-
1
-
-
84881132885
-
-
Clinical Applications 1st edn., (CRC Press, Taylor & Francis, Boca Raton, FL
-
Kawakami, K., Aggarwal, B.B. & Puri, R.K. Cytotoxins and Immunotoxins for Cancer Therapy: Clinical Applications 1st edn., (CRC Press, Taylor & Francis, Boca Raton, FL, 2004).
-
(2004)
Cytotoxins and Immunotoxins for Cancer Therapy
-
-
Kawakami, K.1
Aggarwal, B.B.2
Puri, R.K.3
-
2
-
-
33846471662
-
Denileukin diftitox: A biotherapeutic paradigm shift in the treatment of lymphoid-derived disorders
-
DOI 10.1586/14737140.7.1.11
-
Turturro, F. Denileukin diftitox: a biotherapeutic paradigm shift in the treatment of lymphoidderived disorders. Expert Rev. Anticancer Ther. 7, 11-17 (2007). (Pubitemid 46157644)
-
(2007)
Expert Review of Anticancer Therapy
, vol.7
, Issue.1
, pp. 11-17
-
-
Turturro, F.1
-
3
-
-
0034001076
-
Phase I trial of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignancies
-
Kreitman, R.J. et al. Phase I trial of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignancies. J. Clin. Oncol. 18, 1622-1636 (2000). (Pubitemid 30220540)
-
(2000)
Journal of Clinical Oncology
, vol.18
, Issue.8
, pp. 1622-1636
-
-
Kreitman, R.J.1
Wilson, W.H.2
White, J.D.3
Stetler-Stevenson, M.4
Jaffe, E.S.5
Giardina, S.6
Waldmann, T.A.7
Pastan, I.8
-
4
-
-
27244448693
-
Phase I trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with B-cell malignancies
-
DOI 10.1200/JCO.2005.11.437
-
Kreitman, R.J. et al. Phase I trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with B-cell malignancies. J. Clin. Oncol. 23, 6719-6729 (2005). (Pubitemid 46190267)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.27
, pp. 6719-6729
-
-
Kreitman, R.J.1
Squires, D.R.2
Stetler-Stevenson, M.3
Noel, P.4
FitzGerald, D.J.P.5
Wilson, W.H.6
Pastan, I.7
-
5
-
-
33745363524
-
Convection-enhanced delivery of interleukin-13 receptor-directed cytotoxin for malignant glioma therapy
-
Kioi, M., Husain, S.R., Croteau, D., Kunwar, S. & Puri, R.K. Convection-enhanced delivery of interleukin-13 receptor-directed cytotoxin for malignant glioma therapy. Technol. Cancer Res. Treat. 5, 239-250 (2006). (Pubitemid 43946257)
-
(2006)
Technology in Cancer Research and Treatment
, vol.5
, Issue.3
, pp. 239-250
-
-
Kioi, M.1
Husain, S.R.2
Croteau, D.3
Kunwar, S.4
Puri, R.K.5
-
6
-
-
77949762340
-
Targeting of drugs and nanoparticles to tumors
-
Ruoslahti, E., Bhatia, S.N. & Sailor, M.J. Targeting of drugs and nanoparticles to tumors. J. Cell Biol. 188, 759-768 (2010).
-
(2010)
J. Cell Biol.
, vol.188
, pp. 759-768
-
-
Ruoslahti, E.1
Bhatia, S.N.2
Sailor, M.J.3
-
7
-
-
15444364588
-
Simultaneous inhibition of Epidermal Growth Factor Receptor (EGFR) signaling and enhanced activation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor-mediated apoptosis induction by an scFv: STRAIL fusion protein with specificity for human EGFR
-
DOI 10.1074/jbc.M413673200
-
Bremer, E. et al. Simultaneous inhibition of epidermal growth factor receptor (EGFR) signaling and enhanced activation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor-mediated apoptosis induction by an scFv:sTRAIL fusion protein with specificity for human EGFR. J. Biol. Chem. 280, 10025-10033 (2005). (Pubitemid 40395853)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.11
, pp. 10025-10033
-
-
Bremer, E.1
Samplonius, D.F.2
Van Genne, L.3
Dijkstra, M.H.4
Kroesen, B.J.5
De Leij, L.F.M.H.6
Helfrich, W.7
-
8
-
-
17144382484
-
Target cell-restricted apoptosis induction of acute leukemic T cells by a recombinant tumor necrosis factor-related apoptosis-inducing ligand fusion protein with specificity for human CD7
-
Bremer, E. et al. Target cell-restricted apoptosis induction of acute leukemic T cells by a recombinant tumor necrosis factor-related apoptosis-inducing ligand fusion protein with specificity for human CD7. Cancer Res. 65, 3380-3388 (2005). (Pubitemid 40524623)
-
(2005)
Cancer Research
, vol.65
, Issue.8
, pp. 3380-3388
-
-
Bremer, E.1
Samplonius, D.F.2
Peipp, M.3
Van Genne, L.4
Kroesen, B.-J.5
Fey, G.H.6
Gramatzki, M.7
De Leij, L.F.M.H.8
Helfrich, W.9
-
9
-
-
36348971707
-
Selective induction of apoptosis in leukemic B-lymphoid cells by a CD19-specific TRAIL fusion protein
-
DOI 10.1007/s00262-007-0370-8
-
Stieglmaier, J. et al. Selective induction of apoptosis in leukemic B-lymphoid cells by a CD19-specific TRAIL fusion protein. Cancer Immunol. Immunother. 57, 233-246 (2008). (Pubitemid 350159925)
-
(2008)
Cancer Immunology, Immunotherapy
, vol.57
, Issue.2
, pp. 233-246
-
-
Stieglmaier, J.1
Bremer, E.2
Kellner, C.3
Liebig, T.M.4
Ten Cate, B.5
Peipp, M.6
Schulze-Koops, H.7
Pfeiffer, M.8
Buhring, H.-J.9
Greil, J.10
Oduncu, F.11
Emmerich, B.12
Fey, G.H.13
Helfrich, W.14
-
10
-
-
33645509276
-
CD7-restricted activation of Fas-mediated apoptosis: A novel therapeutic approach for acute T-cell leukemia
-
Bremer, E., ten Cate, B., Samplonius, D.F., de Leij, L.F. & Helfrich, W. CD7-restricted activation of Fas-mediated apoptosis: a novel therapeutic approach for acute T-cell leukemia. Blood 107, 2863-2870 (2006).
-
(2006)
Blood
, vol.107
, pp. 2863-2870
-
-
Bremer, E.1
Ten Cate, B.2
Samplonius, D.F.3
De Leij, L.F.4
Helfrich, W.5
-
11
-
-
39049144862
-
Superior activity of fusion protein scFvRit: SFasL over cotreatment with rituximab and fas agonists
-
DOI 10.1158/0008-5472.CAN-07-5171
-
Bremer, E. et al. Superior activity of fusion protein scFvRit:sFasL over cotreatment with rituximab and Fas agonists. Cancer Res. 68, 597-604 (2008). (Pubitemid 351380089)
-
(2008)
Cancer Research
, vol.68
, Issue.2
, pp. 597-604
-
-
Bremer, E.1
Ten Cate, B.2
Samplonius, D.F.3
Mueller, N.4
Wajant, H.5
Stel, A.J.6
Chamuleau, M.7
Van De Loosdrecht, A.A.8
Stieglmaier, J.9
Fey, G.H.10
Helfrich, W.11
-
12
-
-
77951019547
-
Targeted delivery of interferonalpha via fusion to anti-CD20 results in potent antitumor activity against B-cell lymphoma
-
Xuan, C., Steward, K.K., Timmerman, J.M. & Morrison, S.L. Targeted delivery of interferonalpha via fusion to anti-CD20 results in potent antitumor activity against B-cell lymphoma. Blood 115, 2864-2871 (2010).
-
(2010)
Blood
, vol.115
, pp. 2864-2871
-
-
Xuan, C.1
Steward, K.K.2
Timmerman, J.M.3
Morrison, S.L.4
-
13
-
-
79955986954
-
Anti-tumor efficacy and pre-clinical immunogenicity of IFNa2a-NGR
-
Zhang, B., Gao, B., Dong, S., Zhang, Y. & Wu, Y. Anti-tumor efficacy and pre-clinical immunogenicity of IFNa2a-NGR. Regul. Toxicol. Pharmacol. 60, 73-78 (2011).
-
(2011)
Regul. Toxicol. Pharmacol.
, vol.60
, pp. 73-78
-
-
Zhang, B.1
Gao, B.2
Dong, S.3
Zhang, Y.4
Wu, Y.5
-
14
-
-
43749102294
-
Enhancement of cell type specificity by quantitative modulation of a chimeric ligand
-
Cironi, P., Swinburne, I.A. & Silver, P.A. Enhancement of cell type specificity by quantitative modulation of a chimeric ligand. J. Biol. Chem. 283, 8469-8476 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 8469-8476
-
-
Cironi, P.1
Swinburne, I.A.2
Silver, P.A.3
-
15
-
-
0022742588
-
Transcriptional regulation of interferon-responsive genes is closely linked to interferon receptor occupancy
-
Hannigan, G. & Williams, B.R. Transcriptional regulation of interferon-responsive genes is closely linked to interferon receptor occupancy. EMBO J. 5, 1607-1613 (1986).
-
(1986)
EMBO J.
, vol.5
, pp. 1607-1613
-
-
Hannigan, G.1
Williams, B.R.2
-
16
-
-
79952635820
-
Measuring and modeling apoptosis in single cells
-
Spencer, S.L. & Sorger, P.K. Measuring and modeling apoptosis in single cells. Cell 144, 926-939 (2011).
-
(2011)
Cell
, vol.144
, pp. 926-939
-
-
Spencer, S.L.1
Sorger, P.K.2
-
17
-
-
63649163700
-
How accurate are polymer models in the analysis of Förster resonance energy transfer experiments on proteins
-
O'Brien, E.P., Morrison, G., Brooks, B.R. & Thirumalai, D. How accurate are polymer models in the analysis of Förster resonance energy transfer experiments on proteins? J. Chem. Phys. 130, 124903 (2009).
-
(2009)
J. Chem. Phys.
, vol.130
, pp. 124903
-
-
O'Brien, E.P.1
Morrison, G.2
Brooks, B.R.3
Thirumalai, D.4
-
18
-
-
0023156382
-
Self-phosphorylation of epidermal growth factor receptor: Evidence for a model of intermolecular allosteric activation
-
DOI 10.1021/bi00379a034
-
Yarden, Y. & Schlessinger, J. Self-phosphorylation of epidermal growth factor receptor: evidence for a model of intermolecular allosteric activation. Biochemistry 26, 1434-1442 (1987). (Pubitemid 17045874)
-
(1987)
Biochemistry
, vol.26
, Issue.5
, pp. 1434-1442
-
-
Yarden, Y.1
Schlessinger, J.2
-
19
-
-
84881134643
-
-
ed. Nicola, N.A.), (Oxford UniversityPress, Oxford; New York; Tokyo
-
Uze, G., Lutfalla, G. & Mogensen, K.E. In Guidebook to Cytokines and Their Receptors (ed. Nicola, N.A.), 115-118 (Oxford UniversityPress, Oxford; New York; Tokyo, 1994).
-
(1994)
Guidebook to Cytokines and Their Receptors
, pp. 115-118
-
-
Uze, G.1
Lutfalla, G.2
Mogensen, K.E.3
-
20
-
-
0032836086
-
Interferon-α induces apoptosis in human KB cells through a stress-dependent mitogen activated protein kinase pathway that is antagonized by epidermal growth factor
-
Caraglia, M. et al. Interferon-alpha induces apoptosis in human KB cells through a stressdependent mitogen activated protein kinase pathway that is antagonized by epidermal growth factor. Cell Death Differ. 6, 773-780 (1999). (Pubitemid 29425388)
-
(1999)
Cell Death and Differentiation
, vol.6
, Issue.8
, pp. 773-780
-
-
Caraglia, M.1
Abbruzzese, A.2
Leardi, A.3
Pepe, S.4
Budillon, A.5
Baldassare, G.6
Selleri, C.7
De Lorenzo, S.8
Fabbrocini, A.9
Giuberti, G.10
Vitale, G.11
Lupoli, G.12
Bianco, A.R.13
Tagliaferri, P.14
-
21
-
-
0003519552
-
-
Oxford University Press, Huntington Beach, CA
-
Lauffenburger, D.A. & Linderman, J. Receptors: Models for Binding, Trafficking, and Signaling 130-180 (Oxford University Press, Huntington Beach, CA, 1996).
-
(1996)
Models for Binding, Trafficking, and Signaling
, pp. 130-180
-
-
Lauffenburger, D.A.1
Receptors, L.J.2
-
22
-
-
0040806918
-
-
Freeman, San Francisco, CA
-
Adam, G. & Delbruck, M. Structural Chemistry in Molecular Biology 198-215 (Freeman, San Francisco, CA, 1968).
-
(1968)
Structural Chemistry in Molecular Biology
, pp. 198-215
-
-
Adam, G.1
Delbruck, M.2
-
23
-
-
40449112970
-
Intracellular water-specific MR of microbead-adherent cells: The HeLa cell intracellular water exchange lifetime
-
DOI 10.1002/nbm.1173
-
Zhao, L., Kroenke, C.D., Song, J., Piwnica-Worms, D., Ackerman, J.J. & Neil, J.J. Intracellular water-specific MR of microbead-adherent cells: the HeLa cell intracellular water exchange lifetime. NMR Biomed. 21, 159-164 (2008). (Pubitemid 351351008)
-
(2008)
NMR in Biomedicine
, vol.21
, Issue.2
, pp. 159-164
-
-
Zhao, L.1
Kroenke, C.D.2
Song, J.3
Piwnica-Worms, D.4
Ackerman, J.J.H.5
Neil, J.J.6
-
24
-
-
34347355576
-
Cell surface receptors for signal transduction and ligand transport: A design principles study
-
Shankaran, H., Resat, H. & Wiley, H.S. Cell surface receptors for signal transduction and ligand transport: a design principles study. PLoS Comput. Biol. 3, e101 (2007).
-
(2007)
PLoS Comput. Biol.
, vol.3
-
-
Shankaran, H.1
Resat, H.2
Wiley, H.S.3
-
25
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell, J.E. Jr, Kerr, I.M. & Stark, G.R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264, 1415-1421 (1994). (Pubitemid 24217131)
-
(1994)
Science
, vol.264
, Issue.5164
, pp. 1415-1421
-
-
Darnell Jr., J.E.1
Kerr, I.M.2
Stark, G.R.3
-
26
-
-
0023159806
-
Interferons and their actions
-
Pestka, S., Langer, J.A., Zoon, K.C. & Samuel, C.E. Interferons and their actions. Annu. Rev. Biochem. 56, 727-777 (1987). (Pubitemid 17105465)
-
(1987)
Annual Review of Biochemistry
, vol.56
, pp. 727-777
-
-
Pestka, S.1
Langer, J.A.2
Zoon, K.C.3
Samuel, C.E.4
-
27
-
-
0035884231
-
The epidermal growth factor receptor: From mutant oncogene in nonhuman cancers to therapeutic target in human neoplasia
-
Arteaga, C.L. The epidermal growth factor receptor: from mutant oncogene in nonhuman cancers to therapeutic target in human neoplasia. J. Clin. Oncol. 19, 32S-40S (2001). (Pubitemid 32880077)
-
(2001)
Journal of Clinical Oncology
, vol.19
, Issue.18 SUPPL.
-
-
Arteaga, C.L.1
-
28
-
-
0025012540
-
2a and tumor necrosis factor-α by human tumor cells
-
Dunne, S.L., Bajzer, Z. & Vuk-Pavlovic, S. Kinetics of receptor-mediated uptake and processing of interferon-alpha 2a and tumor necrosis factor-alpha by human tumor cells. Growth Factors 2, 167-177 (1990). (Pubitemid 20057754)
-
(1990)
Growth Factors
, vol.2
, Issue.2-3
, pp. 167-177
-
-
Dunne, S.L.1
Bajzer, Z.2
Vuk-Pavlovic, S.3
-
29
-
-
0034704093
-
New structural and functional aspects of the type I interferon-receptor interaction revealed by comprehensive mutational analysis of the binding interface
-
DOI 10.1074/jbc.M006854200
-
Piehler, J., Roisman, L.C. & Schreiber, G. New structural and functional aspects of the type I interferon-receptor interaction revealed by comprehensive mutational analysis of the binding interface. J. Biol. Chem. 275, 40425-40433 (2000). (Pubitemid 32064677)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.51
, pp. 40425-40433
-
-
Piehler, J.1
Roisman, L.C.2
Schreiber, G.3
-
30
-
-
14044276994
-
Parsing ERK activation reveals quantitatively equivalent contributions from epidermal growth factor receptor and HER2 in human mammary epithelial cells
-
DOI 10.1074/jbc.M410491200
-
Hendriks, B.S., Orr, G., Wells, A., Wiley, H.S. & Lauffenburger, D.A. Parsing ERK activation reveals quantitatively equivalent contributions from epidermal growth factor receptor and HER2 in human mammary epithelial cells. J. Biol. Chem. 280, 6157-6169 (2005). (Pubitemid 40280101)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.7
, pp. 6157-6169
-
-
Hendriks, B.S.1
Orr, G.2
Wells, A.3
Wiley, H.S.4
Lauffenburger, D.A.5
-
31
-
-
0041843750
-
An integrated model of epidermal growth factor receptor trafficking and signal transduction
-
Resat, H., Ewald, J.A., Dixon, D.A. & Wiley, H.S. An integrated model of epidermal growth factor receptor trafficking and signal transduction. Biophys. J. 85, 730-743 (2003). (Pubitemid 36909642)
-
(2003)
Biophysical Journal
, vol.85
, Issue.2
, pp. 730-743
-
-
Resat, H.1
Ewald, J.A.2
Dixon, D.A.3
Wiley, H.S.4
-
32
-
-
18644386251
-
Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains
-
DOI 10.1016/S0092-8674(02)00963-7
-
Ogiso, H. et al. Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains. Cell 110, 775-787 (2002). (Pubitemid 35291060)
-
(2002)
Cell
, vol.110
, Issue.6
, pp. 775-787
-
-
Ogiso, H.1
Ishitani, R.2
Nureki, O.3
Fukai, S.4
Yamanaka, M.5
Kim, J.-H.6
Saito, K.7
Sakamoto, A.8
Inoue, M.9
Shirouzu, M.10
Yokoyama, S.11
-
33
-
-
18644370411
-
Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor α
-
DOI 10.1016/S0092-8674(02)00940-6
-
Garrett, T.P. et al. Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha. Cell 110, 763-773 (2002). (Pubitemid 35283965)
-
(2002)
Cell
, vol.110
, Issue.6
, pp. 763-773
-
-
Garrett, T.P.J.1
McKern, N.M.2
Lou, M.3
Elleman, T.C.4
Adams, T.E.5
Lovrecz, G.O.6
Zhu, H.-J.7
Walker, F.8
Frenkel, M.J.9
Hoyne, P.A.10
Jorissen, R.N.11
Nice, E.C.12
Burgess, A.W.13
Ward, C.W.14
-
34
-
-
40849135547
-
Single-molecule diffusion study of activated EGFR implicates its endocytic pathway
-
Xiao, Z., Zhang, W., Yang, Y., Xu, L. & Fang, X. Single-molecule diffusion study of activated EGFR implicates its endocytic pathway. Biochem. Biophys. Res. Commun. 369, 730-734 (2008).
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.369
, pp. 730-734
-
-
Xiao, Z.1
Zhang, W.2
Yang, Y.3
Xu, L.4
Fang, X.5
-
35
-
-
0035818558
-
Structure of the interferon-receptor complex determined by distance constraints from double-mutant cycles and flexible docking
-
DOI 10.1073/pnas.221290398
-
Roisman, L.C., Piehler, J., Trosset, J.Y., Scheraga, H.A. & Schreiber, G. Structure of the interferon-receptor complex determined by distance constraints from double-mutant cycles and flexible docking. Proc. Natl. Acad. Sci. U.S.A. 98, 13231-13236 (2001). (Pubitemid 33051345)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.23
, pp. 13231-13236
-
-
Roisman, L.C.1
Piehler, J.2
Trosset, J.-Y.3
Scheraga, H.A.4
Schreiber, G.5
|