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Volumn 56, Issue , 2013, Pages 255-262

Role of the cannabinoid system in the transit of beta-amyloid across the blood-brain barrier

Author keywords

Alzheimer's disease; Amyloid; Blood brain barrier; Cannabinoid; Clearance; Low density lipoprotein receptor related protein 1

Indexed keywords

AMYLOID BETA PROTEIN; CANNABINOID; CANNABINOID RECEPTOR; CANNABINOID RECEPTOR AGONIST; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN;

EID: 84880934071     PISSN: 10447431     EISSN: 10959327     Source Type: Journal    
DOI: 10.1016/j.mcn.2013.06.004     Document Type: Article
Times cited : (44)

References (60)
  • 2
    • 84861513395 scopus 로고    scopus 로고
    • CB1 agonist ACEA protects neurons and reduces the cognitive impairment of AbetaPP/PS1 mice
    • Aso E., Palomer E., Juves S., Maldonado R., Munoz F.J., Ferrer I. CB1 agonist ACEA protects neurons and reduces the cognitive impairment of AbetaPP/PS1 mice. J. Alzheimers Dis. 2012, 30:439-459.
    • (2012) J. Alzheimers Dis. , vol.30 , pp. 439-459
    • Aso, E.1    Palomer, E.2    Juves, S.3    Maldonado, R.4    Munoz, F.J.5    Ferrer, I.6
  • 3
    • 78651497015 scopus 로고    scopus 로고
    • Characterization and use of human brain microvascular endothelial cells to examine beta-amyloid exchange in the blood-brain barrier
    • Bachmeier C., Mullan M., Paris D. Characterization and use of human brain microvascular endothelial cells to examine beta-amyloid exchange in the blood-brain barrier. Cytotechnology 2010, 62:519-529.
    • (2010) Cytotechnology , vol.62 , pp. 519-529
    • Bachmeier, C.1    Mullan, M.2    Paris, D.3
  • 4
    • 79959850883 scopus 로고    scopus 로고
    • Epitope-dependent effects of beta-amyloid antibodies on beta-amyloid clearance in an in vitro model of the blood-brain barrier
    • Bachmeier C.J., Beaulieu-Abdelahad D., Mullan M.J., Paris D. Epitope-dependent effects of beta-amyloid antibodies on beta-amyloid clearance in an in vitro model of the blood-brain barrier. Microcirculation 2011, 18:373-379.
    • (2011) Microcirculation , vol.18 , pp. 373-379
    • Bachmeier, C.J.1    Beaulieu-Abdelahad, D.2    Mullan, M.J.3    Paris, D.4
  • 6
    • 0036011159 scopus 로고    scopus 로고
    • Fatty acid amide hydrolase, an enzyme with many bioactive substrates. Possible therapeutic implications
    • Bisogno T., De Petrocellis L., Di Marzo V. Fatty acid amide hydrolase, an enzyme with many bioactive substrates. Possible therapeutic implications. Curr. Pharm. Des. 2002, 8:533-547.
    • (2002) Curr. Pharm. Des. , vol.8 , pp. 533-547
    • Bisogno, T.1    De Petrocellis, L.2    Di Marzo, V.3
  • 7
    • 22144477527 scopus 로고    scopus 로고
    • Anandamide induced PPARgamma transcriptional activation and 3T3-L1 preadipocyte differentiation
    • Bouaboula M., Hilairet S., Marchand J., Fajas L., Le Fur G., Casellas P. Anandamide induced PPARgamma transcriptional activation and 3T3-L1 preadipocyte differentiation. Eur. J. Pharmacol. 2005, 517:174-181.
    • (2005) Eur. J. Pharmacol. , vol.517 , pp. 174-181
    • Bouaboula, M.1    Hilairet, S.2    Marchand, J.3    Fajas, L.4    Le Fur, G.5    Casellas, P.6
  • 8
    • 35648944275 scopus 로고    scopus 로고
    • Alzheimer's disease; taking the edge off with cannabinoids?
    • Campbell V.A., Gowran A. Alzheimer's disease; taking the edge off with cannabinoids?. Br. J. Pharmacol. 2007, 152:655-662.
    • (2007) Br. J. Pharmacol. , vol.152 , pp. 655-662
    • Campbell, V.A.1    Gowran, A.2
  • 10
    • 84870412999 scopus 로고    scopus 로고
    • Monoacylglycerol lipase is a therapeutic target for Alzheimer's disease
    • Chen R., Zhang J., Wu Y., Wang D., Feng G., Tang Y.P., Teng Z., Chen C. Monoacylglycerol lipase is a therapeutic target for Alzheimer's disease. Cell Rep. 2012, 2:1329-1339.
    • (2012) Cell Rep. , vol.2 , pp. 1329-1339
    • Chen, R.1    Zhang, J.2    Wu, Y.3    Wang, D.4    Feng, G.5    Tang, Y.P.6    Teng, Z.7    Chen, C.8
  • 11
    • 77951776829 scopus 로고    scopus 로고
    • Alzheimer's disease: strategies for disease modification
    • Citron M. Alzheimer's disease: strategies for disease modification. Nat. Rev. Drug Discov. 2010, 9:387-398.
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 387-398
    • Citron, M.1
  • 12
    • 48949117577 scopus 로고    scopus 로고
    • The role of the cell surface LRP and soluble LRP in blood-brain barrier Abeta clearance in Alzheimer's disease
    • Deane R., Sagare A., Zlokovic B.V. The role of the cell surface LRP and soluble LRP in blood-brain barrier Abeta clearance in Alzheimer's disease. Curr. Pharm. Des. 2008, 14:1601-1605.
    • (2008) Curr. Pharm. Des. , vol.14 , pp. 1601-1605
    • Deane, R.1    Sagare, A.2    Zlokovic, B.V.3
  • 14
    • 77951150250 scopus 로고    scopus 로고
    • Neuronal death in Alzheimer's disease and therapeutic opportunities
    • Donev R., Kolev M., Millet B., Thome J. Neuronal death in Alzheimer's disease and therapeutic opportunities. J. Cell. Mol. Med. 2009, 13:4329-4348.
    • (2009) J. Cell. Mol. Med. , vol.13 , pp. 4329-4348
    • Donev, R.1    Kolev, M.2    Millet, B.3    Thome, J.4
  • 15
    • 79960310251 scopus 로고    scopus 로고
    • Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-gamma
    • Du H., Chen X., Zhang J., Chen C. Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-gamma. Br. J. Pharmacol. 2011, 163:1533-1549.
    • (2011) Br. J. Pharmacol. , vol.163 , pp. 1533-1549
    • Du, H.1    Chen, X.2    Zhang, J.3    Chen, C.4
  • 17
    • 0023832275 scopus 로고
    • Stimulation of lipolytic enzymes in Alzheimer's disease
    • Farooqui A.A., Liss L., Horrocks L.A. Stimulation of lipolytic enzymes in Alzheimer's disease. Ann. Neurol. 1988, 23:306-308.
    • (1988) Ann. Neurol. , vol.23 , pp. 306-308
    • Farooqui, A.A.1    Liss, L.2    Horrocks, L.A.3
  • 18
    • 77951689435 scopus 로고    scopus 로고
    • Biomarkers of oxidative damage and inflammation in Alzheimer's disease
    • Galasko D., Montine T.J. Biomarkers of oxidative damage and inflammation in Alzheimer's disease. Biomark. Med. 2010, 4:27-36.
    • (2010) Biomark. Med. , vol.4 , pp. 27-36
    • Galasko, D.1    Montine, T.J.2
  • 19
    • 0038823590 scopus 로고    scopus 로고
    • Adipocyte low density lipoprotein receptor-related protein gene expression and function is regulated by peroxisome proliferator-activated receptor gamma
    • Gauthier A., Vassiliou G., Benoist F., McPherson R. Adipocyte low density lipoprotein receptor-related protein gene expression and function is regulated by peroxisome proliferator-activated receptor gamma. J. Biol. Chem. 2003, 278:11945-11953.
    • (2003) J. Biol. Chem. , vol.278 , pp. 11945-11953
    • Gauthier, A.1    Vassiliou, G.2    Benoist, F.3    McPherson, R.4
  • 21
    • 84862314657 scopus 로고    scopus 로고
    • Methylhonokiol attenuates neuroinflammation: a role for cannabinoid receptors?
    • Gertsch J., Anavi-Goffer S. Methylhonokiol attenuates neuroinflammation: a role for cannabinoid receptors?. J. Neuroinflammation 2012, 9:135.
    • (2012) J. Neuroinflammation , vol.9 , pp. 135
    • Gertsch, J.1    Anavi-Goffer, S.2
  • 23
    • 84859912791 scopus 로고    scopus 로고
    • CB1 cannabinoid receptor activation rescues amyloid beta-induced alterations in behaviour and intrinsic electrophysiological properties of rat hippocampal CA1 pyramidal neurones
    • Haghani M., Shabani M., Javan M., Motamedi F., Janahmadi M. CB1 cannabinoid receptor activation rescues amyloid beta-induced alterations in behaviour and intrinsic electrophysiological properties of rat hippocampal CA1 pyramidal neurones. Cell. Physiol. Biochem. 2012, 29:391-406.
    • (2012) Cell. Physiol. Biochem. , vol.29 , pp. 391-406
    • Haghani, M.1    Shabani, M.2    Javan, M.3    Motamedi, F.4    Janahmadi, M.5
  • 24
    • 84855998880 scopus 로고    scopus 로고
    • Contrasting protective effects of cannabinoids against oxidative stress and amyloid-beta evoked neurotoxicity in vitro
    • Harvey B.S., Ohlsson K.S., Maag J.L., Musgrave I.F., Smid S.D. Contrasting protective effects of cannabinoids against oxidative stress and amyloid-beta evoked neurotoxicity in vitro. Neurotoxicology 2012, 33:138-146.
    • (2012) Neurotoxicology , vol.33 , pp. 138-146
    • Harvey, B.S.1    Ohlsson, K.S.2    Maag, J.L.3    Musgrave, I.F.4    Smid, S.D.5
  • 25
    • 33847635165 scopus 로고    scopus 로고
    • Endothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerol
    • Ho W.S., Randall M.D. Endothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerol. Br. J. Pharmacol. 2007, 150:641-651.
    • (2007) Br. J. Pharmacol. , vol.150 , pp. 641-651
    • Ho, W.S.1    Randall, M.D.2
  • 27
    • 27644433182 scopus 로고    scopus 로고
    • Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects
    • Jiang W., Zhang Y., Xiao L., Van Cleemput J., Ji S.P., Bai G., Zhang X. Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects. J. Clin. Invest. 2005, 115:3104-3116.
    • (2005) J. Clin. Invest. , vol.115 , pp. 3104-3116
    • Jiang, W.1    Zhang, Y.2    Xiao, L.3    Van Cleemput, J.4    Ji, S.P.5    Bai, G.6    Zhang, X.7
  • 29
    • 84858984433 scopus 로고    scopus 로고
    • CB1 receptor antagonists: new discoveries leading to new perspectives
    • Kirilly E., Gonda X., Bagdy G. CB1 receptor antagonists: new discoveries leading to new perspectives. Acta Physiol. (Oxf.) 2012, 205:41-60.
    • (2012) Acta Physiol. (Oxf.) , vol.205 , pp. 41-60
    • Kirilly, E.1    Gonda, X.2    Bagdy, G.3
  • 31
    • 0036830947 scopus 로고    scopus 로고
    • Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
    • LaFerla F.M. Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease. Nat. Rev. Neurosci. 2002, 3:862-872.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 862-872
    • LaFerla, F.M.1
  • 32
    • 34250819839 scopus 로고    scopus 로고
    • Intracellular amyloid-beta in Alzheimer's disease
    • LaFerla F.M., Green K.N., Oddo S. Intracellular amyloid-beta in Alzheimer's disease. Nat. Rev. Neurosci. 2007, 8:499-509.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 499-509
    • LaFerla, F.M.1    Green, K.N.2    Oddo, S.3
  • 35
    • 33645537283 scopus 로고    scopus 로고
    • Regulation by cannabinoid receptors of anandamide transport across the blood-brain barrier and through other endothelial cells
    • Maccarrone M., Fiori A., Bari M., Granata F., Gasperi V., De Stefano M.E., Finazzi-Agro A., Strom R. Regulation by cannabinoid receptors of anandamide transport across the blood-brain barrier and through other endothelial cells. Thromb. Haemost. 2006, 95:117-127.
    • (2006) Thromb. Haemost. , vol.95 , pp. 117-127
    • Maccarrone, M.1    Fiori, A.2    Bari, M.3    Granata, F.4    Gasperi, V.5    De Stefano, M.E.6    Finazzi-Agro, A.7    Strom, R.8
  • 36
    • 84855813696 scopus 로고    scopus 로고
    • Can the benefits of cannabinoid receptor stimulation on neuroinflammation, neurogenesis and memory during normal aging be useful in AD prevention?
    • Marchalant Y., Baranger K., Wenk G.L., Khrestchatisky M., Rivera S. Can the benefits of cannabinoid receptor stimulation on neuroinflammation, neurogenesis and memory during normal aging be useful in AD prevention?. J. Neuroinflammation 2012, 9:10.
    • (2012) J. Neuroinflammation , vol.9 , pp. 10
    • Marchalant, Y.1    Baranger, K.2    Wenk, G.L.3    Khrestchatisky, M.4    Rivera, S.5
  • 42
    • 34548703093 scopus 로고    scopus 로고
    • Amyloid beta protein as a marker or risk factor of Alzheimer's disease
    • Mehta P.D. Amyloid beta protein as a marker or risk factor of Alzheimer's disease. Curr. Alzheimer Res. 2007, 4:359-363.
    • (2007) Curr. Alzheimer Res. , vol.4 , pp. 359-363
    • Mehta, P.D.1
  • 43
    • 0037206662 scopus 로고    scopus 로고
    • Anandamide and noladin ether prevent neurotoxicity of the human amyloid-beta peptide
    • Milton N.G. Anandamide and noladin ether prevent neurotoxicity of the human amyloid-beta peptide. Neurosci. Lett. 2002, 332:127-130.
    • (2002) Neurosci. Lett. , vol.332 , pp. 127-130
    • Milton, N.G.1
  • 45
    • 43849095304 scopus 로고    scopus 로고
    • Amyloid imaging in Alzheimer's disease
    • Nordberg A. Amyloid imaging in Alzheimer's disease. Neuropsychologia 2008, 46:1636-1641.
    • (2008) Neuropsychologia , vol.46 , pp. 1636-1641
    • Nordberg, A.1
  • 46
    • 35649008926 scopus 로고    scopus 로고
    • Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors
    • O'Sullivan S.E. Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors. Br. J. Pharmacol. 2007, 152:576-582.
    • (2007) Br. J. Pharmacol. , vol.152 , pp. 576-582
    • O'Sullivan, S.E.1
  • 47
    • 80053024234 scopus 로고    scopus 로고
    • Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice
    • Pan B., Wang W., Zhong P., Blankman J.L., Cravatt B.F., Liu Q.S. Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice. J. Neurosci. 2011, 31:13420-13430.
    • (2011) J. Neurosci. , vol.31 , pp. 13420-13430
    • Pan, B.1    Wang, W.2    Zhong, P.3    Blankman, J.L.4    Cravatt, B.F.5    Liu, Q.S.6
  • 50
    • 33745280979 scopus 로고    scopus 로고
    • Interleukin-2 suppression by 2-arachidonyl glycerol is mediated through peroxisome proliferator-activated receptor gamma independently of cannabinoid receptors 1 and 2
    • Rockwell C.E., Snider N.T., Thompson J.T., Vanden Heuvel J.P., Kaminski N.E. Interleukin-2 suppression by 2-arachidonyl glycerol is mediated through peroxisome proliferator-activated receptor gamma independently of cannabinoid receptors 1 and 2. Mol. Pharmacol. 2006, 70:101-111.
    • (2006) Mol. Pharmacol. , vol.70 , pp. 101-111
    • Rockwell, C.E.1    Snider, N.T.2    Thompson, J.T.3    Vanden Heuvel, J.P.4    Kaminski, N.E.5
  • 53
    • 84855359304 scopus 로고    scopus 로고
    • The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors
    • Savinainen J.R., Saario S.M., Laitinen J.T. The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors. Acta Physiol. (Oxf.) 2012, 204:267-276.
    • (2012) Acta Physiol. (Oxf.) , vol.204 , pp. 267-276
    • Savinainen, J.R.1    Saario, S.M.2    Laitinen, J.T.3
  • 54
    • 77952651099 scopus 로고    scopus 로고
    • The endocannabinoid system as a target for the treatment of neurodegenerative disease
    • Scotter E.L., Abood M.E., Glass M. The endocannabinoid system as a target for the treatment of neurodegenerative disease. Br. J. Pharmacol. 2010, 160:480-498.
    • (2010) Br. J. Pharmacol. , vol.160 , pp. 480-498
    • Scotter, E.L.1    Abood, M.E.2    Glass, M.3
  • 55
    • 0031706164 scopus 로고    scopus 로고
    • Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity
    • Shen M., Thayer S.A. Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity. Mol. Pharmacol. 1998, 54:459-462.
    • (1998) Mol. Pharmacol. , vol.54 , pp. 459-462
    • Shen, M.1    Thayer, S.A.2
  • 57
    • 33745195042 scopus 로고    scopus 로고
    • Biochemistry, pharmacology and physiology of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand
    • Sugiura T., Kishimoto S., Oka S., Gokoh M. Biochemistry, pharmacology and physiology of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand. Prog. Lipid Res. 2006, 45:405-446.
    • (2006) Prog. Lipid Res. , vol.45 , pp. 405-446
    • Sugiura, T.1    Kishimoto, S.2    Oka, S.3    Gokoh, M.4
  • 59
    • 67349118757 scopus 로고    scopus 로고
    • Microvasculature changes and cerebral amyloid angiopathy in Alzheimer's disease and their potential impact on therapy
    • Weller R.O., Boche D., Nicoll J.A. Microvasculature changes and cerebral amyloid angiopathy in Alzheimer's disease and their potential impact on therapy. Acta Neuropathol. 2009, 118:87-102.
    • (2009) Acta Neuropathol. , vol.118 , pp. 87-102
    • Weller, R.O.1    Boche, D.2    Nicoll, J.A.3
  • 60
    • 84870489074 scopus 로고    scopus 로고
    • Activation of the CB(2) receptor system reverses amyloid-induced memory deficiency
    • Wu J., Bie B., Yang H., Xu J.J., Brown D.L., Naguib M. Activation of the CB(2) receptor system reverses amyloid-induced memory deficiency. Neurobiol. Aging 2013, 34:791-804.
    • (2013) Neurobiol. Aging , vol.34 , pp. 791-804
    • Wu, J.1    Bie, B.2    Yang, H.3    Xu, J.J.4    Brown, D.L.5    Naguib, M.6


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