Interaction of PICK1 with C-Terminus of Growth Hormone-Releasing Hormone Receptor (GHRHR) modulates trafficking and signal transduction of human GHRHR

Journal of Pharmacological Sciences

Volumn 122, Issue 3, 2013, Pages 193-204

  Katsushima, Yuriko ^a   Sato, Takeya ^a   Yamada, Chika ^a   Ito, Moe ^a   Suzuki, Yuki ^a   Ogawa, Eishin ^a   Sukegawa, Izumi ^a   Sukegawa, Jun ^a   Fukunaga, Kohji ^b   Yanagisawa, Teruyuki ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

Growth hormone releasing hormone receptor (GHRHR); Interaction; Protein interacting with C kinase 1 (PICK1); Signaling; Trafficking

Indexed keywords

AMINO ACID; G PROTEIN COUPLED RECEPTOR; GROWTH HORMONE RELEASING FACTOR; GROWTH HORMONE RELEASING FACTOR RECEPTOR; PROTEIN INTERACTING WITH PROTEIN KINASE C;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING ASSAY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GROWTH HORMONE RELEASE; GROWTH HORMONE SECRETING CELL; HORMONE BINDING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PDZ DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION;

ANIMALS; BRAIN; CARRIER PROTEINS; GROWTH HORMONE-RELEASING HORMONE; HUMANS; MALE; NUCLEAR PROTEINS; PDZ DOMAINS; PROTEIN BINDING; PROTEIN TRANSPORT; RATS, SPRAGUE-DAWLEY; RECEPTORS, PITUITARY HORMONE-REGULATING HORMONE; SIGNAL TRANSDUCTION;

EID: 84880818779     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.12287FP     Document Type: Article

References (51)

1. Takeda S, Kadowaki S, Haga T, Takaesu H, Mitaku S. Identification of G protein-coupled receptor genes from the human genome sequence. FEBS Lett. 2002;520:97-101.
2. Fredriksson R, Lagerstrom MC, Lundin LG, Schioth HB. The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol. 2003;63:1256-1272.
3. Bockaert J, Marin P, Dumuis A, Fagni L. The 'magic tail' of G protein-coupled receptors: an anchorage for functional protein networks. FEBS Lett. 2003;546:65-72.
4. Sugai M, Saito M, Sukegawa I, Katsushima Y, Kinouchi Y, Nakahata N, et al. PTH/PTH-related protein receptor interacts directly with Tctex-1 through its COOH terminus. Biochem Biophys Res Commun. 2003;311:24-31.
5. Saito M, Sugai M, Katsushima Y, Yanagisawa T, Sukegawa J, Nakahata N. Increase in cell-surface localization of parathyroid hormone receptor by cytoskeletal protein 4.1G. Biochem J. 2005;392:75-81.
6. Maeda K, Haraguchi M, Kuramasu A, Sato T, Ariake K, Sakagami H, et al. CLIC4 interacts with histamine H3 receptor and enhances the receptor cell surface expression. Biochem Biophys Res Commun. 2008;369:603-608.
7. Cardoso JC, Vieira FA, Gomes AS, Power DM. The serendipitous origin of chordate secretin peptide family members. BMC Evol Biol. 2010;10:135.
8. Vohra S, Chintapalli SV, Illingworth CJ, Reeves PJ, Mullineaux PM, Clark HS, et al. Computational studies of Family A and Family B GPCRs. Biochem Soc Trans. 2007;35:749-754.
9. Gaylinn BD, Harrison JK, Zysk JR, Lyons CE, Lynch KR, Thorner MO. Molecular cloning and expression of a human anterior pituitary receptor for growth hormone-releasing hormone. Mol Endocrinol. 1993;7:77-84.
10. Mayo KE, Godfrey PA, Suhr ST, Kulik DJ, Rahal JO. Growth hormone-releasing hormone: synthesis and signaling. Recent Prog Horm Res. 1995;50:35-73.
11. Rekasi Z, Czompoly T, Schally AV, Halmos G. Isolation and sequencing of cDNAs for splice variants of growth hormone-releasing hormone receptors from human cancers. Proc Natl Acad Sci U S A. 2000;97:10561-10566.
12. Havt A, Schally AV, Halmos G, Varga JL, Toller GL, Horvath JE, et al. The expression of the pituitary growth hormone-releasing hormone receptor and its splice variants in normal and neoplastic human tissues. Proc Natl Acad Sci U S A. 2005;102:17424-17429.
13. Granata R, Trovato L, Gallo MP, Destefanis S, Settanni F, Scarlatti F, et al. Growth hormone-releasing hormone promotes survival of cardiac myocytes in vitro and protects against ischaemia-reperfusion injury in rat heart. Cardiovasc Res. 2009; 83:303-312.
14. Kanashiro-Takeuchi RM, Tziomalos K, Takeuchi LM, Treuer AV, Lamirault G, Dulce R, et al. Cardioprotective effects of growth hormone-releasing hormone agonist after myocardial infarction. Proc Natl Acad Sci U S A. 2010;107:2604-2609.
15. Kahan Z, Arencibia JM, Csernus VJ, Groot K, Kineman RD, Robinson WR, et al. Expression of growth hormone-releasing hormone (GHRH) messenger ribonucleic acid and the presence of biologically active GHRH in human breast, endometrial, and ovarian cancers. J Clin Endocrinol Metab. 1999;84:582-589.
16. Ludwig B, Ziegler CG, Schally AV, Richter C, Steffen A, Jabs N, et al. Agonist of growth hormone-releasing hormone as a potential effector for survival and proliferation of pancreatic islets. Proc Natl Acad Sci U S A. 2010;107:12623-12628.
17. Dioufa N, Schally AV, Chatzistamou I, Moustou E, Block NL, Owens GK, et al. Acceleration of wound healing by growth hormone-releasing hormone and its agonists. Proc Natl Acad Sci U S A. 2010;107:18611-18615.
18. Bockaert J, Fagni L, Dumuis A, Marin P. GPCR interacting proteins (GIP). Pharmacol Ther. 2004;103:203-221.
19. Maurice P, Guillaume JL, Benleulmi-Chaachoua A, Daulat AM, Kamal M, Jockers R. GPCR-interacting proteins, major players of GPCR function. Adv Pharmacol. 2011;62:349-380.
20. Magalhaes AC, Dunn H, Ferguson SS. Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins. Br J Pharmacol. 2012;165:1717-1736.
21. Scaife M, Pacienza N, Au BC, Wang JC, Devine S, Scheid E, et al. Engineered human Tmpk fused with truncated cell-surface markers: versatile cell-fate control safety cassettes. Gene Ther. 2013;20:24-34.
22. Sato T, Neschadim A, Konrad M, Fowler DH, Lavie A, Medin JA. Engineered human tmpk/AZT as a novel enzyme/prodrug axis for suicide gene therapy. Mol Ther. 2007;15:962-970.
23. Jin W, Shen C, Jing L, Zha XM, Xia J. PICK1 regulates the trafficking of ASIC1a and acidotoxicity in a BAR domain lipid binding-dependent manner. Mol Brain. 2010;3:39.
24. Songyang Z, Fanning AS, Fu C, Xu J, Marfatia SM, Chishti AH, et al. Recognition of unique carboxyl-terminal motifs by distinct PDZ domains. Science. 1997;275:73-77.
25. Nourry C, Grant SG, Borg JP. PDZ domain proteins: plug and play! Sci STKE. 2003;2003:RE7.
26. Stricker NL, Christopherson KS, Yi BA, Schatz PJ, Raab RW, Dawes G, et al. PDZ domain of neuronal nitric oxide synthase recognizes novel C-terminal peptide sequences. Nat Biotechnol. 1997;15:336-342.
27. Lin SH, Arai AC, Wang Z, Nothacker HP, Civelli O. The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering. Mol Pharmacol. 2001;60:916-923.
28. Peter BJ, Kent HM, Mills IG, Vallis Y, Butler PJ, Evans PR, et al. BAR domains as sensors of membrane curvature: the amphiphysin BAR structure. Science. 2004;303:495-499.
29. Staudinger J, Lu J, Olson EN. Specific interaction of the PDZ domain protein PICK1 with the COOH terminus of protein kinase C-alpha. J Biol Chem. 1997;272:32019-32024.
30. Xia J, Zhang X, Staudinger J, Huganir RL. Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1. Neuron. 1999;22:179-187.
31. Torres GE, Yao WD, Mohn AR, Quan H, Kim KM, Levey AI, et al. Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1. Neuron. 2001;30:121-134.
32. Stangelberger A, Schally AV, Varga JL, Zarandi M, Cai RZ, Baker B, et al. Inhibition of human androgen-independent PC-3 and DU-145 prostate cancers by antagonists of bombesin and growth hormone releasing hormone is linked to PKC, MAPK and c-jun intracellular signalling. Eur J Cancer. 2005;41: 2735-2744.
33. Duggan A, Garcia-Anoveros J, Corey DP. The PDZ domain protein PICK1 and the sodium channel BNaC1 interact and localize at mechanosensory terminals of dorsal root ganglion neurons and dendrites of central neurons. J Biol Chem. 2002; 277:5203-5208.
34. + channel 1) and ASIC (acid-sensing ion channel). Biochem J. 2002;361:443-450.
35. Vance ML, Kaiser DL, Evans WS, Thorner MO, Furlanetto R, Rivier J, et al. Evidence for a limited growth hormone (GH)-releasing hormone (GHRH)-releasable quantity of GH: effects of 6-hour infusions of GHRH on GH secretion in normal man. J Clin Endocrinol Metab. 1985;60:370-375.
36. Ceda GP, Hoffman AR. Growth hormone-releasing factor desensitization in rat anterior pituitary cells in vitro. Endocrinology. 1985;116:1334-1340.
37. Davis JR, Sheppard MC, Shakespear RA, Lynch SS, Clayton RN. Does growth hormone releasing factor desensitize the somatotroph? Interpretation of responses of growth hormone during and after 10-hour infusion of GRF 1-29 amide in man. Clin Endocrinol (Oxf). 1986;24:135-140.
38. Veyrat-Durebex C, Pomerleau L, Langlois D, Gaudreau P. Internalization and trafficking of the human and rat growth hormone-releasing hormone receptor. J Cell Physiol. 2005;203: 335-344.
39. Madsen KL, Thorsen TS, Rahbek-Clemmensen T, Eriksen J, Gether U. Protein interacting with C kinase 1 (PICK1) reduces reinsertion rates of interaction partners sorted to Rab11-dependent slow recycling pathway. J Biol Chem. 2012;287: 12293-12308.
40. Volk L, Kim CH, Takamiya K, Yu Y, Huganir RL. Developmental regulation of protein interacting with C kinase 1 (PICK1) function in hippocampal synaptic plasticity and learning. Proc Natl Acad Sci U S A. 2010;107:21784-21789.
41. Estall JL, Koehler JA, Yusta B, Drucker DJ. The glucagon-like peptide-2 receptor C terminus modulates beta-arrestin-2 association but is dispensable for ligand-induced desensitization, endocytosis, and G-protein-dependent effector activation. J Biol Chem. 2005;280:22124-22134.
42. Unson CG, Cypess AM, Kim HN, Goldsmith PK, Carruthers CJ, Merrifield RB, et al. Characterization of deletion and truncation mutants of the rat glucagon receptor. Seven transmembrane segments are necessary for receptor transport to the plasma membrane and glucagon binding. J Biol Chem. 1995;270: 27720-27727.
43. Horikawa R, Gaylinn BD, Lyons CE Jr, Thorner MO. Molecular cloning of ovine and bovine growth hormone-releasing hormone receptors: the ovine receptor is C-terminally truncated. Endocrinology. 2001;142:2660-2668.
44. Pitcher JA, Freedman NJ, Lefkowitz RJ. G protein-coupled receptor kinases. Annu Rev Biochem. 1998;67:653-692.
45. Luttrell LM, Lefkowitz RJ. The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. J Cell Sci. 2002;115:455-465.
46. Bouvier M, Hausdorff WP, De Blasi A, O'Dowd BF, Kobilka BK, Caron MG, et al. Removal of phosphorylation sites from the beta 2-adrenergic receptor delays onset of agonist-promoted desensitization. Nature. 1988;333:370-373.
47. Luttrell LM, Ferguson SS, Daaka Y, Miller WE, Maudsley S, Della Rocca GJ, et al. Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science. 1999;283:655-661.
48. Lefkowitz RJ, Shenoy SK. Transduction of receptor signals by beta-arrestins. Science. 2005;308:512-517.
49. Imamura T, Huang J, Dalle S, Ugi S, Usui I, Luttrell LM, et al. beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport. J Biol Chem. 2001;276:43663-43667.
50. Gong K, Li Z, Xu M, Du J, Lv Z, Zhang Y. A novel protein kinase A-independent, beta-arrestin-1-dependent signaling pathway for p38 mitogen-activated protein kinase activation by beta2-adrenergic receptors. J Biol Chem. 2008;283:29028-29036.
51. McDonald PH, Chow CW, Miller WE, Laporte SA, Field ME, Lin FT, et al. Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3. Science. 2000;290:1574-1577.