Preparation of methotrexate-loaded, large, highly-porous PLLA microspheres by a high-voltage electrostatic antisolvent process

Journal of Materials Science: Materials in Medicine

Volumn 24, Issue 8, 2013, Pages 1917-1925

  Chen, Ai Zheng ^a   Yang, Yue Mei ^a   Wang, Shi Bin ^a   Wang, Guang Ya ^a   Liu, Yuan Gang ^a   Sun, Qing Qing ^a  

^a HUAQIAO UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISOLVENT PROCESS; DIMETHYL SULFOXIDE (DMSO); FOURIER TRANSFORM INFRA REDS; HIGH VOLTAGE APPARATUS; MASS MEDIAN AERODYNAMIC DIAMETERS; MEAN PARTICLE SIZE; POLYMER MICROSPHERES; PULMONARY DRUG DELIVERY;

DICHLOROMETHANE; DIMETHYL SULFOXIDE; DRUG PRODUCTS; ELECTROSTATICS; EMULSIFICATION; MICROSPHERES; ORGANIC SOLVENTS; X RAY DIFFRACTION;

TISSUE;

DICHLOROMETHANE; DIMETHYL SULFOXIDE; METHOTREXATE; MICROSPHERE; POLOXAMER; POLYLACTIDE; POROUS POLYMER;

AEROSOL; AQUEOUS SOLUTION; ARTICLE; CHEMICAL STRUCTURE; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG RELEASE; EMULSION; ENCAPSULATION; FREEZE DRYING; PARTICLE SIZE; POROSITY; PRECIPITATION; PRIORITY JOURNAL; STATIC ELECTRICITY; SURFACE CHARGE; ULTRASOUND; X RAY DIFFRACTION;

DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; METHOTREXATE; MICROSPHERES; MODELS, BIOLOGICAL; PARTICLE SIZE; POLYESTERS; POROSITY; SOLVENTS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STATIC ELECTRICITY; SURFACE PROPERTIES; X-RAY DIFFRACTION;

EID: 84880771860     PISSN: 09574530     EISSN: 15734838     Source Type: Journal    
DOI: 10.1007/s10856-013-4942-1     Document Type: Article

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