Leptin receptor mRNA in rat brain astrocytes

Peptides

Volumn 30, Issue 12, 2009, Pages 2275-2280

  Hsuchou, Hung ^a   Pan, Weihong ^a   Barnes, Maria J ^a   Kastin, Abba J ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

Astrocytes; Fluorescent in situ hybridization; Immunohistochemistry; Leptin; Lipopolysaccharide; mRNA; ObR; TNF

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; LEPTIN RECEPTOR; LIPOPOLYSACCHARIDE; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL STRUCTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; NERVE CELL CULTURE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ASTROCYTES; BLOTTING, WESTERN; BRAIN; CELL LINE, TUMOR; HYPOTHALAMUS; IN SITU HYBRIDIZATION, FLUORESCENCE; LIPOPOLYSACCHARIDES; POLYMERASE CHAIN REACTION; RATS; RECEPTORS, LEPTIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

MUS; RATTUS;

EID: 70449687899     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2009.08.023     Document Type: Article

References (21)

1. Banks W.A., Altmann J., Sapolsky R.M., Phllips-Conroy J.E., and Morley J.E. Serum leptin levels as a marker for a syndrome X-like condition in wild baboons. J Clin Endocrinol Metab 88 (2003) 1234-1240
2. Banks W.A., and Farrell C.L. Impaired transport of leptin across the blood-brain barrier in obesity is acquired and reversible. Am J Physiol 285 (2003) E10-E15
3. Bjørbæk C., Elmquist J.K., Michl P., Ahima R.S., van Bueren A., McCall A.L., et al. Expression of leptin receptor isoforms in rat brain microvessels. Endocrinology 139 (1998) 3485-3491
4. Cheunsuang O., and Morris R. Astrocytes in the arcuate nucleus and median eminence that take up a fluorescent dye from the circulation express leptin receptors and neuropeptide Y Y1 receptors. Glia 52 (2005) 228-233
5. Dall'Aglio C., Ceccarelli P., Pascucci L., Brecchia G., and Boiti C. Receptors for leptin and estrogen in the subcommissural organ of rabbits are differentially modulated by fasting. Brain Res 1124 (2006) 62-69
6. Dallaporta M., Pecchi E., Pio J., Jean A., Horner K.C., and Troadec J.D. Expression of leptin receptors by glial cells of the nucleus tractus solitarius: possible involvement in energy homeostasis. J Neuroendocrinol 21 (2009) 57-67
7. Elmquist J.K., Bjorbaek C., Ahima R.S., Flier J.S., and Saper C.B. Distributions of leptin receptor mRNA isoforms in the rat brain. J Comp Neurol 395 (1998) 535-547
8. Hsuchou H., He Y., Kastin A.J., Tu H., Markadakis E.N., Rogers R.C., et al. Obesity induces functional astrocytic leptin receptors in hypothalamus. Brain 132 (2009) 889-902
9. Kastin A.J., Banks W.A., Olson R.D., and Zadina J.E. Novel concepts from novel peptides. Ann NY Acad Sci 739 (1994) 1-10
10. Kastin A.J., and Pan W. Dynamic regulation of leptin entry into brain by the blood-brain barrier. Regul Pept 92 (2000) 37-43
11. Kastin A.J., Zadina J.E., Banks W.A., and Graf M.V. Misleading concepts in the field of brain peptides. Peptides 5 Suppl. 1 (1984) 249-253
12. Kurrimbux D., Gaffen Z., Farrell C.L., Martin D., and Thomas S.A. The involvement of the blood-brain and the blood-cerebrospinal fluid barriers in the distribution of leptin into and out of the rat brain. Neuroscience 123 (2004) 527-536
13. Morash B., Johnstone J., Leopold C., Li A., Murphy P., Ur E., et al. The regulation of leptin gene expression in the C6 glioblastoma cell line. Mol Cell Endocrinol 165 (2000) 97-105
14. Pan W., Hsuchou H., He Y., Sakharkar A., Cain C., Yu C., et al. Astrocyte leptin receptor (ObR) and leptin transport in adult-onset obese mice. Endocrinology 149 (2008) 2798-2806
15. Pan W., Hsuchou H., Tu H., and Kastin A.J. Developmental changes of leptin receptors in cerebral microvessels: unexpected relation to leptin transport. Endocrinology 149 (2008) 877-885
16. Pan W., and Kastin A.J. Adipokines and the blood-brain barrier. Peptides 28 (2007) 1317-1330
17. Pan W., and Kastin A.J. Evolution of neuropeptide concepts illustrated by MIF-1 and MSH. In: Shioda S., Homma I., and Kato N. (Eds). Transmitters and modulators in health and disease (2009), Springer, Tokyo 3-17
18. Pan W, Yu C, Hsuhou H, Khan RS, Kastin AJ, Cerebral microvascular IL15 is a novel mediator of TNF action. J Neurochem; in press, PMID 19719822.
19. Yu C., Kastin A.J., Ding Y., and Pan W. Gamma glutamyl transpeptidase is a dynamic indicator of endothelial response to stroke. Exp Neurol 203 (2007) 116-122
20. Yu C., Kastin A.J., Tu H., and Pan W. Opposing effects of proteasomes and lysosomes on LIFR: modulation by TNF. J Mol Neurosci 32 (2007) 80-89
21. Zlokovic B.V., Jovanovic S., Miao W., Samara S., Verma S., and Farrell C.L. Differential regulation of leptin transport by the choroid plexus and blood-brain barrier and high affinity transport systems for entry into hypothalamus and across the blood-cerebrospinal fluid barrier. Endocrinology 141 (2000) 1434-1441