Identification of cancer-associated proteins by proteomics and downregulation of β-tropomyosin expression in colorectal adenoma and cancer

Proteomics - Clinical Applications

Volumn 3, Issue 12, 2009, Pages 1397-1406

  Luo, Yan Xin ^a   Cui, Ji ^a   Wang, Lei ^a   Chen, Dian Ke ^a   Peng, Jun Sheng ^a   Lan, Ping ^a   Huang, Mei Jin ^a   Huang, Yi Hua ^a   Cai, Shi Rong ^a   Hu, Kun Hua ^b   Li, Ming Tao ^b   Wang, Jian Ping ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

Tropomyosin; Adenoma; Colorectal cancer

Indexed keywords

BETA TROPOMYOSIN; TROPOMYOSIN; UNCLASSIFIED DRUG;

ADULT; AGED; AMINO ACID SEQUENCE; ARTICLE; COLON CARCINOGENESIS; COLORECTAL ADENOMA; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TWO DIMENSIONAL GEL ELECTROPHORESIS; UPREGULATION; WESTERN BLOTTING;

EID: 77951027427     PISSN: 18628346     EISSN: 18628354     Source Type: Journal    
DOI: 10.1002/prca.200900070     Document Type: Article

References (60)

1. Weitz, J., Koch, M., Debus, J., Hohler, T. et al., Colorectal cancer. Lancet 2005, 365, 153-165.
2. Anderson, W. F., Umar, A., Brawley, O. W., Colorectal carcinoma in black and white race. Cancer Metastasis Rev. 2003, 22, 67-82.
3. You, W. C., Jin, F., Devesa, S., Gridley, G. et al., Rapid increase in colorectal cancer rates in urban Shanghai, 1972-97, in relation to dietary changes. J. Cancer Epidemiol. Prev. 2002, 7, 143-146.
4. Pfister, D. G., Benson, A. B., Somerfield, M. R., Clinical practice. Surveillance strategies after curative treatment of colorectal cancer. N. Engl. J. Med. 2004, 350, 2375-2382.
5. Penland, S. K., Goldberg, R. M., Current strategies in previously untreated advanced colorectal cancer. Oncology (Williston Park) 2004, 18, 715-722, 727; discussion 727-729.
6. Mano, M. S., Duhoux, F., Colon cancer: update on adjuvant therapy. Clin. Colorectal Cancer 2008, 7, 178-183.
7. Vogelstein, B., Fearon, E. R., Hamilton, S. R., Kern, S. E. et al., Genetic alterations during colorectal-tumor development. N. Engl. J. Med. 1988, 319, 525-532.
8. Winawer, S. J., Zauber, A. G., Ho, M. N., O, B. M. et al., Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup. N. Engl. J. Med. 1993, 329, 1977-1981.
9. Ruo, L., Gougoutas, C., Paty, P. B., Guillem, J. G. et al., Elective bowel resection for incurable stage IV colorectal cancer: prognostic variables for asymptomatic patients. J. Am. Coll. Surg. 2003, 196, 722-728.
10. Hawk, E. T., Levin, B., Colorectal cancer prevention. J. Clin. Oncol. 2005, 23, 378-391.
11. Rubesin, S. E., Levine, M. S., Laufer, I., Herlinger, H., Double-contrast barium enema examination technique. Radiology 2000, 215, 642-650.
12. Anderson, M. L., Heigh, R. I., McCoy, G. A., Parent, K. et al., Accuracy of assessment of the extent of examination by experienced colonoscopists. Gastrointest. Endosc. 1992, 38, 560-563.
13. Otto, S., Eckhardt, S., Early detection for colorectal cancer: new aspects in fecal occult blood screening. J. Surg. Oncol. 2000, 75, 220-226.
14. de, N. M., Tollenaar, R. A., Deelder, A. M., Bouwman, L. H., Current status and prospects of clinical proteomics studies on detection of colorectal cancer: hopes and fears. World J. Gastroenterol. 2006, 12, 6594-6601.
15. Birkenkamp-Demtroder, K., Christensen, L. L., Olesen, S. H., Frederiksen, C. M. et al., Gene expression in colorectal cancer. Cancer Res. 2002, 62, 4352-4363.
16. Frederiksen, C. M., Knudsen, S., Laurberg, S., Orntoft, T. F., Classification of Dukes' B and C colorectal cancers using expression arrays. J. Cancer Res. Clin. Oncol. 2003, 129, 263-271.
17. Arango, D., Laiho, P., Kokko, A., Alhopuro, P. et al., Geneexpression profiling predicts recurrence in Dukes' C colorectal cancer. Gastroenterology 2005, 129, 874-884.
18. Williams, N. S., Gaynor, R. B., Scoggin, S., Verma, U. et al., Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference. Clin. Cancer Res. 2003, 9, 931-946.
19. Rajagopalan, H., Nowak, M. A., Vogelstein, B., Lengauer, C., The significance of unstable chromosomes in colorectal cancer. Nat. Rev. Cancer 2003, 3, 695-701.
20. Bellacosa, A., Genetic hits and mutation rate in colorectal tumorigenesis: versatility of Knudson's theory and implications for cancer prevention. Genes Chromosomes Cancer 2003, 38, 382-388.
21. Posadas, E. M., Simpkins, F., Liotta, L. A., MacDonald, C. et al., Proteomic analysis for the early detection and rational treatment of cancer - realistic hope? Ann. Oncol. 2005, 16, 16-22.
22. Chambers, G., Lawrie, L., Cash, P., Murray, G. I., Proteomics: a new approach to the study of disease. J. Pathol. 2000, 192, 280-288.
23. Friedman, D. B., Hill, S., Keller, J. W., Merchant, N. B. et al., Proteome analysis of human colon cancer by two-dimensional difference gel electrophoresis and mass spectrometry. Proteomics 2004, 4, 793-811.
24. Alfonso, P., Nunez, A., Madoz-Gurpide, J., Lombardia, L. et al., Proteomic expression analysis of colorectal cancer by two-dimensional differential gel electrophoresis. Proteomics 2005, 5, 2602-2611.
25. Unlu, M., Morgan, M. E., Minden, J. S., Difference gel electrophoresis: a single gel method for detecting changes in protein extracts. Electrophoresis 1997, 18, 2071-2077.
26. Jin, S., Shen, J., Guo, Q., Zhou, J. et al., 2-D DIGE and MALDI-TOF-MS analysis of the serum proteome in human osteosarcoma. Proteomics Clin. Appl. 2007, 1, 272-285.
27. Etienne-Grimaldi, M. C., Formento, J. L., Francoual, M., Francois, E. et al., K-Ras mutations and treatment outcome in colorectal cancer patients receiving exclusive fluoropyrimidine therapy. Clin. Cancer Res. 2008, 14, 4830-4835.
28. Bakin, A. V., Safina, A., Rinehart, C., Daroqui, C. et al., A critical role of tropomyosins in TGF-beta regulation of the actin cytoskeleton and cell motility in epithelial cells. Mol. Biol. Cell 2004, 15, 4682-4694.
29. Prasad, G. L., Fuldner, R. A., Cooper, H. L., Expression of transduced tropomyosin 1 cDNA suppresses neoplastic growth of cells transformed by the ras oncogene. Proc. Natl. Acad. Sci. USA 1993, 90, 7039-7043.
30. Shah, V., Bharadwaj, S., Kaibuchi, K., Prasad, G. L., Cytoskeletal organization in tropomyosin-mediated reversion of ras-transformation: evidence for Rho kinase pathway. Oncogene 2001, 20, 2112-2121.
31. Jazii, F. R., Najafi, Z., Malekzadeh, R., Conrads, T. P. et al., Identification of squamous cell carcinoma associated proteins by proteomics and loss of beta tropomyosin expression in esophageal cancer. World J. Gastroenterol. 2006, 12, 7104-7112.
32. Alban, A., David, S. O., Bjorkesten, L., Andersson, C. et al., A novel experimental design for comparative two-dimensional gel analysis: two-dimensional difference gel electrophoresis incorporating a pooled internal standard. Proteomics 2003, 3, 36-44.
33. Sharma, K., Lee, S., Han, S., Lee, S. et al., Two-dimensional fluorescence difference gel electrophoresis analysis of the urine proteome in human diabetic nephropathy. Proteomics 2005, 5, 2648-2655.
34. Griffin, T. J., Gygi, S. P., Ideker, T., Rist, B. et al., Complementary profiling of gene expression at the transcriptome and proteome levels in Saccharomyces cerevisiae. Mol. Cell Proteomics 2002, 1, 323-333.
35. Wang, Y., Ma, Y., Lu, B., Xu, E. et al., Differential expression of mimecan and thioredoxin domain-containing protein 5 in colorectal adenoma and cancer: a proteomic study. Exp. Biol. Med. (Maywood) 2007, 232, 1152-1159.
36. Petrova, D. T., Asif, A. R., Armstrong, V. W., Dimova, I. et al., Expression of chloride intracellular channel protein 1 (CLIC1) and tumor protein D52 (TPD52) as potential biomarkers for colorectal cancer. Clin. Biochem. 2008, 41, 1224-1236.
37. Juan, H. F., Chen, J. H., Hsu, W. T., Huang, S. C. et al., Identification of tumor-associated plasma biomarkers using proteomic techniques: from mouse to human. Proteomics 2004, 4, 2766-2775.
38. Li, M., Xiao, Z. Q., Chen, Z. C., Li, J. L. et al., Proteomic analysis of the aging-related proteins in human normal colon epithelial tissue. J. Biochem. Mol. Biol. 2007, 40, 72-81.
39. Moll, R., Molecular diversity of cytokeratins: significance for cell and tumor differentiation. Acta Histochem. Suppl. 1991, 41, 117-127.
40. Baribault, H., Penner, J., Iozzo, R. V., Wilson-Heiner, M., Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice. Genes Dev. 1994, 8, 2964-2973.
41. Toivola, D. M., Krishnan, S., Binder, H. J., Singh, S. K. et al., Keratins modulate colonocyte electrolyte transport via protein mistargeting. J. Cell Biol. 2004, 164, 911-921.
42. Owens, D. W., Wilson, N. J., Hill, A. J., Rugg, E. L. et al., Human keratin 8 mutations that disturb filament assembly observed in inflammatory bowel disease patients. J. Cell Sci. 2004, 117, 1989-1999.
43. Ku, N. O., Strnad, P., Zhong, B. H., Tao, G. Z. et al., Keratins let liver live: mutations predispose to liver disease and crosslinking generates Mallory-Denk bodies. Hepatology 2007, 46, 1639-1649.
44. Clevers, H., At the crossroads of inflammation and cancer. Cell 2004, 118, 671-674.
45. Toivola, D. M., Nakamichi, I., Strnad, P., Michie, S. A. et al., Keratin overexpression levels correlate with the extent of spontaneous pancreatic injury. Am. J. Pathol. 2008, 172, 882-892.
46. Casanova, M. L., Bravo, A., Ramirez, A., Morreale, E. G. et al., Exocrine pancreatic disorders in transgenic mice expressing human keratin 8. J. Clin. Invest. 1999, 103, 1587-1595.
47. Habtezion, A., Toivola, D. M., Butcher, E. C., Omary, M. B., Keratin-8-deficient mice develop chronic spontaneous Th2 colitis amenable to antibiotic treatment. J. Cell Sci. 2005, 118, 1971-1980.
48. Freedman, R. B., Hirst, T. R., Tuite, M. F., Protein disulphide isomerase: building bridges in protein folding. Trends Biochem. Sci. 1994, 19, 331-336.
49. Higuchi, T., Watanabe, Y., Waga, I., Protein disulfide isomerase suppresses the transcriptional activity of NF-kB. Biochem. Biophys. Res. Commun. 2004, 318, 46-52.
50. Barnes, P. J., Karin, M., Nuclear factor-kappa B: a pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 1997, 336, 1066-1071.
51. Franzen, B., Linder, S., Uryu, K., Alaiya, A. A. et al., Expression of tropomyosin isoforms in benign and malignant human breast lesions. Br. J. Cancer 1996, 73, 909-913.
52. He, Q. Y., Chen, J., Kung, H. F., Yuen, A. P. et al., Identification of tumor-associated proteins in oral tongue squamous cell carcinoma by proteomics. Proteomics 2004, 4, 271-278.
53. Mahadev, K., Raval, G., Bharadwaj, S., Willingham, M. C. et al., Suppression of the transformed phenotype of breast cancer by tropomyosin-1. Exp. Cell Res. 2002, 279, 40-51.
54. Raval, G. N., Bharadwaj, S., Levine, E. A., Willingham, M. C. et al., Loss of expression of tropomyosin-1, a novel class II tumor suppressor that induces anoikis, in primary breast tumors. Oncogene 2003, 22, 6194-6203.
55. Zheng, Q., Safina, A., Bakin, A. V., Role of high-molecular weight tropomyosins in TGF-beta-mediated control of cell motility. Int. J. Cancer 2008, 122, 78-90.
56. Janssen, R. A., Kim, P. N., Mier, J. W., Morrison, D. K., Overexpression of kinase suppressor of Ras upregulates the high-molecular-weight tropomyosin isoforms in rastransformed NIH 3T3 fibroblasts. Mol. Cell Biol. 2003, 23, 1786-1797.
57. Bellacosa, A., Genetic hits and mutation rate in colorectal tumorigenesis: versatility of Knudson's theory and implications for cancer prevention. Genes Chromosomes Cancer 2003, 38, 382-388.
58. Rajagopalan, H., Nowak, M. A., Vogelstein, B., Lengauer, C., The significance of unstable chromosomes in colorectal cancer. Nat. Rev. Cancer 2003, 3, 695-701.
59. Malumbres, M., Barbacid, M., RAS oncogenes: the first 30 years. Nat. Rev. Cancer 2003, 3, 459-465.
60. Shields, J. M., Mehta, H., Pruitt, K., Der, C. J., Opposing roles of the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in Rasmediated downregulation of tropomyosin. Mol. Cell Biol. 2002, 22, 2304-2317.