β,β-Carotene 15,15#-monooxygenase and its substrate β-carotene modulate migration and invasion in colorectal carcinoma cells

American Journal of Clinical Nutrition

Volumn 98, Issue 2, 2013, Pages 413-422

  Pham, Diep Ngoc Thi ^a   Leclerc, Daniel ^a   Lévesque, Nancy ^a   Deng, Liyuan ^a   Rozen, Rima ^a  

^a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BETA CAROTENE; BETA CAROTENE 15,15' MONOOXYGENASE; FOLIC ACID; MATRILYSIN; MATRIX METALLOPROTEINASE 28; METALLOPROTEINASE; RETINOIC ACID; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CARCINOMA CELL; CELL INVASION; CELL MIGRATION; CELL VIABILITY; COLON CARCINOMA; COLORECTAL CARCINOMA; COMPARATIVE STUDY; CONTROLLED STUDY; CPG ISLAND; DNA FLANKING REGION; DNA METHYLATION; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; METASTASIS POTENTIAL; PHENOTYPE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BETA CAROTENE; BETA-CAROTENE 15,15'-MONOOXYGENASE; CELL LINE, TUMOR; COLON; COLORECTAL NEOPLASMS; FOLIC ACID; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTESTINES; MATRIX METALLOPROTEINASE 7; MATRIX METALLOPROTEINASES, SECRETED; RNA, MESSENGER; RNA, SMALL INTERFERING; TRETINOIN; UP-REGULATION;

EID: 84881255289     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.113.060996     Document Type: Article

References (47)

1. Thomson CA, Thomson PA. Fruit and vegetable intake and breast cancer risk: a case for subtype-specific risk? J Natl Cancer Inst 2013; 105:164-5.
2. Reiss R, Johnston J, Tucker K, DeSesso JM, Keen CL. Estimation of cancer risks and benefits associated with a potential increased consumption of fruits and vegetables. Food Chem Toxicol 2012;50: 4421-7.
3. Takata Y, Xiang Y-B, Yang G, Li H, Gao J, Cai H, Gao Y-T, Zheng W, Shu X-O. Intakes of fruits, vegetables, and related vitamins and lung cancer risk: results from the Shanghai Men's Health Study (2002- 2009). Nutr Cancer 2013;65:51-61.
4. Jung S,Wu K, Giovannucci E, Spiegelman D,WillettWC, Smith-Warner SA. Carotenoid intake and risk of colorectal adenomas in a cohort of male health professionals. Cancer Causes Control 2013;24:705-17.
5. Amir H, Karas M, Giat J, Danilenko M, Levy R, Yermiahu T, Levy J, Sharoni Y. Lycopene and 1,25-dihydroxyvitamin D3 cooperate in the inhibition of cell cycle progression and induction of differentiation in HL-60 leukemic cells. Nutr Cancer 1999;33:105-12.
6. Olson JA, Hayaishi O. The enzymatic cleavage of beta-carotene into vitamin A by soluble enzymes of rat liver and intestine. Proc Natl Acad Sci USA 1965;54:1364-70.
7. Goodman DS, Huang HS. Biosynthesis of vitamin A with rat intestinal enzymes. Science 1965;149:879-80.
8. Lindqvist A, Andersson S. Biochemical properties of purified recombinant human beta-carotene 15,15'-monooxygenase. J Biol Chem 2002;277:23942-8.
9. Curran S, Murray GI. Matrix metalloproteinases: molecular aspects of their roles in tumour invasion and metastasis. Eur J Cancer 2000;36: 1621-30.
10. Ellerbroek SM, Stack MS. Membrane associated matrix metalloproteinases in metastasis. Bioessays 1999;21:940-9.
11. Coussens LM, Fingleton B, Matrisian LM. Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 2002;295:2387- 92.
12. Newell KJ, Witty JP, Rodgers WH, Matrisian LM. Expression and localization of matrix-degrading metalloproteinases during colorectal tumorigenesis. Mol Carcinog 1994;10:199-206.
13. Kioi M, Yamamoto K, Higashi S, Koshikawa N, Fujita K, Miyazaki K. Matrilysin (MMP-7) induces homotypic adhesion of human colon cancer cells and enhances their metastatic potential in nude mouse model. Oncogene 2003;22:8662-70.
14. Yoshimoto M, Itoh F, Yamamoto H, Hinoda Y, Imai K, Yachi A. Expression of MMP-7(PUMP-1) mRNA in human colorectal cancers. Int J Cancer 1993;54:614-8.
15. Witty JP, McDonnell S, Newell KJ, Cannon P, Navre M, Tressler RJ, Matrisian LM. Modulation of matrilysin levels in colon carcinoma cell lines affects tumorigenicity in vivo. Cancer Res 1994;54:4805-12.
16. Yamamoto H, Itoh F, Senota A, Adachi Y, Yochimoto M, Endoh T, Hinoda Y, Imai K. Expression of matrix metalloproteinase matrilysin (MMP-7) was induced by activated Ki-ras via AP-1 activation in SW1417 colon cancer cells. J Clin Lab Anal 1995;9:297-301.
17. Marchenko GN, Strongin AY. MMP-28, a new human matrix metalloproteinase with an unusual cysteine-switch sequence is widely expressed in tumors. Gene 2001;265:87-93.
18. Jian P, Yanfang T, Zhuan Z, Jian W, Xueming Z, Jian N. MMP28 (epilysin) as a novel promoter of invasion and metastasis in gastric cancer. BMC Cancer 2011;11:200.
19. Protiva P, Mason JB, Liu Z, Hopkins ME, Nelson C, Marshall JR, Lambrecht RW, Pendyala S, Kopelovich L, Kim M, et al. Altered folate availability modifies the molecular environment of the human colorectum: implications for colorectal carcinogenesis. Cancer Prev Res (Phila) 2011;4:530-43.
20. Kennedy DA, Stern SJ, Moretti M, Stern SJ, Moretti M, Matok I, Sarkar M, Nickel C, Koren G. Folate intake and the risk of colorectal cancer: a systematic review and meta-analysis. Cancer Epidemiol 2011;35:2-10.
21. Goelz SE, Vogelstein B, Hamilton SR, Feinberg AP. Hypomethylation of DNA from benign and malignant human colon neoplasms. Science 1985;228:187-90.
22. Holliday R, Jeggo PA. Mechanisms for changing gene expression and their possible relationship to carcinogenesis. Cancer Surv 1985;4:557- 81.
23. Hammoud SS, Cairns BR, Jones DA. Epigenetic regulation of colon cancer and intestinal stem cells. Curr Opin Cell Biol 2013;25:177-83.
24. Costello JF, Plass C. Methylation matters. J Med Genet 2001;38:285- 303.
25. Knock E, Deng L, Wu Q, Leclerc D, Wang XL, Rozen R. Low dietary folate initiates intestinal tumors in mice, with altered expression of G2- M checkpoint regulators polo-like kinase 1 and cell division cycle 25c. Cancer Res 2006;66:10349-56.
26. Leclerc D, Cao Y, Deng L, Mikael LG, Wu Q, Rozen R. Differential gene expression and methylation in the retinoid/PPARA pathway and of tumor suppressors may modify intestinal tumorigenesis induced by low folate in mice. Mol Nutr Food Res 2013;57:686-97.
27. Devlin AM, Arning E, Bottiglieri T, Faraci FM, Rozen R, Lentz SR. Effect of MTHFR genotype on diet-induced hyperhomocysteinemia and vascular function in mice. Blood 2004;103:2624-9.
28. Bender R, Lange S. Adjusting for multiple testing-when and how. J Clin Epidemiol 2001;54:343-9.
29. Adachi Y, Itoh F, Yamamoto H, Iku S, Matsuno K, Arimura Y, Imai K. Retinoic acids reduce matrilysin (matrix metalloproteinase 7) and inhibit tumor cell invasion in human colon cancer. Tumour Biol 2001;22: 247-53.
30. Park EY, Wilder ET, Lane MA. Retinol inhibits the invasion of retinoic acid-resistant colon cancer cells in vitro and decreases matrix metalloproteinase mRNA, protein, and activity levels. Nutr Cancer 2007;57: 66-77.
31. Tsang KJ, Crowe DL. Retinoic acid and extracellular matrix inhibition of matrix metalloproteinase 9 expression is mediated by the mitogen activated protein kinase pathway. Int J Oncol 2001;18:369-74.
32. Pereda MP, Hopfner U, Pagotto U, Renner U, Uhi E, Arzt E, Missale C, Stalla GK. Retinoic acid stimulates meningioma cell adhesion to the extracellular matrix and inhibits invasion. Br J Cancer 1999;81:381-6.
33. Hendrix MJ, Wood WR, Seftor EA, Lotan D, Nakajima M, Misiorowski RL, Seftor RE, Stetler-Stevenson WG, Bevacqua SJ, Liotta LA, et al. Retinoic acid inhibition of human melanoma cell invasion through a reconstituted basement membrane and its relation to decreases in the expression of proteolytic enzymes and motility factor receptor. Cancer Res 1990;50:4121-30.
34. Schoenermark MP, Mitchell TI, Rutter JL, Reczek PR, Brinckerhoff CE. Retinoid-mediated suppression of tumor invasion and matrix metalloproteinase synthesis. Ann N Y Acad Sci 1999;878:466-86.
35. Gaire M, Magbanua Z, McDonnell S, McNeil L, Lovett DH, Matrisian LM. Structure and expression of the human gene for the matrix metalloproteinase matrilysin. J Biol Chem 1994;269:2032-40.
36. Adachi Y, Yamamoto H, Itoh F, Hinoda Y, Okada Y, Imai K. Contribution of matrilysin (MMP-7) to the metastatic pathway of human colorectal cancers. Gut 1999;45:252-8.
37. Masaki T, Matsuoka H, Sugiyama M, Abe N, Goto A, Sakamoto A, Atomi Y. Matrilysin (MMP-7) as a significant determinant of malignant potential of early invasive colorectal carcinomas. Br J Cancer 2001;84:1317-21.
38. Yang Q, Sakurai T, Kakudo K. Retinoid, retinoic acid receptor beta and breast cancer. Breast Cancer Res Treat 2002;76:167-73.
39. Wu Q, Chen YQ, Chen ZM, Chen F, Su WJ. Effects of retinoic acid on metastasis and its related proteins in gastric cancer cells in vivo and in vitro. Acta Pharmacol Sin 2002;23:835-41.
40. Chao TY, Jiang SY, Shyu RY, Yeh MY, Chu TM. All-trans retinoic acid decreases susceptibility of a gastric cancer cell line to lymphokine-activated killer cytotoxicity. Br J Cancer 1997;75: 1284-90.
41. von Lintig J, Wyss A. Molecular analysis of vitamin A formation: cloning and characterization of beta-carotene 15,15'-dioxygenases. Arch Biochem Biophys 2001;385:47-52.
42. Lawrance AK, Deng L, Rozen R. Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/+ mice. Gut 2009;58:805-11.
43. Kim YI. Folate and carcinogenesis: evidence, mechanisms, and implications. J Nutr Biochem 1999;10:66-88.
44. Kim YI. Folate and colorectal cancer: an evidence-based critical review. Mol Nutr Food Res 2007;51:267-92.
45. Mossman D, Kim KT, Scott RJ. Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists. BMC Cancer 2010;10:366.
46. Liang G, Gonzales FA, Jones PA, Orntoft TF, Thykjaer T. Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylaiton inhibitor 5-aza-2'-deoxycytidine. Cancer Res 2002;62:961-6.
47. Suzuki H, Gabrielson E, Chen W, Anbazhagan R, Van Engeland M, Weijenberg MP, Herman JG, Baylin SB. A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nat Genet 2002;31:141-9.