Ku70 and non-homologous end joining protect testicular cells from dna damage

Journal of Cell Science

Volumn 126, Issue 14, 2013, Pages 3095-3104

  Ahmed, Emad A ^a   Sfeir, Agnel ^b   Takai, Hiroyuki ^b   Scherthan, Harry ^a,c  

^a Institut fur Radiobiologie der Bundeswehr   (Germany)

^b ROCKEFELLER UNIVERSITY   (United States)

^c MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

Author keywords

Bouquet formation; DNA damage; Ku70; Meiosis; Mid preleptotene; NHEJ; Rap1; Recombination; Sertoli cell; Shelterin; Spermatogenesis; Telomere attachment

Indexed keywords

DNA; DOUBLE STRANDED DNA; HISTONE H2AX; KU ANTIGEN; RAP1 PROTEIN; SPO11 PROTEIN;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CHROMOSOME PAIRING; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DNA DAMAGE; DNA END JOINING REPAIR; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; G1 PHASE CELL CYCLE CHECKPOINT; HOMOLOGOUS RECOMBINATION; M PHASE CELL CYCLE CHECKPOINT; MEIOTIC PROPHASE I; METAPHASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SEMINIFEROUS TUBULE; SERTOLI CELL; SPERMATOCYTE; SPERMATOGENESIS; SPERMATOGONIUM; TELOMERE; TESTIS CELL; TESTIS SIZE;

BOUQUET FORMATION; DNA DAMAGE; KU70; MEIOSIS; MID-PRELEPTOTENE; NHEJ; RAP1; RECOMBINATION; SERTOLI CELL; SHELTERIN; SPERMATOGENESIS; TELOMERE ATTACHMENT;

ANIMALS; ANTIGENS, NUCLEAR; APOPTOSIS; CELL CYCLE; CELLS, CULTURED; DNA DAMAGE; DNA REPAIR; DNA, RECOMBINANT; DNA-BINDING PROTEINS; MALE; MEIOSIS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORGAN SIZE; RAP1 GTP-BINDING PROTEINS; RECOMBINATION, GENETIC; SPERMATOGENESIS; TESTIS;

EID: 84880659005     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.122788     Document Type: Article

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