Insulin Up-regulates Tumor Necrosis Factor-α Production in Macrophages through an Extracellular-regulated Kinase-dependent Pathway

Journal of Biological Chemistry

Volumn 276, Issue 35, 2001, Pages 32531-32537

  Tada Iida, Kaoruko ^a   Shimano, Hitoshi ^a   Kawakami, Yasushi ^a   Sone, Hirohito ^a   Toyoshima, Hideo ^a   Suzuki, Seiji ^a   Asano, Tomoichiro ^b   Okuda, Yukichi ^a   Yamada, Nobuhiro ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; ENZYME INHIBITION; ENZYMES; INSULIN; RNA; TUMORS;

GENE EXPRESSION; MACROPHAGES;

BIOCHEMISTRY;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; INSULIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; WORTMANNIN; ENZYME INHIBITOR; FLAVONOID; IMIDAZOLE DERIVATIVE; PYRIDINE DERIVATIVE;

ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA MICROARRAY; ENZYME REGULATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HYPERINSULINEMIA; ISCHEMIC HEART DISEASE; MACROPHAGE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN SECRETION; REGULATORY MECHANISM; RISK FACTOR; SIGNAL TRANSDUCTION; CELL CULTURE; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETICS; IMMUNOLOGY; KINETICS; PHYSIOLOGY; PROTEIN SYNTHESIS;

CELL LINE; ENZYME INHIBITORS; FLAVONOIDS; GENE EXPRESSION REGULATION; HUMANS; IMIDAZOLES; INSULIN; KINETICS; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN BIOSYNTHESIS; PYRIDINES; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035980021     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009894200     Document Type: Article

References (42)

1. Kelley, J. (1990) Am. Rev. Respir. Dis. 141, 765-788
2. Bonta, I. L., and Ben Efraim, S. (1993) J. Leukocyte Biol. 54, 613-626
3. Belardelli, F. (1995) Acta Pathol. Microbiol. Immunol. 103, 161-179
4. Steinberg, D. (1990) Ann. N. Y. Acad. Sci. 598, 125-135
5. Steinberg, D. (1997) J. Biol. Chem. 272, 20963-20966
6. Ross, R. (1993) Nature 362, 801-809
7. Jarrett, R. J., McCartney, P., and Keen, H. (1982) Diabetologia 22, 79-84
8. Pyorala, K., Laakso, M., and Unsitupa, M. (1987) Diabetes Metab. Rev. 3, 463-524
9. Reaven, G. M. (1988) Diabetes 37, 1595-1607
10. Kaplan, N. M. (1989) Arch. Intern. Med. 149, 1514-1520
11. Zavaroni, I., Bonora, E., Pagliara, M., Dall'Aglio, E., Luchetti, L., Buonanno, G., Bonati, P. A., Bergonzani, M., Gnudi, L., Passeri, M., and Reaven, G. (1989) N. Engl. J. Med. 320, 702-706
12. Stout, R. W. (1970) Br. Med. J. 19, 685-687
13. Sato, Y., Shiraishi, S., Oshida, Y., Ishiguro, T., and Sakamoto, N. (1989) Diabetes 38, 91-96
14. Stout, R. W., Bierman, E. L., and Ross, R. (1975) Circ. Res. 36, 319-327
15. Pfeifle, B., and Ditschuneit, H. (1981) Diabetologia 20, 155-158
16. Tsuchiya, S., Yamabe, M., Yamaguchi, Y., Kobayashi, Y., Konno, T., and Tada, K. (1980) Int. J. Cancer 26, 171-176
17. Tsuchiya, S., Kobayashi, Y., Goto, Y., Okumura, H., Nakae, S., Konno, T., and Tada, K. (1982) Cancer Res. 42, 1530-1536
18. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. (1951) J. Biol. Chem. 193, 265-275
19. Sakurai, A., Satomi, N., and Haranaka, K. (1985) Cancer Immunol. Immunother. 20, 6-10
20. Gifford, G. E., and Lohmann Matthes, M. L. (1986) Int. J. Cancer 38, 135-137
21. Pang, L., Sawada, T., Decker, S. J., and Saltiel, A. R. (1995) J. Biol. Chem. 270, 13585-13588
22. Schwende, H., Fitzke, E., Ambs, P., and Dieter, P. (1996) J. Leukocyte Biol. 59, 555-561
23. Remick, D. G., Scales, W. E., May, M. A., Spengler, M., Nguyen, D., and Kunkel, S. L. (1988) Lab. Invest. 59, 809-816
24. Kovacs, E. J., Radzioch, D., Young, H. A., and Varesio, L. (1988) J. Immunol 141, 3101-3105
25. Hambleton, J., McMahon, M., and DeFranco, A. L. (1995) J. Exp. Med. 182, 147-154
26. Higashimoto, Y., Ohata, M., Iwamoto, Y., Fujimoto, H., Uetani, K., Suruda, T., Nakamura, Y., Nakai, S., and Funasako, M. (1995) Respiration 62, 89-94
27. Means, T. K., Pavlovich, R. P., Roca, D., Vermeulen, M. W., and Fenton, M. J. (2000) J. Leukocyte Biol. 67, 885-893
28. Valledor, A. F., Comalada, M., Xaus, J., and Celada, A. (2000) J. Biol. Chem. 275, 7403-7409
29. Renier, G., Clément, I., Desfaits, A. C., and Lambert, A. (1996) Endocrinology 137, 4611-4618
30. Miller, L., and Hunt, J. S. (1996) J. Immunol. 160, 5098-5104
31. Haeffner, A., Thieblemont, N., Deas, O., Marelli, O., Charpentier, B., Senik, A., Wright, S. D., Haeffner Cavaillon, N., and Hirsch, F. (1997) J. Immunol. 158, 1310-1314
32. Taherzadeh, S., Sharma, S., Chhajlani, V., Gantz, I., Rajora, N., Demitri, M. T., Kelly, L., Zhao, H., Ichiyama, T., Catania, A., and Lipton, J. M. (1999) Am. J. Physiol. 276, R1269-R1294
33. Lowe, W. L., and Leroith, D. (1966) Biochem. Biophys. Res. Commun. 134, 532-538
34. American Diabetes Association (1989) Diabetes Care 12, 573-579
35. Schwartz, C. J., Valente, A. J., Sprague, E. A., Kelley, J. L., Suenram, C. A., and Rozek, M. M. (1985) Ann. N. Y. Acad. Sci. 454, 115-120
36. Hansson, G. K. (1997) Curr. Opin. Lipidol. 8, 301-311
37. Galis, Z. S., Muszynski, M., Sukhova, G. K., Simon Morrissey, E., and Libby, P. (1995) Ann. N. Y. Acad. Sci. 748, 501-507
38. Spiecker, M., Peng, H. B., and Liao, J. K. (1997) J. Biol. Chem. 272, 30969-30974
39. Yoshizumi, M., Kourembanas, S., Temizer, D. H., Cambria, R. P., Quertermous, T., and Lee, M. E. (1992) J. Biol. Chem. 267, 9467-9469
40. Fen, Z., Dhadly, M. S., Yoshizumi, M., Hilkert, R. J., Quertermous, T., Eddy, R. L., Shows, T. B., and Lee, M. E. (1993) Biochemistry 32, 7932-7938
41. Libby, P., Sukhova, G., Lee, R. T., and Galis, Z. S. (1995) J. Cardiovasc. Pharmacol. 26, S9-S12
42. Rayment, N. B., Moss, E., Faulkner, L., Brickell, P. M., Davies, M. J., Woolf, N., and Katz, D. R. (1996) Cardiovasc. Res. 32, 1123-1130