Murine coronavirus evolution in vivo: Functional compensation of a detrimental amino acid substitution in the receptor binding domain of the spike glycoprotein

Journal of Virology

Volumn 79, Issue 12, 2005, Pages 7629-7640

  Navas Martin, Sonia ^a,b   Hingley, Susan T ^a,c   Weiss, Susan R ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c PHILADELPHIA COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARTIC ACID; GLUTAMIC ACID; GLUTAMINE; HISTIDINE; LEUCINE; VIRUS GLYCOPROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONAVIRUS; EVOLUTION; GLIA CELL; HEPATITIS; LIVER; MALE; MOUSE; NONHUMAN; PERSISTENT VIRUS INFECTION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR BINDING; REVERTANT; RNA RECOMBINATION; SPIKE GENE; VIRUS GENE; VIRUS ISOLATION; VIRUS MUTANT; VIRUS REPLICATION; VIRUS VIRULENCE;

AMINO ACID SUBSTITUTION; ANIMALS; CORONAVIRUS INFECTIONS; EVOLUTION, MOLECULAR; HEPATITIS, VIRAL, ANIMAL; LIVER; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MURINE HEPATITIS VIRUS; RECEPTORS, VIRUS; RECOMBINATION, GENETIC; SPECIFIC PATHOGEN-FREE ORGANISMS; VIRAL ENVELOPE PROTEINS; VIRULENCE;

CORONAVIRUS; MURINAE; MURINE HEPATITIS VIRUS;

EID: 19944382171     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.12.7629-7640.2005     Document Type: Article

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