Tat engagement of p38 MAP kinase and IRF7 pathways leads to activation of interferon-stimulated genes in antigen-presenting cells

Blood

Volumn 121, Issue 20, 2013, Pages 4090-4100

  Kim, Nayoung ^a   Kukkonen, Sami ^a,b   Martinez Viedma, Maria Del Pilar ^a,b   Gupta, Sumeet ^c   Aldovini, Anna ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ADENOVIRUS VECTOR; CHEMOKINE; CYTOKINE; INTERFERON REGULATORY FACTOR 7; MITOGEN ACTIVATED PROTEIN KINASE P38; RNA; STAT1 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSACTIVATOR PROTEIN; CHEMOKINE RECEPTOR; INTERFERON; IRF7 PROTEIN, HUMAN; MAP2K3 PROTEIN, HUMAN; MAP2K6 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6;

ANTIGEN PRESENTING CELL; ARTICLE; DENDRITIC CELL; ENZYME INHIBITION; GENE; GENE ACTIVATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MACROPHAGE; MODULATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RNA INTERFERENCE; T LYMPHOCYTE; CELL CULTURE; DRUG EFFECT; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; SIGNAL TRANSDUCTION; UPREGULATION;

ANTIGEN-PRESENTING CELLS; CELLS, CULTURED; CHEMOKINES; GENE PRODUCTS, TAT; HIV INFECTIONS; HIV-1; HUMANS; INTERFERON REGULATORY FACTOR-7; INTERFERONS; LYMPHOCYTE ACTIVATION; MAP KINASE KINASE 3; MAP KINASE KINASE 6; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, CHEMOKINE; SIGNAL TRANSDUCTION; UP-REGULATION;

MLCS; MLOWN;

EID: 84880979927     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-10-461566     Document Type: Article

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