DXR inhibition by potent mono- and disubstituted fosmidomycin analogues

Journal of Medicinal Chemistry

Volumn 56, Issue 15, 2013, Pages 6190-6199

  Jansson, Anna M ^a   Wieì̈ckowska, Anna ^a   Björkelid, Christofer ^a   Yahiaoui, Samir ^a   Sooriyaarachchi, Sanjeewani ^a   Lindh, Martin ^a   Bergfors, Terese ^a   Dharavath, Shyamraj ^a   Desroses, Matthieu ^a   Suresh, Surisetti ^a   Andaloussi, Mounir ^a   Nikhil, Rautela ^b   Sreevalli, Sharma ^b   Srinivasa, Bachally R ^b   Larhed, Mats ^a   Jones, T Alwyn ^a   Karlén, Anders ^a   Mowbray, Sherry L ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; FOSMIDOMYCIN; FOSMIDOMYCIN DERIVATIVE; HYDROXAMIC ACID; UNCLASSIFIED DRUG;

APICOMPLEXA; ARTICLE; BINDING SITE; IC 50; IN VITRO STUDY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PLASMODIUM FALCIPARUM;

ALDOSE-KETOSE ISOMERASES; ANTIMALARIALS; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; FOSFOMYCIN; HYDROXAMIC ACIDS; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84881466635     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm4006498     Document Type: Article

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