메뉴 건너뛰기




Volumn 49, Issue 3, 2013, Pages 523-530

Protective Role of Astrocytic Leptin Signaling Against Excitotoxicity

Author keywords

Astrocyte; Cytotoxicity; Epilepsy; Glutamate; Leptin; ObR

Indexed keywords

ADENOSINE TRIPHOSPHATE; DIAZEPAM; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMIC ACID; LEPTIN; LEPTIN RECEPTOR; OBRA PROTEIN; OBRB PROTEIN; PILOCARPINE; PROTEIN; UNCLASSIFIED DRUG; CONVULSANT AGENT; LEPTIN RECEPTOR, MOUSE; NERVE PROTEIN; NEUROTOXIN;

EID: 84880629801     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-012-9924-0     Document Type: Article
Times cited : (22)

References (40)
  • 1
    • 77955745277 scopus 로고    scopus 로고
    • Glial cells in neuronal network function
    • 20603358 10.1098/rstb.2009.0313
    • Araque A, Navarrete M (2010) Glial cells in neuronal network function. Philos Trans R Soc Lond B Biol Sci 365:2375-2381
    • (2010) Philos Trans R Soc Lond B Biol Sci , vol.365 , pp. 2375-2381
    • Araque, A.1    Navarrete, M.2
  • 2
    • 0029864416 scopus 로고    scopus 로고
    • Leptin enters the brain by a saturable system independent of insulin
    • 8801538 10.1016/0196-9781(96)00025-3 1:CAS:528:DyaK28XhvFOlt7Y%3D
    • Banks WA, Kastin AJ, Huang W, Jaspan JB, Maness LM (1996) Leptin enters the brain by a saturable system independent of insulin. Peptides 17:305-311
    • (1996) Peptides , vol.17 , pp. 305-311
    • Banks, W.A.1    Kastin, A.J.2    Huang, W.3    Jaspan, J.B.4    Maness, L.M.5
  • 3
    • 0031436148 scopus 로고    scopus 로고
    • Divergent signaling capacities of the long and short isoforms of the leptin receptor
    • 9405487 10.1074/jbc.272.51.32686
    • Bjørbæk C, Uotani S, da Silva B, Flier JS (1997) Divergent signaling capacities of the long and short isoforms of the leptin receptor. J Biol Chem 272:32686-32695
    • (1997) J Biol Chem , vol.272 , pp. 32686-32695
    • Bjørbæk, C.1    Uotani, S.2    Da Silva, B.3    Flier, J.S.4
  • 4
    • 1842536210 scopus 로고    scopus 로고
    • Trophic action of leptin on hypothalamic neurons that regulate feeding
    • 15064420 10.1126/science.1095004 1:CAS:528:DC%2BD2cXis1ansb4%3D
    • Bouret SG, Draper SJ, Simerly RB (2004) Trophic action of leptin on hypothalamic neurons that regulate feeding. Science 304:108-110
    • (2004) Science , vol.304 , pp. 108-110
    • Bouret, S.G.1    Draper, S.J.2    Simerly, R.B.3
  • 6
    • 0025124371 scopus 로고
    • Effects of MK-801 on glutamate-induced swelling of astrocytes in primary cell culture
    • 1969495 10.1002/jnr.490250111 1:CAS:528:DyaK3cXpt1Chtw%3D%3D
    • Chan PH, Chu L, Chen S (1990) Effects of MK-801 on glutamate-induced swelling of astrocytes in primary cell culture. J Neurosci Res 25:87-93
    • (1990) J Neurosci Res , vol.25 , pp. 87-93
    • Chan, P.H.1    Chu, L.2    Chen, S.3
  • 7
    • 0033822531 scopus 로고    scopus 로고
    • Gliotoxic action of glutamate on cultured astrocytes
    • 10987836 10.1046/j.1471-4159.2000.0751557.x 1:CAS:528: DC%2BD3cXmslGlt70%3D
    • Chen CJ, Liao SL, Kuo JS (2000) Gliotoxic action of glutamate on cultured astrocytes. J Neurochem 75:1557-1565
    • (2000) J Neurochem , vol.75 , pp. 1557-1565
    • Chen, C.J.1    Liao, S.L.2    Kuo, J.S.3
  • 8
    • 38349143059 scopus 로고    scopus 로고
    • Leptin-mediated cell survival signaling in hippocampal neurons mediated by JAK STAT3 and mitochondrial stabilization
    • 17993459 10.1074/jbc.M703753200 1:CAS:528:DC%2BD1cXks1Ciug%3D%3D
    • Guo Z, Jiang H, Xu X, Duan W, Mattson MP (2008) Leptin-mediated cell survival signaling in hippocampal neurons mediated by JAK STAT3 and mitochondrial stabilization. J Biol Chem 283:1754-1763
    • (2008) J Biol Chem , vol.283 , pp. 1754-1763
    • Guo, Z.1    Jiang, H.2    Xu, X.3    Duan, W.4    Mattson, M.P.5
  • 9
    • 68749119353 scopus 로고    scopus 로고
    • Tripartite synapses: Roles for astrocytic purines in the control of synaptic physiology and behavior
    • 19577581 10.1016/j.neuropharm.2009.06.031 1:CAS:528:DC%2BD1MXhtVeis73I
    • Halassa MM, Fellin T, Haydon PG (2009) Tripartite synapses: roles for astrocytic purines in the control of synaptic physiology and behavior. Neuropharmacology 57:343-346
    • (2009) Neuropharmacology , vol.57 , pp. 343-346
    • Halassa, M.M.1    Fellin, T.2    Haydon, P.G.3
  • 10
    • 8844248622 scopus 로고    scopus 로고
    • Regional difference of glutamate-induced swelling in cultured rat brain astrocytes
    • 15556169 10.1016/j.lfs.2004.07.016 1:CAS:528:DC%2BD2cXhtVWjsLvK
    • Han BC, Koh SB, Lee EY, Seong YH (2004) Regional difference of glutamate-induced swelling in cultured rat brain astrocytes. Life Sci 76:573-583
    • (2004) Life Sci , vol.76 , pp. 573-583
    • Han, B.C.1    Koh, S.B.2    Lee, E.Y.3    Seong, Y.H.4
  • 11
    • 33745873475 scopus 로고    scopus 로고
    • Astrocyte control of synaptic transmission and neurovascular coupling
    • 16816144 10.1152/physrev.00049.2005 1:CAS:528:DC%2BD28XnsFGgtbY%3D
    • Haydon PG, Carmignoto G (2006) Astrocyte control of synaptic transmission and neurovascular coupling. Physiol Rev 86:1009-1031
    • (2006) Physiol Rev , vol.86 , pp. 1009-1031
    • Haydon, P.G.1    Carmignoto, G.2
  • 12
    • 74149086504 scopus 로고    scopus 로고
    • The Cdk5/p35 kinases modulate leptin-induced STAT3 signaling
    • 19156541 10.1007/s12031-008-9174-3 1:CAS:528:DC%2BD1MXhtFaksbvP
    • He Y, Kastin AJ, Hsuchou H, Pan W (2009) The Cdk5/p35 kinases modulate leptin-induced STAT3 signaling. J Mol Neurosci 39:49-58
    • (2009) J Mol Neurosci , vol.39 , pp. 49-58
    • He, Y.1    Kastin, A.J.2    Hsuchou, H.3    Pan, W.4
  • 15
    • 70449687899 scopus 로고    scopus 로고
    • Leptin receptor mRNA in rat brain astrocytes
    • 19747514 10.1016/j.peptides.2009.08.023 1:CAS:528:DC%2BD1MXhsVKntL3F
    • Hsuchou H, Pan W, Barnes MJ, Kastin AJ (2009b) Leptin receptor mRNA in rat brain astrocytes. Peptides 30:2275-2280
    • (2009) Peptides , vol.30 , pp. 2275-2280
    • Hsuchou, H.1    Pan, W.2    Barnes, M.J.3    Kastin, A.J.4
  • 16
    • 0035211890 scopus 로고    scopus 로고
    • The role of cytokines and growth factors in seizures and their sequelae
    • 11124444 10.1016/S0301-0082(00)00022-8 1:CAS:528:DC%2BD3cXovFWjsrc%3D
    • Jankowsky JL, Patterson PH (2001) The role of cytokines and growth factors in seizures and their sequelae. Prog Neurobiol 63:125-149
    • (2001) Prog Neurobiol , vol.63 , pp. 125-149
    • Jankowsky, J.L.1    Patterson, P.H.2
  • 17
    • 0034640450 scopus 로고    scopus 로고
    • Rapid increase in immunoreactivity to GFAP in astrocytes in vitro induced by acidic pH is mediated by calcium influx and calpain i
    • 10802029 10.1016/S0006-8993(00)02180-6 1:CAS:528:DC%2BD3cXivVGgs74%3D
    • Lee YB, Du S, Rhim H, Lee EB, Markelonis GJ, Oh TH (2000) Rapid increase in immunoreactivity to GFAP in astrocytes in vitro induced by acidic pH is mediated by calcium influx and calpain I. Brain Res 864:220-229
    • (2000) Brain Res , vol.864 , pp. 220-229
    • Lee, Y.B.1    Du, S.2    Rhim, H.3    Lee, E.B.4    Markelonis, G.J.5    Oh, T.H.6
  • 18
    • 77952322222 scopus 로고    scopus 로고
    • The proconvulsant effects of leptin on glutamate receptor-mediated seizures in mice
    • 20152888 10.1016/j.brainresbull.2010.02.003 1:CAS:528: DC%2BC3cXlsFaisr8%3D
    • Lynch JJ III, Shek EW, Castagne V, Mittelstadt SW (2010) The proconvulsant effects of leptin on glutamate receptor-mediated seizures in mice. Brain Res Bull 82:99-103
    • (2010) Brain Res Bull , vol.82 , pp. 99-103
    • Lynch III, J.J.1    Shek, E.W.2    Castagne, V.3    Mittelstadt, S.W.4
  • 19
    • 0035947033 scopus 로고    scopus 로고
    • In vitro demonstration of a saturable transport system for leptin across the blood-brain barrier
    • 11411806 10.1016/S0024-3205(01)01093-1 1:CAS:528:DC%2BD3MXktFOqtbc%3D
    • Maresh GA, Maness LM, Zadina JE, Kastin AJ (2001) In vitro demonstration of a saturable transport system for leptin across the blood-brain barrier. Life Sci 69:67-73
    • (2001) Life Sci , vol.69 , pp. 67-73
    • Maresh, G.A.1    Maness, L.M.2    Zadina, J.E.3    Kastin, A.J.4
  • 20
    • 0034713744 scopus 로고    scopus 로고
    • The regulation of leptin gene expression in the C6 glioblastoma cell line
    • 10940488 10.1016/S0303-7207(00)00259-8 1:CAS:528:DC%2BD3cXlsFCjsL4%3D
    • Morash B, Johnstone J, Leopold C, Li A, Murphy P, Ur E, Wilkinson M (2000) The regulation of leptin gene expression in the C6 glioblastoma cell line. Mol Cell Endocrinol 165:97-105
    • (2000) Mol Cell Endocrinol , vol.165 , pp. 97-105
    • Morash, B.1    Johnstone, J.2    Leopold, C.3    Li, A.4    Murphy, P.5    Ur, E.6    Wilkinson, M.7
  • 21
    • 0141533205 scopus 로고    scopus 로고
    • New roles for astrocytes: Redefining the functional architecture of the brain
    • 14522144 10.1016/j.tins.2003.08.008 1:CAS:528:DC%2BD3sXns1Cgtbc%3D
    • Nedergaard M, Ransom B, Goldman SA (2003) New roles for astrocytes: redefining the functional architecture of the brain. Trends Neurosci 26:523-530
    • (2003) Trends Neurosci , vol.26 , pp. 523-530
    • Nedergaard, M.1    Ransom, B.2    Goldman, S.A.3
  • 23
    • 44249114043 scopus 로고    scopus 로고
    • Astrocyte leptin receptor (ObR) and leptin transport in adult-onset obese mice
    • 18292187 10.1210/en.2007-1673 1:CAS:528:DC%2BD1cXms1entrc%3D
    • Pan W, Hsuchou H, He Y, Sakharkar A, Cain C, Yu C, Kastin AJ (2008) Astrocyte leptin receptor (ObR) and leptin transport in adult-onset obese mice. Endocrinology 149:2798-2806
    • (2008) Endocrinology , vol.149 , pp. 2798-2806
    • Pan, W.1    Hsuchou, H.2    He, Y.3    Sakharkar, A.4    Cain, C.5    Yu, C.6    Kastin, A.J.7
  • 26
    • 0030273727 scopus 로고    scopus 로고
    • New views on synapse-glia interactions
    • 8937825 10.1016/S0959-4388(96)80093-6 1:CAS:528:DyaK28XntVWrtrs%3D
    • Pfrieger FW, Barres BA (1996) New views on synapse-glia interactions. Curr Opin Neurobiol 6:615-621
    • (1996) Curr Opin Neurobiol , vol.6 , pp. 615-621
    • Pfrieger, F.W.1    Barres, B.A.2
  • 27
    • 0015526303 scopus 로고
    • Epileptiform activity and neural plasticity in limbic structures
    • 4641271 10.1016/0006-8993(72)90268-5 1:STN:280:DyaE3s%2Fmt1Wktw%3D%3D
    • Racine RJ, Gartner JG, Burnham WM (1972) Epileptiform activity and neural plasticity in limbic structures. Brain Res 47:262-268
    • (1972) Brain Res , vol.47 , pp. 262-268
    • Racine, R.J.1    Gartner, J.G.2    Burnham, W.M.3
  • 29
    • 0028988978 scopus 로고
    • D-serine, an endogenous synaptic modulator: Localization to astrocytes and glutamate-stimulated release
    • 7732010 10.1073/pnas.92.9.3948 1:CAS:528:DyaK2MXlsVSks7k%3D
    • Schell MJ, Molliver ME, Snyder SH (1995) d-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release. Proc Natl Acad Sci U S A 92:3948-3952
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 3948-3952
    • Schell, M.J.1    Molliver, M.E.2    Snyder, S.H.3
  • 30
    • 0027083504 scopus 로고
    • Mechanisms of glial swelling induced by glutamate
    • 1363532 10.1139/y92-280 1:CAS:528:DyaK3sXjtlCgtA%3D%3D
    • Schneider GH, Baethmann A, Kempski O (1992) Mechanisms of glial swelling induced by glutamate. Can J Physiol Pharmacol 70(Suppl):S334-S343
    • (1992) Can J Physiol Pharmacol , vol.70 , Issue.SUPPL.
    • Schneider, G.H.1    Baethmann, A.2    Kempski, O.3
  • 31
    • 0037115192 scopus 로고    scopus 로고
    • Leptin inhibits epileptiform-like activity in rat hippocampal neurones via PI 3-kinase-driven activation of BK channels
    • 12482897 10.1113/jphysiol.2002.029488 1:CAS:528:DC%2BD3sXpvV2rtg%3D%3D
    • Shanley LJ, O'Malley D, Irving AJ, Ashford ML, Harvey J (2002) Leptin inhibits epileptiform-like activity in rat hippocampal neurones via PI 3-kinase-driven activation of BK channels. J Physiol 545:933-944
    • (2002) J Physiol , vol.545 , pp. 933-944
    • Shanley, L.J.1    O'Malley, D.2    Irving, A.J.3    Ashford, M.L.4    Harvey, J.5
  • 32
    • 0031887488 scopus 로고    scopus 로고
    • Immunohistochemical localization of leptin receptor in the rat brain
    • 9535108 10.1016/S0304-3940(98)00082-2 1:CAS:528:DyaK1cXhtlOhtLk%3D
    • Shioda S, Funahashi H, Nakajo S, Yada T, Maruta O, Nakai Y (1998) Immunohistochemical localization of leptin receptor in the rat brain. Neurosci Lett 243:41-44
    • (1998) Neurosci Lett , vol.243 , pp. 41-44
    • Shioda, S.1    Funahashi, H.2    Nakajo, S.3    Yada, T.4    Maruta, O.5    Nakai, Y.6
  • 33
    • 0036136618 scopus 로고    scopus 로고
    • Calcium oscillations in neocortical astrocytes under epileptiform conditions
    • 11748632 10.1002/neu.10019 1:CAS:528:DC%2BD38XlsVantw%3D%3D
    • Tashiro A, Goldberg J, Yuste R (2002) Calcium oscillations in neocortical astrocytes under epileptiform conditions. J Neurobiol 50:45-55
    • (2002) J Neurobiol , vol.50 , pp. 45-55
    • Tashiro, A.1    Goldberg, J.2    Yuste, R.3
  • 34
    • 77954451732 scopus 로고    scopus 로고
    • Unique leptin trafficking by a tailless receptor
    • 20223942 10.1096/fj.09-143487 1:CAS:528:DC%2BC3cXptV2ktLc%3D
    • Tu H, Hsuchou H, Kastin AJ, Wu X, Pan W (2010) Unique leptin trafficking by a tailless receptor. FASEB J 24:2281-2291
    • (2010) FASEB J , vol.24 , pp. 2281-2291
    • Tu, H.1    Hsuchou, H.2    Kastin, A.J.3    Wu, X.4    Pan, W.5
  • 35
    • 34249686134 scopus 로고    scopus 로고
    • Convergent trafficking pattern of leptin after endocytosis mediated by ObRa-ObRd
    • 17323382 10.1002/jcp.21020 1:CAS:528:DC%2BD2sXmtVWkuro%3D
    • Tu H, Pan W, Feucht L, Kastin AJ (2007) Convergent trafficking pattern of leptin after endocytosis mediated by ObRa-ObRd. J Cell Physiol 212:215-222
    • (2007) J Cell Physiol , vol.212 , pp. 215-222
    • Tu, H.1    Pan, W.2    Feucht, L.3    Kastin, A.J.4
  • 36
    • 0020545095 scopus 로고
    • Limbic seizures produced by pilocarpine in rats: Behavioural, electroencephalographic and neuropathological study
    • 6639740 10.1016/0166-4328(83)90136-5 1:CAS:528:DyaL3sXlvFaktbo%3D
    • Turski WA, Cavalheiro EA, Schwarz M, Czuczwar SJ, Kleinrok Z, Turski L (1983) Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study. Behav Brain Res 9:315-335
    • (1983) Behav Brain Res , vol.9 , pp. 315-335
    • Turski, W.A.1    Cavalheiro, E.A.2    Schwarz, M.3    Czuczwar, S.J.4    Kleinrok, Z.5    Turski, L.6
  • 37
    • 0024510191 scopus 로고
    • Review: Cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: A novel experimental model of intractable epilepsy
    • 2648633 10.1002/syn.890030207 1:CAS:528:DyaL1MXhslSqur0%3D
    • Turski L, Ikonomidou C, Turski WA, Bortolotto ZA, Cavalheiro EA (1989) Review: cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: a novel experimental model of intractable epilepsy. Synapse 3:154-171
    • (1989) Synapse , vol.3 , pp. 154-171
    • Turski, L.1    Ikonomidou, C.2    Turski, W.A.3    Bortolotto, Z.A.4    Cavalheiro, E.A.5
  • 39
    • 38149063843 scopus 로고    scopus 로고
    • Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents
    • 18097472 10.1172/JCI33009 1:CAS:528:DC%2BD1cXksFOktg%3D%3D
    • Xu L, Rensing N, Yang XF, Zhang HX, Thio LL, Rothman SM, Weisenfeld AE, Wong M, Yamada KA (2008) Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents. J Clin Invest 118:272-280
    • (2008) J Clin Invest , vol.118 , pp. 272-280
    • Xu, L.1    Rensing, N.2    Yang, X.F.3    Zhang, H.X.4    Thio, L.L.5    Rothman, S.M.6    Weisenfeld, A.E.7    Wong, M.8    Yamada, K.A.9
  • 40
    • 33751425456 scopus 로고    scopus 로고
    • Gamma glutamyl transpeptidase is a dynamic indicator of endothelial response to stroke
    • 16973162 10.1016/j.expneurol.2006.07.023 1:CAS:528:DC%2BD28Xht1Krt7zO
    • Yu C, Kastin AJ, Ding Y, Pan W (2007) Gamma glutamyl transpeptidase is a dynamic indicator of endothelial response to stroke. Exp Neurol 203:116-122
    • (2007) Exp Neurol , vol.203 , pp. 116-122
    • Yu, C.1    Kastin, A.J.2    Ding, Y.3    Pan, W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.