메뉴 건너뛰기




Volumn 8, Issue 8, 2013, Pages

Regulation of A1 by OX40 Contributes to CD8+ T Cell Survival and Anti-Tumor Activity

Author keywords

[No Author keywords available]

Indexed keywords

BCL2 RELATED PROTEIN A1; CD134 ANTIGEN; GAMMA INTERFERON; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2;

EID: 84880979723     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070635     Document Type: Article
Times cited : (20)

References (41)
  • 1
    • 77952311199 scopus 로고    scopus 로고
    • Control of immunity by the TNFR-related molecule OX40 (CD134)
    • Croft M, (2010) Control of immunity by the TNFR-related molecule OX40 (CD134). Annu Rev Immunol 28: 57-78.
    • (2010) Annu Rev Immunol , vol.28 , pp. 57-78
    • Croft, M.1
  • 3
    • 24744454592 scopus 로고    scopus 로고
    • OX40 and Bcl-xL promote the persistence of CD8 T cells to recall tumor-associated antigen
    • Song A, Tang X, Harms KM, Croft M, (2005) OX40 and Bcl-xL promote the persistence of CD8 T cells to recall tumor-associated antigen. J Immunol 175: 3534-3541.
    • (2005) J Immunol , vol.175 , pp. 3534-3541
    • Song, A.1    Tang, X.2    Harms, K.M.3    Croft, M.4
  • 4
    • 33749128681 scopus 로고    scopus 로고
    • Functional dichotomy between OX40 and 4-1BB in modulating effector CD8 T cell responses
    • Lee SW, Park Y, Song A, Cheroutre H, Kwon BS, et al. (2006) Functional dichotomy between OX40 and 4-1BB in modulating effector CD8 T cell responses. J Immunol 177: 4464-4472.
    • (2006) J Immunol , vol.177 , pp. 4464-4472
    • Lee, S.W.1    Park, Y.2    Song, A.3    Cheroutre, H.4    Kwon, B.S.5
  • 5
    • 58749086427 scopus 로고    scopus 로고
    • OX40 costimulatory signals potentiate the memory commitment of effector CD8+ T cells
    • Mousavi SF, Soroosh P, Takahashi T, Yoshikai Y, Shen H, et al. (2008) OX40 costimulatory signals potentiate the memory commitment of effector CD8+ T cells. J Immunol 181: 5990-6001.
    • (2008) J Immunol , vol.181 , pp. 5990-6001
    • Mousavi, S.F.1    Soroosh, P.2    Takahashi, T.3    Yoshikai, Y.4    Shen, H.5
  • 6
    • 70249091483 scopus 로고    scopus 로고
    • Synergistic OX40 and CD30 signals sustain CD8+ T cells during antigenic challenge
    • Bekiaris V, Gaspal F, Kim MY, Withers DR, Sweet C, et al. (2009) Synergistic OX40 and CD30 signals sustain CD8+ T cells during antigenic challenge. Eur J Immunol 39: 2120-2125.
    • (2009) Eur J Immunol , vol.39 , pp. 2120-2125
    • Bekiaris, V.1    Gaspal, F.2    Kim, M.Y.3    Withers, D.R.4    Sweet, C.5
  • 7
    • 22544437564 scopus 로고    scopus 로고
    • During viral infection of the respiratory tract, CD27, 4-1BB, and OX40 collectively determine formation of CD8+ memory T cells and their capacity for secondary expansion
    • Hendriks J, Xiao Y, Rossen JW, van der Sluijs KF, Sugamura K, et al. (2005) During viral infection of the respiratory tract, CD27, 4-1BB, and OX40 collectively determine formation of CD8+ memory T cells and their capacity for secondary expansion. J Immunol 175: 1665-1676.
    • (2005) J Immunol , vol.175 , pp. 1665-1676
    • Hendriks, J.1    Xiao, Y.2    Rossen, J.W.3    van der Sluijs, K.F.4    Sugamura, K.5
  • 8
    • 34848849793 scopus 로고    scopus 로고
    • OX40 costimulation promotes persistence of cytomegalovirus-specific CD8 T Cells: A CD4-dependent mechanism
    • Humphreys IR, Loewendorf A, de Trez C, Schneider K, Benedict CA, et al. (2007) OX40 costimulation promotes persistence of cytomegalovirus-specific CD8 T Cells: A CD4-dependent mechanism. J Immunol 179: 2195-2202.
    • (2007) J Immunol , vol.179 , pp. 2195-2202
    • Humphreys, I.R.1    Loewendorf, A.2    de Trez, C.3    Schneider, K.4    Benedict, C.A.5
  • 10
    • 84856354852 scopus 로고    scopus 로고
    • An alternative signal 3: CD8(+) T cell memory independent of IL-12 and type I IFN is dependent on CD27/OX40 signaling
    • Sanchez PJ, Kedl RM, (2012) An alternative signal 3: CD8(+) T cell memory independent of IL-12 and type I IFN is dependent on CD27/OX40 signaling. Vaccine 30: 1154-1161.
    • (2012) Vaccine , vol.30 , pp. 1154-1161
    • Sanchez, P.J.1    Kedl, R.M.2
  • 12
    • 33846399187 scopus 로고    scopus 로고
    • Anti-OX40 stimulation in vivo enhances CD8+ memory T cell survival and significantly increases recall responses
    • Ruby CE, Redmond WL, Haley D, Weinberg AD, (2007) Anti-OX40 stimulation in vivo enhances CD8+ memory T cell survival and significantly increases recall responses. Eur J Immunol 37: 157-166.
    • (2007) Eur J Immunol , vol.37 , pp. 157-166
    • Ruby, C.E.1    Redmond, W.L.2    Haley, D.3    Weinberg, A.D.4
  • 13
    • 80052294659 scopus 로고    scopus 로고
    • Targeting OX40 promotes lung-resident memory CD8 T cell populations that protect against respiratory poxvirus infection
    • Salek-Ardakani S, Moutaftsi M, Sette A, Croft M, (2011) Targeting OX40 promotes lung-resident memory CD8 T cell populations that protect against respiratory poxvirus infection. J Virol 85: 9051-9059.
    • (2011) J Virol , vol.85 , pp. 9051-9059
    • Salek-Ardakani, S.1    Moutaftsi, M.2    Sette, A.3    Croft, M.4
  • 14
    • 78650939319 scopus 로고    scopus 로고
    • The TNFR family members OX40 and CD27 link viral virulence to protective T cell vaccines in mice
    • Salek-Ardakani S, Flynn R, Arens R, Yagita H, Smith GL, et al. (2011) The TNFR family members OX40 and CD27 link viral virulence to protective T cell vaccines in mice. J Clin Invest 121: 296-307.
    • (2011) J Clin Invest , vol.121 , pp. 296-307
    • Salek-Ardakani, S.1    Flynn, R.2    Arens, R.3    Yagita, H.4    Smith, G.L.5
  • 15
    • 30744445700 scopus 로고    scopus 로고
    • OX40 costimulation synergizes with GM-CSF whole-cell vaccination to overcome established CD8+ T cell tolerance to an endogenous tumor antigen
    • Murata S, Ladle BH, Kim PS, Lutz ER, Wolpoe ME, et al. (2006) OX40 costimulation synergizes with GM-CSF whole-cell vaccination to overcome established CD8+ T cell tolerance to an endogenous tumor antigen. J Immunol 176: 974-983.
    • (2006) J Immunol , vol.176 , pp. 974-983
    • Murata, S.1    Ladle, B.H.2    Kim, P.S.3    Lutz, E.R.4    Wolpoe, M.E.5
  • 16
    • 38849164304 scopus 로고    scopus 로고
    • Defects in the acquisition of CD8 T cell effector function after priming with tumor or soluble antigen can be overcome by the addition of an OX40 agonist
    • Redmond WL, Gough MJ, Charbonneau B, Ratliff TL, Weinberg AD, (2007) Defects in the acquisition of CD8 T cell effector function after priming with tumor or soluble antigen can be overcome by the addition of an OX40 agonist. J Immunol 179: 7244-7253.
    • (2007) J Immunol , vol.179 , pp. 7244-7253
    • Redmond, W.L.1    Gough, M.J.2    Charbonneau, B.3    Ratliff, T.L.4    Weinberg, A.D.5
  • 17
    • 48549099849 scopus 로고    scopus 로고
    • OX40 agonist therapy enhances CD8 infiltration and decreases immune suppression in the tumor
    • Gough MJ, Ruby CE, Redmond WL, Dhungel B, Brown A, et al. (2008) OX40 agonist therapy enhances CD8 infiltration and decreases immune suppression in the tumor. Cancer Res 68: 5206-5215.
    • (2008) Cancer Res , vol.68 , pp. 5206-5215
    • Gough, M.J.1    Ruby, C.E.2    Redmond, W.L.3    Dhungel, B.4    Brown, A.5
  • 18
    • 70249141660 scopus 로고    scopus 로고
    • Ligation of the OX40 co-stimulatory receptor reverses self-Ag and tumor-induced CD8 T-cell anergy in vivo
    • Redmond WL, Gough MJ, Weinberg AD, (2009) Ligation of the OX40 co-stimulatory receptor reverses self-Ag and tumor-induced CD8 T-cell anergy in vivo. Eur J Immunol 39: 2184-2194.
    • (2009) Eur J Immunol , vol.39 , pp. 2184-2194
    • Redmond, W.L.1    Gough, M.J.2    Weinberg, A.D.3
  • 19
    • 84870533238 scopus 로고    scopus 로고
    • Antitumor T-cell responses contribute to the effects of dasatinib on c-KIT mutant murine mastocytoma and are potentiated by anti-OX40
    • Yang Y, Liu C, Peng W, Lizee G, Overwijk WW, et al. (2012) Antitumor T-cell responses contribute to the effects of dasatinib on c-KIT mutant murine mastocytoma and are potentiated by anti-OX40. Blood 120: 4533-4543.
    • (2012) Blood , vol.120 , pp. 4533-4543
    • Yang, Y.1    Liu, C.2    Peng, W.3    Lizee, G.4    Overwijk, W.W.5
  • 20
    • 1142263117 scopus 로고    scopus 로고
    • The costimulation-regulated duration of PKB activation controls T cell longevity
    • Song J, Salek-Ardakani S, Rogers PR, Cheng M, Van Parijs L, et al. (2004) The costimulation-regulated duration of PKB activation controls T cell longevity. Nat Immunol 5: 150-158.
    • (2004) Nat Immunol , vol.5 , pp. 150-158
    • Song, J.1    Salek-Ardakani, S.2    Rogers, P.R.3    Cheng, M.4    Van Parijs, L.5
  • 21
    • 47249116959 scopus 로고    scopus 로고
    • Activation of NF-kappaB1 by OX40 contributes to antigen-driven T cell expansion and survival
    • Song J, So T, Croft M, (2008) Activation of NF-kappaB1 by OX40 contributes to antigen-driven T cell expansion and survival. J Immunol 180: 7240-7248.
    • (2008) J Immunol , vol.180 , pp. 7240-7248
    • Song, J.1    So, T.2    Croft, M.3
  • 22
    • 84862734168 scopus 로고    scopus 로고
    • Targeting antiapoptotic A1/Bfl-1 by in vivo RNAi reveals multiple roles in leukocyte development in mice
    • Ottina E, Grespi F, Tischner D, Soratroi C, Geley S, et al. (2012) Targeting antiapoptotic A1/Bfl-1 by in vivo RNAi reveals multiple roles in leukocyte development in mice. Blood 119: 6032-6042.
    • (2012) Blood , vol.119 , pp. 6032-6042
    • Ottina, E.1    Grespi, F.2    Tischner, D.3    Soratroi, C.4    Geley, S.5
  • 23
    • 77951730895 scopus 로고    scopus 로고
    • Defective ubiquitin-mediated degradation of antiapoptotic Bfl-1 predisposes to lymphoma
    • Fan G, Simmons MJ, Ge S, Dutta-Simmons J, Kucharczak J, et al. (2010) Defective ubiquitin-mediated degradation of antiapoptotic Bfl-1 predisposes to lymphoma. Blood 115: 3559-3569.
    • (2010) Blood , vol.115 , pp. 3559-3569
    • Fan, G.1    Simmons, M.J.2    Ge, S.3    Dutta-Simmons, J.4    Kucharczak, J.5
  • 24
    • 22344436226 scopus 로고    scopus 로고
    • Constitutive proteasome-mediated turnover of Bfl-1/A1 and its processing in response to TNF receptor activation in FL5.12 pro-B cells convert it into a prodeath factor
    • Kucharczak JF, Simmons MJ, Duckett CS, Gelinas C, (2005) Constitutive proteasome-mediated turnover of Bfl-1/A1 and its processing in response to TNF receptor activation in FL5.12 pro-B cells convert it into a prodeath factor. Cell Death Differ 12: 1225-1239.
    • (2005) Cell Death Differ , vol.12 , pp. 1225-1239
    • Kucharczak, J.F.1    Simmons, M.J.2    Duckett, C.S.3    Gelinas, C.4
  • 25
    • 33744951783 scopus 로고    scopus 로고
    • The stability and anti-apoptotic function of A1 are controlled by its C terminus
    • Herold MJ, Zeitz J, Pelzer C, Kraus C, Peters A, et al. (2006) The stability and anti-apoptotic function of A1 are controlled by its C terminus. J Biol Chem 281: 13663-13671.
    • (2006) J Biol Chem , vol.281 , pp. 13663-13671
    • Herold, M.J.1    Zeitz, J.2    Pelzer, C.3    Kraus, C.4    Peters, A.5
  • 26
    • 34548161868 scopus 로고    scopus 로고
    • Downregulation of Bfl-1 protein expression sensitizes malignant B cells to apoptosis
    • Brien G, Trescol-Biemont MC, Bonnefoy-Berard N, (2007) Downregulation of Bfl-1 protein expression sensitizes malignant B cells to apoptosis. Oncogene 26: 5828-5832.
    • (2007) Oncogene , vol.26 , pp. 5828-5832
    • Brien, G.1    Trescol-Biemont, M.C.2    Bonnefoy-Berard, N.3
  • 27
    • 0037769833 scopus 로고    scopus 로고
    • A1 is a growth-permissive antiapoptotic factor mediating postactivation survival in T cells
    • Gonzalez J, Orlofsky A, Prystowsky MB, (2003) A1 is a growth-permissive antiapoptotic factor mediating postactivation survival in T cells. Blood 101: 2679-2685.
    • (2003) Blood , vol.101 , pp. 2679-2685
    • Gonzalez, J.1    Orlofsky, A.2    Prystowsky, M.B.3
  • 28
    • 0036566250 scopus 로고    scopus 로고
    • Perturbation of B-cell development in mice overexpressing the Bcl-2 homolog A1
    • Chuang PI, Morefield S, Liu CY, Chen S, Harlan JM, et al. (2002) Perturbation of B-cell development in mice overexpressing the Bcl-2 homolog A1. Blood 99: 3350-3359.
    • (2002) Blood , vol.99 , pp. 3350-3359
    • Chuang, P.I.1    Morefield, S.2    Liu, C.Y.3    Chen, S.4    Harlan, J.M.5
  • 29
    • 67449155869 scopus 로고    scopus 로고
    • Cooperation between molecular targets of costimulation in promoting T cell persistence and tumor regression
    • Zhao B, Song A, Haque R, Lei F, Weiler L, et al. (2009) Cooperation between molecular targets of costimulation in promoting T cell persistence and tumor regression. J Immunol 182: 6744-6752.
    • (2009) J Immunol , vol.182 , pp. 6744-6752
    • Zhao, B.1    Song, A.2    Haque, R.3    Lei, F.4    Weiler, L.5
  • 30
    • 61949111202 scopus 로고    scopus 로고
    • Defining the target specificity of ABT-737 and synergistic antitumor activities in combination with histone deacetylase inhibitors
    • Whitecross KF, Alsop AE, Cluse LA, Wiegmans A, Banks KM, et al. (2009) Defining the target specificity of ABT-737 and synergistic antitumor activities in combination with histone deacetylase inhibitors. Blood 113: 1982-1991.
    • (2009) Blood , vol.113 , pp. 1982-1991
    • Whitecross, K.F.1    Alsop, A.E.2    Cluse, L.A.3    Wiegmans, A.4    Banks, K.M.5
  • 31
    • 19344374856 scopus 로고    scopus 로고
    • Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion
    • Song J, So T, Cheng M, Tang X, Croft M, (2005) Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion. Immunity 22: 621-631.
    • (2005) Immunity , vol.22 , pp. 621-631
    • Song, J.1    So, T.2    Cheng, M.3    Tang, X.4    Croft, M.5
  • 33
    • 20044368218 scopus 로고    scopus 로고
    • The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival
    • Mandal M, Borowski C, Palomero T, Ferrando AA, Oberdoerffer P, et al. (2005) The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival. J Exp Med 201: 603-614.
    • (2005) J Exp Med , vol.201 , pp. 603-614
    • Mandal, M.1    Borowski, C.2    Palomero, T.3    Ferrando, A.A.4    Oberdoerffer, P.5
  • 34
    • 0035803554 scopus 로고    scopus 로고
    • Essential role of the prosurvival bcl-2 homologue A1 in mast cell survival after allergic activation
    • Xiang Z, Ahmed AA, Moller C, Nakayama K, Hatakeyama S, et al. (2001) Essential role of the prosurvival bcl-2 homologue A1 in mast cell survival after allergic activation. J Exp Med 194: 1561-1569.
    • (2001) J Exp Med , vol.194 , pp. 1561-1569
    • Xiang, Z.1    Ahmed, A.A.2    Moller, C.3    Nakayama, K.4    Hatakeyama, S.5
  • 35
    • 0037083585 scopus 로고    scopus 로고
    • Deficiency in the anti-apoptotic protein A1-a results in a diminished acute inflammatory response
    • Orlofsky A, Weiss LM, Kawachi N, Prystowsky MB, (2002) Deficiency in the anti-apoptotic protein A1-a results in a diminished acute inflammatory response. J Immunol 168: 1840-1846.
    • (2002) J Immunol , vol.168 , pp. 1840-1846
    • Orlofsky, A.1    Weiss, L.M.2    Kawachi, N.3    Prystowsky, M.B.4
  • 36
    • 66149147044 scopus 로고    scopus 로고
    • Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia
    • Vogler M, Butterworth M, Majid A, Walewska RJ, Sun XM, et al. (2009) Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia. Blood 113: 4403-4413.
    • (2009) Blood , vol.113 , pp. 4403-4413
    • Vogler, M.1    Butterworth, M.2    Majid, A.3    Walewska, R.J.4    Sun, X.M.5
  • 37
    • 0034812971 scopus 로고    scopus 로고
    • OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells
    • Rogers PR, Song J, Gramaglia I, Killeen N, Croft M, (2001) OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells. Immunity 15: 445-455.
    • (2001) Immunity , vol.15 , pp. 445-455
    • Rogers, P.R.1    Song, J.2    Gramaglia, I.3    Killeen, N.4    Croft, M.5
  • 38
    • 79952585385 scopus 로고    scopus 로고
    • Antigen-independent signalosome of CARMA1, PKCtheta, and TNF receptor-associated factor 2 (TRAF2) determines NF-kappaB signaling in T cells
    • So T, Soroosh P, Eun SY, Altman A, Croft M, (2011) Antigen-independent signalosome of CARMA1, PKCtheta, and TNF receptor-associated factor 2 (TRAF2) determines NF-kappaB signaling in T cells. Proc Natl Acad Sci U S A 108: 2903-2908.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 2903-2908
    • So, T.1    Soroosh, P.2    Eun, S.Y.3    Altman, A.4    Croft, M.5
  • 39
    • 79953185367 scopus 로고    scopus 로고
    • OX40 complexes with phosphoinositide 3-kinase and protein kinase B (PKB) to augment TCR-dependent PKB signaling
    • So T, Choi H, Croft M, (2011) OX40 complexes with phosphoinositide 3-kinase and protein kinase B (PKB) to augment TCR-dependent PKB signaling. J Immunol 186: 3547-3555.
    • (2011) J Immunol , vol.186 , pp. 3547-3555
    • So, T.1    Choi, H.2    Croft, M.3
  • 40
    • 33847001284 scopus 로고    scopus 로고
    • The kinases aurora B and mTOR regulate the G1-S cell cycle progression of T lymphocytes
    • Song J, Salek-Ardakani S, So T, Croft M, (2007) The kinases aurora B and mTOR regulate the G1-S cell cycle progression of T lymphocytes. Nat Immunol 8: 64-73.
    • (2007) Nat Immunol , vol.8 , pp. 64-73
    • Song, J.1    Salek-Ardakani, S.2    So, T.3    Croft, M.4
  • 41
    • 0036838689 scopus 로고    scopus 로고
    • 4-1BB promotes the survival of CD8+ T lymphocytes by increasing expression of Bcl-xL and Bfl-1
    • Lee HW, Park SJ, Choi BK, Kim HH, Nam KO, et al. (2002) 4-1BB promotes the survival of CD8+ T lymphocytes by increasing expression of Bcl-xL and Bfl-1. J Immunol 169: 4882-4888.
    • (2002) J Immunol , vol.169 , pp. 4882-4888
    • Lee, H.W.1    Park, S.J.2    Choi, B.K.3    Kim, H.H.4    Nam, K.O.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.