174928
    • Kiel MJ, Morrison SJ. Maintaining hematopoietic stem cells in the vascular niche. Immunity 2006; 25:862-4; PMID:17174928; http://dx.doi.org/10. 1016/j.immuni.2006.11.005
    • (2006) Immunity , vol.25 , pp. 862-864
    • Kiel, M.J.1    Morrison, S.J.2
  • 4
    • 33646435309 scopus 로고    scopus 로고
    • The stem cell niches in bone
    • PMID:16670760
    • Yin T, Li L. The stem cell niches in bone. J Clin Invest 2006; 116:1195-201; PMID:16670760; http://dx.doi.org/10.1172/JCI28568
    • (2006) J Clin Invest , vol.116 , pp. 1195-1201
    • Yin, T.1    Li, L.2
  • 5
    • 0242363225 scopus 로고    scopus 로고
    • Identification of the haematopoietic stem cell niche and control of the niche size
    • PMID:14574412
    • Zhang J, Niu C, Ye L, Huang H, He X, Tong WG, et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 2003; 425:836-41; PMID:14574412; http://dx.doi.org/10.1038/nature02041
    • (2003) Nature , vol.425 , pp. 836-841
    • Zhang, J.1    Niu, C.2    Ye, L.3    Huang, H.4    He, X.5    Tong, W.G.6
  • 6
    • 0242268524 scopus 로고    scopus 로고
    • Osteoblastic cells regulate the haematopoietic stem cell niche
    • PMID:14574413
    • Calvi LM, Adams GB, Weibrecht KW, Weber JM, Olson DP, Knight MC, et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 2003; 425:841-6; PMID:14574413; http://dx.doi.org/10.1038/nature02040
    • (2003) Nature , vol.425 , pp. 841-846
    • Calvi, L.M.1    Adams, G.B.2    Weibrecht, K.W.3    Weber, J.M.4    Olson, D.P.5    Knight, M.C.6
  • 7
    • 26844520899 scopus 로고    scopus 로고
    • The bone marrow vascular niche: Home of HSC differentiation and mobilization
    • PMID:16174874
    • Kopp HG, Avecilla ST, Hooper AT, Rafii S. The bone marrow vascular niche: home of HSC differentiation and mobilization. Physiology (Bethesda) 2005; 20:349-56; PMID:16174874; http://dx.doi.org/10.1152/physiol.00025.2005
    • (2005) Physiology (Bethesda) , vol.20 , pp. 349-356
    • Kopp, H.G.1    Avecilla, S.T.2    Hooper, A.T.3    Rafii, S.4
  • 8
    • 84856147560 scopus 로고    scopus 로고
    • Endothelial and perivascular cells maintain haematopoietic stem cells
    • PMID:22281595
    • Ding L, Saunders TL, Enikolopov G, Morrison SJ. Endothelial and perivascular cells maintain haematopoietic stem cells. Nature 2012; 481:457-62; PMID:22281595; http://dx.doi.org/10.1038/nature10783
    • (2012) Nature , vol.481 , pp. 457-462
    • Ding, L.1    Saunders, T.L.2    Enikolopov, G.3    Morrison, S.J.4
  • 9
    • 77953462161 scopus 로고    scopus 로고
    • Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection
    • PMID:20535209
    • Baldridge MT, King KY, Boles NC, Weksberg DC, Goodell MA. Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection. Nature 2010; 465:793-7; PMID:20535209; http://dx.doi.org/10.1038/ nature09135
    • (2010) Nature , vol.465 , pp. 793-797
    • Baldridge, M.T.1    King, K.Y.2    Boles, N.C.3    Weksberg, D.C.4    Goodell, M.A.5
  • 10
    • 66149115277 scopus 로고    scopus 로고
    • IFNalpha activates dormant haematopoietic stem cells in vivo
    • PMID:19212321
    • Essers MA, Offner S, Blanco-Bose WE, Waibler Z, Kalinke U, Duchosal MA, et al. IFNalpha activates dormant haematopoietic stem cells in vivo. Nature 2009; 458:904-8; PMID:19212321; http://dx.doi.org/10.1038/nature07815
    • (2009) Nature , vol.458 , pp. 904-908
    • Essers, M.A.1    Offner, S.2    Blanco-Bose, W.E.3    Waibler, Z.4    Kalinke, U.5    Duchosal, M.A.6
  • 11
    • 84877607466 scopus 로고    scopus 로고
    • TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy
    • PMID:23440043
    • Brenet F, Kermani P, Spektor R, Rafii S, Scandura JM. TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy. J Exp Med 2013; 210:623-39; PMID:23440043; http://dx.doi.org/10.1084/jem.20121610
    • (2013) J Exp Med , vol.210 , pp. 623-639
    • Brenet, F.1    Kermani, P.2    Spektor, R.3    Rafii, S.4    Scandura, J.M.5
  • 12
    • 33749000855 scopus 로고    scopus 로고
    • Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration
    • PMID:16968775
    • Trowbridge JJ, Scott MP, Bhatia M. Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration. Proc Natl Acad Sci U S A 2006; 103:14134-9; PMID:16968775; http://dx.doi. org/10.1073/pnas. 0604568103
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 14134-14139
    • Trowbridge, J.J.1    Scott, M.P.2    Bhatia, M.3
  • 13
    • 0034629129 scopus 로고    scopus 로고
    • Hematopoietic stem cell quiescence maintained by p21cip1/waf1
    • PMID:10710306
    • Cheng T, Rodrigues N, Shen H, Yang Y, Dombkowski D, Sykes M, et al. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science 2000; 287:1804-8; PMID:10710306; http://dx.doi.org/10.1126/science.287.5459.1804
    • (2000) Science , vol.287 , pp. 1804-1808
    • Cheng, T.1    Rodrigues, N.2    Shen, H.3    Yang, Y.4    Dombkowski, D.5    Sykes, M.6
  • 14
    • 2342601849 scopus 로고    scopus 로고
    • In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C
    • PMID:15122268
    • Yuan Y, Shen H, Franklin DS, Scadden DT, Cheng T. In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C. Nat Cell Biol 2004; 6:436-42; PMID:15122268; http://dx.doi.org/10.1038/ncb1126
    • (2004) Nat Cell Biol , vol.6 , pp. 436-442
    • Yuan, Y.1    Shen, H.2    Franklin, D.S.3    Scadden, D.T.4    Cheng, T.5
  • 15
    • 80052289298 scopus 로고    scopus 로고
    • P57 is required for quiescence and maintenance of adult hematopoietic stem cells
    • PMID:21885021
    • Matsumoto A, Takeishi S, Kanie T, Susaki E, Onoyama I, Tateishi Y, et al. p57 is required for quiescence and maintenance of adult hematopoietic stem cells. Cell Stem Cell 2011; 9:262-71; PMID:21885021; http://dx.doi.org/10.1016/ j. stem.2011.06.014
    • (2011) Cell Stem Cell , vol.9 , pp. 262-271
    • Matsumoto, A.1    Takeishi, S.2    Kanie, T.3    Susaki, E.4    Onoyama, I.5    Tateishi, Y.6
  • 16
    • 80052281899 scopus 로고    scopus 로고
    • P57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70
    • PMID:21885020
    • Zou P, Yoshihara H, Hosokawa K, Tai I, Shinmyozu K, Tsukahara F, et al. p57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70. Cell Stem Cell 2011; 9:247-61; PMID:21885020; http://dx.doi.org/10.1016/j.stem.2011.07.003
    • (2011) Cell Stem Cell , vol.9 , pp. 247-261
    • Zou, P.1    Yoshihara, H.2    Hosokawa, K.3    Tai, I.4    Shinmyozu, K.5    Tsukahara, F.6
  • 17
    • 8844250116 scopus 로고    scopus 로고
    • Molecular signatures of proliferation and quiescence in hematopoietic stem cells
    • PMID:15459755
    • Venezia TA, Merchant AA, Ramos CA, Whitehouse NL, Young AS, Shaw CA, et al. Molecular signatures of proliferation and quiescence in hematopoietic stem cells. PLoS Biol 2004; 2:e301; PMID:15459755; http://dx.doi.org/10.1371/journal. pbio.0020301
    • (2004) PLoS Biol , vol.2
    • Venezia, T.A.1    Merchant, A.A.2    Ramos, C.A.3    Whitehouse, N.L.4    Young, A.S.5    Shaw, C.A.6
  • 18
    • 63249095562 scopus 로고    scopus 로고
    • JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal
    • PMID:19345332
    • Santaguida M, Schepers K, King B, Sabnis AJ, Forsberg EC, Attema JL, et al. JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal. Cancer Cell 2009; 15:341-52; PMID:19345332; http://dx.doi.org/10.1016/j. ccr.2009.02.016
    • (2009) Cancer Cell , vol.15 , pp. 341-352
    • Santaguida, M.1    Schepers, K.2    King, B.3    Sabnis, A.J.4    Forsberg, E.C.5    Attema, J.L.6
  • 19
    • 42649142267 scopus 로고    scopus 로고
    • Pbx1 regulates self-renewal of long-term hematopoietic stem cells by maintaining their quiescence
    • PMID:18462698
    • Ficara F, Murphy MJ, Lin M, Cleary ML. Pbx1 regulates self-renewal of long-term hematopoietic stem cells by maintaining their quiescence. Cell Stem Cell 2008; 2:484-96; PMID:18462698; http://dx.doi.org/10.1016/j.stem.2008.03.004
    • (2008) Cell Stem Cell , vol.2 , pp. 484-496
    • Ficara, F.1    Murphy, M.J.2    Lin, M.3    Cleary, M.L.4
  • 20
    • 33846419112 scopus 로고    scopus 로고
    • FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
    • PMID:17254970
    • Tothova Z, Kollipara R, Huntly BJ, Lee BH, Castrillon DH, Cullen DE, et al. FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell 2007; 128:325-39; PMID:17254970; http://dx.doi.org/10.1016/j. cell.2007.01.003
    • (2007) Cell , vol.128 , pp. 325-339
    • Tothova, Z.1    Kollipara, R.2    Huntly, B.J.3    Lee, B.H.4    Castrillon, D.H.5    Cullen, D.E.6
  • 21
    • 34249882777 scopus 로고    scopus 로고
    • Foxo3a is essential for maintenance of the hematopoietic stem cell pool
    • PMID:18371339
    • Miyamoto K, Araki KY, Naka K, Arai F, Takubo K, Yamazaki S, et al. Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cell 2007; 1:101-12; PMID:18371339; http://dx.doi.org/10.1016/j.stem.2007.02.001
    • (2007) Cell Stem Cell , vol.1 , pp. 101-112
    • Miyamoto, K.1    Araki, K.Y.2    Naka, K.3    Arai, F.4    Takubo, K.5    Yamazaki, S.6
  • 22
    • 78649880379 scopus 로고    scopus 로고
    • The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells
    • PMID:21076412
    • Sirin O, Lukov GL, Mao R, Conneely OM, Goodell MA. The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells. Nat Cell Biol 2010; 12:1213-9; PMID:21076412; http://dx.doi.org/10.1038/ncb2125
    • (2010) Nat Cell Biol , vol.12 , pp. 1213-1219
    • Sirin, O.1    Lukov, G.L.2    Mao, R.3    Conneely, O.M.4    Goodell, M.A.5
  • 23
    • 33644819269 scopus 로고    scopus 로고
    • The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells
    • PMID:16530702
    • Lacorazza HD, Yamada T, Liu Y, Miyata Y, Sivina M, Nunes J, et al. The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells. Cancer Cell 2006; 9:175-87; PMID:16530702; http://dx.doi.org/10.1016/j.ccr.2006.02.017
    • (2006) Cancer Cell , vol.9 , pp. 175-187
    • Lacorazza, H.D.1    Yamada, T.2    Liu, Y.3    Miyata, Y.4    Sivina, M.5    Nunes, J.6
  • 24
    • 58049216794 scopus 로고    scopus 로고
    • P53 regulates hematopoietic stem cell quiescence
    • PMID:19128791
    • Liu Y, Elf SE, Miyata Y, Sashida G, Liu Y, Huang G, et al. p53 regulates hematopoietic stem cell quiescence. Cell Stem Cell 2009; 4:37-48; PMID:19128791; http://dx.doi.org/10.1016/j.stem.2008.11.006
    • (2009) Cell Stem Cell , vol.4 , pp. 37-48
    • Liu, Y.1    Elf, S.E.2    Miyata, Y.3    Sashida, G.4    Liu, Y.5    Huang, G.6
  • 25
    • 78049499084 scopus 로고    scopus 로고
    • Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity
    • PMID:21040902
    • Abbas HA, Maccio DR, Coskun S, Jackson JG, Hazen AL, Sills TM, et al. Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity. Cell Stem Cell 2010; 7:606-17; PMID:21040902; http://dx.doi.org/10.1016/j.stem.2010.09.013
    • (2010) Cell Stem Cell , vol.7 , pp. 606-617
    • Abbas, H.A.1    MacCio, D.R.2    Coskun, S.3    Jackson, J.G.4    Hazen, A.L.5    Sills, T.M.6
  • 27
    • 44449104279 scopus 로고    scopus 로고
    • AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis
    • PMID:18354160
    • Ichikawa M, Goyama S, Asai T, Kawazu M, Nakagawa M, Takeshita M, et al. AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis. J Immunol 2008; 180:4402-8; PMID:18354160
    • (2008) J Immunol , vol.180 , pp. 4402-4408
    • Ichikawa, M.1    Goyama, S.2    Asai, T.3    Kawazu, M.4    Nakagawa, M.5    Takeshita, M.6
  • 28
    • 41449118699 scopus 로고    scopus 로고
    • The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells
    • PMID:18397757
    • Min IM, Pietramaggiori G, Kim FS, Passegué E, Stevenson KE, Wagers AJ. The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells. Cell Stem Cell 2008; 2:380-91; PMID:18397757; http://dx.doi.org/10.1016/j.stem.2008.01.015
    • (2008) Cell Stem Cell , vol.2 , pp. 380-391
    • Min, I.M.1    Pietramaggiori, G.2    Kim, F.S.3    Passegué, E.4    Stevenson, K.E.5    Wagers, A.J.6
  • 29
    • 66549086623 scopus 로고    scopus 로고
    • Conditional deletion of STAT5 in adult mouse hematopoietic stem cells causes loss of quiescence and permits efficient nonablative stem cell replacement
    • PMID:19258595
    • Wang Z, Li G, Tse W, Bunting KD. Conditional deletion of STAT5 in adult mouse hematopoietic stem cells causes loss of quiescence and permits efficient nonablative stem cell replacement. Blood 2009; 113:4856-65; PMID:19258595; http://dx.doi.org/10.1182/blood-2008-09-181107
    • (2009) Blood , vol.113 , pp. 4856-4865
    • Wang, Z.1    Li, G.2    Tse, W.3    Bunting, K.D.4
  • 30
    • 76949085686 scopus 로고    scopus 로고
    • Regulation of hematopoietic stem cell differentiation by a single ubiquitin ligase-substrate complex
    • PMID:20081848
    • Reavie L, Della Gatta G, Crusio K, Aranda-Orgilles B, Buckley SM, Thompson B, et al. Regulation of hematopoietic stem cell differentiation by a single ubiquitin ligase-substrate complex. Nat Immunol 2010; 11:207-15; PMID:20081848; http://dx.doi.org/10.1038/ni.1839
    • (2010) Nat Immunol , vol.11 , pp. 207-215
    • Reavie, L.1    Della Gatta, G.2    Crusio, K.3    Aranda-Orgilles, B.4    Buckley, S.M.5    Thompson, B.6
  • 31
    • 84876434253 scopus 로고    scopus 로고
    • Regulation of c-Myc ubiquitination controls chronic myelogenous leukemia initiation and progression
    • PMID:23518350
    • Reavie L, Buckley SM, Loizou E, Takeishi S, Aranda-Orgilles B, Ndiaye-Lobry D, et al. Regulation of c-Myc ubiquitination controls chronic myelogenous leukemia initiation and progression. Cancer Cell 2013; 23:362-75; PMID:23518350; http://dx.doi.org/10.1016/j.ccr.2013.01.025
    • (2013) Cancer Cell , vol.23 , pp. 362-375
    • Reavie, L.1    Buckley, S.M.2    Loizou, E.3    Takeishi, S.4    Aranda-Orgilles, B.5    Ndiaye-Lobry, D.6
  • 32
    • 84876422526 scopus 로고    scopus 로고
    • Ablation of Fbxw7 eliminates leukemia-initiating cells by preventing quiescence
    • PMID:23518349
    • Takeishi S, Matsumoto A, Onoyama I, Naka K, Hirao A, Nakayama KI. Ablation of Fbxw7 eliminates leukemia-initiating cells by preventing quiescence. Cancer Cell 2013; 23:347-61; PMID:23518349; http://dx.doi.org/10.1016/j.ccr. 2013.01.026
    • (2013) Cancer Cell , vol.23 , pp. 347-361
    • Takeishi, S.1    Matsumoto, A.2    Onoyama, I.3    Naka, K.4    Hirao, A.5    Nakayama, K.I.6
  • 33
    • 78649811793 scopus 로고    scopus 로고
    • Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells
    • PMID:21124450
    • Nakada D, Saunders TL, Morrison SJ. Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells. Nature 2010; 468:653-8; PMID:21124450; http://dx.doi.org/10.1038/nature09571
    • (2010) Nature , vol.468 , pp. 653-658
    • Nakada, D.1    Saunders, T.L.2    Morrison, S.J.3
  • 34
    • 78649851511 scopus 로고    scopus 로고
    • The Lkb1 metabolic sensor maintains haematopoietic stem cell survival
    • PMID:21124451
    • Gurumurthy S, Xie SZ, Alagesan B, Kim J, Yusuf RZ, Saez B, et al. The Lkb1 metabolic sensor maintains haematopoietic stem cell survival. Nature 2010; 468:659-63; PMID:21124451; http://dx.doi.org/10.1038/nature09572
    • (2010) Nature , vol.468 , pp. 659-663
    • Gurumurthy, S.1    Xie, S.Z.2    Alagesan, B.3    Kim, J.4    Yusuf, R.Z.5    Saez, B.6
  • 35
    • 77953283847 scopus 로고    scopus 로고
    • AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species
    • PMID:20354168
    • Juntilla MM, Patil VD, Calamito M, Joshi RP, Birnbaum MJ, Koretzky GA. AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species. Blood 2010; 115:4030-8; PMID:20354168; http://dx.doi.org/10. 1182/blood-2009-09-241000
    • (2010) Blood , vol.115 , pp. 4030-4038
    • Juntilla, M.M.1    Patil, V.D.2    Calamito, M.3    Joshi, R.P.4    Birnbaum, M.J.5    Koretzky, G.A.6
  • 36
    • 53349091768 scopus 로고    scopus 로고
    • TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
    • PMID:18809716
    • Chen C, Liu Y, Liu R, Ikenoue T, Guan KL, Liu Y, et al. TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. J Exp Med 2008; 205:2397-408; PMID:18809716; http://dx.doi.org/10.1084/jem.20081297
    • (2008) J Exp Med , vol.205 , pp. 2397-2408
    • Chen, C.1    Liu, Y.2    Liu, R.3    Ikenoue, T.4    Guan, K.L.5    Liu, Y.6
  • 37
    • 84862891914 scopus 로고    scopus 로고
    • Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: Terminology for TOR-driven aging
    • PMID:22394614
    • Blagosklonny MV. Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging. Aging (Albany NY) 2012; 4:159-65; PMID:22394614
    • (2012) Aging (Albany NY) , vol.4 , pp. 159-165
    • Blagosklonny, M.V.1
  • 38
    • 70450253358 scopus 로고    scopus 로고
    • Cited2 is an essential regulator of adult hematopoietic stem cells
    • PMID:19951693
    • Kranc KR, Schepers H, Rodrigues NP, Bamforth S, Villadsen E, Ferry H, et al. Cited2 is an essential regulator of adult hematopoietic stem cells. Cell Stem Cell 2009; 5:659-65; PMID:19951693; http://dx.doi.org/10.1016/j.stem.2009. 11.001
    • (2009) Cell Stem Cell , vol.5 , pp. 659-665
    • Kranc, K.R.1    Schepers, H.2    Rodrigues, N.P.3    Bamforth, S.4    Villadsen, E.5    Ferry, H.6
  • 39
    • 84863376354 scopus 로고    scopus 로고
    • HIF-1α deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency
    • PMID:22308296
    • Du J, Chen Y, Li Q, Han X, Cheng C, Wang Z, et al. HIF-1α deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency. Blood 2012; 119:2789-98; PMID:22308296; http://dx.doi.org/10.1182/ blood-2011-10-387902
    • (2012) Blood , vol.119 , pp. 2789-2798
    • Du, J.1    Chen, Y.2    Li, Q.3    Han, X.4    Cheng, C.5    Wang, Z.6
  • 40
    • 70149088015 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein regulates hematopoietic stem cell quiescence and mobilization under stress conditions
    • PMID:19625652
    • Jeong M, Piao ZH, Kim MS, Lee SH, Yun S, Sun HN, et al. Thioredoxin-interacting protein regulates hematopoietic stem cell quiescence and mobilization under stress conditions. J Immunol 2009; 183:2495-505; PMID:19625652; http://dx.doi.org/10.4049/jimmunol.0804221
    • (2009) J Immunol , vol.183 , pp. 2495-2505
    • Jeong, M.1    Piao, Z.H.2    Kim, M.S.3    Lee, S.H.4    Yun, S.5    Sun, H.N.6
  • 41
    • 84861664376 scopus 로고    scopus 로고
    • The cytosolic protein G0S2 maintains quiescence in hematopoietic stem cells
    • PMID:22693613
    • Yamada T, Park CS, Burns A, Nakada D, Lacorazza HD. The cytosolic protein G0S2 maintains quiescence in hematopoietic stem cells. PLoS One 2012; 7:e38280; PMID:22693613; http://dx.doi.org/10.1371/journal.pone.0038280
    • (2012) PLoS One , vol.7
    • Yamada, T.1    Park, C.S.2    Burns, A.3    Nakada, D.4    Lacorazza, H.D.5
  • 42
    • 0026094018 scopus 로고
    • A human putative lymphocyte G0/G1 switch gene containing a CpG-rich island encodes a small basic protein with the potential to be phosphorylated
    • PMID:1930693
    • Russell L, Forsdyke DR. A human putative lymphocyte G0/G1 switch gene containing a CpG-rich island encodes a small basic protein with the potential to be phosphorylated. DNA Cell Biol 1991; 10:581-91; PMID:1930693; http://dx.doi.org/10.1089/dna.1991.10.581
    • (1991) DNA Cell Biol , vol.10 , pp. 581-591
    • Russell, L.1    Forsdyke, D.R.2
  • 43
    • 0031419262 scopus 로고    scopus 로고
    • Cyclosporin A inhibits early mRNA expression of G0/G1 switch gene 2 (G0S2) in cultured human blood mononuclear cells
    • PMID:9428793
    • Cristillo AD, Heximer SP, Russell L, Forsdyke DR. Cyclosporin A inhibits early mRNA expression of G0/G1 switch gene 2 (G0S2) in cultured human blood mononuclear cells. DNA Cell Biol 1997; 16:1449-58; PMID:9428793; http://dx.doi.org/10.1089/dna.1997.16.1449
    • (1997) DNA Cell Biol , vol.16 , pp. 1449-1458
    • Cristillo, A.D.1    Heximer, S.P.2    Russell, L.3    Forsdyke, D.R.4
  • 44
    • 29144451332 scopus 로고    scopus 로고
    • The G0/G1 switch gene 2 is a novel PPAR target gene
    • PMID:16086669
    • Zandbergen F, Mandard S, Escher P, Tan NS, Patsouris D, Jatkoe T, et al. The G0/G1 switch gene 2 is a novel PPAR target gene. Biochem J 2005; 392:313-24; PMID:16086669; http://dx.doi.org/10.1042/BJ20050636
    • (2005) Biochem J , vol.392 , pp. 313-324
    • Zandbergen, F.1    Mandard, S.2    Escher, P.3    Tan, N.S.4    Patsouris, D.5    Jatkoe, T.6
  • 45
    • 34447550270 scopus 로고    scopus 로고
    • Activation of PPARdelta inhibits cardiac fibroblast proliferation and the transdifferentiation into myofibroblasts
    • PMID:17543901
    • Teunissen BE, Smeets PJ, Willemsen PH, De Windt LJ, Van der Vusse GJ, Van Bilsen M. Activation of PPARdelta inhibits cardiac fibroblast proliferation and the transdifferentiation into myofibroblasts. Cardiovasc Res 2007; 75:519-29; PMID:17543901; http://dx.doi.org/10.1016/j.cardiores.2007.04.026
    • (2007) Cardiovasc Res , vol.75 , pp. 519-529
    • Teunissen, B.E.1    Smeets, P.J.2    Willemsen, P.H.3    De Windt, L.J.4    Van Der Vusse, G.J.5    Van Bilsen, M.6
  • 46
    • 77249118270 scopus 로고    scopus 로고
    • The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase
    • PMID:20197052
    • Yang X, Lu X, Lombès M, Rha GB, Chi YI, Guerin TM, et al. The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase. Cell Metab 2010; 11:194-205; PMID:20197052; http://dx.doi.org/10.1016/j. cmet.2010.02.003
    • (2010) Cell Metab , vol.11 , pp. 194-205
    • Yang, X.1    Lu, X.2    Lombès, M.3    Rha, G.B.4    Chi, Y.I.5    Guerin, T.M.6
  • 47
    • 4344628907 scopus 로고    scopus 로고
    • Inverse correlation between cyclin A1 hypermethylation and p53 mutation in head and neck cancer identified by reversal of epigenetic silencing
    • PMID:15342377
    • Tokumaru Y, Yamashita K, Osada M, Nomoto S, Sun DI, Xiao Y, et al. Inverse correlation between cyclin A1 hypermethylation and p53 mutation in head and neck cancer identified by reversal of epigenetic silencing. Cancer Res 2004; 64:5982-7; PMID:15342377; http://dx.doi.org/10.1158/0008-5472.CAN-04-0993
    • (2004) Cancer Res , vol.64 , pp. 5982-5987
    • Tokumaru, Y.1    Yamashita, K.2    Osada, M.3    Nomoto, S.4    Sun, D.I.5    Xiao, Y.6
  • 48
    • 70450253169 scopus 로고    scopus 로고
    • Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists
    • PMID:19878646
    • Kusakabe M, Watanabe K, Emoto N, Aki N, Kage H, Nagase T, et al. Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists. Biochem Biophys Res Commun 2009; 390:1283-7; PMID:19878646; http://dx.doi.org/10.1016/j. bbrc.2009.10.137
    • (2009) Biochem Biophys Res Commun , vol.390 , pp. 1283-1287
    • Kusakabe, M.1    Watanabe, K.2    Emoto, N.3    Aki, N.4    Kage, H.5    Nagase, T.6
  • 49
    • 0038495988 scopus 로고    scopus 로고
    • Expression profiling of endometrium from women with endometriosis reveals candidate genes for disease-based implantation failure and infertility
    • PMID:12810542
    • Kao LC, Germeyer A, Tulac S, Lobo S, Yang JP, Taylor RN, et al. Expression profiling of endometrium from women with endometriosis reveals candidate genes for disease-based implantation failure and infertility. Endocrinology 2003; 144:2870-81; PMID:12810542; http://dx.doi.org/10.1210/en. 2003-0043
    • (2003) Endocrinology , vol.144 , pp. 2870-2881
    • Kao, L.C.1    Germeyer, A.2    Tulac, S.3    Lobo, S.4    Yang, J.P.5    Taylor, R.N.6
  • 50
    • 0041565060 scopus 로고    scopus 로고
    • Microarray analysis uncovers retinoid targets in human bronchial epithelial cells
    • PMID:12894236
    • Ma Y, Koza-Taylor PH, DiMattia DA, Hames L, Fu H, Dragnev KH, et al. Microarray analysis uncovers retinoid targets in human bronchial epithelial cells. Oncogene 2003; 22:4924-32; PMID:12894236; http://dx.doi.org/10.1038/sj. onc.1206728
    • (2003) Oncogene , vol.22 , pp. 4924-4932
    • Ma, Y.1    Koza-Taylor, P.H.2    Dimattia, D.A.3    Hames, L.4    Fu, H.5    Dragnev, K.H.6
  • 51
    • 33750912016 scopus 로고    scopus 로고
    • Isolation and expression profiling of genes upregulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients
    • PMID:17082220
    • Nakamura N, Shimaoka Y, Tougan T, Onda H, Okuzaki D, Zhao H, et al. Isolation and expression profiling of genes upregulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients. DNA Res 2006; 13:169-83; PMID:17082220; http://dx.doi.org/10.1093/dnares/dsl006
    • (2006) DNA Res , vol.13 , pp. 169-183
    • Nakamura, N.1    Shimaoka, Y.2    Tougan, T.3    Onda, H.4    Okuzaki, D.5    Zhao, H.6
  • 52
    • 56149110408 scopus 로고    scopus 로고
    • Expression profiling of PBMC-based diagnostic gene markers isolated from vasculitis patients
    • PMID:18562305
    • Kobayashi S, Ito A, Okuzaki D, Onda H, Yabuta N, Nagamori I, et al. Expression profiling of PBMC-based diagnostic gene markers isolated from vasculitis patients. DNA Res 2008; 15:253-65; PMID:18562305; http://dx.doi.org/10.1093/dnares/dsn014
    • (2008) DNA Res , vol.15 , pp. 253-265
    • Kobayashi, S.1    Ito, A.2    Okuzaki, D.3    Onda, H.4    Yabuta, N.5    Nagamori, I.6
  • 53
    • 22544480310 scopus 로고    scopus 로고
    • Gene expression profiling of peripheral blood mononuclear leukocytes from psoriasis patients identifies new immune regulatory molecules
    • PMID:16048752
    • Koczan D, Guthke R, Thiesen HJ, Ibrahim SM, Kundt G, Krentz H, et al. Gene expression profiling of peripheral blood mononuclear leukocytes from psoriasis patients identifies new immune regulatory molecules. Eur J Dermatol 2005; 15:251-7; PMID:16048752
    • (2005) Eur J Dermatol , vol.15 , pp. 251-257
    • Koczan, D.1    Guthke, R.2    Thiesen, H.J.3    Ibrahim, S.M.4    Kundt, G.5    Krentz, H.6
  • 54
    • 5444253109 scopus 로고    scopus 로고
    • Exploration of replicative senescence-associated genes in human dermal fibroblasts by cDNA microarray technology
    • PMID:15489060
    • Yoon IK, Kim HK, Kim YK, Song IH, Kim W, Kim S, et al. Exploration of replicative senescence-associated genes in human dermal fibroblasts by cDNA microarray technology. Exp Gerontol 2004; 39:1369-78; PMID:15489060; http://dx.doi.org/10.1016/j. exger.2004.07.002
    • (2004) Exp Gerontol , vol.39 , pp. 1369-1378
    • Yoon, I.K.1    Kim, H.K.2    Kim, Y.K.3    Song, I.H.4    Kim, W.5    Kim, S.6
  • 55
    • 34249777555 scopus 로고    scopus 로고
    • Functions of the histone chaperone nucleolin in diseases
    • PMID:17484127
    • Storck S, Shukla M, Dimitrov S, Bouvet P. Functions of the histone chaperone nucleolin in diseases. Subcell Biochem 2007; 41:125-44; PMID:17484127; http://dx.doi.org/10.1007/1-4020-5466-1-7
    • (2007) Subcell Biochem , vol.41 , pp. 125-144
    • Storck, S.1    Shukla, M.2    Dimitrov, S.3    Bouvet, P.4
  • 56
    • 33846681638 scopus 로고    scopus 로고
    • Nucleolin: A multiFACeTed protein
    • PMID:17157503
    • Mongelard F, Bouvet P. Nucleolin: a multiFACeTed protein. Trends Cell Biol 2007; 17:80-6; PMID:17157503; http://dx.doi.org/10.1016/j. tcb.2006.11.010
    • (2007) Trends Cell Biol , vol.17 , pp. 80-86
    • Mongelard, F.1    Bouvet, P.2
  • 57
    • 26844578691 scopus 로고    scopus 로고
    • Role of nucleolin in posttranscriptional control of MMP-9 expression
    • PMID:16153722
    • Fähling M, Steege A, Perlewitz A, Nafz B, Mrowka R, Persson PB, et al. Role of nucleolin in posttranscriptional control of MMP-9 expression. Biochim Biophys Acta 2005; 1731:32-40; PMID:16153722; http://dx.doi.org/10.1016/ j.bbaexp.2005.08.005
    • (2005) Biochim Biophys Acta , vol.1731 , pp. 32-40
    • Fähling, M.1    Steege, A.2    Perlewitz, A.3    Nafz, B.4    Mrowka, R.5    Persson, P.B.6
  • 58
    • 33947609348 scopus 로고    scopus 로고
    • Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA
    • PMID:17179226
    • Otake Y, Soundararajan S, Sengupta TK, Kio EA, Smith JC, Pineda-Roman M, et al. Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA. Blood 2007; 109:3069-75; PMID:17179226
    • (2007) Blood , vol.109 , pp. 3069-3075
    • Otake, Y.1    Soundararajan, S.2    Sengupta, T.K.3    Kio, E.A.4    Smith, J.C.5    Pineda-Roman, M.6
  • 59
    • 80455168361 scopus 로고    scopus 로고
    • Enhanced translation by Nucleolin via G-rich elements in coding and non-coding regions of target mRNAs
    • PMID:21737422
    • Abdelmohsen K, Tominaga K, Lee EK, Srikantan S, Kang MJ, Kim MM, et al. Enhanced translation by Nucleolin via G-rich elements in coding and non-coding regions of target mRNAs. Nucleic Acids Res 2011; 39:8513-30; PMID:21737422; http://dx.doi.org/10.1093/nar/gkr488
    • (2011) Nucleic Acids Res , vol.39 , pp. 8513-8530
    • Abdelmohsen, K.1    Tominaga, K.2    Lee, E.K.3    Srikantan, S.4    Kang, M.J.5    Kim, M.M.6
  • 60
    • 70149097778 scopus 로고    scopus 로고
    • Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2
    • PMID:19706769
    • Welch C, Santra MK, El-Assaad W, Zhu X, Huber WE, Keys RA, et al. Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2. Cancer Res 2009; 69:6782-9; PMID:19706769; http://dx.doi.org/10.1158/0008-5472.CAN-09-0128
    • (2009) Cancer Res , vol.69 , pp. 6782-6789
    • Welch, C.1    Santra, M.K.2    El-Assaad, W.3    Zhu, X.4    Huber, W.E.5    Keys, R.A.6
  • 61
    • 3242669145 scopus 로고    scopus 로고
    • Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche
    • PMID:15260986
    • Arai F, Hirao A, Ohmura M, Sato H, Matsuoka S, Takubo K, et al. Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell 2004; 118:149-61; PMID:15260986; http://dx.doi.org/10.1016/j. cell.2004.07.004
    • (2004) Cell , vol.118 , pp. 149-161
    • Arai, F.1    Hirao, A.2    Ohmura, M.3    Sato, H.4    Matsuoka, S.5    Takubo, K.6
  • 62
    • 36748999351 scopus 로고    scopus 로고
    • Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche
    • PMID:18371409
    • Yoshihara H, Arai F, Hosokawa K, Hagiwara T, Takubo K, Nakamura Y, et al. Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche. Cell Stem Cell 2007; 1:685-97; PMID:18371409; http://dx.doi.org/10.1016/j.stem.2007.10.020
    • (2007) Cell Stem Cell , vol.1 , pp. 685-697
    • Yoshihara, H.1    Arai, F.2    Hosokawa, K.3    Hagiwara, T.4    Takubo, K.5    Nakamura, Y.6
  • 63
    • 39749178390 scopus 로고    scopus 로고
    • Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo
    • PMID:18371452
    • Fleming HE, Janzen V, Lo Celso C, Guo J, Leahy KM, Kronenberg HM, et al. Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell Stem Cell 2008; 2:274-83; PMID:18371452; http://dx.doi.org/10.1016/j.stem.2008.01.003
    • (2008) Cell Stem Cell , vol.2 , pp. 274-283
    • Fleming, H.E.1    Janzen, V.2    Lo Celso, C.3    Guo, J.4    Leahy, K.M.5    Kronenberg, H.M.6
  • 64
    • 33748850636 scopus 로고    scopus 로고
    • Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block
    • PMID:16951689
    • Kirstetter P, Anderson K, Porse BT, Jacobsen SE, Nerlov C. Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nat Immunol 2006; 7:1048-56; PMID:16951689; http://dx.doi.org/10.1038/ni1381
    • (2006) Nat Immunol , vol.7 , pp. 1048-1056
    • Kirstetter, P.1    Anderson, K.2    Porse, B.T.3    Jacobsen, S.E.4    Nerlov, C.5
  • 65
    • 0142245613 scopus 로고    scopus 로고
    • TGF-beta signaling-deficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro
    • PMID:12842983
    • Larsson J, Blank U, Helgadottir H, Björnsson JM, Ehinger M, Goumans MJ, et al. TGF-beta signaling-deficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro. Blood 2003; 102:3129-35; PMID:12842983; http://dx.doi.org/10. 1182/blood-2003-04-1300
    • (2003) Blood , vol.102 , pp. 3129-3135
    • Larsson, J.1    Blank, U.2    Helgadottir, H.3    Björnsson, J.M.4    Ehinger, M.5    Goumans, M.J.6
  • 66
    • 42249103574 scopus 로고    scopus 로고
    • CXCR4 is required for the quiescence of primitive hematopoietic cells
    • PMID:18378795
    • Nie Y, Han YC, Zou YR. CXCR4 is required for the quiescence of primitive hematopoietic cells. J Exp Med 2008; 205:777-83; PMID:18378795; http://dx.doi.org/10.1084/jem.20072513
    • (2008) J Exp Med , vol.205 , pp. 777-783
    • Nie, Y.1    Han, Y.C.2    Zou, Y.R.3
  • 67
    • 21244472780 scopus 로고    scopus 로고
    • Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size
    • PMID:15928197
    • Stier S, Ko Y, Forkert R, Lutz C, Neuhaus T, Grünewald E, et al. Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size. J Exp Med 2005; 201:1781-91; PMID:15928197; http://dx.doi.org/10.1084/jem.20041992
    • (2005) J Exp Med , vol.201 , pp. 1781-1791
    • Stier, S.1    Ko, Y.2    Forkert, R.3    Lutz, C.4    Neuhaus, T.5    Grünewald, E.6
  • 68
    • 21344474104 scopus 로고    scopus 로고
    • Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells
    • PMID:15845900
    • Nilsson SK, Johnston HM, Whitty GA, Williams B, Webb RJ, Denhardt DT, et al. Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells. Blood 2005; 106:1232-9; PMID:15845900; http://dx.doi.org/10.1182/blood-2004-11-4422
    • (2005) Blood , vol.106 , pp. 1232-1239
    • Nilsson, S.K.1    Johnston, H.M.2    Whitty, G.A.3    Williams, B.4    Webb, R.J.5    Denhardt, D.T.6
  • 69
    • 77950624255 scopus 로고    scopus 로고
    • Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors
    • PMID:20107231
    • Merchant A, Joseph G, Wang Q, Brennan S, Matsui W. Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors. Blood 2010; 115:2391-6; PMID:20107231; http://dx.doi.org/10.1182/blood-2009-09-241703
    • (2010) Blood , vol.115 , pp. 2391-2396
    • Merchant, A.1    Joseph, G.2    Wang, Q.3    Brennan, S.4    Matsui, W.5
  • 70
    • 0344235135 scopus 로고    scopus 로고
    • Membranebound stem cell factor is a key regulator in the initial lodgment of stem cells within the endosteal marrow region
    • PMID:14662336
    • Driessen RL, Johnston HM, Nilsson SK. Membranebound stem cell factor is a key regulator in the initial lodgment of stem cells within the endosteal marrow region. Exp Hematol 2003; 31:1284-91; PMID:14662336; http://dx.doi.org/10.1016/ j. exphem.2003.08.015
    • (2003) Exp Hematol , vol.31 , pp. 1284-1291
    • Driessen, R.L.1    Johnston, H.M.2    Nilsson, S.K.3
  • 71
    • 52949114971 scopus 로고    scopus 로고
    • Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family
    • PMID:18940733
    • Viatour P, Somervaille TC, Venkatasubrahmanyam S, Kogan S, McLaughlin ME, Weissman IL, et al. Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family. Cell Stem Cell 2008; 3:416-28; PMID:18940733; http://dx.doi.org/10.1016/j. stem.2008.07.009
    • (2008) Cell Stem Cell , vol.3 , pp. 416-428
    • Viatour, P.1    Somervaille, T.C.2    Venkatasubrahmanyam, S.3    Kogan, S.4    McLaughlin, M.E.5    Weissman, I.L.6
  • 72
    • 4444307411 scopus 로고    scopus 로고
    • Mouse development and cell proliferation in the absence of D-cyclins
    • PMID:15315760
    • Kozar K, Ciemerych MA, Rebel VI, Shigematsu H, Zagozdzon A, Sicinska E, et al. Mouse development and cell proliferation in the absence of D-cyclins. Cell 2004; 118:477-91; PMID:15315760; http://dx.doi. org/10.1016/j.cell.2004.07. 025
    • (2004) Cell , vol.118 , pp. 477-491
    • Kozar, K.1    Ciemerych, M.A.2    Rebel, V.I.3    Shigematsu, H.4    Zagozdzon, A.5    Sicinska, E.6
  • 73
    • 4444247138 scopus 로고    scopus 로고
    • Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6
    • PMID:15315761
    • Malumbres M, Sotillo R, Santamaría D, Galán J, Cerezo A, Ortega S, et al. Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6. Cell 2004; 118:493-504; PMID:15315761; http://dx.doi.org/10.1016/j.cell.2004.08.002
    • (2004) Cell , vol.118 , pp. 493-504
    • Malumbres, M.1    Sotillo, R.2    Santamaría, D.3    Galán, J.4    Cerezo, A.5    Ortega, S.6
  • 74
    • 77949322674 scopus 로고    scopus 로고
    • Scl regulates the quiescence and the long-term competence of hematopoietic stem cells
    • PMID:19850742
    • Lacombe J, Herblot S, Rojas-Sutterlin S, Haman A, Barakat S, Iscove NN, et al. Scl regulates the quiescence and the long-term competence of hematopoietic stem cells. Blood 2010; 115:792-803; PMID:19850742; http://dx.doi.org/10.1182/blood-2009-01-201384
    • (2010) Blood , vol.115 , pp. 792-803
    • Lacombe, J.1    Herblot, S.2    Rojas-Sutterlin, S.3    Haman, A.4    Barakat, S.5    Iscove, N.N.6
  • 75
    • 80053452629 scopus 로고    scopus 로고
    • The ups and downs of p53 regulation in hematopoietic stem cells
    • PMID:21957490
    • Abbas HA, Pant V, Lozano G. The ups and downs of p53 regulation in hematopoietic stem cells. Cell Cycle 2011; 10:3257-62; PMID:21957490; http://dx.doi. org/10.4161/cc.10.19.17721
    • (2011) Cell Cycle , vol.10 , pp. 3257-3262
    • Abbas, H.A.1    Pant, V.2    Lozano, G.3
  • 76
    • 84865414435 scopus 로고    scopus 로고
    • Necdin, a p53 target gene, regulates the quiescence and response to genotoxic stress of hematopoietic stem/progenitor cells
    • PMID:22776820
    • Asai T, Liu Y, Di Giandomenico S, Bae N, Ndiaye-Lobry D, Deblasio A, et al. Necdin, a p53 target gene, regulates the quiescence and response to genotoxic stress of hematopoietic stem/progenitor cells. Blood 2012; 120:1601-12; PMID:22776820; http://dx.doi. org/10.1182/blood-2011-11-393983
    • (2012) Blood , vol.120 , pp. 1601-1612
    • Asai, T.1    Liu, Y.2    Di Giandomenico, S.3    Bae, N.4    Ndiaye-Lobry, D.5    Deblasio, A.6
  • 77
    • 79952176472 scopus 로고    scopus 로고
    • Ex vivo maintenance of hematopoietic stem cells by quiescence induction through Fbxw7α overexpression
    • PMID:21190997
    • Iriuchishima H, Takubo K, Matsuoka S, Onoyama I, Nakayama KI, Nojima Y, et al. Ex vivo maintenance of hematopoietic stem cells by quiescence induction through Fbxw7α overexpression. Blood 2011; 117:2373-7; PMID:21190997; http://dx.doi.org/10.1182/blood-2010-07-294801
    • (2011) Blood , vol.117 , pp. 2373-2377
    • Iriuchishima, H.1    Takubo, K.2    Matsuoka, S.3    Onoyama, I.4    Nakayama, K.I.5    Nojima, Y.6
  • 78
    • 84860528235 scopus 로고    scopus 로고
    • The ATM-BID pathway regulates quiescence and survival of haematopoietic stem cells
    • PMID:22446738
    • Maryanovich M, Oberkovitz G, Niv H, Vorobiyov L, Zaltsman Y, Brenner O, et al. The ATM-BID pathway regulates quiescence and survival of haematopoietic stem cells. Nat Cell Biol 2012; 14:535-41; PMID:22446738; http://dx.doi.org/10. 1038/ncb2468
    • (2012) Nat Cell Biol , vol.14 , pp. 535-541
    • Maryanovich, M.1    Oberkovitz, G.2    Niv, H.3    Vorobiyov, L.4    Zaltsman, Y.5    Brenner, O.6
  • 79
    • 43249083123 scopus 로고    scopus 로고
    • The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation
    • PMID:18451107
    • Yoshida T, Hazan I, Zhang J, Ng SY, Naito T, Snippert HJ, et al. The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation. Genes Dev 2008; 22:1174-89; PMID:18451107; http://dx.doi.org/10.1101/gad.1642808
    • (2008) Genes Dev , vol.22 , pp. 1174-1189
    • Yoshida, T.1    Hazan, I.2    Zhang, J.3    Ng, S.Y.4    Naito, T.5    Snippert, H.J.6
  • 80
    • 80054834594 scopus 로고    scopus 로고
    • The Paf oncogene is essential for hematopoietic stem cell function and development
    • PMID:21844206
    • Amrani YM, Gill J, Matevossian A, Alonzo ES, Yang C, Shieh JH, et al. The Paf oncogene is essential for hematopoietic stem cell function and development. J Exp Med 2011; 208:1757-65; PMID:21844206; http://dx.doi.org/10.1084/jem. 20102170
    • (2011) J Exp Med , vol.208 , pp. 1757-1765
    • Amrani, Y.M.1    Gill, J.2    Matevossian, A.3    Alonzo, E.S.4    Yang, C.5    Shieh, J.H.6
  • 81
    • 84861486777 scopus 로고    scopus 로고
    • Hematopoietic stem cells lacking Ott1 display aspects associated with aging and are unable to maintain quiescence during proliferative stress
    • PMID:22490678
    • Xiao N, Jani K, Morgan K, Okabe R, Cullen DE, Jesneck JL, et al. Hematopoietic stem cells lacking Ott1 display aspects associated with aging and are unable to maintain quiescence during proliferative stress. Blood 2012; 119:4898-907; PMID:22490678; http://dx.doi.org/10.1182/blood-2012-01-403089
    • (2012) Blood , vol.119 , pp. 4898-4907
    • Xiao, N.1    Jani, K.2    Morgan, K.3    Okabe, R.4    Cullen, D.E.5    Jesneck, J.L.6
  • 82
    • 48749084130 scopus 로고    scopus 로고
    • Lnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2
    • PMID:18618018
    • Bersenev A, Wu C, Balcerek J, Tong W. Lnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2. J Clin Invest 2008; 118:2832-44; PMID:18618018
    • (2008) J Clin Invest , vol.118 , pp. 2832-2844
    • Bersenev, A.1    Wu, C.2    Balcerek, J.3    Tong, W.4
  • 83
    • 84855568843 scopus 로고    scopus 로고
    • Homeostasis of hematopoietic stem cells regulated by the myeloproliferative disease associated-gene product Lnk/Sh2b3 via Bcl-xL
    • e3; PMID:22101255
    • Suzuki N, Yamazaki S, Ema H, Yamaguchi T, Nakauchi H, Takaki S. Homeostasis of hematopoietic stem cells regulated by the myeloproliferative disease associated-gene product Lnk/Sh2b3 via Bcl-xL. Exp Hematol 2012; 40:166-74, e3; PMID:22101255; http://dx.doi.org/10.1016/j.exphem.2011.11.003
    • (2012) Exp Hematol , vol.40 , pp. 166-174
    • Suzuki, N.1    Yamazaki, S.2    Ema, H.3    Yamaguchi, T.4    Nakauchi, H.5    Takaki, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.