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Volumn 123, Issue 8, 2013, Pages 3292-3304

Developmental differences in IFN signaling affect GATA1s-induced megakaryocyte hyperproliferation

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ALPHA INTERFERON RECEPTOR; ALPHA INTERFERON RECEPTOR 1; INTERFERON; TRANSCRIPTION FACTOR GATA 1; UNCLASSIFIED DRUG;

EID: 84881256257     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI40609     Document Type: Article
Times cited : (32)

References (45)
  • 1
    • 0023459992 scopus 로고
    • Megakaryoblastic leukemia and Down's syndrome: A review
    • Zipursky A, Peeters M, Poon A. Megakaryoblastic leukemia and Down's syndrome: a review. Pediatr Hematol Oncol. 1987;4(3):211-230.
    • (1987) Pediatr Hematol Oncol , vol.4 , Issue.3 , pp. 211-230
    • Zipursky, A.1    Peeters, M.2    Poon, A.3
  • 2
    • 0026574340 scopus 로고
    • Down syndrome and leukemia
    • Robison LL. Down syndrome and leukemia. Leukemia. 1992;6(Suppl. 1):5-7.
    • (1992) Leukemia , vol.6 , Issue.SUPPL. 1 , pp. 5-7
    • Robison, L.L.1
  • 4
    • 0032941980 scopus 로고    scopus 로고
    • Transient myeloproliferative disorder (transient leukemia) and hematologic manifestations of Down syndrome
    • vii.
    • Zipursky A, Brown EJ, Christensen H, Doyle J. Transient myeloproliferative disorder (transient leukemia) and hematologic manifestations of Down syndrome. Clin Lab Med. 1999;19(1):157-167, vii.
    • (1999) Clin Lab Med , vol.19 , Issue.1 , pp. 157-167
    • Zipursky, A.1    Brown, E.J.2    Christensen, H.3    Doyle, J.4
  • 5
    • 18944363334 scopus 로고    scopus 로고
    • Immunophenotype of Down syndrome acute myeloid leukemia and transient myeloproliferative disease differs significantly from other diseases with morphologically identical or similar blasts
    • Langebrake C, Creutzig U, Reinhardt D. Immunophenotype of Down syndrome acute myeloid leukemia and transient myeloproliferative disease differs significantly from other diseases with morphologically identical or similar blasts. Klin Padiatr. 2005; 217(3):126-134.
    • (2005) Klin Padiatr , vol.217 , Issue.3 , pp. 126-134
    • Langebrake, C.1    Creutzig, U.2    Reinhardt, D.3
  • 6
    • 33644759290 scopus 로고    scopus 로고
    • Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling
    • Bourquin JP, et al. Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling. Proc Natl Acad Sci U S A. 2006;103(9):3339-3344.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.9 , pp. 3339-3344
    • Bourquin, J.P.1
  • 7
    • 0029040851 scopus 로고
    • Expression of erythroid-specific genes in acute megakaryoblastic leukaemia and transient myeloproliferative disorder in Down's syndrome
    • Ito E, et al. Expression of erythroid-specific genes in acute megakaryoblastic leukaemia and transient myeloproliferative disorder in Down's syndrome. Br J Haematol. 1995;90(3):607-614.
    • (1995) Br J Haematol , vol.90 , Issue.3 , pp. 607-614
    • Ito, E.1
  • 8
    • 33745076542 scopus 로고    scopus 로고
    • A prospective study of the natural history of transient leukemia (TL) in neonates with Down syndrome (DS): Children's Oncology Group (COG) study POG-9481
    • Massey GV, et al. A prospective study of the natural history of transient leukemia (TL) in neonates with Down syndrome (DS): Children's Oncology Group (COG) study POG-9481. Blood. 2006; 107(12):4606-4613.
    • (2006) Blood , vol.107 , Issue.12 , pp. 4606-4613
    • Massey, G.V.1
  • 9
    • 42449104896 scopus 로고    scopus 로고
    • Treatment and prognostic impact of transient leukemia in neonates with Down syndrome
    • Klusmann JH, et al. Treatment and prognostic impact of transient leukemia in neonates with Down syndrome. Blood. 2008;111(6):2991-2998.
    • (2008) Blood , vol.111 , Issue.6 , pp. 2991-2998
    • Klusmann, J.H.1
  • 10
    • 0036727413 scopus 로고    scopus 로고
    • Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome
    • Wechsler J, et al. Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nat Genet. 2002;32(1):148-152.
    • (2002) Nat Genet , vol.32 , Issue.1 , pp. 148-152
    • Wechsler, J.1
  • 12
    • 0038142350 scopus 로고    scopus 로고
    • GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome
    • Hitzler JK, Cheung J, Li Y, Scherer SW, Zipursky A. GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome. Blood. 2003;101(11):4301-4304.
    • (2003) Blood , vol.101 , Issue.11 , pp. 4301-4304
    • Hitzler, J.K.1    Cheung, J.2    Li, Y.3    Scherer, S.W.4    Zipursky, A.5
  • 13
    • 12144287045 scopus 로고    scopus 로고
    • Natural history of GATA1 mutations in Down syndrome
    • Ahmed M, et al. Natural history of GATA1 mutations in Down syndrome. Blood. 2004;103(7):2480-2489.
    • (2004) Blood , vol.103 , Issue.7 , pp. 2480-2489
    • Ahmed, M.1
  • 14
    • 0037906527 scopus 로고    scopus 로고
    • Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder
    • Groet J, et al. Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder. Lancet. 2003;361(9369):1617-1620.
    • (2003) Lancet , vol.361 , Issue.9369 , pp. 1617-1620
    • Groet, J.1
  • 15
    • 0042243593 scopus 로고    scopus 로고
    • Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21
    • Rainis L, et al. Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21. Blood. 2003;102(3):981-986.
    • (2003) Blood , vol.102 , Issue.3 , pp. 981-986
    • Rainis, L.1
  • 16
    • 0030926006 scopus 로고    scopus 로고
    • A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development
    • Shivdasani RA, Fujiwara Y, McDevitt MA, Orkin SH. A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development. EMBO J. 1997;16(13):3965-3973.
    • (1997) EMBO J , vol.16 , Issue.13 , pp. 3965-3973
    • Shivdasani, R.A.1    Fujiwara, Y.2    McDevitt, M.A.3    Orkin, S.H.4
  • 17
    • 0033134831 scopus 로고    scopus 로고
    • Consequences of GATA-1 deficiency in megakaryocytes and platelets
    • Vyas P, Ault K, Jackson CW, Orkin SH, Shivdasani RA. Consequences of GATA-1 deficiency in megakaryocytes and platelets. Blood. 1999;93(9):2867-2875.
    • (1999) Blood , vol.93 , Issue.9 , pp. 2867-2875
    • Vyas, P.1    Ault, K.2    Jackson, C.W.3    Orkin, S.H.4    Shivdasani, R.A.5
  • 18
    • 1842422317 scopus 로고    scopus 로고
    • The GATA1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down syndrome
    • Harigae H, Xu G, Sugawara T, Ishikawa I, Toki T, Ito E. The GATA1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down syndrome. Blood. 2004;103(8):3242-3243.
    • (2004) Blood , vol.103 , Issue.8 , pp. 3242-3243
    • Harigae, H.1    Xu, G.2    Sugawara, T.3    Ishikawa, I.4    Toki, T.5    Ito, E.6
  • 19
    • 33745579586 scopus 로고    scopus 로고
    • An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis
    • Hollanda LM, et al. An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis. Nat Genet. 2006;38(7):807-812.
    • (2006) Nat Genet , vol.38 , Issue.7 , pp. 807-812
    • Hollanda, L.M.1
  • 20
    • 84863554398 scopus 로고    scopus 로고
    • Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia
    • Sankaran VG, et al. Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia. J Clin Invest. 2012;122(7):2439-2443.
    • (2012) J Clin Invest , vol.122 , Issue.7 , pp. 2439-2443
    • Sankaran, V.G.1
  • 21
    • 20044381309 scopus 로고    scopus 로고
    • Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1
    • Li Z, Godinho FJ, Klusmann JH, Garriga-Canut M, Yu C, Orkin SH. Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1. Nat Genet. 2005; 37(6):613-619.
    • (2005) Nat Genet , vol.37 , Issue.6 , pp. 613-619
    • Li, Z.1    Godinho, F.J.2    Klusmann, J.H.3    Garriga-Canut, M.4    Yu, C.5    Orkin, S.H.6
  • 22
    • 34848896359 scopus 로고    scopus 로고
    • Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy
    • Pronk CJ, et al. Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. Cell Stem Cell. 2007; 1(4):428-442.
    • (2007) Cell Stem Cell , vol.1 , Issue.4 , pp. 428-442
    • Pronk, C.J.1
  • 23
    • 0034665904 scopus 로고    scopus 로고
    • Interferon-alpha directly represses megakaryopoiesis by inhibiting thrombopoietin-induced signaling through induction of SOCS-1
    • Wang Q, Miyakawa Y, Fox N, Kaushansky K. Interferon-alpha directly represses megakaryopoiesis by inhibiting thrombopoietin-induced signaling through induction of SOCS-1. Blood. 2000; 96(6):2093-2099.
    • (2000) Blood , vol.96 , Issue.6 , pp. 2093-2099
    • Wang, Q.1    Miyakawa, Y.2    Fox, N.3    Kaushansky, K.4
  • 24
    • 54049141336 scopus 로고    scopus 로고
    • Pegylated interferon-alfa-2a induces complete hematologic and molecular responses with low toxicity in polycythemia vera
    • Kiladjian JJ, et al. Pegylated interferon-alfa-2a induces complete hematologic and molecular responses with low toxicity in polycythemia vera. Blood. 2008;112(8):3065-3072.
    • (2008) Blood , vol.112 , Issue.8 , pp. 3065-3072
    • Kiladjian, J.J.1
  • 25
    • 0025189361 scopus 로고
    • Recombinant interferon-alpha, but not interferon-gamma is effective therapy for essential thrombocythemia
    • Abegg-Werter MJ, Raemaekers JM, de Pauw BE, Haanen C. Recombinant interferon-alpha, but not interferon-gamma is effective therapy for essential thrombocythemia. Blut. 1990;60(1):37-40.
    • (1990) Blut , vol.60 , Issue.1 , pp. 37-40
    • Abegg-Werter, M.J.1    Raemaekers, J.M.2    De Pauw, B.E.3    Haanen, C.4
  • 26
    • 34548140132 scopus 로고    scopus 로고
    • The role of interferon-alpha in the treatment of chronic myeloid leukemia
    • Kujawski LA, Talpaz M. The role of interferon-alpha in the treatment of chronic myeloid leukemia. Cytokine Growth Factor Rev. 2007;18(5-6):459-471.
    • (2007) Cytokine Growth Factor Rev , vol.18 , Issue.5-6 , pp. 459-471
    • Kujawski, L.A.1    Talpaz, M.2
  • 27
    • 0028070714 scopus 로고
    • Functional role of type i and type II interferons in antiviral defense
    • Muller U, et al. Functional role of type I and type II interferons in antiviral defense. Science. 1994; 264(5167):1918-1921.
    • (1994) Science , vol.264 , Issue.5167 , pp. 1918-1921
    • Muller, U.1
  • 28
    • 82755161998 scopus 로고    scopus 로고
    • Expression and functionality of type i interferon receptor in the megakaryocytic lineage
    • Negrotto S, et al. Expression and functionality of type I interferon receptor in the megakaryocytic lineage. J Thromb Haemost. 2011;9(12):2477-2485.
    • (2011) J Thromb Haemost , vol.9 , Issue.12 , pp. 2477-2485
    • Negrotto, S.1
  • 29
    • 84867736794 scopus 로고    scopus 로고
    • Combinatorial assembly of developmental stage-specific enhancers controls gene expression programs during human erythropoiesis
    • Xu J, et al. Combinatorial assembly of developmental stage-specific enhancers controls gene expression programs during human erythropoiesis. Dev Cell. 2012;23(4):796-811.
    • (2012) Dev Cell , vol.23 , Issue.4 , pp. 796-811
    • Xu, J.1
  • 30
    • 0027361463 scopus 로고
    • Targeted disruption of IRF-1 or IRF-2 results in abnormal type i IFN gene induction and aberrant lymphocyte development
    • Matsuyama T, et al. Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development. Cell. 1993;75(1):83-97.
    • (1993) Cell , vol.75 , Issue.1 , pp. 83-97
    • Matsuyama, T.1
  • 31
    • 66149115277 scopus 로고    scopus 로고
    • IFNα activates dormant haematopoietic stem cells in vivo
    • Essers MA, et al. IFNα activates dormant haematopoietic stem cells in vivo. Nature. 2009; 458(7240):904-908.
    • (2009) Nature , vol.458 , Issue.7240 , pp. 904-908
    • Essers, M.A.1
  • 32
    • 84864805939 scopus 로고    scopus 로고
    • Proteomic cornerstones of hematopoietic stem cell differentiation: Distinct signatures of multipotent progenitors and myeloid committed cells
    • Klimmeck D, Hansson J, Raffel S, Vakhrushev SY, Trumpp A, Krijgsveld J. Proteomic cornerstones of hematopoietic stem cell differentiation: distinct signatures of multipotent progenitors and myeloid committed cells. Mol Cell Proteomics. 2012; 11(8):286-302.
    • (2012) Mol Cell Proteomics , vol.11 , Issue.8 , pp. 286-302
    • Klimmeck, D.1    Hansson, J.2    Raffel, S.3    Vakhrushev, S.Y.4    Trumpp, A.5    Krijgsveld, J.6
  • 33
    • 34248592079 scopus 로고    scopus 로고
    • Toll-like receptor 3 ligand-induced antiviral response in mouse osteoblastic cells
    • Nakamura K, Deyama Y, Yoshimura Y, Suzuki K, Morita M. Toll-like receptor 3 ligand-induced antiviral response in mouse osteoblastic cells. Int J Mol Med. 2007;19(5):771-775.
    • (2007) Int J Mol Med , vol.19 , Issue.5 , pp. 771-775
    • Nakamura, K.1    Deyama, Y.2    Yoshimura, Y.3    Suzuki, K.4    Morita, M.5
  • 34
    • 0037129205 scopus 로고    scopus 로고
    • RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β
    • Takayanagi H, et al. RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β. Nature. 2002;416(6882):744-749.
    • (2002) Nature , vol.416 , Issue.6882 , pp. 744-749
    • Takayanagi, H.1
  • 35
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell JE Jr, Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science. 1994;264(5164):1415-1421.
    • (1994) Science , vol.264 , Issue.5164 , pp. 1415-1421
    • Darnell Jr., J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 36
    • 0029923456 scopus 로고    scopus 로고
    • Formation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-α
    • Li X, Leung S, Qureshi S, Darnell JE Jr, Stark GR. Formation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-α. J Biol Chem. 1996; 271(10):5790-5794.
    • (1996) J Biol Chem , vol.271 , Issue.10 , pp. 5790-5794
    • Li, X.1    Leung, S.2    Qureshi, S.3    Darnell Jr., J.E.4    Stark, G.R.5
  • 37
    • 23044499360 scopus 로고    scopus 로고
    • Differential requirements for the activation domain and FOGinteraction surface of GATA-1 in megakaryocyte gene expression and development
    • Muntean AG, Crispino JD. Differential requirements for the activation domain and FOGinteraction surface of GATA-1 in megakaryocyte gene expression and development. Blood. 2005; 106(4):1223-1231.
    • (2005) Blood , vol.106 , Issue.4 , pp. 1223-1231
    • Muntean, A.G.1    Crispino, J.D.2
  • 39
    • 77955870488 scopus 로고    scopus 로고
    • Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis
    • Klusmann JH, et al. Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis. Genes Deve. 2010; 24(15):1659-1672.
    • (2010) Genes Deve , vol.24 , Issue.15 , pp. 1659-1672
    • Klusmann, J.H.1
  • 40
    • 80051799269 scopus 로고    scopus 로고
    • Neonatal and adult megakaryopoiesis
    • Liu ZJ, Sola-Visner M. Neonatal and adult megakaryopoiesis. Curr Opin Hematol. 2011;18(5):330-337.
    • (2011) Curr Opin Hematol , vol.18 , Issue.5 , pp. 330-337
    • Liu, Z.J.1    Sola-Visner, M.2
  • 41
    • 79959232873 scopus 로고    scopus 로고
    • Recombinant interferon-α may retard progression of early primary myelofibrosis: A preliminary report
    • Silver RT, Vandris K, Goldman JJ. Recombinant interferon-α may retard progression of early primary myelofibrosis: a preliminary report. Blood. 2011; 117(24):6669-6672.
    • (2011) Blood , vol.117 , Issue.24 , pp. 6669-6672
    • Silver, R.T.1    Vandris, K.2    Goldman, J.J.3
  • 42
    • 80052022462 scopus 로고    scopus 로고
    • Cistrome: An integrative platform for transcriptional regulation studies
    • Liu T, et al. Cistrome: an integrative platform for transcriptional regulation studies. Genome Biol. 2011;12(8):R83.
    • (2011) Genome Biol , vol.12 , Issue.8
    • Liu, T.1
  • 43
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A. 2005;102(43):15545-15550.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.43 , pp. 15545-15550
    • Subramanian, A.1
  • 44
    • 0036211034 scopus 로고    scopus 로고
    • Interferon-α activates multiple STAT signals and down-regulates c-Met in primary human hepatocytes
    • Radaeva S, et al. Interferon-α activates multiple STAT signals and down-regulates c-Met in primary human hepatocytes. Gastroenterology. 2002; 122(4):1020-1034.
    • (2002) Gastroenterology , vol.122 , Issue.4 , pp. 1020-1034
    • Radaeva, S.1
  • 45
    • 0035194167 scopus 로고    scopus 로고
    • Altered cellular mRNA levels in human cytomegalovirus- infected fibroblasts: Viral block to the accumulation of antiviral mRNAs
    • Browne EP, Wing B, Coleman D, Shenk T. Altered cellular mRNA levels in human cytomegalovirus- infected fibroblasts: viral block to the accumulation of antiviral mRNAs. J Virol. 2001; 75(24):12319-12330.
    • (2001) J Virol , vol.75 , Issue.24 , pp. 12319-12330
    • Browne, E.P.1    Wing, B.2    Coleman, D.3    Shenk, T.4


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