메뉴 건너뛰기




Volumn 64, Issue 2, 2013, Pages 189-200

Mutagenicity and DNA damage of bisphenol a and its structural analogues in HepG2 cells

Author keywords

Ames test; Bisphenols; Comet assay; Genotoxicity

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; AROCLOR 1254; ENVIRONMENTAL MUTAGEN; BENZHYDRYL DERIVATIVE; CYTOTOXIN; MUTAGENIC AGENT; PHENOL DERIVATIVE;

EID: 84881163285     PISSN: 00041254     EISSN: None     Source Type: Journal    
DOI: 10.2478/10004-1254-64-2013-2319     Document Type: Article
Times cited : (109)

References (61)
  • 3
    • 33745931394 scopus 로고    scopus 로고
    • Female sexual maturation and reproduction after prepubertal exposure to estrogens and endocrine disrupting chemicals: A review of rodent and human data
    • Rasier G, Toppari J, Parent AS, Bourguignon JP. Female sexual maturation and reproduction after prepubertal exposure to estrogens and endocrine disrupting chemicals: A review of rodent and human data. Mol Cell Endocrinol 2006;254:187-201.
    • (2006) Mol Cell Endocrinol , vol.254 , pp. 187-201
    • Rasier, G.1    Toppari, J.2    Parent, A.S.3    Bourguignon, J.P.4
  • 4
    • 84881147665 scopus 로고    scopus 로고
    • Screening Assessment for the Challenge Phenol, 4,4'-(1-methylethylidene) bis-(Bisphenol A). Chemical Abstracts Service Registry Number 80-05-7. [displayed 11 Sept]
    • Screening Assessment for the Challenge Phenol, 4,4'-(1-methylethylidene) bis-(Bisphenol A). Chemical Abstracts Service Registry Number 80-05-7. Environment Canada 2008 [displayed 11 Sept 2012]. Available at http://www.ec.gc. ca/ese-ees/3C756383-BEB3-45D5-B8D3-E8C800F35243/batch2-80-05-7-en.pdf
    • (2012) Environment Canada 2008
  • 6
    • 84881171319 scopus 로고    scopus 로고
    • EU directive 2011/8/EU. Commission directive 2011/8/EU of 28 January 2011. [displayed 3 June]
    • EU directive 2011/8/EU. Commission directive 2011/8/EU of 28 January 2011. [displayed 3 June 2011]. Available at http://eur-lex.europa.eu/LexUriServ/ LexUriServ.do?uri=OJ: L:2011:026:0011:0014:EN:PDF
    • (2011)
  • 7
    • 0036176234 scopus 로고    scopus 로고
    • Acute toxicity, mutagenicity, and estrogenicity of bisphenol-A and other bisphenols
    • doi: 10.1002/tox.10035
    • Chen MY, Ike M, Fujita M. Acute toxicity, mutagenicity, and estrogenicity of bisphenol-A and other bisphenols. Environ Toxicol 2002;17:80-6. doi: 10.1002/tox.10035
    • (2002) Environ Toxicol , vol.17 , pp. 80-86
    • Chen, M.Y.1    Ike, M.2    Fujita, M.3
  • 8
    • 10044255258 scopus 로고    scopus 로고
    • Estrogenic activity of alkylphenols, bisphenol S, and their chlorinated derivatives using a GFP expression system
    • doi: 10.1016/j.etap
    • Kuruto-Niwa R, Nozawa R, Miyakoshi T, Shiozawa T, Terao Y. Estrogenic activity of alkylphenols, bisphenol S, and their chlorinated derivatives using a GFP expression system. Environ Toxicol Pharmacol 2005;19:121-30. doi: 10.1016/j.etap
    • (2005) Environ Toxicol Pharmacol , vol.19 , pp. 121-130
    • Kuruto-Niwa, R.1    Nozawa, R.2    Miyakoshi, T.3    Shiozawa, T.4    Terao, Y.5
  • 9
    • 80955149115 scopus 로고    scopus 로고
    • Receipts a large-and largely ignored-source of BPA
    • displayed 30 August
    • Raloff J. Receipts a large-and largely ignored-source of BPA. Science News.org. [displayed 30 August 2010]. Available at http://www.sciencenews.org/ view/generic/id/61764/title/Receipts-a-large- %E2 %80 %94-and-largely-ignored- %E2 %80 %94-source-of-BPA
    • (2010) Science News.Org
    • Raloff, J.1
  • 10
    • 67649185604 scopus 로고    scopus 로고
    • Biodegradation of bisphenol A, bisphenol F and bisphenol S in Seawater
    • doi: 10.3390/ijerph6041472
    • Danzl E, Sei K, Soda S, Ike M, Fujita M. Biodegradation of bisphenol A, bisphenol F and bisphenol S in Seawater. Int J Environ Res Public Health 2009;6:1472-84. doi: 10.3390/ijerph6041472
    • (2009) Int J Environ Res Public Health , vol.6 , pp. 1472-1484
    • Danzl, E.1    Sei, K.2    Soda, S.3    Ike, M.4    Fujita, M.5
  • 11
    • 33744468504 scopus 로고    scopus 로고
    • Biodegradation of a variety of bisphenols under aerobic and anaerobic conditions
    • doi: 10.3390/ijerph6041472
    • Ike M, Chen MY, Danzl E, Sei K, Fujita M. Biodegradation of a variety of bisphenols under aerobic and anaerobic conditions. Water Sci Technol 2006;53:153-9. doi: 10.3390/ijerph6041472
    • (2006) Water Sci Technol , vol.53 , pp. 153-159
    • Ike, M.1    Chen, M.Y.2    Danzl, E.3    Sei, K.4    Fujita, M.5
  • 12
    • 84881133247 scopus 로고    scopus 로고
    • US Patent. 1978. 4,098,769 [displayed 8 December]
    • US Patent. 1978. 4,098,769 [displayed 8 December 2011]. Available at http://www.patents.com/us-4098769.html
    • (2011)
  • 13
    • 79751536947 scopus 로고    scopus 로고
    • Poly(butylene terephthalate) modified with ethoxylated bisphenol S with increased glass transition temperature and improved thermal stability
    • doi: 10.1016/j.polymer.2011.01.018
    • Lotti N, Colonna M, Fiorini M, Finelli L, Berti C. Poly(butylene terephthalate) modified with ethoxylated bisphenol S with increased glass transition temperature and improved thermal stability. Polymer 2011;52:904-11. doi: 10.1016/j.polymer.2011.01.018
    • (2011) Polymer , vol.52 , pp. 904-911
    • Lotti, N.1    Colonna, M.2    Fiorini, M.3    Finelli, L.4    Berti, C.5
  • 15
    • 0034106319 scopus 로고    scopus 로고
    • Mammalian cell transformation and aneuploidy induced by five bisphenols
    • doi: 10.1002/(SICI)1097-0215(20000415)86:2
    • Tsutsui T, Tamura Y, Suzuki A, Hirose Y, Kobayashi M, Nishimura H, Metzler M, Barrett JC. Mammalian cell transformation and aneuploidy induced by five bisphenols. Int J Cancer 2000;86:151-4. doi: 10.1002/(SICI)1097- 0215(20000415)86:2<151::AID-IJC1>3.0.CO;2-0
    • (2000) Int J Cancer , vol.86 , pp. 151-154
    • Tsutsui, T.1    Tamura, Y.2    Suzuki, A.3    Hirose, Y.4    Kobayashi, M.5    Nishimura, H.6    Metzler, M.7    Barrett, J.C.8
  • 16
    • 84881190677 scopus 로고    scopus 로고
    • National Toxicology Program (NTP). Chemical Information Profile for Bisphenol AF [CAS No. 1478-61-1], [displayed 30 March]
    • National Toxicology Program (NTP). Chemical Information Profile for Bisphenol AF [CAS No. 1478-61-1], Supporting Nomination for Toxicological Evaluation by the National Toxicology Program [displayed 30 March 2011]. Available at http://ntp.niehs.nih.gov/ntp/htdocs/Chem-Background/ExSumPdf/ BisphenolAF-093008-508.pdf
    • (2011) Supporting Nomination for Toxicological Evaluation by the National Toxicology Program
  • 17
    • 77955552108 scopus 로고    scopus 로고
    • In utero exposure to diethylstilbestrol (DES) or bisphenol-A (BPA) increases EZH2 expression in the mammary gland: An epigenetic mechanism linking endocrine disruptors to breast cancer
    • doi: 10.1007/s12672-010-0015-9
    • Doherty LF, Bromer JG, Zhou Y, Aldad TS, Taylor HS. In utero exposure to diethylstilbestrol (DES) or bisphenol-A (BPA) increases EZH2 expression in the mammary gland: an epigenetic mechanism linking endocrine disruptors to breast cancer. Horm Cancer 2010;1:146-55. doi: 10.1007/s12672-010-0015-9
    • (2010) Horm Cancer , vol.1 , pp. 146-155
    • Doherty, L.F.1    Bromer, J.G.2    Zhou, Y.3    Aldad, T.S.4    Taylor, H.S.5
  • 18
    • 69949103719 scopus 로고
    • International Agency for Research on Cancer (IARC). International Agency for Research on Cancer, Sex Hormones (II). Lyon: IARC
    • International Agency for Research on Cancer (IARC). International Agency for Research on Cancer, Sex Hormones (II). IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Vol. 21. Lyon: IARC; 1979.
    • (1979) IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans , vol.21
  • 19
    • 84881129468 scopus 로고    scopus 로고
    • Chem Bio3D Ultra 13.0 [Computer software] Perkin Elmer, Release Date: August
    • Chem Bio3D Ultra 13.0 [Computer software] in Chem Bio Office R Ultra 13.0, Perkin Elmer, www.cambridgesoft.com/, Release Date: August, 2012.
    • (2012) Chem Bio Office R Ultra 13.0
  • 20
    • 0023856614 scopus 로고
    • Chemical-structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the United-States NCI/NTP
    • Ashby J, Tennant RW. Chemical-structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the United-States NCI/NTP. Mutat Res 1988;204:17-115.
    • (1988) Mutat Res , vol.204 , pp. 17-115
    • Ashby, J.1    Tennant, R.W.2
  • 21
    • 0031845719 scopus 로고    scopus 로고
    • The mutagenic activity of unpolymerized resin monomers in Salmonella typhimurium and V79 cells
    • Schweikl H, Schmalz G, Rackebrandt K. The mutagenic activity of unpolymerized resin monomers in Salmonella typhimurium and V79 cells. Mutat Res 1998;415:119-30.
    • (1998) Mutat Res , vol.415 , pp. 119-130
    • Schweikl, H.1    Schmalz, G.2    Rackebrandt, K.3
  • 22
    • 0032545649 scopus 로고    scopus 로고
    • Bisphenol-A induces cellular transformation, aneuploidy and DNA adduct formation in cultured Syrian hamster embryo cells
    • doi: 10.1002/(SICI)1097-0215(19980119)75:2
    • Tsutsui T, Tamura Y, Yagi E, Hasegawa K, Takahashi M, Maizumi N, Yamaguchi F, Barrett JC. Bisphenol-A induces cellular transformation, aneuploidy and DNA adduct formation in cultured Syrian hamster embryo cells. Int J Cancer 1998;75:290-4. doi: 10.1002/(SICI)1097-0215(19980119)75:2<290::AID- IJC19>3.0.CO;2-H
    • (1998) Int J Cancer , vol.75 , pp. 290-294
    • Tsutsui, T.1    Tamura, Y.2    Yagi, E.3    Hasegawa, K.4    Takahashi, M.5    Maizumi, N.6    Yamaguchi, F.7    Barrett, J.C.8
  • 23
    • 0024435027 scopus 로고
    • Chromosomal aberrations and sister chromatid exchange tests in Chinese hamster ovary cells in vitro. IV. Results with 15 chemicals
    • doi: 10.1002/em.2850140306
    • Ivett JL, Brown BM, Rodgers C, Anderson BE, Resnick MA, Zeiger E. Chromosomal aberrations and sister chromatid exchange tests in Chinese hamster ovary cells in vitro. IV. Results with 15 chemicals. Environ Mol Mutagen 1989;14:165-87. doi: 10.1002/em.2850140306
    • (1989) Environ Mol Mutagen , vol.14 , pp. 165-187
    • Ivett, J.L.1    Brown, B.M.2    Rodgers, C.3    Anderson, B.E.4    Resnick, M.A.5    Zeiger, E.6
  • 24
    • 67349231920 scopus 로고    scopus 로고
    • Cytogenetic evaluation for genotoxicity of Bisphenol-A in bone marrow cells of Swiss albino mice
    • doi: 10.1016/j.mrgentox.2009.04.010
    • Naik P, Vijayaaxmi KK. Cytogenetic evaluation for genotoxicity of Bisphenol-A in bone marrow cells of Swiss albino mice. Mutat Res 2009;676:106-12. doi: 10.1016/j.mrgentox.2009.04.010
    • (2009) Mutat Res , vol.676 , pp. 106-112
    • Naik, P.1    Vijayaaxmi, K.K.2
  • 25
    • 0029005176 scopus 로고
    • In vitro conversion of environmental estrogenic chemical bisphenol A to DNA binding metabolite(s)
    • Atkinson A, Roy D. In vitro conversion of environmental estrogenic chemical bisphenol A to DNA binding metabolite(s). Biochem Biophys Res Commun 1995;210:424-33.
    • (1995) Biochem Biophys Res Commun , vol.210 , pp. 424-433
    • Atkinson, A.1    Roy, D.2
  • 27
    • 0029088293 scopus 로고
    • In vivo DNA adduct formation by bisphenol A
    • doi: 10.1002/em.2850260109
    • Atkinson A, Roy D. In vivo DNA adduct formation by bisphenol A. Environ Mol Mutagen 1995;26:60-6. doi: 10.1002/em.2850260109
    • (1995) Environ Mol Mutagen , vol.26 , pp. 60-66
    • Atkinson, A.1    Roy, D.2
  • 28
    • 70249150993 scopus 로고    scopus 로고
    • Formation of adducts by bisphenol A, an endocrine disruptor, in DNA in vitro and in liver and mammary tissue of mice
    • doi: 10.1016/j. mrgentox.2009.07.011
    • Izzotti A, Kanitz S, D'Agostini F, Camoirano A, De Flora S. Formation of adducts by bisphenol A, an endocrine disruptor, in DNA in vitro and in liver and mammary tissue of mice. Mutat Res 2009;679:28-32. doi: 10.1016/j. mrgentox.2009.07.011
    • (2009) Mutat Res , vol.679 , pp. 28-32
    • Izzotti, A.1    Kanitz, S.2    D'Agostini, F.3    Camoirano, A.4    De Flora, S.5
  • 29
    • 32044439601 scopus 로고    scopus 로고
    • DNA damage caused by bisphenol A and estradiol through estrogenic activity
    • doi:10.1248/bpb.29.206
    • Iso T, Watanabe T, Iwamoto T, Shimamoto A, Furuichi Y. DNA damage caused by bisphenol A and estradiol through estrogenic activity. Biol Pharm Bull 2006;29:206-10. doi:10.1248/bpb.29.206
    • (2006) Biol Pharm Bull , vol.29 , pp. 206-210
    • Iso, T.1    Watanabe, T.2    Iwamoto, T.3    Shimamoto, A.4    Furuichi, Y.5
  • 30
    • 57449104315 scopus 로고    scopus 로고
    • Genotoxic and endocrine activities of bis(hydroxyphenyl)methane (bisphenol F) and its derivatives in the Hep G2 cell line
    • doi: 10.1016/j.tox.2008.09.024
    • Cabaton N, Dumont C, Severin I, Perdu E, Zalko D, Cherkaoui-Malki M, Chagnon MC. Genotoxic and endocrine activities of bis(hydroxyphenyl)methane (bisphenol F) and its derivatives in the Hep G2 cell line. Toxicology 2009;255:15-24. doi: 10.1016/j.tox.2008.09.024
    • (2009) Toxicology , vol.255 , pp. 15-24
    • Cabaton, N.1    Dumont, C.2    Severin, I.3    Perdu, E.4    Zalko, D.5    Cherkaoui-Malki, M.6    Chagnon, M.C.7
  • 31
    • 80755153618 scopus 로고    scopus 로고
    • Use of the gamma H2AX assay for assessing the genotoxicity of bisphenol A and bisphenol F in human cell lines
    • doi: 10.1007/s00204-011-0721-2
    • Audebert M, Dolo L, Perdu E, Cravedi JP, Zalko D. Use of the gamma H2AX assay for assessing the genotoxicity of bisphenol A and bisphenol F in human cell lines. Arch Toxicol 2011;85:1463-73. doi: 10.1007/s00204-011-0721-2
    • (2011) Arch Toxicol , vol.85 , pp. 1463-1473
    • Audebert, M.1    Dolo, L.2    Perdu, E.3    Cravedi, J.P.4    Zalko, D.5
  • 32
    • 0030906288 scopus 로고    scopus 로고
    • Interference with microtubules and induction of micronuclei in vitro by various bisphenols
    • Pfeiffer E, Rosenberg B, Deuschel S, Metzler M. Interference with microtubules and induction of micronuclei in vitro by various bisphenols. Mutat Res 1997;390:21-31.
    • (1997) Mutat Res , vol.390 , pp. 21-31
    • Pfeiffer, E.1    Rosenberg, B.2    Deuschel, S.3    Metzler, M.4
  • 33
    • 0035399607 scopus 로고    scopus 로고
    • Cell-transforming activity and estrogenicity of bisphenol-A and 4 of its analogs in mammalian cells
    • doi: 10.1002/ijc.1303
    • Kanai H, Barrett JC, Metzler M, Tsutsui T. Cell-transforming activity and estrogenicity of bisphenol-A and 4 of its analogs in mammalian cells. Int J Cancer 2001;93:20-5. doi: 10.1002/ijc.1303
    • (2001) Int J Cancer , vol.93 , pp. 20-25
    • Kanai, H.1    Barrett, J.C.2    Metzler, M.3    Tsutsui, T.4
  • 34
    • 0020533372 scopus 로고
    • Revised methods for the Salmonella mutagenicity test
    • Maron DM, Ames BN. Revised methods for the Salmonella mutagenicity test. Mutat Res 1983;113:173-215.
    • (1983) Mutat Res , vol.113 , pp. 173-215
    • Maron, D.M.1    Ames, B.N.2
  • 35
    • 34249088320 scopus 로고    scopus 로고
    • An evaluation of the sensitivity of the Ames assay to discern low-level mutagenic impurities
    • doi: 10.1016/j.yrtph.2007.01.006
    • Kenyon MO, Cheung JR, Dobo KL, Ku WW. An evaluation of the sensitivity of the Ames assay to discern low-level mutagenic impurities. Regul Toxicol Pharmacol 2007;48:75-86. doi: 10.1016/j.yrtph.2007.01.006
    • (2007) Regul Toxicol Pharmacol , vol.48 , pp. 75-86
    • Kenyon, M.O.1    Cheung, J.R.2    Dobo, K.L.3    Ku, W.W.4
  • 36
    • 36148949386 scopus 로고    scopus 로고
    • Phase II enzyme levels in Hep G2 cells and cryopreserved primary human hepatocytes and their induction in Hep G2 cells
    • doi: 10.1016/j.tiv.2007.06.017
    • Westerink WM, Schoonen WG. Phase II enzyme levels in Hep G2 cells and cryopreserved primary human hepatocytes and their induction in Hep G2 cells. Toxicol In Vitro 2007;21:1592-602. doi: 10.1016/j.tiv.2007.06.017
    • (2007) Toxicol in Vitro , vol.21 , pp. 1592-1602
    • Westerink, W.M.1    Schoonen, W.G.2
  • 37
    • 36148955117 scopus 로고    scopus 로고
    • Cytochrome P450 enzyme levels in Hep G2 cells and cryopreserved primary human hepatocytes and their induction in Hep G2 cells
    • doi: 10.1016/j.tiv.2007.05.014
    • Westerink WM, Schoonen WG. Cytochrome P450 enzyme levels in Hep G2 cells and cryopreserved primary human hepatocytes and their induction in Hep G2 cells. Toxicol In Vitro 2007;21:1581-91. doi: 10.1016/j.tiv.2007.05.014
    • (2007) Toxicol in Vitro , vol.21 , pp. 1581-1591
    • Westerink, W.M.1    Schoonen, W.G.2
  • 38
    • 0042904900 scopus 로고    scopus 로고
    • Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties
    • doi: 10.1124/dmd.31.8.1035
    • Wilkening S, Stahl F, Bader A. Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties. Drug Metab Dispos 2003;31:1035-42. doi: 10.1124/dmd.31.8.1035
    • (2003) Drug Metab Dispos , vol.31 , pp. 1035-1042
    • Wilkening, S.1    Stahl, F.2    Bader, A.3
  • 39
    • 70350277981 scopus 로고    scopus 로고
    • Organophosphorus pesticides enhance the genotoxicity of benzo(a)pyrene by modulating its metabolism
    • doi: 10.1016/j. mrfmmm.2009.09.011
    • Hreljac I, Filipič M. Organophosphorus pesticides enhance the genotoxicity of benzo(a)pyrene by modulating its metabolism. Mutat Res 2009;671:84-92. doi: 10.1016/j. mrfmmm.2009.09.011
    • (2009) Mutat Res , vol.671 , pp. 84-92
    • Hreljac, I.1    Filipič, M.2
  • 41
    • 24944498888 scopus 로고    scopus 로고
    • Differential subcellular distribution of estrogen receptor isoforms: Localization of ERα in the nucleoli and ERβ in the mitochondria of human osteosarcoma SaOS-2 and hepatocarcinoma HepG2 cell lines
    • doi: 10.1016/j.bbamcr.2005.05.010
    • Solakidi S, Psarra AMG, Sekeris CE. Differential subcellular distribution of estrogen receptor isoforms: Localization of ERα in the nucleoli and ERβ in the mitochondria of human osteosarcoma SaOS-2 and hepatocarcinoma Hep G2 cell lines. Biochim Biophys Acta-Mol Cell Res 2005;1745:382-92. doi: 10.1016/j.bbamcr.2005.05.010
    • (2005) Biochim Biophys Acta-Mol Cell Res , vol.1745 , pp. 382-392
    • Solakidi, S.1    Psarra, A.M.G.2    Sekeris, C.E.3
  • 42
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • doi: 10.1016/0022-1759(83)90303-4
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Meth 1983;65:55-63. doi: 10.1016/0022-1759(83)90303-4
    • (1983) J Immunol Meth , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 43
    • 40249098704 scopus 로고    scopus 로고
    • Patterns of microcystin-LR induced alteration of the expression of genes involved in response to DNA damage and apoptosis
    • doi: 10.1016/j.toxicon.2007.11.009
    • Žegura B, Zajc I, Lah TT, Filipič M. Patterns of microcystin-LR induced alteration of the expression of genes involved in response to DNA damage and apoptosis. Toxicon 2008;51:615-23. doi: 10.1016/j.toxicon.2007.11.009
    • (2008) Toxicon , vol.51 , pp. 615-623
    • Žegura, B.1    Zajc, I.2    Lah, T.T.3    Filipič, M.4
  • 44
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh NP, McCoy MT, Tice RR, Schneider EL. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 1988;175:184-91.
    • (1988) Exp Cell Res , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 45
    • 38949139320 scopus 로고    scopus 로고
    • Application of in vitro comet assay for genotoxicity testing
    • In: Yan Z, Caldwell G, editors.: In vitro methods. Totowa (NJ): Humana Press
    • Žegura B, Filipič M. Application of in vitro comet assay for genotoxicity testing. In: Yan Z, Caldwell G, editors. Optimization in drug discovery: In vitro methods. Totowa (NJ): Humana Press; 2004. p. 301-13.
    • (2004) Optimization in Drug Discovery , pp. 301-313
    • Žegura, B.1    Filipič, M.2
  • 46
    • 84857457831 scopus 로고    scopus 로고
    • Clastogenic and mutagenic effects of bisphenol A: An endocrine disruptor
    • doi: doi: 10.1016/j. mrgentox.2011.12.023
    • Tiwari D, Kamble J, Chilgunde S, Patil P, Maru G, Kawle D, Bhartiya U, Joseph L, Vanage G. Clastogenic and mutagenic effects of bisphenol A: an endocrine disruptor. Mutat Res 2012;743:83-90. doi: doi: 10.1016/j. mrgentox.2011.12.023
    • (2012) Mutat Res , vol.743 , pp. 83-90
    • Tiwari, D.1    Kamble, J.2    Chilgunde, S.3    Patil, P.4    Maru, G.5    Kawle, D.6    Bhartiya, U.7    Joseph, L.8    Vanage, G.9
  • 49
    • 84881155615 scopus 로고    scopus 로고
    • National toxicology program. 2001
    • National Institute of Environmental Health Sciences (NIH). [displayed 20 Dec]
    • National Institute of Environmental Health Sciences (NIH). National Toxicology Program. 2001. National Toxicology Program's Report of the Endocrine Disruptors Low-Dose Peer Review [displayed 20 Dec 2011]. Available at www.epa.gov/endo/pubs/edmvs/lowdosepeerfinalrpt.pdf
    • (2011) National Toxicology Program's Report of the Endocrine Disruptors Low-Dose Peer Review
  • 53
    • 33846980785 scopus 로고    scopus 로고
    • Modulation of the expression of Bloom helicase by estrogenic agents
    • doi: 10.1248/bpb.30.266
    • Iso T, Futami K, Iwamoto T, Furuichi Y. Modulation of the expression of Bloom helicase by estrogenic agents. Biol Pharm Bull 2007;30:266-71. doi: 10.1248/bpb.30.266
    • (2007) Biol Pharm Bull , vol.30 , pp. 266-271
    • Iso, T.1    Futami, K.2    Iwamoto, T.3    Furuichi, Y.4
  • 54
    • 79951989428 scopus 로고    scopus 로고
    • Is bisphenol a a weak carcinogen like the natural estrogens and diethylstilbestrol?
    • doi: 10.1002/iub.376
    • Cavalieri EL, Rogan EG. Is Bisphenol A a weak carcinogen like the natural estrogens and diethylstilbestrol? IUBMB Life 2010;62:746-51. doi: 10.1002/iub.376
    • (2010) IUBMB Life , vol.62 , pp. 746-751
    • Cavalieri, E.L.1    Rogan, E.G.2
  • 55
    • 84875597848 scopus 로고    scopus 로고
    • Bioactivation of bisphenol A and its analogs (BPF, BPAF, BPZ and DMBPA) in human liver microsomes
    • doi: 10.1016/j.tiv.2013.02.016
    • Schmidt J, Kotnik P, Trontelj J, Knez Z, Mašič LP. Bioactivation of bisphenol A and its analogs (BPF, BPAF, BPZ and DMBPA) in human liver microsomes. Toxicol In Vitro 2013;27:1267-76. doi: 10.1016/j.tiv.2013.02. 016
    • (2013) Toxicol in Vitro , vol.27 , pp. 1267-1276
    • Schmidt, J.1    Kotnik, P.2    Trontelj, J.3    Knez, Z.4    Mašič, L.P.5
  • 56
    • 3242810352 scopus 로고    scopus 로고
    • Characterization of new bisphenol a metabolites produced by CD1 mice liver microsomes and S9 fractions
    • doi: 10.1021/jf049762u
    • Jaeg JP, Perdu E, Dolo L, Debrauwer L, Cravedi JP, Zalko D. Characterization of new bisphenol a metabolites produced by CD1 mice liver microsomes and S9 fractions. J Agric Food Chem 2004;52:4935-42. doi: 10.1021/jf049762u
    • (2004) J Agric Food Chem , vol.52 , pp. 4935-4942
    • Jaeg, J.P.1    Perdu, E.2    Dolo, L.3    Debrauwer, L.4    Cravedi, J.P.5    Zalko, D.6
  • 57
    • 0034938818 scopus 로고    scopus 로고
    • Metabolism of bisphenol A in isolated rat hepatocytes and oestrogenic activity of a hydroxylated metabolite in MCF-7 human breast cancer cells
    • Nakagawa Y, Suzuki T. Metabolism of bisphenol A in isolated rat hepatocytes and oestrogenic activity of a hydroxylated metabolite in MCF-7 human breast cancer cells. Xenobiotica 2001;31:113-23.
    • (2001) Xenobiotica , vol.31 , pp. 113-123
    • Nakagawa, Y.1    Suzuki, T.2
  • 58
    • 84855348205 scopus 로고    scopus 로고
    • Reactivity of bisphenol A-3,4-quinone with DNA. A quantum chemical study
    • doi: 10.1016/j. tiv.2011.11.003
    • Kolšek K, Mavri J, Sollner Dolenc M. Reactivity of bisphenol A-3,4-quinone with DNA. A quantum chemical study. Toxicol in Vitro 2012;26:102-6. doi: 10.1016/j. tiv.2011.11.003
    • (2012) Toxicol in Vitro , vol.26 , pp. 102-106
    • Kolšek, K.1    Mavri, J.2    Sollner Dolenc, M.3
  • 59
    • 77955052231 scopus 로고    scopus 로고
    • Bisphenol A 3,4-quinone induces the conversion of xanthine dehydrogenase into oxidase in vitro
    • doi: 10.1016/j.fct.2010.05.051
    • Sakuma S, Nakanishi M, Morinaga K, Fujitake M, Wada S, Fujimoto Y. Bisphenol A 3,4-quinone induces the conversion of xanthine dehydrogenase into oxidase in vitro. Food Chem Toxicol 2010;48:2217-22. doi: 10.1016/j.fct.2010.05. 051
    • (2010) Food Chem Toxicol , vol.48 , pp. 2217-2222
    • Sakuma, S.1    Nakanishi, M.2    Morinaga, K.3    Fujitake, M.4    Wada, S.5    Fujimoto, Y.6
  • 61
    • 80053026649 scopus 로고    scopus 로고
    • Structural determinant of chemical reactivity and potential health effects of quinones from natural products
    • doi: 10.1021/tx200140s
    • Tu T, Giblin D, Gross ML. Structural determinant of chemical reactivity and potential health effects of quinones from natural products. Chem Res Toxicol 2011;24:1527-39. doi: 10.1021/tx200140s
    • (2011) Chem Res Toxicol , vol.24 , pp. 1527-1539
    • Tu, T.1    Giblin, D.2    Gross, M.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.