1,1-Bis(3′-indolyl)-1-(p-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth

Molecular Cancer Therapeutics

Volumn 7, Issue 12, 2008, Pages 3825-3833

  Inamoto, Teruo ^a   Papineni, Sabitha ^b   Chintharlapalli, Sudhakar ^b   Cho, Sung Dae ^b   Safe, Stephen ^b   Kamat, Ashish M ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 BIS(3' INDOLYL) 1 (4 CHLOROPHENYL)METHANE; CARBENOID; METHANE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEAR RECEPTOR RELATED FACTOR 1; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BLADDER CANCER; CANCER INHIBITION; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LIGAND BINDING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RNA INTERFERENCE; SUBSTITUTION REACTION; TREATMENT OUTCOME;

ANIMALS; BENZHYDRYL COMPOUNDS; CELL LINE, TUMOR; CELL SURVIVAL; DNA-BINDING PROTEINS; HUMANS; INDOLES; LIGANDS; MALE; MICE; MICE, NUDE; MODELS, BIOLOGICAL; NEOPLASM TRANSPLANTATION; RNA INTERFERENCE; TETRAZOLIUM SALTS; THIAZOLES; TRANSCRIPTION FACTORS; URINARY BLADDER NEOPLASMS;

EID: 57749118143     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-08-0730     Document Type: Article

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