The delivery of superoxide dismutase encapsulated in polyketal microparticles to rat myocardium and protection from myocardial ischemia-reperfusion injury

Biomaterials

Volumn 31, Issue 6, 2010, Pages 1372-1379

  Seshadri, Gokulakrishnan ^a   Sy, Jay C ^a   Brown, Milton ^a   Dikalov, Sergey ^b   Yang, Stephen C ^a   Murthy, Niren ^a   Davis, Michael E ^a,b  

^a Emory University   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antioxidant; Apoptosis; Free radical; Microencapsulation

Indexed keywords

ANTIOXIDANT; APOPTOSIS; CARDIAC FUNCTIONS; CARDIAC MYOCYTES; CARDIAC REPAIR; CU/ZN-SUPEROXIDE DISMUTASE; DELIVERY VEHICLE; EXTRACELLULAR; GENE THERAPY; ISCHEMIA/REPERFUSION; MICRO-PARTICLES; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA-REPERFUSION INJURIES; RAT MODEL; SUPER OXIDE DISMUTASE; SUPEROXIDES;

AUTOMOBILE EXHIBITIONS; CELL DEATH; DRUG PRODUCTS; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; FREE RADICALS; GENETIC ENGINEERING; PACKAGING; PROTEINS;

OXYGEN;

COPPER ZINC SUPEROXIDE DISMUTASE; POLY(CYCLOHEXANE 1,4DIYL ACETONE DIMETHYLENE KETAL); POLYMER; SUPEROXIDE; UNCLASSIFIED DRUG;

ADULT ANIMAL; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; ECHOCARDIOGRAPHY; ENCAPSULATION; GENE DELIVERY SYSTEM; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

ANIMALS; DRUG CARRIERS; DRUG COMPOUNDING; FREE RADICAL SCAVENGERS; MICROSPHERES; MYOCARDIAL REPERFUSION INJURY; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; TREATMENT OUTCOME;

RATTUS;

EID: 72149126107     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.10.045     Document Type: Article

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