RANKL-induced DC-STAMP is essential for osteoclastogenesis

Journal of Experimental Medicine

Volumn 200, Issue 7, 2004, Pages 941-946

  Kukita, Toshio ^a   Wada, Naohisa ^a   Kukita, Akiko ^b   Kakimoto, Takashi ^b   Sandra, Ferry ^a   Toh, Kazuko ^a   Nagata, Kengo ^a   Iijima, Tadahiko ^a   Horiuchi, Madoka ^c,d   Matsusaki, Hiromi ^d   Hieshima, Kunio ^e   Yoshie, Osamu ^e   Nomiyama, Hisayuki ^c  

^a KYUSHU UNIVERSITY   (Japan)

^b SAGA UNIVERSITY   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

^d PREFECTURAL UNIVERSITY OF KUMAMOTO   (Japan)

^e KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Adhesion; Cell fusion; Osteoclast; Seven transmembrane receptor; TRAP

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CYTOKINE; DENDRITIC CELL SPECIFIC TRANSMEMBRANE PROTEIN; MEMBRANE PROTEIN; OSTEOCLAST DIFFERENTIATION FACTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE REMODELING; CELL FUSION; CELL MATURATION; CELL STIMULATION; CONTROLLED STUDY; DENDRITIC CELL; GENE ACTIVATION; GENE OVEREXPRESSION; GIANT CELL; MONONUCLEAR CELL; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; STEM CELL;

ACID PHOSPHATASE; ANIMALS; BLOTTING, NORTHERN; CARRIER PROTEINS; CELLS, CULTURED; DENDRITIC CELLS; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; OLIGONUCLEOTIDES; OSTEOCLASTS; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 5444229284     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20040518     Document Type: Article

References (23)

1. Roodman, G.D. 1999. Cell biology of the osteoclast. Exp. Hematol. 27:1229-1241.
2. Suda, T., N. Takahashi, N. Udagawa, E. Jimi, M.T. Gillespie, and T.J. Martin. 1999. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr. Rev. 20:345-357.
3. Boyle, W.J., W.S. Simonet, and D.L. Lacey. 2003. Osteoclast differentiation and activation. Nature. 423:337-342.
4. Teitelbaum, S.L., and F.P. Ross. 2003. Genetic regulation of osteoclast development and function. Nat. Rev. Genet. 4:638-649.
5. Han, X., H. Sterling, Y. Chen, C. Saginario, E.J. Brown, W.A. Frazier, F.P. Lindberg, and A. Vignery. 2000. CD47, a ligand for the macrophage fusion receptor, participates in macrophage multinucleation. J. Biol. Chem. 275:37984-37992.
6. Vignery, A. 2000. Osteoclasts and giant cells: macrophage-macrophage fusion mechanism. Int. J. Exp. Pathol. 81:291-304.
7. Higuchi, S., N. Tabata, M. Tajima, M. Ito, M. Tsurudome, A. Sudo, A. Uchida, and Y. Ito. 1998. Induction of human osteodast-like cells by treatment of blood monocytes with anti-fusion regulatory protein-1/CD98 monoclonal antibodies. J. Bone Miner. Res. 13:44-49.
8. Mbalaviele, G., H. Chen, B.F. Boyce, G.R. Mundy, and T. Yoneda. 1995. The role of cadherin in the generation of multinucleated osteoclasts from mononuclear precursors in murine marrow. J. Clin. Invest. 95:2757-2765.
9. Watanabe, T., T. Kukita, A. Kukita, N. Wada, K. Toh, K., Nagata, H. Nomiyama, and T. Iijima. 2004. Direct stimulation of osteoclastogenesis by MIP-1alpha: evidence obtained from studies using RAW264 cell clone highly responsive to RANKL. J. Endocrinol. 180:193-201.
10. Hartgers, F.C., J.L. Vissers, M.W. Looman, C. van Zoelen, C. Huffine, C.G. Figdor, and G.J. Adema. 2000. DC-STAMP, a novel multimembrane-spanning molecule preferentially expressed by dendritic cells. Eur. J. Immunol. 30:3585-3590.
11. Staege, H., A. Brauchlin, G. Schoedon, and A. Schaffner. 2001. Two novel genes FIND and LIND differentially expressed in deactivated and Listeria-infected human macrophages. Immunogenetics. 53:105-113.
12. Takahashi, N., N. Udagawa, S. Tanaka, and T. Suda. 2003. Generating murine osteoclasts from bone marrow. Methods Mol. Med. 80:129-144.
13. Kukita, T., A. Kukita, K. Nagata, H. Maeda, K. Kurisu, T. Watanabe, and T. Iijima. 1994. Novel cell-surface Ag expressed on rat osteoclasts regulating the function of the calcitonin receptor. J. Immunol. 153:5265-5273.
14. Nakayama, T., K. Hieshima, D. Izawa, Y. Tatsumi, A. Kanamaru, and O. Yoshie. 2003. Cutting edge: profile of chemokine receptor expression on human plasma cells accounts for their efficient recruitment to target tissues. J. Immunol. 170:1136-1140.
15. Yoshida, T., D. Izawa, T. Nakayama, K. Nakahara, M. Kakizaki, T. Imai, R. Suzuki, M. Miyasaka, and O. Yoshie. 1999. Molecular cloning of mXCR1, the murine SCM-1/lymphotactin receptor. FEBS Lett. 458:37-40.
16. Kobayashi, K., N. Takahashi, E. Jimi, N. Udagawa, M. Takami, S. Kotake, N. Nakagawa, M. Kinosaki, K. Yamaguchi, N. Shima, et al. 2000. Tumor necrosis factor α stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J. Exp. Med. 191:275-286.
17. Choi, S.J., J.C. Cruz, F. Craig, H. Chung, R.D. Devlin, G.D. Roodman, and M. Alsina. 2000. Macrophage inflammatory protein 1-alpha is a potential osteoclast stimulatory factor in multiple myeloma. Blood. 96:671-675.
18. Kukita, T., H. Nomiyama, Y. Ohmoto, A. Kukita, T. Shuto, T. Hotokebuchi, Y. Sugioka, R. Miura, and T. Iijima. 1997. Macrophage inflammatory protein-1 alpha (LD78) expressed in human bone marrow: its role in regulation of hematopoiesis and osteoclast recruitment. Lab. Invest. 76:399-406.
19. Ibbotson, K.J., G.D. Roodman, L.M. McManus, and G.R. Mundy. 1984. Identification and characterization of osteoclast-like cells and their progenitors in cultures of feline marrow mononuclear cells. J. Cell Biol. 99:471-480.
20. Rho, J., C.R. Altmann, N.D. Socci, L. Merkov, N. Kim, H. So, O. Lee, M. Takami, A.H. Brivanlou, and Y. Choi. 2002. Gene expression profiling of osteoclast differentiation by combined suppression subtractive hybridization (SSH) and cDNA microarray analysis. DNA Cell Biol. 21:541-549.
21. Imai, T., K. Hieshima, C. Haskell, M. Baba, M. Nagira, M. Nishimura, M. Kakizaki, S. Takagi, H. Nomiyama, T.J. Schall, and O. Yoshie. 1997. Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. Cell. 91:521-530.
22. Hartgers, F.C., M.W. Looman, B. van der Woning, G.F. Merkx, C.G. Figdor, and G.J. Adema. 2001. Genomic organization, chromosomal localization, and 5′ upstream region of the human DC-STAMP gene. Immunogenetics. 53:145-149.
23. Hall, R.A., R.T. Premont, and R.J. Lefkowitz. 1999. Hepta-helical receptor signaling: beyond the G protein paradigm. J. Cell Biol. 145:927-932.