The NLRP3 inflammasome affects DNA damage responses after oxidative and genotoxic stress in dendritic cells

European Journal of Immunology

Volumn 43, Issue 8, 2013, Pages 2126-2137

  Licandro, Ginevra ^a   Ling Khor, Hwei ^a   Beretta, Ottavio ^a   Lai, Junyun ^a   Derks, Heidi ^a   Laudisi, Federica ^a   Conforti Andreoni, Cristina ^a   Liang Qian, Hong ^a   Gee Teng, Gim ^b   Ricciardi Castagnoli, Paola ^a   Mortellaro, Alessandra ^a  

^a AGENCY FOR SCIENCE   (Singapore)

^b NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

Author keywords

Apoptosis; DNA damage response; Innate immunity; NLRP3 inflammasome

Indexed keywords

ATM PROTEIN; ATR PROTEIN; CRYOPYRIN; HISTONE H2AX; INFLAMMASOME; NIBRIN; PROTEIN P53; REACTIVE OXYGEN METABOLITE; ROTENONE; URATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DENDRITIC CELL; DNA DAMAGE; DNA FRAGMENTATION; DNA REPAIR; DOUBLE STRANDED DNA BREAK; EXCISION REPAIR; GAMMA RADIATION; GENE EXPRESSION; GENOTOXICITY; IN VITRO STUDY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS; WILD TYPE;

APOPTOSIS; DNA DAMAGE RESPONSE; INNATE IMMUNITY; NLRP3 INFLAMMASOME;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CARRIER PROTEINS; CASPASE 1; CELL SURVIVAL; CELLS, CULTURED; DENDRITIC CELLS; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVATION; INFLAMMASOMES; INFLAMMATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATIVE STRESS; PERITONITIS; REACTIVE OXYGEN SPECIES; ROTENONE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; UNCOUPLING AGENTS; URIC ACID;

EID: 84881064928     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201242918     Document Type: Article

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