Shifts in the Distribution of Mass Densities Is a Signature of Caloric Restriction in Caenorhabditis elegans

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Reina, Alfonso ^a   Subramaniam, Anand Bala ^a   Laromaine, Anna ^a,c   Samuel, Aravinthan D T ^b   Whitesides, George M ^a  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

^c INSTITUT DE CIÈNCIA DE MATERIALS DE BARCELONA ICMAB CSIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN; IVERMECTIN;

ADULTHOOD; ARTICLE; CAENORHABDITIS ELEGANS; CALORIC RESTRICTION; CONTROLLED STUDY; CULTURE MEDIUM; FOOD DEPRIVATION; LARVAL STAGE; NONHUMAN; POPULATION DENSITY; POPULATION DISTRIBUTION; STARVATION; WILD TYPE;

ANIMALS; CAENORHABDITIS ELEGANS; FOOD DEPRIVATION; IVERMECTIN; LARVA;

EID: 84880817406     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0069651     Document Type: Article

References (44)

1. Brenner S, (1974) Genetics of Caenorhabditis elegans. Genetics 77: 71-94.
2. Avery L, (1993) The genetics of feeding in Caenorhabditis elegans. Genetics 133: 897-917.
3. Hulme SE, Whitesides GM, (2011) Chemistry and the Worm: Caenorhabditis elegans as a platform for integrating chemical and biological research. Angew Chem Int Ed 50: 4774-4807.
4. Van Voorhies WA, Ward S, (1999) Genetic and environmental conditions that increase longevity in Caenorhabditis elegans decrease metabolic rate. Proc Natl Acad Sci USA 96: 11399-11403.
5. Lakowski B, Hekimi S, (1998) The genetics of caloric restriction in Caenorhabditis elegans. Proc Natl Acad Sci USA 95: 13091-13096.
6. Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, et al. (1997) The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389: 994-999.
7. Kenyon C, (2005) The plasticity of aging: Insights from long-lived mutants. Cell 120: 449-460.
8. Wang MC, O'Rourke EJ, Ruvkun G, (2008) Fat metabolism links germline stem cells and longevity in C. elegans. Science 322: 957-960.
9. Cooper AF, Vangundy SD, (1970) Metabolism of glycogen and neutral lipids by Aphelenchus avenae and Caenorhabditis sp. in aerobic, microaerobic, and anaerobic environments. J Nematol 2: 305-315.
10. Tan KT, Luo SC, Ho WZ, Lee YH, (2011) Insulin/IGF-1 Receptor signaling enhances biosynthetic activity and fat mobilization in the initial phase of starvation in adult male C. elegans. Cell Metab 14: 390-402.
11. Kimura KD, Tissenbaum HA, Liu YX, Ruvkun G, (1997) daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277: 942-946.
12. Ashrafi K, Chang FY, Watts JL, Fraser AG, Kamath RS, et al. (2003) Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 421: 268-272.
13. Zarse K, Ristow M, (2008) Antidepressants of the serotonin-antagonist type increase body fat and decrease lifespan of adult Caenorhabditis elegans. PLoS One 3.
14. Petrascheck M, Ye XL, Buck LB, (2007) An antidepressant that extends lifespan in adult Caenorhabditis elegans. Nature 450: 553-U512.
15. Derry WB, Putzke AP, Rothman JH, (2001) Caenorhabditis elegans p53: Role in apoptosis, meiosis, and stress resistance. Science 294: 591-595.
16. Lee I, Hendrix A, Kim J, Yoshimoto J, You YJ, (2012) Metabolic rate regulates L1 longevity in C. elegans. PLoS One 7.
17. Lucanic M, Held JM, Vantipalli MC, Klang IM, Graham JB, et al. (2011) N-acylethanolamine signalling mediates the effect of diet on lifespan in Caenorhabditis elegans. Nature 473: 226-229.
18. Narbonne P, Roy R, (2009) Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival. Nature 457: 210-U108.
19. Lamitina ST, Morrison R, Moeckel GW, Strange K, (2004) Adaptation of the nematode Caenorhabditis elegans to extreme osmotic stress. Am J Physiol Cell Physiol 286: C785-C791.
20. Hanover JA, Forsythe ME, Hennessey PT, Brodigan TM, Love DC, et al. (2005) A Caenorhabditis elegans model of insulin resistance: Altered macronutrient storage and dauer formation in an OGT-1 knockout. Proc Natl Acad Sci USA 102: 11266-11271.
21. Frazier HN, Roth MB, (2009) Adaptive sugar provisioning controls survival of C. elegans embryos in adverse environments. Curr Biol 19: 859-863.
22. Castro PV, Khare S, Young BD, Clarke SG, (2012) Caenorhabditis elegans battling starvation stress: Low levels of ethanol prolong lifespan in L1 larvae. PLoS One 7.
23. Riddle DL, Albert PS (1997) Genetic and environmental regulation of dauer larva development; Riddle DL, Blumenthal T, Meyer BJ, Priess JR, editors. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
24. Sutphin GL, Kaeberlein M, (2008) Dietary restriction by bacterial deprivation increases life span in wild-derived nematodes. Exp Gerontol 43: 130-135.
25. Seidel HS, Kimble J, (2011) The oogenic germline starvation response in C. elegans. PLoS One 6: e28074.
26. Angelo G, Van Gilst MR, (2009) Starvation protects germline stem cells and extends reproductive longevity in C. elegans. Science 326: 954-958.
27. Kaeberlein TL, Smith ED, Tsuchiya M, Welton KL, Thomas JH, et al. (2006) Lifespan extension in Caenorhabditis elegans by complete removal of food. Aging Cell 5: 487-494.
28. O'Rourke EJ, Soukas AA, Carr CE, Ruvkun G, (2009) C. elegans major fats are stored in vesicles distinct from lysosome-related organelles. Cell Metabol 10: 430-435.
29. Soukas AA, Kane EA, Carr CE, Melo JA, Ruvkun G, (2009) Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans. Gen Dev 23: 496-511.
30. Lemieux GA, Liu J, Mayer N, Bainton RJ, Ashrafi K, et al. (2011) A whole-organism screen identifies new regulators of fat storage. Nat Chem Bio 7: 206-213.
31. Hellerer T, Axang C, Brackmann C, Hillertz P, Pilon M, et al. (2007) Monitoring of lipid storage in Caenorhabditis elegans using coherent anti-Stokes Raman scattering (CARS) microscopy. Proc Natl Acad Sci USA 104: 14658-14663.
32. Avery L, Horvitz HR, (1990) Effects of starvation and neuroactive drugs on feeding in Caenorhabditis elegans. J Exp Zool 253: 263-270.
33. Hulme SE, Shevkoplyas SS, McGuigan AP, Apfeld J, Fontana W, et al. (2010) Lifespan-on-a-chip: microfluidic chambers for performing lifelong observation of C. elegans. Lab Chip 10: 589-597.
34. Perez CL, Van Gilst MR, (2008) A 13C Isotope labeling strategy reveals the influence of insulin signaling on lipogenesis in C. elegans. Cell Metabol 8: 266-274.
35. Miersch C, Doring F, (2012) Sex differences in carbohydrate metabolism are linked to gene expression in Caenorhabditis elegans. PLoS One 7.
36. Azevedo RBR, Keighdey PD, Lauren-Maatta C, Vassilieva LL, Lynch M, et al. (2002) Spontaneous mutational variation for body size in Caenorhabditis elegans. Genetics 162: 755-765.
37. Brozek J, Anderson JT, Keys A, Grande F, (1963) Densiometric analysis of body composition revision of some quantiative assumptions. Ann NY Acad Sci 110: 113-140.
38. Durnin J, Womersle J, (1974) Body fat assessed from total-body density and its estimation from skinfold thickness-Measurements on 481 men and women aged from 16 to 72 years. Br J Nutr 32: 77-97.
39. Reis T, Van Gilst MR, Hariharan IK, (2010) A buoyancy-based screen of Drosophila larvae for fat-storage mutants reveals a role for Sir2 in coupling fat storage to nutrient availability. PLoS Genet pp. 6.
40. Chen JJ, Caswell-Chen EP, (2004) Facultative vivipary is a life-history trait in Caenorhabditis elegans. J Nematol 36: 107-113.
41. Cox GN, Staprans S, Edgar RS, (1981) The cuticle of Caenorhabditis elegans. 2. Stage-specific changes in ultrastructure and protein-composition during post-embryonic development. Dev Biol 86: 456-470.
42. Greenstein D. Control of oocyte meiotic maturation and fertilization (December 28, 2005), WormBook, ed. The C. elegans Research Community.
43. Bridgman WB, (1942) Some physical chemical characteristics of glycogen. J Am Chem Soc 64: 2349-2356.
44. Stiernagle T. Maintenance of C. elegans (February 11, 2006), WormBook, ed. The C. elegans Research Community.