-
1
-
-
0023459992
-
Megakaryoblastic leukemia and Down's syndrome: A review
-
Zipursky A, Peeters M, Poon A. Megakaryoblastic leukemia and Down's syndrome: a review. Pediatr Hematol Oncol. 1987;4(3):211-230.
-
(1987)
Pediatr Hematol Oncol
, vol.4
, Issue.3
, pp. 211-230
-
-
Zipursky, A.1
Peeters, M.2
Poon, A.3
-
2
-
-
0026574340
-
Down syndrome and leukemia
-
Robison LL. Down syndrome and leukemia. Leukemia. 1992;6(Suppl. 1):5-7.
-
(1992)
Leukemia
, vol.6
, Issue.SUPPL. 1
, pp. 5-7
-
-
Robison, L.L.1
-
4
-
-
0032941980
-
Transient myeloproliferative disorder (transient leukemia) and hematologic manifestations of Down syndrome
-
vii.
-
Zipursky A, Brown EJ, Christensen H, Doyle J. Transient myeloproliferative disorder (transient leukemia) and hematologic manifestations of Down syndrome. Clin Lab Med. 1999;19(1):157-167, vii.
-
(1999)
Clin Lab Med
, vol.19
, Issue.1
, pp. 157-167
-
-
Zipursky, A.1
Brown, E.J.2
Christensen, H.3
Doyle, J.4
-
5
-
-
18944363334
-
Immunophenotype of Down syndrome acute myeloid leukemia and transient myeloproliferative disease differs significantly from other diseases with morphologically identical or similar blasts
-
Langebrake C, Creutzig U, Reinhardt D. Immunophenotype of Down syndrome acute myeloid leukemia and transient myeloproliferative disease differs significantly from other diseases with morphologically identical or similar blasts. Klin Padiatr. 2005; 217(3):126-134.
-
(2005)
Klin Padiatr
, vol.217
, Issue.3
, pp. 126-134
-
-
Langebrake, C.1
Creutzig, U.2
Reinhardt, D.3
-
6
-
-
33644759290
-
Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling
-
Bourquin JP, et al. Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling. Proc Natl Acad Sci U S A. 2006;103(9):3339-3344.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.9
, pp. 3339-3344
-
-
Bourquin, J.P.1
-
7
-
-
0029040851
-
Expression of erythroid-specific genes in acute megakaryoblastic leukaemia and transient myeloproliferative disorder in Down's syndrome
-
Ito E, et al. Expression of erythroid-specific genes in acute megakaryoblastic leukaemia and transient myeloproliferative disorder in Down's syndrome. Br J Haematol. 1995;90(3):607-614.
-
(1995)
Br J Haematol
, vol.90
, Issue.3
, pp. 607-614
-
-
Ito, E.1
-
8
-
-
33745076542
-
A prospective study of the natural history of transient leukemia (TL) in neonates with Down syndrome (DS): Children's Oncology Group (COG) study POG-9481
-
Massey GV, et al. A prospective study of the natural history of transient leukemia (TL) in neonates with Down syndrome (DS): Children's Oncology Group (COG) study POG-9481. Blood. 2006; 107(12):4606-4613.
-
(2006)
Blood
, vol.107
, Issue.12
, pp. 4606-4613
-
-
Massey, G.V.1
-
9
-
-
42449104896
-
Treatment and prognostic impact of transient leukemia in neonates with Down syndrome
-
Klusmann JH, et al. Treatment and prognostic impact of transient leukemia in neonates with Down syndrome. Blood. 2008;111(6):2991-2998.
-
(2008)
Blood
, vol.111
, Issue.6
, pp. 2991-2998
-
-
Klusmann, J.H.1
-
10
-
-
0036727413
-
Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome
-
Wechsler J, et al. Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nat Genet. 2002;32(1):148-152.
-
(2002)
Nat Genet
, vol.32
, Issue.1
, pp. 148-152
-
-
Wechsler, J.1
-
11
-
-
0038142390
-
Mutagenesis of GATA1 is an initiating event in Down syndrome leukemogenesis
-
Mundschau G, Gurbuxani S, Gamis AS, Greene ME, Arceci RJ, Crispino JD. Mutagenesis of GATA1 is an initiating event in Down syndrome leukemogenesis. Blood. 2003;101(11):4298-4300.
-
(2003)
Blood
, vol.101
, Issue.11
, pp. 4298-4300
-
-
Mundschau, G.1
Gurbuxani, S.2
Gamis, A.S.3
Greene, M.E.4
Arceci, R.J.5
Crispino, J.D.6
-
12
-
-
0038142350
-
GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome
-
Hitzler JK, Cheung J, Li Y, Scherer SW, Zipursky A. GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome. Blood. 2003;101(11):4301-4304.
-
(2003)
Blood
, vol.101
, Issue.11
, pp. 4301-4304
-
-
Hitzler, J.K.1
Cheung, J.2
Li, Y.3
Scherer, S.W.4
Zipursky, A.5
-
13
-
-
12144287045
-
Natural history of GATA1 mutations in Down syndrome
-
Ahmed M, et al. Natural history of GATA1 mutations in Down syndrome. Blood. 2004;103(7):2480-2489.
-
(2004)
Blood
, vol.103
, Issue.7
, pp. 2480-2489
-
-
Ahmed, M.1
-
14
-
-
0037906527
-
Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder
-
Groet J, et al. Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder. Lancet. 2003;361(9369):1617-1620.
-
(2003)
Lancet
, vol.361
, Issue.9369
, pp. 1617-1620
-
-
Groet, J.1
-
15
-
-
0042243593
-
Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21
-
Rainis L, et al. Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21. Blood. 2003;102(3):981-986.
-
(2003)
Blood
, vol.102
, Issue.3
, pp. 981-986
-
-
Rainis, L.1
-
16
-
-
0030926006
-
A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development
-
Shivdasani RA, Fujiwara Y, McDevitt MA, Orkin SH. A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development. EMBO J. 1997;16(13):3965-3973.
-
(1997)
EMBO J
, vol.16
, Issue.13
, pp. 3965-3973
-
-
Shivdasani, R.A.1
Fujiwara, Y.2
McDevitt, M.A.3
Orkin, S.H.4
-
17
-
-
0033134831
-
Consequences of GATA-1 deficiency in megakaryocytes and platelets
-
Vyas P, Ault K, Jackson CW, Orkin SH, Shivdasani RA. Consequences of GATA-1 deficiency in megakaryocytes and platelets. Blood. 1999;93(9):2867-2875.
-
(1999)
Blood
, vol.93
, Issue.9
, pp. 2867-2875
-
-
Vyas, P.1
Ault, K.2
Jackson, C.W.3
Orkin, S.H.4
Shivdasani, R.A.5
-
18
-
-
1842422317
-
The GATA1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down syndrome
-
Harigae H, Xu G, Sugawara T, Ishikawa I, Toki T, Ito E. The GATA1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down syndrome. Blood. 2004;103(8):3242-3243.
-
(2004)
Blood
, vol.103
, Issue.8
, pp. 3242-3243
-
-
Harigae, H.1
Xu, G.2
Sugawara, T.3
Ishikawa, I.4
Toki, T.5
Ito, E.6
-
19
-
-
33745579586
-
An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis
-
Hollanda LM, et al. An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis. Nat Genet. 2006;38(7):807-812.
-
(2006)
Nat Genet
, vol.38
, Issue.7
, pp. 807-812
-
-
Hollanda, L.M.1
-
20
-
-
84863554398
-
Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia
-
Sankaran VG, et al. Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia. J Clin Invest. 2012;122(7):2439-2443.
-
(2012)
J Clin Invest
, vol.122
, Issue.7
, pp. 2439-2443
-
-
Sankaran, V.G.1
-
21
-
-
20044381309
-
Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1
-
Li Z, Godinho FJ, Klusmann JH, Garriga-Canut M, Yu C, Orkin SH. Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1. Nat Genet. 2005; 37(6):613-619.
-
(2005)
Nat Genet
, vol.37
, Issue.6
, pp. 613-619
-
-
Li, Z.1
Godinho, F.J.2
Klusmann, J.H.3
Garriga-Canut, M.4
Yu, C.5
Orkin, S.H.6
-
22
-
-
34848896359
-
Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy
-
Pronk CJ, et al. Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. Cell Stem Cell. 2007; 1(4):428-442.
-
(2007)
Cell Stem Cell
, vol.1
, Issue.4
, pp. 428-442
-
-
Pronk, C.J.1
-
23
-
-
0034665904
-
Interferon-alpha directly represses megakaryopoiesis by inhibiting thrombopoietin-induced signaling through induction of SOCS-1
-
Wang Q, Miyakawa Y, Fox N, Kaushansky K. Interferon-alpha directly represses megakaryopoiesis by inhibiting thrombopoietin-induced signaling through induction of SOCS-1. Blood. 2000; 96(6):2093-2099.
-
(2000)
Blood
, vol.96
, Issue.6
, pp. 2093-2099
-
-
Wang, Q.1
Miyakawa, Y.2
Fox, N.3
Kaushansky, K.4
-
24
-
-
54049141336
-
Pegylated interferon-alfa-2a induces complete hematologic and molecular responses with low toxicity in polycythemia vera
-
Kiladjian JJ, et al. Pegylated interferon-alfa-2a induces complete hematologic and molecular responses with low toxicity in polycythemia vera. Blood. 2008;112(8):3065-3072.
-
(2008)
Blood
, vol.112
, Issue.8
, pp. 3065-3072
-
-
Kiladjian, J.J.1
-
25
-
-
0025189361
-
Recombinant interferon-alpha, but not interferon-gamma is effective therapy for essential thrombocythemia
-
Abegg-Werter MJ, Raemaekers JM, de Pauw BE, Haanen C. Recombinant interferon-alpha, but not interferon-gamma is effective therapy for essential thrombocythemia. Blut. 1990;60(1):37-40.
-
(1990)
Blut
, vol.60
, Issue.1
, pp. 37-40
-
-
Abegg-Werter, M.J.1
Raemaekers, J.M.2
De Pauw, B.E.3
Haanen, C.4
-
26
-
-
34548140132
-
The role of interferon-alpha in the treatment of chronic myeloid leukemia
-
Kujawski LA, Talpaz M. The role of interferon-alpha in the treatment of chronic myeloid leukemia. Cytokine Growth Factor Rev. 2007;18(5-6):459-471.
-
(2007)
Cytokine Growth Factor Rev
, vol.18
, Issue.5-6
, pp. 459-471
-
-
Kujawski, L.A.1
Talpaz, M.2
-
27
-
-
0028070714
-
Functional role of type i and type II interferons in antiviral defense
-
Muller U, et al. Functional role of type I and type II interferons in antiviral defense. Science. 1994; 264(5167):1918-1921.
-
(1994)
Science
, vol.264
, Issue.5167
, pp. 1918-1921
-
-
Muller, U.1
-
28
-
-
82755161998
-
Expression and functionality of type i interferon receptor in the megakaryocytic lineage
-
Negrotto S, et al. Expression and functionality of type I interferon receptor in the megakaryocytic lineage. J Thromb Haemost. 2011;9(12):2477-2485.
-
(2011)
J Thromb Haemost
, vol.9
, Issue.12
, pp. 2477-2485
-
-
Negrotto, S.1
-
29
-
-
84867736794
-
Combinatorial assembly of developmental stage-specific enhancers controls gene expression programs during human erythropoiesis
-
Xu J, et al. Combinatorial assembly of developmental stage-specific enhancers controls gene expression programs during human erythropoiesis. Dev Cell. 2012;23(4):796-811.
-
(2012)
Dev Cell
, vol.23
, Issue.4
, pp. 796-811
-
-
Xu, J.1
-
30
-
-
0027361463
-
Targeted disruption of IRF-1 or IRF-2 results in abnormal type i IFN gene induction and aberrant lymphocyte development
-
Matsuyama T, et al. Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development. Cell. 1993;75(1):83-97.
-
(1993)
Cell
, vol.75
, Issue.1
, pp. 83-97
-
-
Matsuyama, T.1
-
31
-
-
66149115277
-
IFNα activates dormant haematopoietic stem cells in vivo
-
Essers MA, et al. IFNα activates dormant haematopoietic stem cells in vivo. Nature. 2009; 458(7240):904-908.
-
(2009)
Nature
, vol.458
, Issue.7240
, pp. 904-908
-
-
Essers, M.A.1
-
32
-
-
84864805939
-
Proteomic cornerstones of hematopoietic stem cell differentiation: Distinct signatures of multipotent progenitors and myeloid committed cells
-
Klimmeck D, Hansson J, Raffel S, Vakhrushev SY, Trumpp A, Krijgsveld J. Proteomic cornerstones of hematopoietic stem cell differentiation: distinct signatures of multipotent progenitors and myeloid committed cells. Mol Cell Proteomics. 2012; 11(8):286-302.
-
(2012)
Mol Cell Proteomics
, vol.11
, Issue.8
, pp. 286-302
-
-
Klimmeck, D.1
Hansson, J.2
Raffel, S.3
Vakhrushev, S.Y.4
Trumpp, A.5
Krijgsveld, J.6
-
33
-
-
34248592079
-
Toll-like receptor 3 ligand-induced antiviral response in mouse osteoblastic cells
-
Nakamura K, Deyama Y, Yoshimura Y, Suzuki K, Morita M. Toll-like receptor 3 ligand-induced antiviral response in mouse osteoblastic cells. Int J Mol Med. 2007;19(5):771-775.
-
(2007)
Int J Mol Med
, vol.19
, Issue.5
, pp. 771-775
-
-
Nakamura, K.1
Deyama, Y.2
Yoshimura, Y.3
Suzuki, K.4
Morita, M.5
-
34
-
-
0037129205
-
RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β
-
Takayanagi H, et al. RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β. Nature. 2002;416(6882):744-749.
-
(2002)
Nature
, vol.416
, Issue.6882
, pp. 744-749
-
-
Takayanagi, H.1
-
35
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell JE Jr, Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science. 1994;264(5164):1415-1421.
-
(1994)
Science
, vol.264
, Issue.5164
, pp. 1415-1421
-
-
Darnell Jr., J.E.1
Kerr, I.M.2
Stark, G.R.3
-
36
-
-
0029923456
-
Formation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-α
-
Li X, Leung S, Qureshi S, Darnell JE Jr, Stark GR. Formation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-α. J Biol Chem. 1996; 271(10):5790-5794.
-
(1996)
J Biol Chem
, vol.271
, Issue.10
, pp. 5790-5794
-
-
Li, X.1
Leung, S.2
Qureshi, S.3
Darnell Jr., J.E.4
Stark, G.R.5
-
37
-
-
23044499360
-
Differential requirements for the activation domain and FOGinteraction surface of GATA-1 in megakaryocyte gene expression and development
-
Muntean AG, Crispino JD. Differential requirements for the activation domain and FOGinteraction surface of GATA-1 in megakaryocyte gene expression and development. Blood. 2005; 106(4):1223-1231.
-
(2005)
Blood
, vol.106
, Issue.4
, pp. 1223-1231
-
-
Muntean, A.G.1
Crispino, J.D.2
-
38
-
-
36849016548
-
STAT1 promotes megakaryopoiesis downstream of GATA-1 in mice
-
Huang Z, Richmond TD, Muntean AG, Barber DL, Weiss MJ, Crispino JD. STAT1 promotes megakaryopoiesis downstream of GATA-1 in mice. J Clin Invest. 2007;117(12):3890-3899.
-
(2007)
J Clin Invest
, vol.117
, Issue.12
, pp. 3890-3899
-
-
Huang, Z.1
Richmond, T.D.2
Muntean, A.G.3
Barber, D.L.4
Weiss, M.J.5
Crispino, J.D.6
-
39
-
-
77955870488
-
Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis
-
Klusmann JH, et al. Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis. Genes Deve. 2010; 24(15):1659-1672.
-
(2010)
Genes Deve
, vol.24
, Issue.15
, pp. 1659-1672
-
-
Klusmann, J.H.1
-
40
-
-
80051799269
-
Neonatal and adult megakaryopoiesis
-
Liu ZJ, Sola-Visner M. Neonatal and adult megakaryopoiesis. Curr Opin Hematol. 2011;18(5):330-337.
-
(2011)
Curr Opin Hematol
, vol.18
, Issue.5
, pp. 330-337
-
-
Liu, Z.J.1
Sola-Visner, M.2
-
41
-
-
79959232873
-
Recombinant interferon-α may retard progression of early primary myelofibrosis: A preliminary report
-
Silver RT, Vandris K, Goldman JJ. Recombinant interferon-α may retard progression of early primary myelofibrosis: a preliminary report. Blood. 2011; 117(24):6669-6672.
-
(2011)
Blood
, vol.117
, Issue.24
, pp. 6669-6672
-
-
Silver, R.T.1
Vandris, K.2
Goldman, J.J.3
-
42
-
-
80052022462
-
Cistrome: An integrative platform for transcriptional regulation studies
-
Liu T, et al. Cistrome: an integrative platform for transcriptional regulation studies. Genome Biol. 2011;12(8):R83.
-
(2011)
Genome Biol
, vol.12
, Issue.8
-
-
Liu, T.1
-
43
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian A, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A. 2005;102(43):15545-15550.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.43
, pp. 15545-15550
-
-
Subramanian, A.1
-
44
-
-
0036211034
-
Interferon-α activates multiple STAT signals and down-regulates c-Met in primary human hepatocytes
-
Radaeva S, et al. Interferon-α activates multiple STAT signals and down-regulates c-Met in primary human hepatocytes. Gastroenterology. 2002; 122(4):1020-1034.
-
(2002)
Gastroenterology
, vol.122
, Issue.4
, pp. 1020-1034
-
-
Radaeva, S.1
-
45
-
-
0035194167
-
Altered cellular mRNA levels in human cytomegalovirus- infected fibroblasts: Viral block to the accumulation of antiviral mRNAs
-
Browne EP, Wing B, Coleman D, Shenk T. Altered cellular mRNA levels in human cytomegalovirus- infected fibroblasts: viral block to the accumulation of antiviral mRNAs. J Virol. 2001; 75(24):12319-12330.
-
(2001)
J Virol
, vol.75
, Issue.24
, pp. 12319-12330
-
-
Browne, E.P.1
Wing, B.2
Coleman, D.3
Shenk, T.4
|