Variations in the protein level of Omi/HtrA2 in the heart of aged rats may contribute to the increased susceptibility of cardiomyocytes to ischemia/reperfusion injury and cell death: Omi/HtrA2 and aged heart injury

Age

Volumn 35, Issue 3, 2013, Pages 733-746

  Wang, Ke ^a   Zhang, Jie ^b   Liu, Jingyi ^b   Tian, Jue ^c   Wu, Ye ^b   Wang, Xiaoliang ^b   Quan, Lin ^a   Xu, Haibo ^a   Wang, Wen ^a   Liu, Huirong ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b SHANXI MEDICAL UNIVERSITY   (China)

^c NINGXIA MEDICAL UNIVERSITY   (China)

Author keywords

Aging; Apoptosis; Myocardial ischemia reperfusion; Omi HtrA2; XIAP

Indexed keywords

CASPASE 3; MESSENGER RNA; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SERINE PROTEINASE OMI; X LINKED INHIBITOR OF APOPTOSIS;

ADULT ANIMAL; AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DISEASE EXACERBATION; ENZYME ACTIVITY; GENE EXPRESSION; GENE TRANSLOCATION; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MALE; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; OMI GENE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REPERFUSION INJURY; SMAC GENE; XIAP GENE;

AGING; ANIMALS; BLOTTING, WESTERN; CARRIER PROTEINS; CELL DEATH; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; IN SITU NICK-END LABELING; MALE; MITOCHONDRIA, HEART; MITOCHONDRIAL PROTEINS; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; NERVE TISSUE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA-BINDING PROTEINS; SERINE ENDOPEPTIDASES; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84880573421     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-012-9406-x     Document Type: Article

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