Differential gene expression and methylation in the retinoid/PPARA pathway and of tumor suppressors may modify intestinal tumorigenesis induced by low folate in mice

Molecular Nutrition and Food Research

Volumn 57, Issue 4, 2013, Pages 686-697

  Leclerc, Daniel ^a   Cao, Yuanhang ^a   Deng, Liyuan ^a   Mikael, Leonie G ^a   Wu, Qing ^a   Rozen, Rima ^a  

^a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

Carcinogenesis; DNA damage; Folate deficient diet; MTHFR; Oxidative stress

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE 1A1, MOUSE; BCMO1 PROTEIN, MOUSE; BETA CAROTENE 15,15' MONOOXYGENASE; BMP5 PROTEIN, MOUSE; BONE MORPHOGENETIC PROTEIN 5; CORNIFIED ENVELOPE LIKE PROLINE RICH PROTEIN; FOLIC ACID; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; RETINOID; SPRR2A PROTEIN, MOUSE;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BLOOD; C57BL MOUSE; CELL TRANSFORMATION; COLORECTAL TUMOR; DIET; DNA DAMAGE; DNA METHYLATION; DRUG EFFECT; FEMALE; FOLIC ACID DEFICIENCY; GENE EXPRESSION; GENETICS; GENOTYPE; INTESTINE; INTESTINE TUMOR; METABOLISM; MICROARRAY ANALYSIS; MOUSE; PATHOLOGY; TRANSGENIC MOUSE; UPREGULATION;

ALDEHYDE DEHYDROGENASE; ANIMALS; BETA-CAROTENE 15,15'-MONOOXYGENASE; BONE MORPHOGENETIC PROTEIN 5; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; CORNIFIED ENVELOPE PROLINE-RICH PROTEINS; DIET; DNA DAMAGE; DNA METHYLATION; FEMALE; FOLIC ACID; FOLIC ACID DEFICIENCY; GENE EXPRESSION; GENOTYPE; INTESTINAL NEOPLASMS; INTESTINES; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROARRAY ANALYSIS; PPAR ALPHA; RETINOIDS; UP-REGULATION;

MUS;

EID: 84875851710     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201200212     Document Type: Article

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