High glucose, insulin and free fatty acid concentrations synergistically enhance perilipin 3 expression and lipid accumulation in macrophages

Metabolism: Clinical and Experimental

Volumn 62, Issue 8, 2013, Pages 1168-1179

  Fan, Bin ^a   Gu, Jian Qiu ^a   Yan, Rong ^a   Zhang, Hong ^a   Feng, Juan ^a   Ikuyama, Shoichiro ^b  

^a CHINA MEDICAL UNIVERSITY   (China)

^b KYUSHU UNIVERSITY BEPPU HOSPITAL   (Japan)

Author keywords

Foam cell; Metabolic syndrome; Perilipin; PLIN2; PLIN3

Indexed keywords

CHOLESTEROL; GLUCOSE; INSULIN; MESSENGER RNA; OLEIC ACID; PERILIPIN; PERILIPIN 2; PERILIPIN 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; FOAM CELL; LIPID ANALYSIS; LIPID STORAGE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; STAINING; WESTERN BLOTTING;

ADIPOSE DIFFERENTIATION-RELATED PROTEIN; ADRP; FFAS; FOAM CELL; FREE FATTY ACIDS; G PROTEIN-COUPLED RECEPTOR; GPR; LDS; LIPID DROPLETS; METABOLIC SYNDROME; OA; OLEIC ACID; OXIDATIVE TISSUE-ENRICHED PAT PROTEIN; OXPAT; PERILIPIN; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PHOSPHATIDYLINOSITOL 3-KINASE.; PI3K; PLIN; PLIN2; PLIN3; PPAR; TAGS; TAIL INTERACTING PROTEIN OF 47KDA; TIP47; TRIACYLGLYCERIDES;

ANIMALS; AZO COMPOUNDS; BLOTTING, WESTERN; CARRIER PROTEINS; CHOLESTEROL; COLORING AGENTS; FATTY ACIDS, NONESTERIFIED; GLUCOSE; HYPOGLYCEMIC AGENTS; INSULIN; LIPID METABOLISM; MACROPHAGES; MICE; MICE, INBRED C57BL; OLEIC ACID; PHOSPHATIDYLINOSITOL 3-KINASES; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SRC-FAMILY KINASES; TRANSFECTION; TRIGLYCERIDES;

EID: 84880572651     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2013.02.013     Document Type: Article

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