Lysine-Specific Demethylase 1 (LSD1/KDM1A) Contributes to Colorectal Tumorigenesis via Activation of the Wnt/Β-Catenin Pathway by Down-Regulating Dickkopf-1 (DKK1)

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Huang, Zebin ^a   Li, Shangze ^b   Song, Wei ^a   Li, Xin ^b   Li, Qinshan ^a   Zhang, Zeyan ^b   Han, Yongqing ^a   Zhang, Xiaodong ^b   Miao, Shiying ^a   Du, Runlei ^b   Wang, Linfang ^a  

^a TSINGHUA UNIVERSITY   (China)

^b WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); BETA CATENIN; DICKKOPF 1 PROTEIN; LYSINE SPECIFIC DEMETHYLASE 1; MESSENGER RNA; UNCLASSIFIED DRUG;

ADM GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; CELL NUCLEUS; CELL STRAIN HCT116; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; COLONY FORMATION; COLORECTAL CARCINOMA; CONTROLLED STUDY; DKK1 GENE; DOWN REGULATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HAS3 GENE; HISTONE METHYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE C MYC; REAL TIME POLYMERASE CHAIN REACTION; RNA SEQUENCE; SMURF2 GENE; TUMOR GENE; WNT SIGNALING PATHWAY;

BETA CATENIN; CARCINOGENESIS; CELL LINE, TUMOR; COLON; COLORECTAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKOUT TECHNIQUES; HISTONE DEMETHYLASES; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84880809630     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070077     Document Type: Article

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