Il-1β mediates leptin induction during inflammation

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 274, Issue 1 43-1, 1998, Pages

  Faggioni, Raffaella ^a   Fantuzzi, Giamila ^b   Fuller, John ^a   Dinarello, Charles A ^b   Feingold, Kenneth R ^a   Grunfeld, Carl ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Endotoxin; Interleukin 1 ; Interleukin 6; Knockout mice; Lipopolysaccharide; Ob protein; Turpentine

Indexed keywords

INTERLEUKIN 1BETA; LEPTIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; TURPENTINE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HORMONE SYNTHESIS; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; TISSUE INJURY;

EID: 0031939531     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1998.274.1.r204     Document Type: Article

References (33)

1. Ahima, R. S., D. Prabakaran, C. Mantzoros, D. Qu, B. Lowell, E. Maratos-Flier, and J. S. Flier. Role of leptin in the neuroendocrine response to fasting. Nature 382: 250-252, 1996.
2. Barash, I. A., C. C. Cheung, D. S. Weigle, H. Ren, E. B. Kabisting, J. L. Kuijper, D. K. Clifton, and R. A. Steiner. Leptin is a metabolic signal to the reproductive system. Endocrinology 137: 3144-3147, 1996.
3. Chai, Z., S. Gatti, C. Toniatti, V. Poli, and T. Bartfai. Interleukin (IL)-6 gene expression in the central nervous system is necessary for fever response to lipolysaccharide or IL-1β: a study on IL-6-deficient mice. J. Exp. Med. 183: 311-316, 1996.
4. Chen, H., O. Charlat, L. A. Tartaglia, E. A. Woolf, X. Weng, S. J. Ellis, N. D. Lakey, J. Culpepper, K. J. Moore, R. E. Breitbart, G. M. Duyk, R. I. Tepper, and J. P. Morgenstern. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 84: 491-495, 1996.
5. Chomczynski, P., and N. Sacchi. Single step method of RNA isolation by acid guanidium tiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 150-159, 1987.
6. Considine, R. V., M. K. Sinha, M. L. Heiman, A. Kriauciunas, T. W. Stephens, M. R. Nyce, J. P. Ohannesian, C. C. Marco, L. J. McKee, T. L. Bauer, and J. F. Caro. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N. Engl. J. Med. 334: 292-325, 1996.
7. Dascombe, M. J., A. Hardwick, R. A. Lefeuvre, and N. J. Rothwell. Impaired effects of interleukin-1β on fever and thermogenesis in genetically obese rats. Int. J. Obes. 13: 367-373, 1989.
8. Dinarello, C. A. Biological basis for interleukin-1 in disease. Blood 87: 2095-2147, 1996.
9. Faggioni, R., J. Fuller, A. Moser, K. R. Feingold, and C. Grunfeld. LPS-induced anorexia in leptin-deficient (ob/ob) and leptin receptor-deficient (db/db) mice. Am. J. Physiol. 273 (Regulatory Integrative Comp. Physiol. 42): R181-R186, 1997.
10. Fantuzzi, G., and C. A. Dinarello. The inflammatory response in interleukin-1β-deficient mice: comparison with other cytokine-related knock-out mice. J. Leukoc. Biol. 59: 489-493, 1996.
11. Fantuzzi, G., G. Ku, M. W. Harding, D. J. Livingston, K. Kuida, R. A. Flavell, and C. A. Dinarello. Response to local inflammation of IL-1β converting enzyme-deficient mice. J. Immunol. 158: 1818-1824, 1997.
12. Fantuzzi, G., H. Zheng, R. Faggioni, F. Benigni, P. Ghezzi, J. D. Sipe, A. R. Shaw, and C. A. Dinarello. Effect of endotoxin in interleukin-1β-deficient mice. J. Immunol. 157: 291-296, 1996.
13. Fattori, E., M. Cappelletti, P. Costa, C. Sellitto, L. Cantoni, M. Carelli, R. Faggioni, G. Fantuzzi, P. Ghezzi, and V. Poli. Defective inflammatory response in interleukin-6 deficient mice. J. Exp. Med. 180: 1243-1250, 1994.
14. Feingold, K. R., A. L. Pollock, A. H. Moser, J. K. Shigenaga, and C. Grunfeld. Effect of endotoxin on cholesterol metabolism during the acute phase response. J. Lipid Res. 34: 2147-2158, 1993.
15. Feingold, K. R., A. L. Pollock, A. H. Moser, J. K. Shigenaga, and C. Grunfeld. Discordant regulation of proteins of cholesterol metabolism during the acute phase response. J. Lipid Res. 36: 1474-1482, 1995.
16. Gainsford, T., T. A. Willson, D. Metcalf, E. Handman, C. McFarlane, A. Ng, N. A. Nicola, W. S. Alexander, and D. J. Hilton. Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells. Proc. Natl. Acad. Sci. USA 93: 14564-14568, 1996.
17. Grunfeld, C., C. Zhao, J. Fuller, A. Pollock, A. Moser, J. Friedman, and K. R. Feingold. Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters. A role for leptin in the anorexia of infection. J. Clin. Invest. 97: 2152-2157, 1996.
18. Hardardottir, I., A. H. Moser, J. Juller, C. Fielding, K. R. Feingold, and C. Grunfeld. Endotoxin and cytokines decrease serum levels of cholesteryl ester transfer protein and mRNA levels in Syrian hamsters. J. Clin. Invest. 97: 2152-2157, 1996.
19. Kopf, M., H. Baumann, G. Freer, M. Freudenberg, M. Lamers, T. Kishimoto, R. Zinkernagel, H. Bluethmann, and G. Kohler. Impaired immune and acute-phase responses in interleukin-6-deficient mice. Nature 368: 339-342, 1994.
20. Long, N. C., I. Otterness, S. L. Kunkel, A. J. Vander, and M. J. Kluger. Role of interleukin 1β and tumor necrosis factor in lipopolysaccharide fever in rats. Am. J. Physiol. 259 (Regulatory Integrative Comp. Physiol. 28): R724-R728, 1990.
21. Ly, H., O. L. Francone, C. J. Fielding, J. K. Shigenaga, A. H. Moser, C. Grunfeld, and K. R. Feingold. Endotoxin and TNF lead to reduced plasma LCAT activity and decreased LCAT mRNA levels in Syrian hamsters. J. Lipid Res. 36: 1254-1263, 1995.
22. Maffei, M., J. Halaas, E. Ravussin, R. E. Pratley, G. H. Lee, Y. Zhang, H. Fei, R. Kim, R. Lallone, S. Ranganathan, P. A. Kern, and J. M. Friedman. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat. Med. 1: 1155-1161, 1995.
23. Mikhail, A. A., E. X. Beck, A. Shafer, B. Barut, J. S. Gbur, T. J. Zupancic, A. C. Schweitzer, J. A. Cioffi, G. Lacaud, B. Ouyang, G. Keller, and H. R. Snodgrass. Leptin stimulates fetal and adult erythroid and myeloid development. Blood 5: 1507-1512, 1997.
24. Murakami, T., T. Yamashita, M. Iida, M. Kuwajiama, and K. Shima. A short form of leptin receptor performs signal transduction. Biochem. Biophys. Res. Commun. 231: 26-29, 1997.
25. Pelleymounter, M. A., M. J. Cullen, M. B. Baker, R. Hecht, D. Winters, T. Boone, and F. Collins. Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269: 540-543, 1995.
26. Plata-Salaman, C. R. Anorexia during acute and chronic disease. Nutrition 12: 69-78, 1996.
27. Plata-Salaman, C. R., J. R. Vaselli, and G. Sonti. Differential responsiveness of obese (fa/fa) and lean (Fa/Fa) Zucker rats to cytokine-induced anorexia. Obes. Res. 5: 36-42, 1997.
28. Sarraf, P., R. C. Frederich, E. M. Turner, G. Ma, N. T. Jaskowiak, D. J. Rivet, J. S. Flier, B. B. Lowell, D. L. Fraker, and H. R. Alexander. Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia. J. Exp. Med. 185: 171-175, 1997.
29. Schwartz, G. J., C. R. Plata-Salaman, and W. Langhans. Subdiaphragmatic vagal deafferentation fails to block feeding-suppressive effects of LPS and IL-1β in rats. Am. J. Physiol. 273 (Regulatory Integrative Comp. Physiol. 42): R1193-R1198, 1997.
30. Sonti, G., S. E. Ilyin, and C. R. Plata-Salaman. Anorexia induced by cytokine interactions at pathophysiological concentrations. Am. J. Physiol. 270 (Regulatory Integrative Comp. Physiol. 39): R1394-R1402, 1996.
31. Tartaglia, L. A., M. Dembski, X. Weng, N. Deng, J. Culpepper, R. Devos, G. J. Richards, L. A. Campfield, F. T. Clark, J. Deeds, C. Muir, S. Sanker, A. Moriarty, K. J. Moore, J. S. Smutko, G. G. Mays, E. A. Woolf, C. A. Monroe, and R. I. Tepper. Identification and expression cloning of a leptin receptor, OB-R. Cell 83: 1263-1271, 1995.
32. Zhang, Y., R. Proenca, M. Maffei, M. Barone, L. Leopold, and J. M. Friedman. Positional cloning of the mouse obese gene and its human homologue. Nature 372: 425-432, 1994.
33. Zheng, H., D. Fletcher, W. Kozak, M. Jiang, K. Hofmann, C. A. Conn, D. Soszynski, C. Grabiec, M. E. Trumbauer, A. Shaw, M. J. Kostura, K. Stevens, H. Rosen, R. J. North, H. Y. Chen, M. J. Tocci, M. J. Kluger, and L. H. T. Van der Ploeg. Resistance to fever induction and impaired acute-phase response in interleukin-1β deficient mice. Immunity 3: 9-19, 1995.