Synthesis and evaluation of α-halogenated analogues of 3-(acetylhydroxyamino)propylphosphonic acid (FR900098) as antimalarials

Journal of Medicinal Chemistry

Volumn 53, Issue 14, 2010, Pages 5342-5346

  Verbrugghen, Thomas ^a   Cos, Paul ^b   Maes, Louis ^b   Van Calenbergh, Serge ^a  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

3 (ACETYLHYDROXYAMINO)PROPYLPHOSPHONIC ACID; 3 (N HYDROXY N METHYLCARBAMOYL) 1 FLUOROPROPYLPHOSPHONIC ACID; 3 (N HYDROXYACETAMIDO) 1 FLUOROPROPYLPHOSPHONIC ACID; CHLOROQUINE; FOSMIDOMYCIN; PHOSPHONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; HALOGENATION; MOUSE; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM;

ACUTE DISEASE; ANIMALS; ANTIMALARIALS; FOSFOMYCIN; MALARIA; MICE; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77954734834     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm100211e     Document Type: Article

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