-
1
-
-
34548241342
-
The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis
-
Aguado T., Romero E., Monory K., Palazuelos J., Sendtner M., Marsicano G., Lutz B., Guzman M., Galve-Roperh I. The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis. J. Biol. Chem. 2007, 282:23892-23898.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 23892-23898
-
-
Aguado, T.1
Romero, E.2
Monory, K.3
Palazuelos, J.4
Sendtner, M.5
Marsicano, G.6
Lutz, B.7
Guzman, M.8
Galve-Roperh, I.9
-
2
-
-
84861513395
-
CB1 agonist ACEA protects neurons and reduces the cognitive impairment of AbetaPP/PS1 mice
-
Aso E., Palomer E., Juves S., Maldonado R., Munoz F.J., Ferrer I. CB1 agonist ACEA protects neurons and reduces the cognitive impairment of AbetaPP/PS1 mice. J. Alzheimers Dis. 2012, 30:439-459.
-
(2012)
J. Alzheimers Dis.
, vol.30
, pp. 439-459
-
-
Aso, E.1
Palomer, E.2
Juves, S.3
Maldonado, R.4
Munoz, F.J.5
Ferrer, I.6
-
3
-
-
78651497015
-
Characterization and use of human brain microvascular endothelial cells to examine beta-amyloid exchange in the blood-brain barrier
-
Bachmeier C., Mullan M., Paris D. Characterization and use of human brain microvascular endothelial cells to examine beta-amyloid exchange in the blood-brain barrier. Cytotechnology 2010, 62:519-529.
-
(2010)
Cytotechnology
, vol.62
, pp. 519-529
-
-
Bachmeier, C.1
Mullan, M.2
Paris, D.3
-
4
-
-
79959850883
-
Epitope-dependent effects of beta-amyloid antibodies on beta-amyloid clearance in an in vitro model of the blood-brain barrier
-
Bachmeier C.J., Beaulieu-Abdelahad D., Mullan M.J., Paris D. Epitope-dependent effects of beta-amyloid antibodies on beta-amyloid clearance in an in vitro model of the blood-brain barrier. Microcirculation 2011, 18:373-379.
-
(2011)
Microcirculation
, vol.18
, pp. 373-379
-
-
Bachmeier, C.J.1
Beaulieu-Abdelahad, D.2
Mullan, M.J.3
Paris, D.4
-
5
-
-
84866415195
-
A multifaceted role for apoE in the clearance of beta-amyloid across the blood-brain barrier
-
Bachmeier C., Paris D., Beaulieu-Abdelahad D., Mouzon B., Mullan M., Crawford F. A multifaceted role for apoE in the clearance of beta-amyloid across the blood-brain barrier. Neurodegener. Dis. 2013, 11:13-21.
-
(2013)
Neurodegener. Dis.
, vol.11
, pp. 13-21
-
-
Bachmeier, C.1
Paris, D.2
Beaulieu-Abdelahad, D.3
Mouzon, B.4
Mullan, M.5
Crawford, F.6
-
6
-
-
0036011159
-
Fatty acid amide hydrolase, an enzyme with many bioactive substrates. Possible therapeutic implications
-
Bisogno T., De Petrocellis L., Di Marzo V. Fatty acid amide hydrolase, an enzyme with many bioactive substrates. Possible therapeutic implications. Curr. Pharm. Des. 2002, 8:533-547.
-
(2002)
Curr. Pharm. Des.
, vol.8
, pp. 533-547
-
-
Bisogno, T.1
De Petrocellis, L.2
Di Marzo, V.3
-
7
-
-
22144477527
-
Anandamide induced PPARgamma transcriptional activation and 3T3-L1 preadipocyte differentiation
-
Bouaboula M., Hilairet S., Marchand J., Fajas L., Le Fur G., Casellas P. Anandamide induced PPARgamma transcriptional activation and 3T3-L1 preadipocyte differentiation. Eur. J. Pharmacol. 2005, 517:174-181.
-
(2005)
Eur. J. Pharmacol.
, vol.517
, pp. 174-181
-
-
Bouaboula, M.1
Hilairet, S.2
Marchand, J.3
Fajas, L.4
Le Fur, G.5
Casellas, P.6
-
8
-
-
35648944275
-
Alzheimer's disease; taking the edge off with cannabinoids?
-
Campbell V.A., Gowran A. Alzheimer's disease; taking the edge off with cannabinoids?. Br. J. Pharmacol. 2007, 152:655-662.
-
(2007)
Br. J. Pharmacol.
, vol.152
, pp. 655-662
-
-
Campbell, V.A.1
Gowran, A.2
-
9
-
-
79959772357
-
Human apoE isoforms differentially regulate brain amyloid-beta peptide clearance
-
Castellano J.M., Kim J., Stewart F.R., Jiang H., DeMattos R.B., Patterson B.W., Fagan A.M., Morris J.C., Mawuenyega K.G., Cruchaga C., Goate A.M., Bales K.R., Paul S.M., Bateman R.J., Holtzman D.M. Human apoE isoforms differentially regulate brain amyloid-beta peptide clearance. Sci. Transl. Med. 2011, 3:89ra57.
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Castellano, J.M.1
Kim, J.2
Stewart, F.R.3
Jiang, H.4
DeMattos, R.B.5
Patterson, B.W.6
Fagan, A.M.7
Morris, J.C.8
Mawuenyega, K.G.9
Cruchaga, C.10
Goate, A.M.11
Bales, K.R.12
Paul, S.M.13
Bateman, R.J.14
Holtzman, D.M.15
-
10
-
-
84870412999
-
Monoacylglycerol lipase is a therapeutic target for Alzheimer's disease
-
Chen R., Zhang J., Wu Y., Wang D., Feng G., Tang Y.P., Teng Z., Chen C. Monoacylglycerol lipase is a therapeutic target for Alzheimer's disease. Cell Rep. 2012, 2:1329-1339.
-
(2012)
Cell Rep.
, vol.2
, pp. 1329-1339
-
-
Chen, R.1
Zhang, J.2
Wu, Y.3
Wang, D.4
Feng, G.5
Tang, Y.P.6
Teng, Z.7
Chen, C.8
-
11
-
-
77951776829
-
Alzheimer's disease: strategies for disease modification
-
Citron M. Alzheimer's disease: strategies for disease modification. Nat. Rev. Drug Discov. 2010, 9:387-398.
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 387-398
-
-
Citron, M.1
-
12
-
-
48949117577
-
The role of the cell surface LRP and soluble LRP in blood-brain barrier Abeta clearance in Alzheimer's disease
-
Deane R., Sagare A., Zlokovic B.V. The role of the cell surface LRP and soluble LRP in blood-brain barrier Abeta clearance in Alzheimer's disease. Curr. Pharm. Des. 2008, 14:1601-1605.
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 1601-1605
-
-
Deane, R.1
Sagare, A.2
Zlokovic, B.V.3
-
13
-
-
0036678094
-
Brain monoglyceride lipase participating in endocannabinoid inactivation
-
Dinh T.P., Carpenter D., Leslie F.M., Freund T.F., Katona I., Sensi S.L., Kathuria S., Piomelli D. Brain monoglyceride lipase participating in endocannabinoid inactivation. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:10819-10824.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 10819-10824
-
-
Dinh, T.P.1
Carpenter, D.2
Leslie, F.M.3
Freund, T.F.4
Katona, I.5
Sensi, S.L.6
Kathuria, S.7
Piomelli, D.8
-
14
-
-
77951150250
-
Neuronal death in Alzheimer's disease and therapeutic opportunities
-
Donev R., Kolev M., Millet B., Thome J. Neuronal death in Alzheimer's disease and therapeutic opportunities. J. Cell. Mol. Med. 2009, 13:4329-4348.
-
(2009)
J. Cell. Mol. Med.
, vol.13
, pp. 4329-4348
-
-
Donev, R.1
Kolev, M.2
Millet, B.3
Thome, J.4
-
15
-
-
79960310251
-
Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-gamma
-
Du H., Chen X., Zhang J., Chen C. Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-gamma. Br. J. Pharmacol. 2011, 163:1533-1549.
-
(2011)
Br. J. Pharmacol.
, vol.163
, pp. 1533-1549
-
-
Du, H.1
Chen, X.2
Zhang, J.3
Chen, C.4
-
16
-
-
29244478635
-
Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation
-
Ehrhart J., Obregon D., Mori T., Hou H., Sun N., Bai Y., Klein T., Fernandez F., Tan J., Shytle R.D. Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation. J. Neuroinflammation 2005, 2:29.
-
(2005)
J. Neuroinflammation
, vol.2
, pp. 29
-
-
Ehrhart, J.1
Obregon, D.2
Mori, T.3
Hou, H.4
Sun, N.5
Bai, Y.6
Klein, T.7
Fernandez, F.8
Tan, J.9
Shytle, R.D.10
-
17
-
-
0023832275
-
Stimulation of lipolytic enzymes in Alzheimer's disease
-
Farooqui A.A., Liss L., Horrocks L.A. Stimulation of lipolytic enzymes in Alzheimer's disease. Ann. Neurol. 1988, 23:306-308.
-
(1988)
Ann. Neurol.
, vol.23
, pp. 306-308
-
-
Farooqui, A.A.1
Liss, L.2
Horrocks, L.A.3
-
18
-
-
77951689435
-
Biomarkers of oxidative damage and inflammation in Alzheimer's disease
-
Galasko D., Montine T.J. Biomarkers of oxidative damage and inflammation in Alzheimer's disease. Biomark. Med. 2010, 4:27-36.
-
(2010)
Biomark. Med.
, vol.4
, pp. 27-36
-
-
Galasko, D.1
Montine, T.J.2
-
19
-
-
0038823590
-
Adipocyte low density lipoprotein receptor-related protein gene expression and function is regulated by peroxisome proliferator-activated receptor gamma
-
Gauthier A., Vassiliou G., Benoist F., McPherson R. Adipocyte low density lipoprotein receptor-related protein gene expression and function is regulated by peroxisome proliferator-activated receptor gamma. J. Biol. Chem. 2003, 278:11945-11953.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 11945-11953
-
-
Gauthier, A.1
Vassiliou, G.2
Benoist, F.3
McPherson, R.4
-
20
-
-
13944262157
-
Endothelium-derived 2-arachidonylglycerol: an intermediate in vasodilatory eicosanoid release in bovine coronary arteries
-
Gauthier K.M., Baewer D.V., Hittner S., Hillard C.J., Nithipatikom K., Reddy D.S., Falck J.R., Campbell W.B. Endothelium-derived 2-arachidonylglycerol: an intermediate in vasodilatory eicosanoid release in bovine coronary arteries. Am. J. Physiol. Heart Circ. Physiol. 2005, 288:H1344-H1351.
-
(2005)
Am. J. Physiol. Heart Circ. Physiol.
, vol.288
-
-
Gauthier, K.M.1
Baewer, D.V.2
Hittner, S.3
Hillard, C.J.4
Nithipatikom, K.5
Reddy, D.S.6
Falck, J.R.7
Campbell, W.B.8
-
21
-
-
84862314657
-
Methylhonokiol attenuates neuroinflammation: a role for cannabinoid receptors?
-
Gertsch J., Anavi-Goffer S. Methylhonokiol attenuates neuroinflammation: a role for cannabinoid receptors?. J. Neuroinflammation 2012, 9:135.
-
(2012)
J. Neuroinflammation
, vol.9
, pp. 135
-
-
Gertsch, J.1
Anavi-Goffer, S.2
-
22
-
-
8844260491
-
Human brain endothelium: coexpression and function of vanilloid and endocannabinoid receptors
-
Golech S.A., McCarron R.M., Chen Y., Bembry J., Lenz F., Mechoulam R., Shohami E., Spatz M. Human brain endothelium: coexpression and function of vanilloid and endocannabinoid receptors. Brain Res. Mol. Brain Res. 2004, 132:87-92.
-
(2004)
Brain Res. Mol. Brain Res.
, vol.132
, pp. 87-92
-
-
Golech, S.A.1
McCarron, R.M.2
Chen, Y.3
Bembry, J.4
Lenz, F.5
Mechoulam, R.6
Shohami, E.7
Spatz, M.8
-
23
-
-
84859912791
-
CB1 cannabinoid receptor activation rescues amyloid beta-induced alterations in behaviour and intrinsic electrophysiological properties of rat hippocampal CA1 pyramidal neurones
-
Haghani M., Shabani M., Javan M., Motamedi F., Janahmadi M. CB1 cannabinoid receptor activation rescues amyloid beta-induced alterations in behaviour and intrinsic electrophysiological properties of rat hippocampal CA1 pyramidal neurones. Cell. Physiol. Biochem. 2012, 29:391-406.
-
(2012)
Cell. Physiol. Biochem.
, vol.29
, pp. 391-406
-
-
Haghani, M.1
Shabani, M.2
Javan, M.3
Motamedi, F.4
Janahmadi, M.5
-
24
-
-
84855998880
-
Contrasting protective effects of cannabinoids against oxidative stress and amyloid-beta evoked neurotoxicity in vitro
-
Harvey B.S., Ohlsson K.S., Maag J.L., Musgrave I.F., Smid S.D. Contrasting protective effects of cannabinoids against oxidative stress and amyloid-beta evoked neurotoxicity in vitro. Neurotoxicology 2012, 33:138-146.
-
(2012)
Neurotoxicology
, vol.33
, pp. 138-146
-
-
Harvey, B.S.1
Ohlsson, K.S.2
Maag, J.L.3
Musgrave, I.F.4
Smid, S.D.5
-
25
-
-
33847635165
-
Endothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerol
-
Ho W.S., Randall M.D. Endothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerol. Br. J. Pharmacol. 2007, 150:641-651.
-
(2007)
Br. J. Pharmacol.
, vol.150
, pp. 641-651
-
-
Ho, W.S.1
Randall, M.D.2
-
26
-
-
84859029863
-
A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury
-
Horvath B., Magid L., Mukhopadhyay P., Batkai S., Rajesh M., Park O., Tanchian G., Gao R.Y., Goodfellow C.E., Glass M., Mechoulam R., Pacher P. A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury. Br. J. Pharmacol. 2012, 165:2462-2478.
-
(2012)
Br. J. Pharmacol.
, vol.165
, pp. 2462-2478
-
-
Horvath, B.1
Magid, L.2
Mukhopadhyay, P.3
Batkai, S.4
Rajesh, M.5
Park, O.6
Tanchian, G.7
Gao, R.Y.8
Goodfellow, C.E.9
Glass, M.10
Mechoulam, R.11
Pacher, P.12
-
27
-
-
27644433182
-
Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects
-
Jiang W., Zhang Y., Xiao L., Van Cleemput J., Ji S.P., Bai G., Zhang X. Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects. J. Clin. Invest. 2005, 115:3104-3116.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 3104-3116
-
-
Jiang, W.1
Zhang, Y.2
Xiao, L.3
Van Cleemput, J.4
Ji, S.P.5
Bai, G.6
Zhang, X.7
-
28
-
-
3342979420
-
Defective adult neurogenesis in CB1 cannabinoid receptor knockout mice
-
Jin K., Xie L., Kim S.H., Parmentier-Batteur S., Sun Y., Mao X.O., Childs J., Greenberg D.A. Defective adult neurogenesis in CB1 cannabinoid receptor knockout mice. Mol. Pharmacol. 2004, 66:204-208.
-
(2004)
Mol. Pharmacol.
, vol.66
, pp. 204-208
-
-
Jin, K.1
Xie, L.2
Kim, S.H.3
Parmentier-Batteur, S.4
Sun, Y.5
Mao, X.O.6
Childs, J.7
Greenberg, D.A.8
-
29
-
-
84858984433
-
CB1 receptor antagonists: new discoveries leading to new perspectives
-
Kirilly E., Gonda X., Bagdy G. CB1 receptor antagonists: new discoveries leading to new perspectives. Acta Physiol. (Oxf.) 2012, 205:41-60.
-
(2012)
Acta Physiol. (Oxf.)
, vol.205
, pp. 41-60
-
-
Kirilly, E.1
Gonda, X.2
Bagdy, G.3
-
30
-
-
80053387416
-
Cerebral amyloid-beta proteostasis is regulated by the membrane transport protein ABCC1 in mice
-
Krohn M., Lange C., Hofrichter J., Scheffler K., Stenzel J., Steffen J., Schumacher T., Bruning T., Plath A.S., Alfen F., Schmidt A., Winter F., Rateitschak K., Wree A., Gsponer J., Walker L.C., Pahnke J. Cerebral amyloid-beta proteostasis is regulated by the membrane transport protein ABCC1 in mice. J. Clin. Invest. 2011, 121:3924-3931.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 3924-3931
-
-
Krohn, M.1
Lange, C.2
Hofrichter, J.3
Scheffler, K.4
Stenzel, J.5
Steffen, J.6
Schumacher, T.7
Bruning, T.8
Plath, A.S.9
Alfen, F.10
Schmidt, A.11
Winter, F.12
Rateitschak, K.13
Wree, A.14
Gsponer, J.15
Walker, L.C.16
Pahnke, J.17
-
31
-
-
0036830947
-
Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
-
LaFerla F.M. Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease. Nat. Rev. Neurosci. 2002, 3:862-872.
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, pp. 862-872
-
-
LaFerla, F.M.1
-
32
-
-
34250819839
-
Intracellular amyloid-beta in Alzheimer's disease
-
LaFerla F.M., Green K.N., Oddo S. Intracellular amyloid-beta in Alzheimer's disease. Nat. Rev. Neurosci. 2007, 8:499-509.
-
(2007)
Nat. Rev. Neurosci.
, vol.8
, pp. 499-509
-
-
LaFerla, F.M.1
Green, K.N.2
Oddo, S.3
-
33
-
-
57749087828
-
Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects
-
Long J.Z., Li W., Booker L., Burston J.J., Kinsey S.G., Schlosburg J.E., Pavon F.J., Serrano A.M., Selley D.E., Parsons L.H., Lichtman A.H., Cravatt B.F. Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. Nat. Chem. Biol. 2009, 5:37-44.
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 37-44
-
-
Long, J.Z.1
Li, W.2
Booker, L.3
Burston, J.J.4
Kinsey, S.G.5
Schlosburg, J.E.6
Pavon, F.J.7
Serrano, A.M.8
Selley, D.E.9
Parsons, L.H.10
Lichtman, A.H.11
Cravatt, B.F.12
-
34
-
-
73949109254
-
Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo
-
Long J.Z., Nomura D.K., Vann R.E., Walentiny D.M., Booker L., Jin X., Burston J.J., Sim-Selley L.J., Lichtman A.H., Wiley J.L., Cravatt B.F. Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:20270-20275.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 20270-20275
-
-
Long, J.Z.1
Nomura, D.K.2
Vann, R.E.3
Walentiny, D.M.4
Booker, L.5
Jin, X.6
Burston, J.J.7
Sim-Selley, L.J.8
Lichtman, A.H.9
Wiley, J.L.10
Cravatt, B.F.11
-
35
-
-
33645537283
-
Regulation by cannabinoid receptors of anandamide transport across the blood-brain barrier and through other endothelial cells
-
Maccarrone M., Fiori A., Bari M., Granata F., Gasperi V., De Stefano M.E., Finazzi-Agro A., Strom R. Regulation by cannabinoid receptors of anandamide transport across the blood-brain barrier and through other endothelial cells. Thromb. Haemost. 2006, 95:117-127.
-
(2006)
Thromb. Haemost.
, vol.95
, pp. 117-127
-
-
Maccarrone, M.1
Fiori, A.2
Bari, M.3
Granata, F.4
Gasperi, V.5
De Stefano, M.E.6
Finazzi-Agro, A.7
Strom, R.8
-
36
-
-
84855813696
-
Can the benefits of cannabinoid receptor stimulation on neuroinflammation, neurogenesis and memory during normal aging be useful in AD prevention?
-
Marchalant Y., Baranger K., Wenk G.L., Khrestchatisky M., Rivera S. Can the benefits of cannabinoid receptor stimulation on neuroinflammation, neurogenesis and memory during normal aging be useful in AD prevention?. J. Neuroinflammation 2012, 9:10.
-
(2012)
J. Neuroinflammation
, vol.9
, pp. 10
-
-
Marchalant, Y.1
Baranger, K.2
Wenk, G.L.3
Khrestchatisky, M.4
Rivera, S.5
-
37
-
-
77955053537
-
The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors
-
Marrs W.R., Blankman J.L., Horne E.A., Thomazeau A., Lin Y.H., Coy J., Bodor A.L., Muccioli G.G., Hu S.S., Woodruff G., Fung S., Lafourcade M., Alexander J.P., Long J.Z., Li W., Xu C., Moller T., Mackie K., Manzoni O.J., Cravatt B.F., Stella N. The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. Nat. Neurosci. 2010, 13:951-957.
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 951-957
-
-
Marrs, W.R.1
Blankman, J.L.2
Horne, E.A.3
Thomazeau, A.4
Lin, Y.H.5
Coy, J.6
Bodor, A.L.7
Muccioli, G.G.8
Hu, S.S.9
Woodruff, G.10
Fung, S.11
Lafourcade, M.12
Alexander, J.P.13
Long, J.Z.14
Li, W.15
Xu, C.16
Moller, T.17
Mackie, K.18
Manzoni, O.J.19
Cravatt, B.F.20
Stella, N.21
more..
-
38
-
-
0141865717
-
CB1 cannabinoid receptors and on-demand defense against excitotoxicity
-
Marsicano G., Goodenough S., Monory K., Hermann H., Eder M., Cannich A., Azad S.C., Cascio M.G., Gutierrez S.O., Van der Stelt M., Lopez-Rodriguez M.L., Casanova E., Schutz G., Zieglgansberger W., Di Marzo V., Behl C., Lutz B. CB1 cannabinoid receptors and on-demand defense against excitotoxicity. Science 2003, 302:84-88.
-
(2003)
Science
, vol.302
, pp. 84-88
-
-
Marsicano, G.1
Goodenough, S.2
Monory, K.3
Hermann, H.4
Eder, M.5
Cannich, A.6
Azad, S.C.7
Cascio, M.G.8
Gutierrez, S.O.9
Van der Stelt, M.10
Lopez-Rodriguez, M.L.11
Casanova, E.12
Schutz, G.13
Zieglgansberger, W.14
Di Marzo, V.15
Behl, C.16
Lutz, B.17
-
39
-
-
84855812968
-
Prolonged oral cannabinoid administration prevents neuroinflammation, lowers beta-amyloid levels and improves cognitive performance in Tg APP 2576 mice
-
Martin-Moreno A.M., Brera B., Spuch C., Carro E., Garcia-Garcia L., Delgado M., Pozo M.A., Innamorato N.G., Cuadrado A., de Ceballos M.L. Prolonged oral cannabinoid administration prevents neuroinflammation, lowers beta-amyloid levels and improves cognitive performance in Tg APP 2576 mice. J. Neuroinflammation 2012, 9:8.
-
(2012)
J. Neuroinflammation
, vol.9
, pp. 8
-
-
Martin-Moreno, A.M.1
Brera, B.2
Spuch, C.3
Carro, E.4
Garcia-Garcia, L.5
Delgado, M.6
Pozo, M.A.7
Innamorato, N.G.8
Cuadrado, A.9
de Ceballos, M.L.10
-
40
-
-
78650678688
-
Decreased clearance of CNS beta-amyloid in Alzheimer's disease
-
Mawuenyega K.G., Sigurdson W., Ovod V., Munsell L., Kasten T., Morris J.C., Yarasheski K.E., Bateman R.J. Decreased clearance of CNS beta-amyloid in Alzheimer's disease. Science 2010, 330:1774.
-
(2010)
Science
, vol.330
, pp. 1774
-
-
Mawuenyega, K.G.1
Sigurdson, W.2
Ovod, V.3
Munsell, L.4
Kasten, T.5
Morris, J.C.6
Yarasheski, K.E.7
Bateman, R.J.8
-
41
-
-
0032590054
-
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
-
McLean C.A., Cherny R.A., Fraser F.W., Fuller S.J., Smith M.J., Beyreuther K., Bush A.I., Masters C.L. Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann. Neurol. 1999, 46:860-866.
-
(1999)
Ann. Neurol.
, vol.46
, pp. 860-866
-
-
McLean, C.A.1
Cherny, R.A.2
Fraser, F.W.3
Fuller, S.J.4
Smith, M.J.5
Beyreuther, K.6
Bush, A.I.7
Masters, C.L.8
-
42
-
-
34548703093
-
Amyloid beta protein as a marker or risk factor of Alzheimer's disease
-
Mehta P.D. Amyloid beta protein as a marker or risk factor of Alzheimer's disease. Curr. Alzheimer Res. 2007, 4:359-363.
-
(2007)
Curr. Alzheimer Res.
, vol.4
, pp. 359-363
-
-
Mehta, P.D.1
-
43
-
-
0037206662
-
Anandamide and noladin ether prevent neurotoxicity of the human amyloid-beta peptide
-
Milton N.G. Anandamide and noladin ether prevent neurotoxicity of the human amyloid-beta peptide. Neurosci. Lett. 2002, 332:127-130.
-
(2002)
Neurosci. Lett.
, vol.332
, pp. 127-130
-
-
Milton, N.G.1
-
44
-
-
81055156684
-
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation
-
Nomura D.K., Morrison B.E., Blankman J.L., Long J.Z., Kinsey S.G., Marcondes M.C., Ward A.M., Hahn Y.K., Lichtman A.H., Conti B., Cravatt B.F. Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation. Science 2011, 334:809-813.
-
(2011)
Science
, vol.334
, pp. 809-813
-
-
Nomura, D.K.1
Morrison, B.E.2
Blankman, J.L.3
Long, J.Z.4
Kinsey, S.G.5
Marcondes, M.C.6
Ward, A.M.7
Hahn, Y.K.8
Lichtman, A.H.9
Conti, B.10
Cravatt, B.F.11
-
45
-
-
43849095304
-
Amyloid imaging in Alzheimer's disease
-
Nordberg A. Amyloid imaging in Alzheimer's disease. Neuropsychologia 2008, 46:1636-1641.
-
(2008)
Neuropsychologia
, vol.46
, pp. 1636-1641
-
-
Nordberg, A.1
-
46
-
-
35649008926
-
Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors
-
O'Sullivan S.E. Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors. Br. J. Pharmacol. 2007, 152:576-582.
-
(2007)
Br. J. Pharmacol.
, vol.152
, pp. 576-582
-
-
O'Sullivan, S.E.1
-
47
-
-
80053024234
-
Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice
-
Pan B., Wang W., Zhong P., Blankman J.L., Cravatt B.F., Liu Q.S. Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice. J. Neurosci. 2011, 31:13420-13430.
-
(2011)
J. Neurosci.
, vol.31
, pp. 13420-13430
-
-
Pan, B.1
Wang, W.2
Zhong, P.3
Blankman, J.L.4
Cravatt, B.F.5
Liu, Q.S.6
-
48
-
-
79952860789
-
Selective antihypertensive dihydropyridines lower abeta accumulation by targeting both the production and the clearance of abeta across the blood-brain barrier
-
Paris D., Bachmeier C., Patel N., Quadros A., Volmar C.H., Laporte V., Ganey J., Beaulieu-Abdelahad D., Ait-Ghezala G., Crawford F., Mullan M.J. Selective antihypertensive dihydropyridines lower abeta accumulation by targeting both the production and the clearance of abeta across the blood-brain barrier. Mol. Med. 2011, 17:149-162.
-
(2011)
Mol. Med.
, vol.17
, pp. 149-162
-
-
Paris, D.1
Bachmeier, C.2
Patel, N.3
Quadros, A.4
Volmar, C.H.5
Laporte, V.6
Ganey, J.7
Beaulieu-Abdelahad, D.8
Ait-Ghezala, G.9
Crawford, F.10
Mullan, M.J.11
-
49
-
-
84863103124
-
A dysregulated endocannabinoid-eicosanoid network supports pathogenesis in a mouse model of Alzheimer's disease
-
Piro J.R., Benjamin D.I., Duerr J.M., Pi Y., Gonzales C., Wood K.M., Schwartz J.W., Nomura D.K., Samad T.A. A dysregulated endocannabinoid-eicosanoid network supports pathogenesis in a mouse model of Alzheimer's disease. Cell Rep. 2012, 1:617-623.
-
(2012)
Cell Rep.
, vol.1
, pp. 617-623
-
-
Piro, J.R.1
Benjamin, D.I.2
Duerr, J.M.3
Pi, Y.4
Gonzales, C.5
Wood, K.M.6
Schwartz, J.W.7
Nomura, D.K.8
Samad, T.A.9
-
50
-
-
33745280979
-
Interleukin-2 suppression by 2-arachidonyl glycerol is mediated through peroxisome proliferator-activated receptor gamma independently of cannabinoid receptors 1 and 2
-
Rockwell C.E., Snider N.T., Thompson J.T., Vanden Heuvel J.P., Kaminski N.E. Interleukin-2 suppression by 2-arachidonyl glycerol is mediated through peroxisome proliferator-activated receptor gamma independently of cannabinoid receptors 1 and 2. Mol. Pharmacol. 2006, 70:101-111.
-
(2006)
Mol. Pharmacol.
, vol.70
, pp. 101-111
-
-
Rockwell, C.E.1
Snider, N.T.2
Thompson, J.T.3
Vanden Heuvel, J.P.4
Kaminski, N.E.5
-
51
-
-
34948888151
-
Clearance of amyloid-beta by circulating lipoprotein receptors
-
Sagare A., Deane R., Bell R.D., Johnson B., Hamm K., Pendu R., Marky A., Lenting P.J., Wu Z., Zarcone T., Goate A., Mayo K., Perlmutter D., Coma M., Zhong Z., Zlokovic B.V. Clearance of amyloid-beta by circulating lipoprotein receptors. Nat. Med. 2007, 13:1029-1031.
-
(2007)
Nat. Med.
, vol.13
, pp. 1029-1031
-
-
Sagare, A.1
Deane, R.2
Bell, R.D.3
Johnson, B.4
Hamm, K.5
Pendu, R.6
Marky, A.7
Lenting, P.J.8
Wu, Z.9
Zarcone, T.10
Goate, A.11
Mayo, K.12
Perlmutter, D.13
Coma, M.14
Zhong, Z.15
Zlokovic, B.V.16
-
53
-
-
84855359304
-
The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors
-
Savinainen J.R., Saario S.M., Laitinen J.T. The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors. Acta Physiol. (Oxf.) 2012, 204:267-276.
-
(2012)
Acta Physiol. (Oxf.)
, vol.204
, pp. 267-276
-
-
Savinainen, J.R.1
Saario, S.M.2
Laitinen, J.T.3
-
54
-
-
77952651099
-
The endocannabinoid system as a target for the treatment of neurodegenerative disease
-
Scotter E.L., Abood M.E., Glass M. The endocannabinoid system as a target for the treatment of neurodegenerative disease. Br. J. Pharmacol. 2010, 160:480-498.
-
(2010)
Br. J. Pharmacol.
, vol.160
, pp. 480-498
-
-
Scotter, E.L.1
Abood, M.E.2
Glass, M.3
-
55
-
-
0031706164
-
Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity
-
Shen M., Thayer S.A. Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity. Mol. Pharmacol. 1998, 54:459-462.
-
(1998)
Mol. Pharmacol.
, vol.54
, pp. 459-462
-
-
Shen, M.1
Thayer, S.A.2
-
56
-
-
0034521392
-
Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier
-
Shibata M., Yamada S., Kumar S.R., Calero M., Bading J., Frangione B., Holtzman D.M., Miller C.A., Strickland D.K., Ghiso J., Zlokovic B.V. Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. J. Clin. Invest. 2000, 106:1489-1499.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 1489-1499
-
-
Shibata, M.1
Yamada, S.2
Kumar, S.R.3
Calero, M.4
Bading, J.5
Frangione, B.6
Holtzman, D.M.7
Miller, C.A.8
Strickland, D.K.9
Ghiso, J.10
Zlokovic, B.V.11
-
57
-
-
33745195042
-
Biochemistry, pharmacology and physiology of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand
-
Sugiura T., Kishimoto S., Oka S., Gokoh M. Biochemistry, pharmacology and physiology of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand. Prog. Lipid Res. 2006, 45:405-446.
-
(2006)
Prog. Lipid Res.
, vol.45
, pp. 405-446
-
-
Sugiura, T.1
Kishimoto, S.2
Oka, S.3
Gokoh, M.4
-
58
-
-
33745327044
-
Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels
-
Van der Stelt M., Mazzola C., Esposito G., Matias I., Petrosino S., De Filippis D., Micale V., Steardo L., Drago F., Iuvone T., Di Marzo V. Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels. Cell. Mol. Life Sci. 2006, 63:1410-1424.
-
(2006)
Cell. Mol. Life Sci.
, vol.63
, pp. 1410-1424
-
-
Van der Stelt, M.1
Mazzola, C.2
Esposito, G.3
Matias, I.4
Petrosino, S.5
De Filippis, D.6
Micale, V.7
Steardo, L.8
Drago, F.9
Iuvone, T.10
Di Marzo, V.11
-
59
-
-
67349118757
-
Microvasculature changes and cerebral amyloid angiopathy in Alzheimer's disease and their potential impact on therapy
-
Weller R.O., Boche D., Nicoll J.A. Microvasculature changes and cerebral amyloid angiopathy in Alzheimer's disease and their potential impact on therapy. Acta Neuropathol. 2009, 118:87-102.
-
(2009)
Acta Neuropathol.
, vol.118
, pp. 87-102
-
-
Weller, R.O.1
Boche, D.2
Nicoll, J.A.3
-
60
-
-
84870489074
-
Activation of the CB(2) receptor system reverses amyloid-induced memory deficiency
-
Wu J., Bie B., Yang H., Xu J.J., Brown D.L., Naguib M. Activation of the CB(2) receptor system reverses amyloid-induced memory deficiency. Neurobiol. Aging 2013, 34:791-804.
-
(2013)
Neurobiol. Aging
, vol.34
, pp. 791-804
-
-
Wu, J.1
Bie, B.2
Yang, H.3
Xu, J.J.4
Brown, D.L.5
Naguib, M.6
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