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Volumn 31, Issue 2, 2010, Pages 202-210

Downregulation of Dickkopf-1 is responsible for high proliferation of breast cancer cells via losing control of Wnt/Β-catenin signaling

Author keywords

Breast cancer; Cell proliferation; Dickkopf 1; MCF 7 cell line; Survivin; Wnt catenin

Indexed keywords

BETA CATENIN; BROXURIDINE; CYCLIN D1; DICKKOPF 1 PROTEIN; LUCIFERASE; MESSENGER RNA; MYC PROTEIN; PLASMID DNA; SMALL INTERFERING RNA; SURVIVIN; WNT PROTEIN;

EID: 76949086190     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2009.200     Document Type: Article
Times cited : (43)

References (40)
  • 1
    • 31144465887 scopus 로고    scopus 로고
    • Screening of a sub-clone of human breast cancer cells with high metastasis potential
    • Ye L, Wu L, Guo W, Ma H, Zhang X. Screening of a sub-clone of human breast cancer cells with high metastasis potential. Zhonghua Yi Xue Za Zhi 2006; 86: 61-5.
    • (2006) Zhonghua Yi Xue Za Zhi , vol.86 , pp. 61-65
    • Ye, L.1    Wu, L.2    Guo, W.3    Ma, H.4    Zhang, X.5
  • 2
    • 22944485022 scopus 로고    scopus 로고
    • Screening metastasisassociated genes in breast cancer cells with different matastatic ability by cDNA microarray
    • Ye L, You J, Qiao L, Cai N, Wang C, Liu Y, et al. Screening metastasisassociated genes in breast cancer cells with different matastatic ability by cDNA microarray. Prog Biochem Biophys 2005; 32: 421-8.
    • (2005) Prog Biochem Biophys , vol.32 , pp. 421-428
    • Ye, L.1    You, J.2    Qiao, L.3    Cai, N.4    Wang, C.5    Liu, Y.6
  • 3
    • 52149114882 scopus 로고    scopus 로고
    • Myosin light-chain kinase contributes to the proliferation and migration of breast cancer cells through cross-talk with activated ERK1/2
    • Zhou X, Liu Y, You J, Zhang H, Zhang X, Ye L. Myosin light-chain kinase contributes to the proliferation and migration of breast cancer cells through cross-talk with activated ERK1/2. Cancer Lett 2008; 270: 312-27.
    • (2008) Cancer Lett , vol.270 , pp. 312-327
    • Zhou, X.1    Liu, Y.2    You, J.3    Zhang, H.4    Zhang, X.5    Ye, L.6
  • 4
    • 63849232779 scopus 로고    scopus 로고
    • A positive feedback between activated extracellularly regulated kinase and cyclooxygenase/lipoxygenase maintains proliferation and migration of breast cancer cells
    • You J, Mi D, Zhou X, Qiao L, Zhang H, Zhang X, et al. A positive feedback between activated extracellularly regulated kinase and cyclooxygenase/ lipoxygenase maintains proliferation and migration of breast cancer cells. Endocrinology 2009; 150: 1607-17.
    • (2009) Endocrinology , vol.150 , pp. 1607-1617
    • You, J.1    Mi, D.2    Zhou, X.3    Qiao, L.4    Zhang, H.5    Zhang, X.6
  • 5
    • 27944446105 scopus 로고    scopus 로고
    • Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT
    • Yoeli-Lerner M, Yiu GK, Rabinovitz I, Erhardt P, Jauliac S, Toker A. Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT. Mol Cell 2005; 20: 539-50.
    • (2005) Mol Cell , vol.20 , pp. 539-550
    • Yoeli-Lerner, M.1    Yiu, G.K.2    Rabinovitz, I.3    Erhardt, P.4    Jauliac, S.5    Toker, A.6
  • 6
    • 40949092796 scopus 로고    scopus 로고
    • NOTCH3 signaling pathway plays crucial roles in the proliferation of ErbB2-negative human breast cancer cells
    • Yamaguchi N, Oyama T, Ito E, Satoh H, Azuma S, Hayashi M, et al. NOTCH3 signaling pathway plays crucial roles in the proliferation of ErbB2-negative human breast cancer cells. Cancer Res 2008; 68: 1881-8.
    • (2008) Cancer Res , vol.68 , pp. 1881-1888
    • Yamaguchi, N.1    Oyama, T.2    Ito, E.3    Satoh, H.4    Azuma, S.5    Hayashi, M.6
  • 7
    • 2342604466 scopus 로고    scopus 로고
    • Essential function for ErbB3 in breast cancer proliferation
    • Perez-Nadales E, Lloyd AC. Essential function for ErbB3 in breast cancer proliferation. Breast Cancer Res 2004; 6: 137-9.
    • (2004) Breast Cancer Res , vol.6 , pp. 137-139
    • Perez-Nadales, E.1    Lloyd, A.C.2
  • 8
    • 27744608602 scopus 로고    scopus 로고
    • Coordinate expression of the PI3-kinase downstream effectors serum and glucocorticoid-induced kinase (SGK-1) and Akt-1 in human breast cancer
    • Sahoo S, Brickley DR, Kocherginsky M, Conzen SD. Coordinate expression of the PI3-kinase downstream effectors serum and glucocorticoid-induced kinase (SGK-1) and Akt-1 in human breast cancer. Eur J Cancer 2005; 41: 2754-9.
    • (2005) Eur J Cancer , vol.41 , pp. 2754-2759
    • Sahoo, S.1    Brickley, D.R.2    Kocherginsky, M.3    Conzen, S.D.4
  • 9
    • 57249108188 scopus 로고    scopus 로고
    • Suppression of Wnt/beta-catenin signaling inhibits prostate cancer cell proliferation
    • Lu W, Tinsley HN, Keeton A, Qu Z, Piazza GA, Li Y. Suppression of Wnt/beta-catenin signaling inhibits prostate cancer cell proliferation. Eur J Pharmacol 2009; 602: 8-14.
    • (2009) Eur J Pharmacol , vol.602 , pp. 8-14
    • Lu, W.1    Tinsley, H.N.2    Keeton, A.3    Qu, Z.4    Piazza, G.A.5    Li, Y.6
  • 12
    • 1642430935 scopus 로고    scopus 로고
    • Wnt breakers in colon cancer
    • Clevers H. Wnt breakers in colon cancer. Cancer Cell 2004; 5: 5-6.
    • (2004) Cancer Cell , vol.5 , pp. 5-6
    • Clevers, H.1
  • 13
    • 0033516577 scopus 로고    scopus 로고
    • Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling
    • Fedi P, Bafico A, Nieto Soria A, Burgess WH, Miki T, Bottaro DP, et al. Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling. J Biol Chem 1999; 274: 19465-72.
    • (1999) J Biol Chem , vol.274 , pp. 19465-19472
    • Fedi, P.1    Bafico, A.2    Nieto Soria, A.3    Burgess, W.H.4    Miki, T.5    Bottaro, D.P.6
  • 14
    • 0034933057 scopus 로고    scopus 로고
    • Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow
    • Bafico A, Liu G, Yaniv A, Gazit A, Aaronson SA. Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nat Cell Biol 2001; 3: 683-6.
    • (2001) Nat Cell Biol , vol.3 , pp. 683-686
    • Bafico, A.1    Liu, G.2    Yaniv, A.3    Gazit, A.4    Aaronson, S.A.5
  • 15
    • 0037030681 scopus 로고    scopus 로고
    • Kremen proteins are Dickkopf receptors that regulate Wnt/betacatenin signalling
    • Mao B, Wu W, Davidson G, Marhold J, Li M, Mechler BM, et al. Kremen proteins are Dickkopf receptors that regulate Wnt/betacatenin signalling. Nature 2002; 417: 664-7.
    • (2002) Nature , vol.417 , pp. 664-667
    • Mao, B.1    Wu, W.2    Davidson, G.3    Marhold, J.4    Li, M.5    Mechler, B.M.6
  • 16
    • 0035902050 scopus 로고    scopus 로고
    • LDL-receptorrelated protein 6 is a receptor for Dickkopf proteins
    • Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A, et al. LDL-receptorrelated protein 6 is a receptor for Dickkopf proteins. Nature 2001; 411: 321-5.
    • (2001) Nature , vol.411 , pp. 321-325
    • Mao, B.1    Wu, W.2    Li, Y.3    Hoppe, D.4    Stannek, P.5    Glinka, A.6
  • 17
    • 13944282066 scopus 로고    scopus 로고
    • The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer
    • Gonzalez-Sancho JM, Aguilera O, Garcia JM, Pendas-Franco N, Pena C, Cal S, et al. The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer. Oncogene 2005; 24: 1098-103.
    • (2005) Oncogene , vol.24 , pp. 1098-1093
    • Gonzalez-Sancho, J.M.1    Aguilera, O.2    Garcia, J.M.3    Pendas-Franco, N.4    Pena, C.5    Cal, S.6
  • 18
    • 33745765883 scopus 로고    scopus 로고
    • Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer
    • Aguilera O, Fraga MF, Ballestar E, Paz MF, Herranz M, Espada J, et al. Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer. Oncogene 2006; 25: 4116-21.
    • (2006) Oncogene , vol.25 , pp. 4116-4121
    • Aguilera, O.1    Fraga, M.F.2    Ballestar, E.3    Paz, M.F.4    Herranz, M.5    Espada, J.6
  • 19
    • 7944230668 scopus 로고    scopus 로고
    • An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells
    • Bafico A, Liu G, Goldin L, Harris V, Aaronson SA. An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells. Cancer Cell 2004; 6: 497-506.
    • (2004) Cancer Cell , vol.6 , pp. 497-506
    • Bafico, A.1    Liu, G.2    Goldin, L.3    Harris, V.4    Aaronson, S.A.5
  • 21
    • 11144354692 scopus 로고    scopus 로고
    • Mesenchymal-epithelial interactions in the skin: Increased expression of dickkopf1 by palmoplantar fibroblasts inhibits melanocyte growth and differentiation
    • Yamaguchi Y, Itami S, Watabe H, Yasumoto K, Abdel-Malek ZA, Kubo T, et al. Mesenchymal-epithelial interactions in the skin: increased expression of dickkopf1 by palmoplantar fibroblasts inhibits melanocyte growth and differentiation. J Cell Biol 2004; 165: 275-85.
    • (2004) J Cell Biol , vol.165 , pp. 275-285
    • Yamaguchi, Y.1    Itami, S.2    Watabe, H.3    Yasumoto, K.4    Abdel-Malek, Z.A.5    Kubo, T.6
  • 22
    • 49349100584 scopus 로고    scopus 로고
    • Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signalling
    • Qiao L, Xu ZL, Zhao TJ, Ye LH, Zhang XD. Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signalling. Cancer Lett 2008; 269: 67-77.
    • (2008) Cancer Lett , vol.269 , pp. 67-77
    • Qiao, L.1    Xu, Z.L.2    Zhao, T.J.3    Ye, L.H.4    Zhang, X.D.5
  • 23
    • 0034782172 scopus 로고    scopus 로고
    • Establishment of cell clones with different metastatic potential from the metastatic hepatocellular carcinoma cell line MHCC97
    • Li Y, Tang ZY, Ye SL, Liu YK, Chen J, Xue Q, et al. Establishment of cell clones with different metastatic potential from the metastatic hepatocellular carcinoma cell line MHCC97. World J Gastroenterol 2001; 7: 630-6.
    • (2001) World J Gastroenterol , vol.7 , pp. 630-636
    • Li, Y.1    Tang, Z.Y.2    Ye, S.L.3    Liu, Y.K.4    Chen, J.5    Xue, Q.6
  • 24
    • 35348998631 scopus 로고    scopus 로고
    • Proliferation and migration mediated by Dkk-1/Wnt/beta-catenin cascade in a model of hepatocellular carcinoma cells
    • Qin X, Zhang H, Zhou X, Wang C, Zhang X, Ye L. Proliferation and migration mediated by Dkk-1/Wnt/beta-catenin cascade in a model of hepatocellular carcinoma cells. Transl Res 2007; 150: 281-94.
    • (2007) Transl Res , vol.150 , pp. 281-294
    • Qin, X.1    Zhang, H.2    Zhou, X.3    Wang, C.4    Zhang, X.5    Ye, L.6
  • 25
    • 24744439747 scopus 로고    scopus 로고
    • Prostate cancer cells promote osteoblastic bone metastases through Wnts
    • Hall CL, Bafico A, Dai J, Aaronson SA, Keller ET. Prostate cancer cells promote osteoblastic bone metastases through Wnts. Cancer Res 2005; 65: 7554-60.
    • (2005) Cancer Res , vol.65 , pp. 7554-7560
    • Hall, C.L.1    Bafico, A.2    Dai, J.3    Aaronson, S.A.4    Keller, E.T.5
  • 26
    • 33847201190 scopus 로고    scopus 로고
    • Involvement of hepatitis B X-interacting protein (HBXIP) in proliferation regulation of cells
    • Wang FZ, Sha L, Zhang WY, Wu LY, Qiao L, Li N, et al. Involvement of hepatitis B X-interacting protein (HBXIP) in proliferation regulation of cells. Acta Pharmacol Sin 2007; 28: 431-8.
    • (2007) Acta Pharmacol Sin , vol.28 , pp. 431-438
    • Wang, F.Z.1    Sha, L.2    Zhang, W.Y.3    Wu, L.Y.4    Qiao, L.5    Li, N.6
  • 27
    • 33747850523 scopus 로고    scopus 로고
    • Targeted inhibition of p57 and p15 blocks transforming growth factor betainhibited proliferation of primary cultured human limbal epithelial cells
    • Chen Z, Li DQ, Tong L, Stewart P, Chu C, Pflugfelder SC. Targeted inhibition of p57 and p15 blocks transforming growth factor betainhibited proliferation of primary cultured human limbal epithelial cells. Mol Vis 2006; 12: 983-94.
    • (2006) Mol Vis , vol.12 , pp. 983-994
    • Chen, Z.1    Li, D.Q.2    Tong, L.3    Stewart, P.4    Chu, C.5    Pflugfelder, S.C.6
  • 28
    • 0037045429 scopus 로고    scopus 로고
    • Reduced expression of the REIC/Dkk-3 gene by promoterhypermethylation in human tumor cells
    • Kobayashi K, Ouchida M, Tsuji T, Hanafusa H, Miyazaki M, Namba M, et al. Reduced expression of the REIC/Dkk-3 gene by promoterhypermethylation in human tumor cells. Gene 2002; 282: 151-8.
    • (2002) Gene , vol.282 , pp. 151-158
    • Kobayashi, K.1    Ouchida, M.2    Tsuji, T.3    Hanafusa, H.4    Miyazaki, M.5    Namba, M.6
  • 30
    • 0034732151 scopus 로고    scopus 로고
    • Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53
    • Wang J, Shou J, Chen X. Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53. Oncogene 2000; 19: 1843-8.
    • (2000) Oncogene , vol.19 , pp. 1843-1848
    • Wang, J.1    Shou, J.2    Chen, X.3
  • 31
    • 40449138006 scopus 로고    scopus 로고
    • Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation
    • Schlange T, Matsuda Y, Lienhard S, Huber A, Hynes NE. Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation. Breast Cancer Res 2007; 9: R63.
    • (2007) Breast Cancer Res , vol.9
    • Schlange, T.1    Matsuda, Y.2    Lienhard, S.3    Huber, A.4    Hynes, N.E.5
  • 34
    • 2342430345 scopus 로고    scopus 로고
    • LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: Arrows point the way
    • He X, Semenov M, Tamai K, Zeng X. LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. Development 2004; 131: 1663-77.
    • (2004) Development , vol.131 , pp. 1663-1677
    • He, X.1    Semenov, M.2    Tamai, K.3    Zeng, X.4
  • 35
    • 0026096540 scopus 로고
    • Control of c-myc regulation in normal and neoplastic cells
    • Spencer CA, Groudine M. Control of c-myc regulation in normal and neoplastic cells. Adv Cancer Res 1991; 56: 1-48.
    • (1991) Adv Cancer Res , vol.56 , pp. 1-48
    • Spencer, C.A.1    Groudine, M.2
  • 36
    • 35349029694 scopus 로고    scopus 로고
    • Breast cancer cell proliferation is inhibited by BAD: Regulation of cyclin D1
    • Fernando R, Foster JS, Bible A, Strom A, Pestell RG, Rao M, et al. Breast cancer cell proliferation is inhibited by BAD: regulation of cyclin D1. J Biol Chem 2007; 282: 28864-73.
    • (2007) J Biol Chem , vol.282 , pp. 28864-28873
    • Fernando, R.1    Foster, J.S.2    Bible, A.3    Strom, A.4    Pestell, R.G.5    Rao, M.6
  • 37
    • 3442894128 scopus 로고    scopus 로고
    • An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth
    • You L, He B, Xu Z, Uematsu K, Mazieres J, Fujii N, et al. An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth. Cancer Res 2004; 64: 5385-9.
    • (2004) Cancer Res , vol.64 , pp. 5385-5389
    • You, L.1    He, B.2    Xu, Z.3    Uematsu, K.4    Mazieres, J.5    Fujii, N.6
  • 38
    • 0035893568 scopus 로고    scopus 로고
    • Evidence that APC regulates survivin expression: A possible mechanism contributing to the stem cell origin of colon cancer
    • Zhang T, Otevrel T, Gao Z, Ehrlich SM, Fields JZ, Boman BM. Evidence that APC regulates survivin expression: a possible mechanism contributing to the stem cell origin of colon cancer. Cancer Res 2001; 61: 8664-7.
    • (2001) Cancer Res , vol.61 , pp. 8664-8667
    • Zhang, T.1    Otevrel, T.2    Gao, Z.3    Ehrlich, S.M.4    Fields, J.Z.5    Boman, B.M.6
  • 39
    • 0038182537 scopus 로고    scopus 로고
    • HBXIP functions as a cofactor of survivin in apoptosis suppression
    • Marusawa H, Matsuzawa S, Welsh K, Zou H, Armstrong R, Tamm I, et al. HBXIP functions as a cofactor of survivin in apoptosis suppression. EMBO J 2003; 22: 2729-40.
    • (2003) EMBO J , vol.22 , pp. 2729-2740
    • Marusawa, H.1    Matsuzawa, S.2    Welsh, K.3    Zou, H.4    Armstrong, R.5    Tamm, I.6
  • 40
    • 4644302254 scopus 로고    scopus 로고
    • Dickkopf-1 antagonizes Wnt signaling independent of beta-catenin in human mesothelioma
    • Lee AY, He B, You L, Xu Z, Mazieres J, Reguart N, et al. Dickkopf-1 antagonizes Wnt signaling independent of beta-catenin in human mesothelioma. Biochem Biophys Res Commun 2004; 323: 1246-50.
    • (2004) Biochem Biophys Res Commun , vol.323 , pp. 1246-1250
    • Lee, A.Y.1    He, B.2    You, L.3    Xu, Z.4    Mazieres, J.5    Reguart, N.6


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