-
1
-
-
0037459077
-
Sticky business: orchestrating cellular signals at adherens junctions
-
Perez-Moreno M, Jamora C, Fuchs E. 2003. Sticky business: orchestrating cellular signals at adherens junctions. Cell 112:535-548.
-
(2003)
Cell
, vol.112
, pp. 535-548
-
-
Perez-Moreno, M.1
Jamora, C.2
Fuchs, E.3
-
2
-
-
41749089800
-
Modeling morphogenesis and oncogenesis in three-dimensional breast epithelial cultures
-
Hebner C, Weaver VM, Debnath J. 2008. Modeling morphogenesis and oncogenesis in three-dimensional breast epithelial cultures. Annu. Rev. Pathol. 3:313-339.
-
(2008)
Annu. Rev. Pathol.
, vol.3
, pp. 313-339
-
-
Hebner, C.1
Weaver, V.M.2
Debnath, J.3
-
4
-
-
42549164807
-
Wnt signalling and its impact on development and cancer
-
Klaus A, Birchmeier W. 2008. Wnt signalling and its impact on development and cancer. Nat. Rev. Cancer 8:387-398.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 387-398
-
-
Klaus, A.1
Birchmeier, W.2
-
5
-
-
73949086725
-
Wnt to build a tube: contributions of Wnt signaling to epithelial tubulogenesis
-
Miller RK, McCrea PD. 2010. Wnt to build a tube: contributions of Wnt signaling to epithelial tubulogenesis. Dev. Dyn. 239:77-93.
-
(2010)
Dev. Dyn.
, vol.239
, pp. 77-93
-
-
Miller, R.K.1
McCrea, P.D.2
-
6
-
-
77149174855
-
Wnt signaling from development to disease: insights from model systems
-
doi:10.1101/cshperspect.a002881.
-
Cadigan KM, Peifer M. 2009. Wnt signaling from development to disease: insights from model systems. Cold Spring Harb. Perspect. Biol. 1:a002881. doi:10.1101/cshperspect.a002881.
-
(2009)
Cold Spring Harb. Perspect. Biol.
, vol.1
-
-
Cadigan, K.M.1
Peifer, M.2
-
7
-
-
42649138943
-
Common activation of canonical Wnt signaling in pancreatic adenocarcinoma
-
doi:10.1371/journal.pone.0001155.
-
Pasca di Magliano M, Biankin AV, Heiser PW, Cano DA, Gutierrez PJA, Deramaudt T, Segara D, Dawson AC, Kench JG, Henshall SM, Sutherland RL, Dlugosz A, Rustgi AK, Hebrok M. 2007. Common activation of canonical Wnt signaling in pancreatic adenocarcinoma. PLoS One 2:e1155. doi:10.1371/journal.pone.0001155.
-
(2007)
PLoS One
, vol.2
-
-
Pasca di Magliano, M.1
Biankin, A.V.2
Heiser, P.W.3
Cano, D.A.4
Gutierrez, P.J.A.5
Deramaudt, T.6
Segara, D.7
Dawson, A.C.8
Kench, J.G.9
Henshall, S.M.10
Sutherland, R.L.11
Dlugosz, A.12
Rustgi, A.K.13
Hebrok, M.14
-
8
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
Reya T, Clevers H. 2005. Wnt signalling in stem cells and cancer. Nature 434:843-850.
-
(2005)
Nature
, vol.434
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
9
-
-
84863756127
-
Wnt signaling, stem cells, and cancer of the gastrointestinal tract
-
Schepers A, Clevers H. 2012. Wnt signaling, stem cells, and cancer of the gastrointestinal tract. Cold Spring Harb. Perspect. Biol. 4:a007989.
-
(2012)
Cold Spring Harb. Perspect. Biol.
, vol.4
-
-
Schepers, A.1
Clevers, H.2
-
10
-
-
33846193290
-
The many ways of Wnt in cancer
-
Polakis P. 2007. The many ways of Wnt in cancer. Curr. Opin. Genet. Dev. 17:45-51.
-
(2007)
Curr. Opin. Genet. Dev.
, vol.17
, pp. 45-51
-
-
Polakis, P.1
-
11
-
-
77952903266
-
Helicobacter pylori: gastric cancer and beyond
-
Polk DB, Peek RM. 2010. Helicobacter pylori: gastric cancer and beyond. Nat. Rev. Cancer 10:403-414.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 403-414
-
-
Polk, D.B.1
Peek, R.M.2
-
12
-
-
65349095556
-
Epstein-Barr virus-encoded latent membrane protein 1 activates β-catenin signaling in B lymphocytes
-
(Retraction in 102:500.)
-
Tomita M, Dewan MZ, Yamamoto N, Kikuchi A, Mori N. 2009. Epstein-Barr virus-encoded latent membrane protein 1 activates β-catenin signaling in B lymphocytes. Cancer Sci. 100:807-812. (Retraction in 102:500.)
-
(2009)
Cancer Sci
, vol.100
, pp. 807-812
-
-
Tomita, M.1
Dewan, M.Z.2
Yamamoto, N.3
Kikuchi, A.4
Mori, N.5
-
13
-
-
77955418239
-
Cystic kidney disease: the role of Wnt signaling
-
Lancaster MA, Gleeson JG. 2010. Cystic kidney disease: the role of Wnt signaling. Trends Mol. Med. 16:349-360.
-
(2010)
Trends Mol. Med
, vol.16
, pp. 349-360
-
-
Lancaster, M.A.1
Gleeson, J.G.2
-
14
-
-
7244229604
-
Distinct molecular forms of β-catenin are targeted to adhesive or transcriptional complexes
-
Gottardi CJ, Gumbiner BM. 2004. Distinct molecular forms of β-catenin are targeted to adhesive or transcriptional complexes. J. Cell Biol. 167: 339-349.
-
(2004)
J. Cell Biol.
, vol.167
, pp. 339-349
-
-
Gottardi, C.J.1
Gumbiner, B.M.2
-
15
-
-
0031456158
-
Wnt signaling: a common theme in animal development
-
Cadigan KM, Nusse R. 1997. Wnt signaling: a common theme in animal development. Genes Dev. 11:3286-3305.
-
(1997)
Genes Dev.
, vol.11
, pp. 3286-3305
-
-
Cadigan, K.M.1
Nusse, R.2
-
16
-
-
0033034120
-
beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xeno-pus axis formation
-
U. S. A.
-
Liu C, Kato Y, Zhang Z, Do VM, Yankner BA, He X. 1999. beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xeno-pus axis formation. Proc. Natl. Acad. Sci. U. S. A. 96:6273-6278.
-
(1999)
Proc. Natl. Acad. Sci.
, vol.96
, pp. 6273-6278
-
-
Liu, C.1
Kato, Y.2
Zhang, Z.3
Do, V.M.4
Yankner, B.A.5
He, X.6
-
17
-
-
0037155691
-
Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
-
Liu C, Li Y, Semenov M, Han C, Baeg Tan G-HY, Zhang Z, Lin X, He X. 2002. Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 108:837-847.
-
(2002)
Cell
, vol.108
, pp. 837-847
-
-
Liu, C.1
Li, Y.2
Semenov, M.3
Han, C.4
Baeg Tan, G.H.Y.5
Zhang, Z.6
Lin, X.7
He, X.8
-
18
-
-
0030978351
-
beta-Catenin is a target for the ubiquitin-proteasome pathway
-
Aberle H, Bauer A, Stappert J, Kispert A, Kemler R. 1997. beta-Catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 16:3797-3804.
-
(1997)
EMBO J.
, vol.16
, pp. 3797-3804
-
-
Aberle, H.1
Bauer, A.2
Stappert, J.3
Kispert, A.4
Kemler, R.5
-
19
-
-
67650230896
-
Wnt/beta-catenin signaling: components, mechanisms, and diseases
-
MacDonald BT, Tamai K, He X. 2009. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev. Cell 17:9-26.
-
(2009)
Dev. Cell
, vol.17
, pp. 9-26
-
-
MacDonald, B.T.1
Tamai, K.2
He, X.3
-
20
-
-
73949093736
-
Regulation of Wnt/β-catenin signaling by protein kinases
-
Verheyen EM, Gottardi CJ. 2010. Regulation of Wnt/β-catenin signaling by protein kinases. Dev. Dyn. 239:34-44.
-
(2010)
Dev. Dyn
, vol.239
, pp. 34-44
-
-
Verheyen, E.M.1
Gottardi, C.J.2
-
21
-
-
77956300964
-
Beta-Catenin phosphorylated at serine 45 is spatially uncoupled from beta-catenin phosphorylated in the GSK3 domain: implications for signaling
-
doi:10.1371/journal.pone.0010184.
-
Maher MT, Mo R, Flozak AS, Peled ON, Gottardi CJ. 2010. Beta-Catenin phosphorylated at serine 45 is spatially uncoupled from beta-catenin phosphorylated in the GSK3 domain: implications for signaling. PLoS One 5:e10184. doi:10.1371/journal.pone.0010184.
-
(2010)
PLoS One
, vol.5
-
-
Maher, M.T.1
Mo, R.2
Flozak, A.S.3
Peled, O.N.4
Gottardi, C.J.5
-
22
-
-
79951826931
-
PIPKIgamma regulates beta-catenin transcriptional activity downstream of growth factor receptor signaling
-
Schramp M, Thapa N, Heck J, Anderson R. 2011. PIPKIgamma regulates beta-catenin transcriptional activity downstream of growth factor receptor signaling. Cancer Res. 71:1282-1291.
-
(2011)
Cancer Res
, vol.71
, pp. 1282-1291
-
-
Schramp, M.1
Thapa, N.2
Heck, J.3
Anderson, R.4
-
23
-
-
46149089742
-
Plasma membrane recruitment of dephosphorylated beta-catenin upon activation of the Wnt pathway
-
Hendriksen J, Jansen M, Brown CM, van der Velde H, van Ham M, Galjart N, Offerhaus GJ, Fagotto F, Fornerod M. 2008. Plasma membrane recruitment of dephosphorylated beta-catenin upon activation of the Wnt pathway. J. Cell Sci. 121:1793-1802.
-
(2008)
J. Cell Sci.
, vol.121
, pp. 1793-1802
-
-
Hendriksen, J.1
Jansen, M.2
Brown, C.M.3
van der Velde, H.4
van Ham, M.5
Galjart, N.6
Offerhaus, G.J.7
Fagotto, F.8
Fornerod, M.9
-
24
-
-
0036166297
-
Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin
-
Staal FJT, van Noort M, Strous GJ, Clevers HC. 2002. Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin. EMBO Rep. 3:63-68.
-
(2002)
EMBO Rep
, vol.3
, pp. 63-68
-
-
Staal, F.J.T.1
van Noort, M.2
Strous, G.J.3
Clevers, H.C.4
-
25
-
-
67749120363
-
Activity of the beta-catenin phosphodestruction complex at cell-cell contacts is enhanced by cadherin-based adhesion
-
Maher MT, Flozak AS, Stocker AM, Chenn A, Gottardi CJ. 2009. Activity of the beta-catenin phosphodestruction complex at cell-cell contacts is enhanced by cadherin-based adhesion. J. Cell Biol. 186:219-228.
-
(2009)
J. Cell Biol
, vol.186
, pp. 219-228
-
-
Maher, M.T.1
Flozak, A.S.2
Stocker, A.M.3
Chenn, A.4
Gottardi, C.J.5
-
26
-
-
51449094367
-
Wingless signalling alters the levels, subcellular distribution and dynamics of armadillo and E-cadherin in third instar larval wing imaginal discs
-
doi:10.1371/journal.pone.0002893.
-
Somorjai IML, Martinez-Arias A. 2008. Wingless signalling alters the levels, subcellular distribution and dynamics of armadillo and E-cadherin in third instar larval wing imaginal discs. PLoS One 3:e2893. doi:10.1371/journal.pone.0002893.
-
(2008)
PLoS One
, vol.3
-
-
Somorjai, I.M.L.1
Martinez-Arias, A.2
-
27
-
-
84887212494
-
Cadherin-bound beta-catenin feeds into the Wnt pathway upon adherens junctions dissociation: evidence for an intersection between beta-catenin pools
-
doi:10.1371/journal.pone.0004580.
-
Kam Y, Quaranta V. 2009. Cadherin-bound beta-catenin feeds into the Wnt pathway upon adherens junctions dissociation: evidence for an intersection between beta-catenin pools. PLoS One 4:e4580. doi:10.1371/journal.pone.0004580.
-
(2009)
PLoS One
, vol.4
-
-
Kam, Y.1
Quaranta, V.2
-
28
-
-
70449657727
-
EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-catenin from beta-catenin and transactivation of beta-catenin
-
Ji H, Wang J, Nika H, Hawke D, Keezer S, Ge Q, Fang B, Fang X, Fang D, Litchfield DW, Aldape K, Lu Z. 2009. EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-catenin from beta-catenin and transactivation of beta-catenin. Mol. Cell 36:547-559.
-
(2009)
Mol. Cell
, vol.36
, pp. 547-559
-
-
Ji, H.1
Wang, J.2
Nika, H.3
Hawke, D.4
Keezer, S.5
Ge, Q.6
Fang, B.7
Fang, X.8
Fang, D.9
Litchfield, D.W.10
Aldape, K.11
Lu, Z.12
-
29
-
-
80052338841
-
A positive role of cadherin in Wnt/beta-catenin signalling during epithelial-mesenchymal transition
-
doi:10.1371/journal.pone.0023899.
-
Howard S, Deroo T, Fujita Y, Itasaki N. 2011. A positive role of cadherin in Wnt/beta-catenin signalling during epithelial-mesenchymal transition. PLoS One 6:e23899. doi:10.1371/journal.pone.0023899.
-
(2011)
PLoS One
, vol.6
-
-
Howard, S.1
Deroo, T.2
Fujita, Y.3
Itasaki, N.4
-
30
-
-
33750459738
-
Catenins: keeping cells from getting their signals crossed
-
Perez-Moreno M, Fuchs E. 2006. Catenins: keeping cells from getting their signals crossed. Dev. Cell 11:601-612.
-
(2006)
Dev. Cell
, vol.11
, pp. 601-612
-
-
Perez-Moreno, M.1
Fuchs, E.2
-
32
-
-
78751704702
-
ARF6-mediated endocytic recycling impacts cell movement, cell division and lipid homeo-stasis
-
Schweitzer JK, Sedgwick AE, D'Souza-Schorey C. 2011. ARF6-mediated endocytic recycling impacts cell movement, cell division and lipid homeo-stasis. Semin. Cell Dev. Biol. 22:39-47.
-
(2011)
Semin. Cell Dev. Biol.
, vol.22
, pp. 39-47
-
-
Schweitzer, J.K.1
Sedgwick, A.E.2
D'Souza-Schorey, C.3
-
33
-
-
59149105836
-
ADP-ribosylation factor 6 regulates glioma cell invasion through the IQ-domain GTPase-activating protein 1-Rac1-mediated pathway
-
Hu B, Shi B, Jarzynka MJ, Yiin JJ, D'Souza-Schorey C, Cheng SY. 2009. ADP-ribosylation factor 6 regulates glioma cell invasion through the IQ-domain GTPase-activating protein 1-Rac1-mediated pathway. Cancer Res. 69:794-801.
-
(2009)
Cancer Res
, vol.69
, pp. 794-801
-
-
Hu, B.1
Shi, B.2
Jarzynka, M.J.3
Yiin, J.J.4
D'Souza-Schorey, C.5
Cheng, S.Y.6
-
34
-
-
65549106079
-
ADP-ribosylation factor 6 regulates tumorigenic and invasive properties in vivo
-
Muralidharan-Chari V, Hoover H, Clancy J, Schweitzer J, Suckow MA, Schroeder V, Castellino FJ, Schorey JS, D'Souza-Schorey C. 2009. ADP-ribosylation factor 6 regulates tumorigenic and invasive properties in vivo. Cancer Res. 69:2201-2209.
-
(2009)
Cancer Res
, vol.69
, pp. 2201-2209
-
-
Muralidharan-Chari, V.1
Hoover, H.2
Clancy, J.3
Schweitzer, J.4
Suckow, M.A.5
Schroeder, V.6
Castellino, F.J.7
Schorey, J.S.8
D'Souza-Schorey, C.9
-
35
-
-
0035801516
-
An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration
-
Palacios F, Price L, Schweitzer J, Collard JG, D'Souza-Schorey C. 2001. An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration. EMBO J. 20:4973-4986.
-
(2001)
EMBO J
, vol.20
, pp. 4973-4986
-
-
Palacios, F.1
Price, L.2
Schweitzer, J.3
Collard, J.G.4
D'Souza-Schorey, C.5
-
36
-
-
11844276068
-
Disassembling adherens junctions: breaking up is hard to do
-
D'Souza-Schorey C. 2005. Disassembling adherens junctions: breaking up is hard to do. Trends Cell Biol. 15:19-26.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 19-26
-
-
D'Souza-Schorey, C.1
-
37
-
-
33746097786
-
GEP100/BRAG2: activator of ADP-ribosylation factor 6 for regulation of cell adhesion and actin cytoskeleton via E-cadherin and alpha-catenin
-
U. S. A.
-
Hiroi T, Someya A, Thompson W, Moss J, Vaughan M. 2006. GEP100/BRAG2: activator of ADP-ribosylation factor 6 for regulation of cell adhesion and actin cytoskeleton via E-cadherin and alpha-catenin. Proc. Natl. Acad. Sci. U. S. A. 103:10672-10677.
-
(2006)
Proc. Natl. Acad. Sci.
, vol.103
, pp. 10672-10677
-
-
Hiroi, T.1
Someya, A.2
Thompson, W.3
Moss, J.4
Vaughan, M.5
-
38
-
-
40949109641
-
Clathrin dependent endocytosis of E-cadherin is regulated by the Arf6GAP isoform SMAP1
-
Kon S, Tanabe K, Watanabe T, Sabe H, Satake M. 2008. Clathrin dependent endocytosis of E-cadherin is regulated by the Arf6GAP isoform SMAP1. Exp. Cell Res. 314:1415-1428.
-
(2008)
Exp. Cell Res
, vol.314
, pp. 1415-1428
-
-
Kon, S.1
Tanabe, K.2
Watanabe, T.3
Sabe, H.4
Satake, M.5
-
39
-
-
0037178797
-
Localization and activation of the ARF6 GTPase during cleavage furrow ingression and cytokinesis
-
Schweitzer JK, D'Souza-Schorey C. 2002. Localization and activation of the ARF6 GTPase during cleavage furrow ingression and cytokinesis. J. Biol. Chem. 277:27210-27216.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 27210-27216
-
-
Schweitzer, J.K.1
D'Souza-Schorey, C.2
-
40
-
-
34247254459
-
ARF6-dependent activation of ERK and Rac1 modulates epithelial tubule development
-
Tushir J, D'Souza-Schorey C. 2007. ARF6-dependent activation of ERK and Rac1 modulates epithelial tubule development. EMBO J. 26:1806-1819.
-
(2007)
EMBO J
, vol.26
, pp. 1806-1819
-
-
Tushir, J.1
D'Souza-Schorey, C.2
-
41
-
-
84870574916
-
Establishing epithelial glandular polarity: interlinked roles for ARF6, Rac1, and the matrix microenvironment
-
Monteleon CL, Sedgwick A, Hartsell A, Dai M, Whittington C, Voytik-Harbin S, D'Souza-Schorey C. 2012. Establishing epithelial glandular polarity: interlinked roles for ARF6, Rac1, and the matrix microenvironment. Mol. Biol. Cell 23:4495-4505.
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 4495-4505
-
-
Monteleon, C.L.1
Sedgwick, A.2
Hartsell, A.3
Dai, M.4
Whittington, C.5
Voytik-Harbin, S.6
D'Souza-Schorey, C.7
-
42
-
-
0037737726
-
Wnt proteins are lipid-modified and can act as stem cell growth factors
-
Willert K, Brown JD, Danenberg E, Duncan AW, Weissman IL, Reya T, Yates JR, Nusse R. 2003. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 423:448-452.
-
(2003)
Nature
, vol.423
, pp. 448-452
-
-
Willert, K.1
Brown, J.D.2
Danenberg, E.3
Duncan, A.W.4
Weissman, I.L.5
Reya, T.6
Yates, J.R.7
Nusse, R.8
-
43
-
-
77954183800
-
Unregulated ARF6 activation in epithelial cysts generates hyperactive signaling endosomes and disrupts morphogenesis
-
Tushir JS, Clancy J, Warren A, Wrobel C, Brugge JS, D'Souza-Schorey C. 2010. Unregulated ARF6 activation in epithelial cysts generates hyperactive signaling endosomes and disrupts morphogenesis. Mol. Biol. Cell 21:2355-2366.
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 2355-2366
-
-
Tushir, J.S.1
Clancy, J.2
Warren, A.3
Wrobel, C.4
Brugge, J.S.5
D'Souza-Schorey, C.6
-
44
-
-
41949105179
-
Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling
-
Wu X, Tu X, Joeng KS, Hilton MJ, Williams DA, Long F. 2008. Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling. Cell 133:340-353.
-
(2008)
Cell
, vol.133
, pp. 340-353
-
-
Wu, X.1
Tu, X.2
Joeng, K.S.3
Hilton, M.J.4
Williams, D.A.5
Long, F.6
-
46
-
-
34249301021
-
EGF receptor is involved in WNT3a-mediated proliferation and motility of NIH3T3 cells via ERK pathway activation
-
Kim S-E, Choi K-Y. 2007. EGF receptor is involved in WNT3a-mediated proliferation and motility of NIH3T3 cells via ERK pathway activation. Cell. Signal. 19:1554-1564.
-
(2007)
Cell. Signal.
, vol.19
, pp. 1554-1564
-
-
Kim, S.E.1
Choi, K.Y.2
-
47
-
-
33748702122
-
The GSK-3 inhibitor BIO promotes proliferation in mammalian cardiomyocytes
-
Tseng A-S, Engel FB, Keating MT. 2006. The GSK-3 inhibitor BIO promotes proliferation in mammalian cardiomyocytes. Chem. Biol. 13: 957-963.
-
(2006)
Chem. Biol.
, vol.13
, pp. 957-963
-
-
Tseng, A.S.1
Engel, F.B.2
Keating, M.T.3
-
48
-
-
0029166667
-
A synthetic inhibitor of the mitogen-activated protein kinase cascade
-
U. S. A.
-
Dudley DT, Pang L, Decker SJ, Bridges AJ, Saltiel AR. 1995. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. U. S. A. 92:7686-7689.
-
(1995)
Proc. Natl. Acad. Sci.
, vol.92
, pp. 7686-7689
-
-
Dudley, D.T.1
Pang, L.2
Decker, S.J.3
Bridges, A.J.4
Saltiel, A.R.5
-
49
-
-
33646892646
-
Dynasore, a cell-permeable inhibitor of dynamin
-
Macia E, Ehrlich M, Massol R, Boucrot E, Brunner C, Kirchhausen T. 2006. Dynasore, a cell-permeable inhibitor of dynamin. Dev. Cell 10:839-850.
-
(2006)
Dev. Cell.
, vol.10
, pp. 839-850
-
-
Macia, E.1
Ehrlich, M.2
Massol, R.3
Boucrot, E.4
Brunner, C.5
Kirchhausen, T.6
-
50
-
-
84860449381
-
Receptor tyrosine kinases activate canonical WNT/β-catenin signaling via MAP kinase/LRP6 pathway and direct beta-catenin phosphorylation
-
doi:10.1371/journal.pone.0035826.
-
Krejci P, Aklian A, Kaucka M, Sevcikova E, Prochazkova J, Masek JK, Mikolka P, Pospisilova T, Spoustova T, Weis M, Paznekas WA, Wolf JH, Gutkind JS, Wilcox WR, Kozubik A, Jabs EW, Bryja V, Salazar L, Vesela I, Balek L. 2012. Receptor tyrosine kinases activate canonical WNT/β-catenin signaling via MAP kinase/LRP6 pathway and direct beta-catenin phosphorylation. PLoS One 7:e35826. doi:10.1371/journal.pone.0035826.
-
(2012)
PLoS One
, vol.7
-
-
Krejci, P.1
Aklian, A.2
Kaucka, M.3
Sevcikova, E.4
Prochazkova, J.5
Masek, J.K.6
Mikolka, P.7
Pospisilova, T.8
Spoustova, T.9
Weis, M.10
Paznekas, W.A.11
Wolf, J.H.12
Gutkind, J.S.13
Wilcox, W.R.14
Kozubik, A.15
Jabs, E.W.16
Bryja, V.17
Salazar, L.18
Vesela, I.19
Balek, L.20
more..
-
51
-
-
77954685213
-
Regulation of Lrp6 phosphorylation
-
Niehrs C, Shen J. 2010. Regulation of Lrp6 phosphorylation. Cell. Mol. Life Sci. 67:2551-2562.
-
(2010)
Cell. Mol. Life Sci.
, vol.67
, pp. 2551-2562
-
-
Niehrs, C.1
Shen, J.2
-
52
-
-
25444443688
-
Modelling glandular epithelial cancers in three-dimensional cultures
-
Debnath J, Brugge JS. 2005. Modelling glandular epithelial cancers in three-dimensional cultures. Nat. Rev. Cancer 5:675-688.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 675-688
-
-
Debnath, J.1
Brugge, J.S.2
-
53
-
-
79955479314
-
Wnt/beta-catenin activation promotes prostate tumor progression in a mouse model
-
Yu X, Wang Y, DeGraffDJ, Wills ML, Matusik RJ. 2011. Wnt/beta-catenin activation promotes prostate tumor progression in a mouse model. Oncogene 30:1868-1879.
-
(2011)
Oncogene
, vol.30
, pp. 1868-1879
-
-
Yu, X.1
Wang, Y.2
DeGraff, D.J.3
Wills, M.L.4
Matusik, R.J.5
-
54
-
-
84863352083
-
Activation status of Wnt/ss-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouse
-
doi:10.1371/journal.pone.0033421.
-
Khalil S, Tan GA, Giri DD, Zhou XK, Howe LR. 2012. Activation status of Wnt/ss-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouse. PLoS One 7:e33421. doi:10.1371/journal.pone.0033421.
-
(2012)
PLoS One
, vol.7
-
-
Khalil, S.1
Tan, G.A.2
Giri, D.D.3
Zhou, X.K.4
Howe, L.R.5
-
55
-
-
78651401020
-
beta-Catenin activation synergizes with PTEN loss to cause bladder cancer formation
-
Ahmad I, Morton JP, Singh LB, Radulescu SM, Ridgway RA, Patel S, Woodgett J, Winton DJ, Taketo MM, Wu XR, Leung HY, Sansom OJ. 2011. beta-Catenin activation synergizes with PTEN loss to cause bladder cancer formation. Oncogene 30:178-189.
-
(2011)
Oncogene
, vol.30
, pp. 178-189
-
-
Ahmad, I.1
Morton, J.P.2
Singh, L.B.3
Radulescu, S.M.4
Ridgway, R.A.5
Patel, S.6
Woodgett, J.7
Winton, D.J.8
Taketo, M.M.9
Wu, X.R.10
Leung, H.Y.11
Sansom, O.J.12
-
56
-
-
33646425568
-
Aberrant Wnt/beta-catenin signaling in pancreatic adenocarcinoma
-
Zeng G, Germinaro M, Micsenyi A, Monga NK, Bell A, Sood A, Malhotra V, Sood N, Midda V, Monga DK, Kokkinakis DM, Monga SP. 2006. Aberrant Wnt/beta-catenin signaling in pancreatic adenocarcinoma. Neoplasia 8:279-289.
-
(2006)
Neoplasia
, vol.8
, pp. 279-289
-
-
Zeng, G.1
Germinaro, M.2
Micsenyi, A.3
Monga, N.K.4
Bell, A.5
Sood, A.6
Malhotra, V.7
Sood, N.8
Midda, V.9
Monga, D.K.10
Kokkinakis, D.M.11
Monga, S.P.12
-
57
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
He T-C, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, Morin PJ, Vogelstein B, Kinzler KW. 1998. Identification of c-MYC as a target of the APC pathway. Science 281:1509-1512.
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
Hermeking, H.4
Zawel, L.5
da Costa, L.T.6
Morin, P.J.7
Vogelstein, B.8
Kinzler, K.W.9
-
58
-
-
37549048249
-
The BCL-2 protein family: opposing activities that mediate cell death
-
Youle RJ, Strasser A. 2008. The BCL-2 protein family: opposing activities that mediate cell death. Nat. Rev. Mol. Cell Biol. 9:47-59.
-
(2008)
Nat. Rev. Mol. Cell Biol
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
59
-
-
70349932747
-
Towards an integrated view of Wnt signaling in development
-
van Amerongen R, Nusse R. 2009. Towards an integrated view of Wnt signaling in development. Development 136:3205-3214.
-
(2009)
Development
, vol.136
, pp. 3205-3214
-
-
van Amerongen, R.1
Nusse, R.2
-
60
-
-
0037534466
-
Modulation of Rac1 and ARF6 activation during epithelial cell scattering
-
Palacios F, D'Souza-Schorey C. 2003. Modulation of Rac1 and ARF6 activation during epithelial cell scattering. J. Biol. Chem. 278:17395-17400.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17395-17400
-
-
Palacios, F.1
D'Souza-Schorey, C.2
-
61
-
-
70449552889
-
Endosomes: a legitimate platform for the signaling train
-
U. S. A.
-
Murphy JE, Padilla BE, Hasdemir B, Cottrell GS, Bunnett NW. 2009. Endosomes: a legitimate platform for the signaling train. Proc. Natl. Acad. Sci. U. S. A. 106:17615-17622.
-
(2009)
Proc. Natl. Acad. Sci.
, vol.106
, pp. 17615-17622
-
-
Murphy, J.E.1
Padilla, B.E.2
Hasdemir, B.3
Cottrell, G.S.4
Bunnett, N.W.5
-
62
-
-
67349103762
-
Signaling from endosomes: location makes a difference
-
Sadowski L, Pilecka I, Miaczynska M. 2009. Signaling from endosomes: location makes a difference. Exp. Cell Res. 315:1601-1609.
-
(2009)
Exp. Cell Res.
, vol.315
, pp. 1601-1609
-
-
Sadowski, L.1
Pilecka, I.2
Miaczynska, M.3
-
63
-
-
6344248651
-
PKC controls HGF-dependent c-Met traffic, signalling and cell migration
-
Kermorgant S, Zicha D, Parker PJ. 2004. PKC controls HGF-dependent c-Met traffic, signalling and cell migration. EMBO J. 23:3721-3734.
-
(2004)
EMBO J
, vol.23
, pp. 3721-3734
-
-
Kermorgant, S.1
Zicha, D.2
Parker, P.J.3
-
64
-
-
33645732587
-
Internalization is required for proper Wingless signaling in Drosophila melanogaster
-
Seto ES, Bellen HJ. 2006. Internalization is required for proper Wingless signaling in Drosophila melanogaster. J. Cell Biol. 173:95-106.
-
(2006)
J. Cell Biol.
, vol.173
, pp. 95-106
-
-
Seto, E.S.1
Bellen, H.J.2
-
65
-
-
0036606805
-
When cell biology meets development: endocytic regulation of signaling pathways
-
Seto ES, Bellen HJ, Lloyd TE. 2002. When cell biology meets development: endocytic regulation of signaling pathways. Genes Dev. 16:1314-1336.
-
(2002)
Genes Dev
, vol.16
, pp. 1314-1336
-
-
Seto, E.S.1
Bellen, H.J.2
Lloyd, T.E.3
-
66
-
-
33746960721
-
A critical role for endocytosis in Wnt signaling
-
doi:10.1186/1471-2121-7-28.
-
Blitzer JT, Nusse R. 2006. A critical role for endocytosis in Wnt signaling. BMC Cell Biol. 7:28. doi:10.1186/1471-2121-7-28.
-
(2006)
BMC Cell Biol
, vol.7
, pp. 28
-
-
Blitzer, J.T.1
Nusse, R.2
-
67
-
-
0042696985
-
Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis
-
Reginato MJ, Mills KR, Paulus JK, Lynch DK, Sgroi DC, Debnath J, Muthuswamy SK, Brugge JS. 2003. Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis. Nat. Cell Biol. 5:733-740.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 733-740
-
-
Reginato, M.J.1
Mills, K.R.2
Paulus, J.K.3
Lynch, D.K.4
Sgroi, D.C.5
Debnath, J.6
Muthuswamy, S.K.7
Brugge, J.S.8
-
68
-
-
33750053855
-
Casein kinase 2 (CK2) increases survivin expression via enhanced beta-catenin-T cell factor/lymphoid enhancer binding factor-dependent transcription
-
U. S. A.
-
Tapia JC, Torres VA, Rodriguez DA, Leyton L, Quest AFG. 2006. Casein kinase 2 (CK2) increases survivin expression via enhanced beta-catenin-T cell factor/lymphoid enhancer binding factor-dependent transcription. Proc. Natl. Acad. Sci. U. S. A. 103:15079-15084.
-
(2006)
Proc. Natl. Acad. Sci.
, vol.103
, pp. 15079-15084
-
-
Tapia, J.C.1
Torres, V.A.2
Rodriguez, D.A.3
Leyton, L.4
Quest, A.F.G.5
-
69
-
-
0037020196
-
The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini
-
Debnath J, Mills KR, Collins NL, Reginato MJ, Muthuswamy SK, Brugge JS. 2002. The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. Cell 111:29-40.
-
(2002)
Cell
, vol.111
, pp. 29-40
-
-
Debnath, J.1
Mills, K.R.2
Collins, N.L.3
Reginato, M.J.4
Muthuswamy, S.K.5
Brugge, J.S.6
-
70
-
-
0036528247
-
Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma
-
Weeraratna AT, Jiang Y, Hostetter G, Rosenblatt K, Duray P, Bittner M, Trent JM. 2002. Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma. Cancer Cell 1:279-288.
-
(2002)
Cancer Cell
, vol.1
, pp. 279-288
-
-
Weeraratna, A.T.1
Jiang, Y.2
Hostetter, G.3
Rosenblatt, K.4
Duray, P.5
Bittner, M.6
Trent, J.M.7
-
71
-
-
33646241997
-
Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context
-
doi:10.1371/journal.pbio.0040115.
-
Mikels AJ, Nusse R. 2006. Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol. 4:e115. doi:10.1371/journal.pbio.0040115.
-
(2006)
PLoS Biol
, vol.4
-
-
Mikels, A.J.1
Nusse, R.2
-
72
-
-
59149105271
-
Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formation
-
Cha SW, Tadjuidje E, Tao Q, Wylie C, Heasman J. 2008. Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formation. Development 135:3719-3729.
-
(2008)
Development
, vol.135
, pp. 3719-3729
-
-
Cha, S.W.1
Tadjuidje, E.2
Tao, Q.3
Wylie, C.4
Heasman, J.5
-
73
-
-
84875168586
-
The small GTPase ARF6 stimulates beta-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis
-
doi:10.1126/scisignal.2003398.
-
Grossmann AH, Yoo JH, Clancy J, Sorensen LK, Sedgwick A, Tong Z, Ostanin K, Rogers A, Grossmann KF, Tripp SR, Thomas KR, D'Souza-Schorey C, Odelberg SJ, Li DY. 2013. The small GTPase ARF6 stimulates beta-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis. Sci. Signal. 6:ra14. doi:10.1126/scisignal.2003398.
-
(2013)
Sci. Signal.
, vol.6
-
-
Grossmann, A.H.1
Yoo, J.H.2
Clancy, J.3
Sorensen, L.K.4
Sedgwick, A.5
Tong, Z.6
Ostanin, K.7
Rogers, A.8
Grossmann, K.F.9
Tripp, S.R.10
Thomas, K.R.11
D'Souza-Schorey, C.12
Odelberg, S.J.13
Li, D.Y.14
-
74
-
-
37749041462
-
GEP100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion
-
Morishige M, Hashimoto S, Ogawa E, Toda Y, Kotani H, Hirose M, Wei S, Hashimoto A, Yamada A, Yano H, Mazaki Y, Kodama H, Nio Y, Manabe T, Wada H, Kobayashi H, Sabe H. 2008. GEP100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion. Nat. Cell Biol. 10:85-92.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 85-92
-
-
Morishige, M.1
Hashimoto, S.2
Ogawa, E.3
Toda, Y.4
Kotani, H.5
Hirose, M.6
Wei, S.7
Hashimoto, A.8
Yamada, A.9
Yano, H.10
Mazaki, Y.11
Kodama, H.12
Nio, Y.13
Manabe, T.14
Wada, H.15
Kobayashi, H.16
Sabe, H.17
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