Parsing ERK activation reveals quantitatively equivalent contributions from epidermal growth factor receptor and HER2 in human mammary epithelial cells

Journal of Biological Chemistry

Volumn 280, Issue 7, 2005, Pages 6157-6169

  Hendriks, Bart S ^a   Orr, Gayla ^d   Wells, Alan ^c   Wiley, H Steven ^d   Lauffenburger, Douglas A ^a,b  

^a USA   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CELLS; COMPUTATIONAL METHODS; DIMERIZATION; MATHEMATICAL MODELS; STOICHIOMETRY;

EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR); HETERODIMERIZATION; MOTILITY; PROLIFERATION;

ENZYMES;

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; BREAST EPITHELIUM; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; STOICHIOMETRY;

ANIMALS; CATTLE; CELL LINE; DIMERIZATION; EPIDERMAL GROWTH FACTOR; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; MODELS, BIOLOGICAL; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION;

EID: 14044276994     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M410491200     Document Type: Article

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