Cyclophosphamide perturbs cytosine methylation in Jurkat-T cells through LSD1-mediated stabilization of DNMT1 protein

Chemical Research in Toxicology

Volumn 24, Issue 11, 2011, Pages 2040-2043

  Zhang, Jing ^a,b   Yuan, Bifeng ^a   Zhang, Fan ^a   Xiong, Lei ^a   Wu, Jiang ^a   Pradhan, Sriharsa ^c   Wang, Yinsheng ^a  

^a SHAANXI NORMAL UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NEW ENGLAND BIOLABS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARMUSTINE; CISPLATIN; CYCLOPHOSPHAMIDE; CYTARABINE; CYTOSINE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; DOXORUBICIN; ETOPOSIDE; GENOMIC DNA; HISTONE LYSINE METHYLTRANSFERASE; HISTONE LYSINE METHYLTRANSFERASE SET7; LYSINE; LYSINE DERIVATIVE; LYSINE SPECIFIC DEMETHYLASE 1; MESSENGER RNA; PROTEASOME; UNCLASSIFIED DRUG;

ARTICLE; DNA METHYLATION; DRUG MECHANISM; ENZYME DEGRADATION; LEUKEMIA CELL LINE; PROTEIN EXPRESSION; PROTEIN STABILITY; REGULATORY MECHANISM; TIME; TREATMENT DURATION;

ANTINEOPLASTIC AGENTS, ALKYLATING; BLOTTING, WESTERN; CYCLOPHOSPHAMIDE; CYTOSINE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONE DEMETHYLASES; HUMANS; JURKAT CELLS; LYSINE; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTEASOME ENDOPEPTIDASE COMPLEX; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 81755166995     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx2003849     Document Type: Article

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