Delivery of Nox2-NADPH oxidase siRNA with polyketal nanoparticles for improving cardiac function following myocardial infarction

Biomaterials

Volumn 34, Issue 31, 2013, Pages 7790-7798

  Somasuntharam, Inthirai ^a,b   Boopathy, Archana V ^a,b   Khan, Raffay S ^b   Martinez, Mario D ^a,b   Brown, Milton E ^b   Murthy, Niren ^c   Davis, Michael E ^a,b  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c University of California   (United States)

Author keywords

Gene expression; Gene silencing; Macrophages; Myocardial infarction; Nanoparticles

Indexed keywords

CARDIAC FUNCTIONS; CARDIAC REMODELING; CATALYTIC SUBUNITS; GENE SILENCING; ISCHEMIC INJURIES; MYOCARDIAL INFARCTION; REACTIVE OXYGEN SPECIES; THERAPEUTIC TARGETS;

GENE EXPRESSION; GENE THERAPY; GENETIC ENGINEERING; MACROPHAGES; MAMMALS; NANOPARTICLES;

HEART;

REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SMALL INTERFERING RNA;

ANIMAL TISSUE; ARTICLE; ENCAPSULATION; GENE EXPRESSION; GENE SILENCING; HEART FUNCTION; HEART INFARCTION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

MUS;

EID: 84880963867     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.06.051     Document Type: Article

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