Homologous 2?,5?-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 32, 2013, Pages 13114-13119

  Zhang, Rong ^a,b   Jha, Babal K ^c   Ogden, Kristen M ^d   Dong, Beihua ^c   Zhao, Ling ^a   Elliott, Ruth ^a   Patton, John T ^d   Silverman, Robert H ^c   Weiss, Susan R ^a,e  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b INSTITUTE OF PLANT PROTECTION   (China)

^c LERNER RESEARCH INSTITUTE   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^e HUAZHONG AGRICULTURAL UNIVERSITY   (China)

Author keywords

Interferon stiumulated gene; Nidovirales; Reoviridae; RNA capping enzyme

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE; 2',5' PHOSPHODIESTERASE DERIVATIVE; CORE PROTEIN; PHOSPHODIESTERASE; RIBONUCLEASE L; RIBOSOME RNA; UNCLASSIFIED DRUG; VIRUS ENZYME;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHIMERA; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; INNATE IMMUNITY; MACROPHAGE; MOUSE; MURINE HEPATITIS CORONAVIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; RNA DEGRADATION; ROTAVIRUS; STRUCTURAL HOMOLOGY; VIRUS MUTANT; VIRUS REPLICATION;

INTERFERON-STIUMULATED GENE; NIDOVIRALES; REOVIRIDAE; RNA CAPPING ENZYME;

2',5'-OLIGOADENYLATE SYNTHETASE; ADENINE NUCLEOTIDES; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CAPSID PROTEINS; CELL LINE; CELLS, CULTURED; ENDORIBONUCLEASES; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; IMMUNOBLOTTING; MACROPHAGES; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; MURINE HEPATITIS VIRUS; MUTATION; OLIGORIBONUCLEOTIDES; PHOSPHORIC DIESTER HYDROLASES; RNA VIRUS INFECTIONS; RNA VIRUSES; ROTAVIRUS; SEQUENCE HOMOLOGY, AMINO ACID; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84881415860     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1306917110     Document Type: Article

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