Activation of PPARδ inhibits cardiac fibroblast proliferation and the transdifferentiation into myofibroblasts

Cardiovascular Research

Volumn 75, Issue 3, 2007, Pages 519-529

  Teunissen, Birgit E J ^a   Smeets, Pascal J H ^a   Willemsen, Peter H M ^a   De Windt, Leon J ^b   Van der Vusse, Ger J ^a   Van Bilsen, Marc ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

Author keywords

Cardiac fibroblast; Cardiac myofibroblast; Collagen; Peroxisome Proliferator Activated Receptor (PPAR); PPAR ; Proliferation; Transdifferentiation

Indexed keywords

[2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; ALPHA SMOOTH MUSCLE ACTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIRINIXIC ACID; PROLINE; ROSIGLITAZONE; UNCOUPLING PROTEIN 2; 2,4 THIAZOLIDINEDIONE DERIVATIVE; COLLAGEN; LIGAND; PEROXISOME PROLIFERATOR; PYRIMIDINE DERIVATIVE; THIAZOLE DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; FIBROBLAST; GENE ACTIVITY; GENE EXPRESSION; GENE OVEREXPRESSION; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; MYOFIBROBLAST; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; DRUG EFFECT; FIBROSIS; GENETIC TRANSDUCTION; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; LEWIS RAT; METABOLISM; METHODOLOGY;

ANIMALS; ANIMALS, NEWBORN; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN; FIBROBLASTS; FIBROSIS; HUMANS; IMMUNOHISTOCHEMISTRY; LIGANDS; MYOCYTES, CARDIAC; PEROXISOME PROLIFERATORS; PPAR ALPHA; PPAR DELTA; PPAR GAMMA; PYRIMIDINES; RATS; RATS, INBRED LEW; THIAZOLES; THIAZOLIDINEDIONES; TRANSDUCTION, GENETIC;

EID: 34447550270     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2007.04.026     Document Type: Article

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